| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID566338 | Metabolic stability in mouse microsomes assessed as decrease in parent compound level after 30 mins by LC/MS | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566340 | Inhibition of etoposide-induced CHK2 bandshift in human HT-29 cells by gel electrophoresis | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566495 | Inhibition of SRPK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566474 | Inhibition of CHK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566458 | Inhibition of S6K1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566489 | Inhibition of NEK2a at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566448 | Inhibition of p38beta MAPK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566471 | Inhibition of CAMK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566512 | Inhibition of VEGFR at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566457 | Inhibition of SGK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566482 | Inhibition of BRSK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566456 | Inhibition of PKBbeta at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566444 | Inhibition of ERK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566476 | Inhibition of GSK3b at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566516 | Inhibition of TBK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566511 | Inhibition of IGF-1R at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566505 | Inhibition of FGF-R1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566451 | Inhibition of ERK8 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566506 | Inhibition of IRR at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566459 | Inhibition of PKA at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566460 | Inhibition of ROCK 2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566492 | Inhibition of PIM1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566483 | Inhibition of MELK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566524 | Inhibition of LKB1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566450 | Inhibition of p38delta MAPK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566449 | Inhibition of p38-gamma MAPK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566503 | Inhibition of Lck at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566509 | Inhibition of SYK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566469 | Inhibition of PRAK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566526 | Inhibition of TTK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566488 | Inhibition of DYRK3 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566468 | Inhibition of MAPKAP-K2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566481 | Inhibition of MARK3 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566463 | Inhibition of PKCzeta at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566462 | Inhibition of PKCalpha at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566473 | Inhibition of PHK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566502 | Inhibition of Src at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566344 | Inhibition of CHK1 by DELFIA assay | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566446 | Inhibition of JNK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566466 | Inhibition of MNK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566498 | Inhibition of HIPK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566472 | Inhibition of SmMLCK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566486 | Inhibition of DYRK1A at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566461 | Inhibition of PRK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566339 | Cytotoxicity against human HT-29 cells by SRB colorimetric assay | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566523 | Inhibition of MLK3 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566479 | Inhibition of Aurora B at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566515 | Inhibition of EPH-B3 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566453 | Inhibition of RSK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566496 | Inhibition of MST2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566465 | Inhibition of MSK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566500 | Inhibition of PAK5 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566507 | Inhibition of EPHA2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566464 | Inhibition of PKD1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566452 | Inhibition of RSK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566497 | Inhibition of EF2K at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566517 | Inhibition of IKKepsilon at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566520 | Inhibition of NUAK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566510 | Inhibition of YES1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566521 | Inhibition of MLK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566519 | Inhibition of IRAK4 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566345 | Selectivity ratio of IC50 for CHK2 to IC50 for CHK1 | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566508 | Inhibition of MST4 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566467 | Inhibition of MNK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566487 | Inhibition of DYRK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566494 | Inhibition of PIM3 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566501 | Inhibition of PAK6 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566447 | Inhibition of p38alpha MAPK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566480 | Inhibition of AMPK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566522 | Inhibition of MINK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566342 | Inhibition of CHK2 phosphorylation at Ser516 in human HT-29 cells at 1 uM by gel electrophoresis | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566343 | Inhibition of CHK2 by DELFIA assay | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566518 | Inhibition of GCK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566346 | Inhibition of human ERG at 10 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566484 | Inhibition of CK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566491 | Inhibition of IKKb at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566443 | Inhibition of ERK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566455 | Inhibition of PKBalpha at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566470 | Inhibition of CAMKKbeta at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566454 | Inhibition of PDK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566477 | Inhibition of CDK2/CyclinA at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566485 | Inhibition of CK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566478 | Inhibition of PLK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566504 | Inhibition of CSK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566513 | Inhibition of BTK at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566341 | Inhibition of CHK2 phosphorylation at Thr68 in human HT-29 cells at 1 uM by gel electrophoresis | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566499 | Inhibition of PAK4 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566493 | Inhibition of PIM2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566514 | Inhibition of IR-HIS at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566347 | Inhibition of MKK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566475 | Inhibition of CHK2 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566525 | Inhibition of HER4 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566490 | Inhibition of NEK6 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID566445 | Inhibition of JNK1 at 1 uM | 2011 | Journal of medicinal chemistry, Jan-27, Volume: 54, Issue:2
| Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. |
| AID1347412 | qHTS assay to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: Counter screen cell viability and HiBit confirmation | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347411 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1345650 | Human checkpoint kinase 1 (CHK1 subfamily) | 2011 | Cancer research, Jan-15, Volume: 71, Issue:2
| CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. |
| AID1345648 | Human checkpoint kinase 2 (RAD53 family) | 2011 | Cancer research, Jan-15, Volume: 71, Issue:2
| CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |