| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID95039 | Inhibition against human plasma Kallikrein at 2 mM | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID215237 | log1/Ki value was calculated against Trypsin | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID1463539 | Selectivity ratio of IC50 for human OCT1 expressed in HEK293 cells to IC50 for human OCT3 expressed in HEK293 cells | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID1463540 | Competitive inhibition of human OCT3 expressed in HEK293 cells up to 25 uM in presence of varying concentration of MPP+ by Lineweaver-Burk plot analysis | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID210572 | Inhibition against Tissue plasminogen activator at 1 mM | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID215831 | In vitro inhibition of HWMT human urokinase Plasminogen activator. | 2002 | Bioorganic & medicinal chemistry letters, Jan-21, Volume: 12, Issue:2
| Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. |
| AID157969 | Ability to inhibit human plasmin using Chromozym-PL as substrate | 2002 | Bioorganic & medicinal chemistry letters, Jan-21, Volume: 12, Issue:2
| Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. |
| AID215841 | Inhibition against Urokinase-type plasminogen activator | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID1463535 | Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID1463537 | Selectivity ratio of IC50 for human OCT2 expressed in HEK293 cells to IC50 for human OCT3 expressed in HEK293 cells | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID210743 | Ability to inhibit human tissue plasminogen activator stimulator at concentration of 1 mM | 2002 | Bioorganic & medicinal chemistry letters, Jan-21, Volume: 12, Issue:2
| Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. |
| AID1463536 | Inhibition of human OCT3 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID1463534 | Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18
| A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). |
| AID210841 | Inhibition against human plasma thrombin at 1.0 mM | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID6343 | Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cells | 1996 | Journal of medicinal chemistry, Sep-27, Volume: 39, Issue:20
| Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors. |
| AID215213 | Inhibition against Trypsin | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID215976 | log1/Ki value was calculated against Urokinase-type plasminogen activator | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID6339 | Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]GR-65630 radioligand. | 2001 | Bioorganic & medicinal chemistry letters, Jun-18, Volume: 11, Issue:12
| The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation. |
| AID157989 | Inhibition against human plasmin was determined at 0.5 mM | 1990 | Journal of medicinal chemistry, Nov, Volume: 33, Issue:11
| Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID493017 | Wombat Data for BeliefDocking | 2002 | Bioorganic & medicinal chemistry letters, Jan-21, Volume: 12, Issue:2
| Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |