| Assay ID | Title | Year | Journal | Article |
|---|
| AID616715 | Binding affinity to dopamine D2L receptor | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus. |
| AID1185301 | Allosteric modulatory activity at FLAG-tagged human cytomegalovirus US28 receptor delta300 mutant expressed in HEK293T cells by PathDetectElk1 assay | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? |
| AID458777 | Activity at HCMV US28 receptor assessed as receptor-mediated inositol phosphate response | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
| Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28. |
| AID1185302 | Allosteric modulatory activity at FLAG-tagged human cytomegalovirus US28 receptor delta300 mutant expressed in HEK293T cells by PathDetectElk1 assay relative to basal level | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? |
| AID1360732 | Modulation of basal activity of HCMV US28 expressed in tetracyclin-induced HEK293 cells assessed as change in inositol phosphate accumulation at 10 uM using [3H]-myo-inositol by scintillation proximity assay relative to control | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID1360734 | Displacement of [125I]-CCL2 from HCMV US28 expressed in HEK293 cells at 10 uM after 3 hrs by gamma counting method relative to control | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID52703 | Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cells | 2002 | Journal of medicinal chemistry, Aug-15, Volume: 45, Issue:17
| Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists. |
| AID1185299 | Allosteric modulatory activity at FLAG-tagged wild type human cytomegalovirus US28 receptor expressed in HEK293T cells by PathDetectElk1 assay | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? |
| AID616711 | Inverse agonist activity at HCMV TB40/E US28 expressed in human HEK cells assessed as Elk-1 activation preincubated for 1 hrs measured after 20 to 24 hrs by luciferase reporter gene assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus. |
| AID52700 | Inhibitory activity against human Chemokine receptor type 1 expressed in chinese hamster ovary cells | 2002 | Journal of medicinal chemistry, Aug-15, Volume: 45, Issue:17
| Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists. |
| AID221355 | Inhibitory activity against [125I]-MIP-1 alpha binding to mouse CCR1 receptors. | 2001 | Journal of medicinal chemistry, Apr-26, Volume: 44, Issue:9
| Design, synthesis, and discovery of a novel CCR1 antagonist. |
| AID1185300 | Allosteric modulatory activity at FLAG-tagged wild type human cytomegalovirus US28 receptor expressed in HEK293T cells by PathDetectElk1 assay relative to basal level | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? |
| AID82371 | Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptor | 1999 | Journal of medicinal chemistry, Nov-04, Volume: 42, Issue:22
| Discovery of novel non-peptide CCR1 receptor antagonists. |
| AID616714 | Efficacy at HCMV TB40/E US28 expressed in human HEK cells assessed as Elk-1 activation preincubated for 1 hrs measured after 20 to 24 hrs by PathDetect trans Elk-1 reporter gene assay relative to control | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
| Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus. |
| AID1360735 | Displacement of [125I]-CCL4 from HCMV US28 expressed in HEK293 cells at 10 uM after 3 hrs by gamma counting method relative to control | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID1360731 | Modulation of basal activity of HCMV US28 expressed in tetracyclin-induced HEK293 cells assessed as change in inositol phosphate accumulation using [3H]-myo-inositol by scintillation proximity assay | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID458776 | Displacement of [125I]CCL5 from HCMV US28 receptor | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
| Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28. |
| AID44615 | Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cells | 1999 | Journal of medicinal chemistry, Nov-04, Volume: 42, Issue:22
| Discovery of novel non-peptide CCR1 receptor antagonists. |
| AID1360733 | Displacement of [125I]-CX3CL1 from HCMV US28 expressed in HEK293 cells at 10 uM after 3 hrs by gamma counting method relative to control | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID223365 | Inhibitory activity against [125I]-MIP-1 alpha binding to human CCR1 receptors. | 2001 | Journal of medicinal chemistry, Apr-26, Volume: 44, Issue:9
| Design, synthesis, and discovery of a novel CCR1 antagonist. |
| AID255657 | Effective concentration against US28-mediated inositol phosphate production in COS-7 cells | 2005 | Journal of medicinal chemistry, Oct-06, Volume: 48, Issue:20
| Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28. |
| AID255096 | Inhibitory concentration against chemokine receptor US28 expressed in COS-7 cells using [125I]-CCL5 | 2005 | Journal of medicinal chemistry, Oct-06, Volume: 48, Issue:20
| Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28. |
| AID1360738 | Modulation of basal activity of HCMV US28 delta300 mutant expressed in tetracyclin-induced HEK293 cells assessed as change in inositol phosphate accumulation using [3H]-myo-inositol by scintillation proximity assay | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID1360729 | Inverse agonist activity at HCMV US28 expressed in African green monkey COS7 cells assessed as inhibition of inositol phosphate accumulation using [3H]-myo-inositol by liquid scintillation counting method | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID1360739 | Modulation of basal activity of HCMV US28 delta300 mutant expressed in tetracyclin-induced HEK293 cells assessed as change in inositol phosphate accumulation at 10 uM using [3H]-myo-inositol by scintillation proximity assay relative to control | 2018 | European journal of medicinal chemistry, Jul-15, Volume: 155 | Ligand-selective small molecule modulators of the constitutively active vGPCR US28. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |