Assay ID | Title | Year | Journal | Article |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID385124 | Antiviral activity against HIV1 in human C8166 cells assessed as prevention of virus-induced cytopathic effect | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4
| Lignans from Kadsura angustifolia. |
AID1304222 | Growth inhibition of Italian ryegrass assessed as reduction in root growth at 1 mM after 5 days | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1304215 | Antifungal activity against Colletotrichum lagenarium assessed as mycelial colony growth levels at 0.25 mM after 5 days by caliper analysis | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID313421 | Antioxidant activity against LDL-oxidation assessed as conjugated diene formation lag time at 1.0 uM | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1464074 | Antibacterial activity against Staphylococcus aureus | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1304219 | Antibacterial activity against Salmonella choleraesuis subsp. choleraesuis JCM 6977 after 24 hrs by 2 fold dilution method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID46498 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 10 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID1304214 | Antifungal activity against Bipolaris oryzae assessed as mycelial colony growth levels at 0.25 mM after 3 days by caliper analysis | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID46501 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 30 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID46500 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 20 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID1155650 | Neuroprotective activity against amyloid beta (25 to 35)-induced cell death in human SH-SY5Y cells assessed as cell viability at 10 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID1304218 | Antibacterial activity against Listeria denitrificans JCM 11481 after 24 hrs by 2 fold dilution method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1464072 | Antibacterial activity against multidrug-resistant Mycobacterium tuberculosis | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1155649 | Neuroprotective activity against amyloid beta (25 to 35)-induced cell death in human SH-SY5Y cells assessed as cell viability at 2 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID1541175 | Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability at 10 uM by CCK-8 assay | 2019 | Journal of natural products, 11-22, Volume: 82, Issue:11
| Lignans from |
AID1155648 | Neuroprotective activity against amyloid beta (25 to 35)-induced cell death in human SH-SY5Y cells assessed as cell viability at 0.4 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID1304225 | Selectivity index, ratio of IC50 for fall armyworm sf9 cells to IC50 for Cytotoxicity against human HeLa cells | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID46497 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 100 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID1464091 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as inhibition of mycobacterial growth incubated for 2 weeks by MABA method | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1304211 | Antilarvicidal activity against Culex pipiens larvae after 24 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1304221 | Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by WST-8 reduction assay | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID429824 | Cytotoxicity against human C8166 cells by MTT assay | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| Lignans with anti-HIV activity from Schisandra propinqua var. sinensis. |
AID1304216 | Antibacterial activity against Bacillus subtilis subsp. subtilis NBRC 13719 after 24 hrs by 2 fold dilution method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1464093 | Antimycobacterial activity against isoniazid/rifampicin/streptomycin-resistant Mycobacterium tuberculosis G133 assessed as inhibition of mycobacterial growth incubated for 2 weeks by MABA method | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID46502 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 3 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID313419 | Antioxidant activity assessed as inhibition of LDL-oxidation at 20 uM by TBARS assay | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1304217 | Antibacterial activity against Staphylococcus aureus subsp. aureus NBRC 14462 after 24 hrs by 2 fold dilution method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID313424 | Antioxidant activity assessed as inhibition of copper-mediated LDL-oxidation at 10 uM by relative electrophoretic mobility method | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1155647 | Neuroprotective activity against amyloid beta (25 to 35)-induced cell death in human SH-SY5Y cells assessed as cell viability at 0.08 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID313427 | Antioxidant activity against LDL-oxidation in human THP1 cells assessed as malondialdehyde level per mg of LDL protein at 1 uM | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1155643 | Antioxidant activity assessed as 150 uM DPPH free radical scavenging activity under dark condition after 30 mins by microplate reader analysis | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID1464087 | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 24 hrs by trypan blue staining based assay | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID313428 | Antioxidant activity against LDL-oxidation in human THP1 cells assessed as malondialdehyde level per mg of LDL protein at 5 uM | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1304220 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by WST-8 reduction assay | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1304226 | Selectivity index, ratio of IC50 for fall armyworm Sf9 cells to IC50 for Cytotoxicity against human HL60 cells | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1464071 | Antibacterial activity against methicillin-resistant Staphylococcus aureus | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID385126 | Selectivity index, Ratio of EC50 for HIV1 to CC50 for human C8166 cells | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4
| Lignans from Kadsura angustifolia. |
AID313426 | Antioxidant activity assessed as inhibition of apoB100 fragmentation at 10 uM by SDS-PAGE method | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1304223 | Growth inhibition of Italian ryegrass assessed as reduction in shoot growth at 1 mM after 5 days | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID46503 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 60 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID1155644 | Antioxidant activity assessed as 300 uM DPPH free radical scavenging activity under dark condition after 30 mins by microplate reader analysis | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID1541174 | Inhibition of LPS-induced NO production in mouse RAW264.7 cells incubated for 24 hrs in presence of LPS by Griess reagent based assay | 2019 | Journal of natural products, 11-22, Volume: 82, Issue:11
| Lignans from |
AID468191 | Antiinflammatory activity in rat PMNC assessed as inhibition of platelet activating factor-induced beta-glucuronidase release at 10 uM treated 15 mins before PAF by spectrophotometry | 2009 | Journal of natural products, Dec, Volume: 72, Issue:12
| Chemical constituents of the bark of Machilus wangchiana and their biological activities. |
AID429826 | Selectivity index, ratio of CC50 for human C8166 cells to EC50 for HIV1 3B | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| Lignans with anti-HIV activity from Schisandra propinqua var. sinensis. |
AID313420 | Antioxidant activity against LDL-oxidation by TBARS assay | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID313425 | Antioxidant activity assessed as inhibition of apoB100 fragmentation at 20 uM by SDS-PAGE method | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID46496 | Inhibitory activity against HIV Tat-regulated Transactivation in COS cells. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID46499 | Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 1 uM. | 1998 | Journal of medicinal chemistry, Jul-30, Volume: 41, Issue:16
| Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. |
AID1464092 | Antimycobacterial activity against isoniazid/rifampicin/ethambutol-resistant Mycobacterium tuberculosis G122 assessed as inhibition of mycobacterial growth incubated for 2 weeks by MABA method | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1304212 | Antifungal activity against Alternaria alternata assessed as mycelial colony growth at 0.25 mM after 3 days by caliper analysis | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1155645 | Antioxidant activity assessed as reduction of TPTZ-Fe3+ to TPTZ-Fe2+ after 5 mins by FRAP assay | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6
| Lignans from the fruit of Schisandra glaucescens with antioxidant and neuroprotective properties. |
AID385125 | Cytotoxicity against human C8166 cells by MTT assay | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4
| Lignans from Kadsura angustifolia. |
AID429825 | Antiviral activity against HIV1 3B in human C8166 cells assessed as inhibition of virus-induced cytopathogenicity | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| Lignans with anti-HIV activity from Schisandra propinqua var. sinensis. |
AID313423 | Antioxidant activity assessed as inhibition of copper-mediated LDL-oxidation at 20 uM by relative electrophoretic mobility method | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds. |
AID1304224 | Cytotoxicity against fall armyworm Sf9 cells assessed as reduction in cell viability after 48 hrs by WST-8 reduction assay | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1464094 | Selectivity index, ratio of IC50 for cytotoxicity against African green monkey Vero cells to MIC for Mycobacterium tuberculosis H37Rv ATCC 27294 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1304213 | Antifungal activity against Fusarium solani assessed as mycelial colony growth levels at 0.25 mM after 3 days by caliper analysis | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13
| Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids. |
AID1464073 | Antibacterial activity against Bacillus subtilis | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
AID1464075 | Antibacterial activity against Listeria denitrificans | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20
| meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |