| Assay ID | Title | Year | Journal | Article |
|---|
| AID1063854 | Antagonist activity at NPYY2 receptor (unknown origin) assessed as inhibition of PYY-induced [33S]-GTPgammaS binding | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063847 | Cmax in rat at 30 mg/kg, ip after 30 mins | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID426875 | Binding affinity to neuropeptide Y2 receptor | 2009 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15
| The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists. |
| AID1063853 | Selectivity ratio of human NPYY4 receptor to NPYY2 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063850 | Bioavailability in rat at 30 mg/kg, ip | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063861 | Displacement of [125I]-NPY from NPYY2 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063846 | In vivo occupancy of NPYY5 receptor in rat hypothalamus at 30 mg/kg, ip | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID616660 | Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor. |
| AID146902 | Binding affinity towards human NPY Y2 receptor was determined using [35S]GTP-gamma-S, radioligand | 2004 | Bioorganic & medicinal chemistry letters, Mar-08, Volume: 14, Issue:5
| Novel non-peptidic neuropeptide Y Y2 receptor antagonists. |
| AID1063851 | Selectivity ratio of human NPYY5 receptor to NPYY2 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063852 | Selectivity ratio of human NPYY1 receptor to NPYY2 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1063848 | Half life in rat plasma at 30 mg/kg, ip | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID426876 | Antagonist activity at human neuropeptide Y2 receptor by [35]GTPgammaS assay | 2009 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15
| The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists. |
| AID1063849 | Ratio of drug level from brain to plasma in rat at 30 mg/kg, ip after 30 mins | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Ligands of the neuropeptide Y Y2 receptor. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346410 | Human Y2 receptor (Neuropeptide Y receptors) | 2004 | The Journal of pharmacology and experimental therapeutics, Mar, Volume: 308, Issue:3
| Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |