| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID497869 | Inhibition of TNF-alpha-induced NF-kappaB activation expressed in FADD deficient human Jurkat cells at 30 uM by luciferase reporter gene assay | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497862 | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in FADD deficient human Jurkat cells at 10 to 30 uM | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497866 | Inhibition of to HSP90 in FADD deficient human Jurkat cells assessed as RIP protein degradation at 30 uM by Western blot | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497854 | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in Sf9 cells | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497853 | Inhibition of cellular necroptosis in TNFalpha treated FADD deficient human Jurkat cells | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497868 | Inhibition of TNF-alpha-induced NF-kappaB activation expressed in HEK293T cells at 30 uM by luciferase reporter gene assay | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID497865 | Inhibition of FITC-geldanamycin binding to HSP90 in human Jurkat cell lysates at 30 uM by fluorimetric assay | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| AID306286 | Inhibition of TNF-alpha-induced necroptosis in FADD-deficient Jurkat T cells | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5
| Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5. |
| AID497851 | Inhibition of human RIP1 K45M mutant autophosphorylation expressed in HEK293T cells | 2008 | Nature chemical biology, May, Volume: 4, Issue:5
| Identification of RIP1 kinase as a specific cellular target of necrostatins. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |