yemuoside YM(10): from Stauntonia chinensis Decne; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Stauntonia | genus | [no description available] | Lardizabalaceae | [no description available] |
| Stauntonia chinensis | species | [no description available] | Lardizabalaceae | [no description available] |
| ID Source | ID |
|---|---|
| PubMed CID | 195123 |
| CHEMBL ID | 3890430 |
| SCHEMBL ID | 17187835 |
| MeSH ID | M0172763 |
| Synonym |
|---|
| yemuoside ym(10) |
| ciwujianoside-b |
| 28-o-rhamnopyranosyl-(1-4)-glucopyranosyl-(1-6)-glucopyranosyl 3-o-rhamnosyl-(1-2)-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid |
| 30-noroleana-12,20(29)-dien-28-oic acid, 3-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl)oxy)-, o-6-deoxy-alpha-l-mannopyranosyl-(1-4)-o-beta-d-glucopyranosyl-(1-6)-beta-d-glucopyranosyl ester, (3beta)- |
| yemuoside ym10 |
| acanthopanax senticosides b |
| Q-100073 |
| SCHEMBL17187835 |
| bdbm50253018 |
| yemuoside ym |
| CHEMBL3890430 , |
| HY-N0307 |
| CS-0008805 |
| ciwujianoside b; acanthopanax senticosides b |
| MS-32037 |
| AKOS040753101 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 (µMol) | 97.3000 | 0.0013 | 2.8138 | 9.8200 | AID1453375 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| xanthine dehydrogenase activity | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| xanthine oxidase activity | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| iron ion binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| protein binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| protein homodimerization activity | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| molybdopterin cofactor binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| flavin adenine dinucleotide binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| 2 iron, 2 sulfur cluster binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| hypoxanthine dehydrogenase activity | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| hypoxanthine oxidase activity | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| FAD binding | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| cytosol | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| extracellular space | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| peroxisome | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| cytosol | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| sarcoplasmic reticulum | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| extracellular space | Xanthine dehydrogenase/oxidase | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1323390 | Inhibition of amyloid beta (25 to 35)-induced neuronal degeneration in ddY mouse embryo cortical neurons assessed as restoration of axonal outgrowth by measuring length of phosphorylated neurofilament-H-positive neurites at 10 uM treated 3 days post amylo | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Effects of Oleanane-Type Triterpene Saponins from the Leaves of Eleutherococcus senticosus in an Axonal Outgrowth Assay. |
| AID1453375 | Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition by spectrophotometric method | 2017 | Bioorganic & medicinal chemistry, 07-01, Volume: 25, Issue:13 | Potential anti-gout constituents as xanthine oxidase inhibitor from the fruits of Stauntonia brachyanthera. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.53) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||