ID Source | ID |
---|---|
PubMed CID | 2723842 |
CHEMBL ID | 1456330 |
SCHEMBL ID | 347929 |
SCHEMBL ID | 9497675 |
MeSH ID | M0534450 |
Synonym |
---|
AC-4806 |
sh-benzothiazole |
nsc3934 |
nsc-3934 |
2(3h)-benzothiazolethione, 5-chloro- |
5-chloro-2-benzothiazolethiol |
wln: t56 bn dsj csh hg |
2-benzothiazolethiol, 5-chloro- |
benzothiazole, 5-chloro-2-mercapto- |
5331-91-9 |
5-chloro-2-mercaptobenzothiazole , |
smr000129383 |
MLS000518963 , |
5-chloro-1,3-benzothiazole-2-thiol |
5-chloro-2-mercaptobenzothiazole, zinc salt |
53404-93-6 |
einecs 226-235-0 |
nsc 3934 |
EU-0002999 |
5-chloro-2-mercaptobenzothiazole, technical grade, >=90% |
MAYBRIDGE1_006216 |
STK396220 |
HMS559C12 |
inchi=1/c7h4clns2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3h,(h,9,10) |
nkydkcvznmnzcm-uhfffaoysa- |
5-chloro-3h-1,3-benzothiazole-2-thione |
AKOS001260730 |
AKOS000120378 |
NCGC00245945-01 |
HMS2502H14 |
2-metcapto-5-chloro-benzothiazole |
A829509 |
5-chlorobenzothiazole-2-thiol |
unii-r9099u429r |
r9099u429r , |
REGID_FOR_CID_2723842 |
AB00531 |
5-chlorobenzo[d]thiazole-2(3h)-thione |
FT-0620259 |
SCHEMBL347929 |
AB00128201-12 |
SCHEMBL9497675 |
5-chlorobenzo[d]thiazole-2-thiol |
cmbt |
5-chloro-benzothiazole-2-thiol |
5-chloro-benzothiazol-2-thiol |
W-105752 |
J-640164 |
5-chloro-3h-benzothiazole-2-thione |
5-chloro-1,3-benzothiazol-2-yl hydrosulfide |
bdbm59826 |
cid_2723842 |
5-chloranyl-3h-1,3-benzothiazole-2-thione |
CHEMBL1456330 |
5-chloro-2(3h)-benzothiazolethione |
5-chlorobenzothiazoline-2-thione |
2-mercapto-5-chlorobenzothiazole |
mfcd00005783 |
5-chloro-1,3-benzothiazole-2(3h)-thione |
DTXSID0022224 |
5-chloro-2,3-dihydro-1,3-benzothiazole-2-thione |
AS-63163 |
SR-01000414406-1 |
sr-01000414406 |
NCGC00245945-02 |
F15179 |
F0771-0819 |
5-chloro-2-mercaptobenzothiazine |
EN300-21446 |
Q27287987 |
CS-W015535 |
5-choro-2-mercapto benzothiazole |
SY048666 |
Z104497390 |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 8.9125 | 0.0447 | 17.8581 | 100.0000 | AID485294 |
Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 25.1189 | 0.6310 | 35.7641 | 100.0000 | AID504339 |
Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 35.4813 | 0.1778 | 14.3909 | 39.8107 | AID2147 |
apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 6.7016 | 0.7079 | 12.1943 | 39.8107 | AID720542 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 2.8184 | 0.0112 | 12.4002 | 100.0000 | AID1030 |
nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 5.0119 | 0.2818 | 9.7212 | 35.4813 | AID2326 |
IDH1 | Homo sapiens (human) | Potency | 22.3872 | 0.0052 | 10.8652 | 35.4813 | AID686970 |
euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 1.7783 | 0.0355 | 20.9770 | 89.1251 | AID504332 |
lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 27.9687 | 0.0366 | 19.6376 | 50.1187 | AID2100 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 0.0018 | 15.6638 | 39.8107 | AID894 |
serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 1.8888 | 0.1683 | 16.4040 | 67.0158 | AID720504 |
nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 22.1061 | 0.0079 | 8.2332 | 1,122.0200 | AID2546; AID2551 |
Vpr | Human immunodeficiency virus 1 | Potency | 25.1189 | 1.5849 | 19.6264 | 63.0957 | AID651644 |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 0.0580 | 10.6949 | 26.6086 | AID602310 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 25.1189 | 0.3162 | 12.7657 | 31.6228 | AID881 |
Alpha-synuclein | Homo sapiens (human) | Potency | 14.1254 | 0.5623 | 9.3985 | 25.1189 | AID652106 |
Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 25.1189 | 0.0063 | 8.2350 | 39.8107 | AID881 |
Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 0.8913 | 1.9953 | 25.5327 | 50.1187 | AID624287 |
TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 35.4813 | 1.7783 | 16.2081 | 35.4813 | AID652104 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Proteasome subunit beta type-8 | Homo sapiens (human) | IC50 (µMol) | 32.0000 | 0.0013 | 0.3698 | 5.0000 | AID1763210 |
M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 (µMol) | 14.7800 | 1.0000 | 27.8360 | 138.0800 | AID1619 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
MSRA protein | Bos taurus (cattle) | EC50 (µMol) | 103.9190 | 3.6370 | 4.0500 | 4.4630 | AID623963 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
AID1763210 | Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (20.00) | 29.6817 |
2010's | 5 (50.00) | 24.3611 |
2020's | 3 (30.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.91) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 10 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |