Page last updated: 2024-12-11

allolactose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID6454902
CHEMBL ID4876675
CHEBI ID36229
SCHEMBL ID154138
MeSH IDM0042396

Synonyms (19)

Synonym
beta-d-galp-(1->6)-d-glcp
beta-d-galacto-hexopyranosyl-(1->6)-d-gluco-hexopyranose
6-o-beta-d-galactopyranosyl-d-glucopyranose
CHEBI:36229
645-03-4
wurcs=2.0/2,2,1/[a2122h-1x_1-5][a2112h-1b_1-5]/1-2/a6-b1
gal(b1-6)glc
ALLOLACTOSE ,
beta-d-galactopyranosyl-(1->6)-d-glucopyranose
DB04116
(3r,4s,5s,6r)-6-[[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol
d-glucopyranose, 6-o-beta-d-galactopyranosyl- (van)
S11544
SCHEMBL154138
DTXSID80893952
Q3560955
6-o-|a-d-galactopyranosyl-d-glucopyranose
CHEMBL4876675 ,
bdbm50572954
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
glycosylglucose
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (11)

Processvia Protein(s)Taxonomy
positive regulation of dendritic cell differentiationGalectin-1Homo sapiens (human)
plasma cell differentiationGalectin-1Homo sapiens (human)
apoptotic processGalectin-1Homo sapiens (human)
T cell costimulationGalectin-1Homo sapiens (human)
regulation of apoptotic processGalectin-1Homo sapiens (human)
positive regulation of apoptotic processGalectin-1Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transductionGalectin-1Homo sapiens (human)
myoblast differentiationGalectin-1Homo sapiens (human)
positive regulation of viral entry into host cellGalectin-1Homo sapiens (human)
positive regulation of inflammatory responseGalectin-1Homo sapiens (human)
cell-cell adhesionGalectin-1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (4)

Processvia Protein(s)Taxonomy
RNA bindingGalectin-1Homo sapiens (human)
protein bindingGalectin-1Homo sapiens (human)
laminin bindingGalectin-1Homo sapiens (human)
lactose bindingGalectin-1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (8)

Processvia Protein(s)Taxonomy
collagen-containing extracellular matrixGalectin-1Homo sapiens (human)
extracellular regionGalectin-1Homo sapiens (human)
extracellular spaceGalectin-1Homo sapiens (human)
cytoplasmGalectin-1Homo sapiens (human)
endoplasmic reticulum lumenGalectin-1Homo sapiens (human)
cytosolGalectin-1Homo sapiens (human)
collagen-containing extracellular matrixGalectin-1Homo sapiens (human)
extracellular exosomeGalectin-1Homo sapiens (human)
galectin complexGalectin-1Homo sapiens (human)
extracellular spaceGalectin-1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1768541Binding affinity to human Gal-1 assessed as change in entropy by isothermal titration calorimetry2021Bioorganic & medicinal chemistry, 08-15, Volume: 44Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
AID1768540Binding affinity to human Gal-1 assessed as change in enthalpy by isothermal titration calorimetry2021Bioorganic & medicinal chemistry, 08-15, Volume: 44Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
AID1768542Binding affinity to human Gal-1 assessed as Gibbs free energy change by isothermal titration calorimetry2021Bioorganic & medicinal chemistry, 08-15, Volume: 44Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
AID1768539Binding affinity to human Gal-1 assessed as dissociation constant by isothermal titration calorimetry2021Bioorganic & medicinal chemistry, 08-15, Volume: 44Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
AID1768537Binding affinity to human Gal-1 assessed as inhibition of Gal-1 binding to immobilized asialofetuin pretreated with Gal-1 for 2 hrs followed by incubation with asialofetuin for 2 hrs by competitive solid phase assay2021Bioorganic & medicinal chemistry, 08-15, Volume: 44Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (38.89)18.7374
1990's1 (5.56)18.2507
2000's2 (11.11)29.6817
2010's7 (38.89)24.3611
2020's1 (5.56)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 53.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index53.15 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index5.04 (4.65)
Search Engine Demand Index79.78 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (53.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.56%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (94.44%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]