| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1346334 | Human HCA3 receptor (Hydroxycarboxylic acid receptors) | 2009 | Proceedings of the National Academy of Sciences of the United States of America, Mar-10, Volume: 106, Issue:10
| Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B. |
| AID1331205 | Activation of recombinant Methanosarcina thermophila gamma carbonic anhydrase at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1
| Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. |
| AID387527 | Activation of human recombinant CA2 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID458787 | Activation of Cryptococcus neoformans beta-carbonic anhydrase Can2 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Feb, Volume: 18, Issue:3
| Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids. |
| AID409993 | Activation of human recombinant CA3 by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID681113 | TP_TRANSPORTER: inhibition of L-tryptophan uptake in Xenopus laevis oocytes | 2001 | The Journal of biological chemistry, May-18, Volume: 276, Issue:20
| Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. |
| AID414330 | Activation of Methanothermobacter thermautotrophicus recombinant Cab by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 19, Issue:6
| Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids. |
| AID1815481 | Activation of human carbonic anhydrase 7 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID318345 | Activation of human recombinant CA9 catalytic domain by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines. |
| AID1815483 | Activation of human carbonic anhydrase 12 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID365829 | Activation of human recombinant CA3 at 10 uM by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15
| Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. |
| AID365828 | Activation of human recombinant CA2 at 10 uM by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15
| Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. |
| AID307898 | Activation of human recombinant CA6 by stopped flow CO2 hydrase method | 2007 | Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15
| Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines. |
| AID409986 | Activation of human recombinant CA2 by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID387533 | Activation of human recombinant CA5B after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID409988 | Activation of Methanobacterium thermoautotrophicum beta-class CA by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID725227 | Activation of Sulfurihydrogenibium yellowstonense recombinant CA by stopped flow CO2 hydrase method | 2013 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 23, Issue:4
| The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines. |
| AID387534 | Activation of human recombinant CA6 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID1751921 | Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry method | 2021 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 48 | Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate. |
| AID458784 | Activation of Candida albicans beta-carbonic anhydrase Nce103 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Feb, Volume: 18, Issue:3
| Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids. |
| AID1815485 | Activation of human carbonic anhydrase 14 by stopped flow CO2 hydrase assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID291061 | Activation of human recombinant CA1 by CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15
| Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines. |
| AID1398360 | Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake at 200 uM preincubated for 3 mins at 37 degC followed by washing with choline buffer and measured after 3 hrs by scintillation counting | 2018 | Journal of medicinal chemistry, 08-23, Volume: 61, Issue:16
| Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). |
| AID268622 | Activation of mouse recombinant CA13 by CO2 hydrase method | 2006 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 16, Issue:15
| Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines. |
| AID464320 | Activation of archaea Methanobacterium thermoautotrophicum recombinant carbonic anhydrase by stopped flow CO2 hydration method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids. |
| AID1815480 | Activation of human carbonic anhydrase 6 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID1660990 | Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysis | 2020 | Journal of medicinal chemistry, 08-13, Volume: 63, Issue:15
| The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. |
| AID387538 | Activation of mouse recombinant CA13 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID462828 | Activity of Stylophora pistillata carbonic anhydrase STPCA at 10 uM by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID462826 | Activity of human recombinant CA2at 10 uM by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID1397320 | Activation of human CA2 by stopped-flow CO2 hydration assay | | | |
| AID318346 | Activation of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines. |
| AID1331210 | Activation of Burkholderia pseudomallei gamma carbonic anhydrase assessed as Kcat at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1
| Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. |
| AID268621 | Activation of human recombinant CA2 by CO2 hydrase assay | 2006 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 16, Issue:15
| Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines. |
| AID464322 | Activation of Candida glabrata recombinant carbonic anhydrase by stopped flow CO2 hydration method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids. |
| AID387535 | Activation of human recombinant CA7 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID1331204 | Activation of recombinant human carbonic anhydrase 2 at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1
| Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. |
| AID208197 | In vitro inhibition of recombinant stromelysin catalytic domain. | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1
| A recombinant human stromelysin catalytic domain identifying tryptophan derivatives as human stromelysin inhibitors. |
| AID725229 | Activation of human recombinant CA2 by stopped flow CO2 hydrase method | 2013 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 23, Issue:4
| The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines. |
| AID307896 | Activation of human recombinant CA1 by stopped flow CO2 hydrase method | 2007 | Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15
| Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines. |
| AID462829 | Activation of human recombinant CA1 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID1815477 | Activation of human carbonic anhydrase 4 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID1815475 | Activation of human carbonic anhydrase 2 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID307897 | Activation of human recombinant CA2 by stopped flow CO2 hydrase method | 2007 | Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15
| Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines. |
| AID1815474 | Activation of human carbonic anhydrase 1 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID387536 | Activation of human recombinant CA9 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID1331206 | Activation of Burkholderia pseudomallei gamma carbonic anhydrase at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1
| Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. |
| AID409984 | Activation of human recombinant CA1 by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID1815479 | Activation of human carbonic anhydrase 5B by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID414329 | Activation of human recombinant CA2 by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 19, Issue:6
| Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids. |
| AID291067 | Activation of of human recombinant CA14 by CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15
| Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines. |
| AID318344 | Activation of human recombinant CA2 by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines. |
| AID462831 | Activation of human full length CA6 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID409990 | Activation of Methanosarcina thermophila Zinc(2)-derived gamma-class CA by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID291065 | Activation of human recombinant CA7 by CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15
| Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines. |
| AID462825 | Activity of human recombinant CA1 at 10 uM by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID1398359 | Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC followed by washing with choline buffer and measured after 3 hrs by scintillation counting analysis r | 2018 | Journal of medicinal chemistry, 08-23, Volume: 61, Issue:16
| Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). |
| AID387539 | Activation of human recombinant CA14 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID409992 | Activation of Methanosarcina thermophila cobalt(2)-derived gamma-class CA by stopped-flow CO2 hydrase assay | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23
| Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. |
| AID1815478 | Activation of human carbonic anhydrase 5A by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID387532 | Activation of human recombinant CA5A after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID1815484 | Activation of human carbonic anhydrase 13 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID725226 | Activation of Sulfurihydrogenibium azorense recombinant alpha carbonic anhydrase by stopped flow CO2 hydrase method | 2013 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 23, Issue:4
| The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines. |
| AID365827 | Activation of human recombinant CA1 at 10 uM by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15
| Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. |
| AID1331203 | Activation of recombinant human carbonic anhydrase 1 at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1
| Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. |
| AID1398361 | Trans-stimulation of human LAT1 expressed in TREx HEK293 cells assessed as induction of [3H]-gabapentin efflux at 200 uM after 3 mins by scintillation counting analysis relative to L-phenylalanine | 2018 | Journal of medicinal chemistry, 08-23, Volume: 61, Issue:16
| Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). |
| AID462832 | Activation of Stylophora pistillata carbonic anhydrase STPCA by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID365830 | Activation of human recombinant truncated CA4 at 10 uM by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15
| Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. |
| AID268620 | Activation of human recombinant CA1 by CO2 hydrase assay | 2006 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 16, Issue:15
| Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines. |
| AID1815476 | Activation of human carbonic anhydrase 3 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID464319 | Activation of human recombinant carbonic anhydrase isoenzyme 2 by stopped flow CO2 hydration method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids. |
| AID305777 | Activation of human recombinant carbonic anhydrase 5B by stopped-flow CO2 hydrase method | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5
| Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines. |
| AID387530 | Activation of human recombinant CA3 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID464321 | Activation of Saccharomyces cerevisiae recombinant Nce103p by stopped flow CO2 hydration method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids. |
| AID318343 | Activation of human recombinant CA1 by stopped-flow CO2 hydration method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
| Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines. |
| AID1281543 | Activation of Malassezia globosa beta-carbonic anhydrase incubated for 15 mins prior to testing by stopped flow CO2 hydrase method | 2016 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 26, Issue:5
| Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids. |
| AID1815482 | Activation of human carbonic anhydrase 9 by stopped flow assay | 2021 | European journal of medicinal chemistry, Dec-15, Volume: 226 | Binding site comparison for coumarin inhibitors and amine/amino acid activators of human carbonic anhydrases. |
| AID462830 | Activation of human recombinant CA2by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID691715 | Activity of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant CA expressed in Escherichia coli BL21(DE3) after 15 mins by phenol red staining based stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 22, Issue:20
| The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines. |
| AID462827 | Activity of human full length CA6 at 10 uM by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines. |
| AID291063 | Activation of human recombinant CA2 by CO2 hydrase assay | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15
| Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines. |
| AID387537 | Activation of human recombinant CA12 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID387528 | Activation of human recombinant CA2 after 24 hrs by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID1397319 | Activation of human CA1 by stopped-flow CO2 hydration assay | | | |
| AID387531 | Activation of human recombinant CA4 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID305776 | Activation of human recombinant carbonic anhydrase 5A by stopped-flow CO2 hydrase method | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5
| Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines. |
| AID1397322 | Activation of Trypanosoma cruzi CA preincubated for 15 mins followed by CO2 addition by stopped-flow assay | | | |
| AID387526 | Activation of human recombinant CA1 after 15 mins by stopped-flow CO2 hydration assay | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV. |
| AID375787 | Activation of membrane associated mouse recombinant carbonic anhydrase 15 isoform by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines. |
| AID725228 | Activation of human recombinant CA1 by stopped flow CO2 hydrase method | 2013 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 23, Issue:4
| The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines. |
| AID1397321 | Activation of Leishmania donovani chagasi CA preincubated for 15 mins followed by CO2 addition by stopped-flow assay | | | |
| AID414331 | Activation of yeast recombinant CA by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 19, Issue:6
| Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids. |
| AID375786 | Activation of human recombinant carbonic anhydrase 4 lacking 20 amino terminal residues by stopped-flow CO2 hydrase method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |