| Assay ID | Title | Year | Journal | Article |
|---|
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1700426 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR/DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS binding after 60 mins by beta-galactosidase based scintillation counting method | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1610000 | Inhibition of delta opioid receptor (unknown origin) expressed in human UO5S cells assessed as increase in beta arrestin recruitment | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1609997 | Inhibition of delta opioid receptor (unknown origin) expressed in human UO5S cells by [35S]-GTPgammaS binding assay | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1700416 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS binding after 60 mins by beta-galactosidase based scintillation counting method | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700422 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS binding at 10 uM after 60 mins by beta-galactosidase based scintillation counting method relative to DAMGO | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1610001 | Inhibition of mu opioid receptor (unknown origin) assessed as increase in beta arrestin recruitment relative to control | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1609995 | Inhibition of mu opioid receptor (unknown origin) expressed in human UO5S cells by [35S]-GTPgammaS binding assay | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1700427 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR/DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS binding at 10 uM after 60 mins by beta-galactosidase based scintillation counting method relative to DAMGO | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1609998 | Inhibition of delta opioid receptor (unknown origin) expressed in human UO5S cells by [35S]-GTPgammaS binding assay relative to control | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1609996 | Inhibition of mu opioid receptor (unknown origin) expressed in human UO5S cells by [35S]-GTPgammaS binding assay relative to control | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1700436 | Antinociceptive activity in CD-1 mouse model of thermal-induced nociception administered subcutaneously by warm water tail-flick assay | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700442 | Induction of respiratory depression in CD-1 mouse assessed as reduction in respiratory rate at 2.6 mg/kg, sc measured 15 mins post-treatment up to 35 mins by pulse oximetric method relative to control | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700428 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR/DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment after 60 mins by Pathhunter chemiluminescence assay | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700421 | Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment after 60 mins by Pathhunter chemiluminescence assay | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1609999 | Inhibition of mu opioid receptor (unknown origin) expressed in human UO5S cells assessed as increase in beta arrestin recruitment | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1700423 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment at 10 uM after 60 mins by Pathhunter Chemiluminescence assay relative to DAMGO | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700429 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR/DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment at 10 uM after 60 mins by Pathhunter chemiluminescence assay relative to DAMGO | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1610002 | Inhibition of delta opioid receptor (unknown origin) assessed as increase in beta arrestin recruitment relative to control | 2019 | European journal of medicinal chemistry, Dec-01, Volume: 183 | Progress in the development of more effective and safer analgesics for pain management. |
| AID1700419 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment after 60 mins by Pathhunter chemiluminescence assay | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700425 | Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitment at 10 uM after 60 mins by Pathhunter chemiluminescence assay relative to DELT II | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| AID1700424 | Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS binding at 10 uM after 60 mins by beta-galactosidase based scintillation counting method relative to DELT II | 2020 | Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22
| Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |