2-(4-fluorophenyl)-1,2-benzothiazol-3-one profile

ID Source	ID
PubMed CID	22416276
CHEMBL ID	1520143
CHEBI ID	92126
SCHEMBL ID	1894451

Synonym
MLS-0390876.0002
MLS-0390876.0001 ,
MLS002460498
smr001382703
SCHEMBL1894451
HMS2204O03
HMS3335M01
2-(4-fluorophenyl)-1,2-benzothiazol-3-one
bdbm46079
cid_22416276
CHEMBL1520143
CHEBI:92126
Q27163911

Class	Description
benzothiazoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	12.5893	0.6310	35.7641	100.0000	AID504339
Luciferase	Photinus pyralis (common eastern firefly)	Potency	17.7828	0.0072	15.7588	89.3584	AID588342
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	50.1187	0.1000	20.8793	79.4328	AID588453
GLS protein	Homo sapiens (human)	Potency	10.0000	0.3548	7.9355	39.8107	AID624170
TDP1 protein	Homo sapiens (human)	Potency	3.4635	0.0008	11.3822	44.6684	AID686978; AID686979
Smad3	Homo sapiens (human)	Potency	10.0000	0.0052	7.8098	29.0929	AID588855
hypothetical protein, conserved	Trypanosoma brucei	Potency	8.9125	0.2239	11.2451	35.4813	AID624173
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	4.4668	0.7079	36.9043	89.1251	AID504333
P53	Homo sapiens (human)	Potency	35.4813	0.0731	9.6858	31.6228	AID504706
IDH1	Homo sapiens (human)	Potency	18.3564	0.0052	10.8652	35.4813	AID686970
vitamin D3 receptor isoform VDRA	Homo sapiens (human)	Potency	15.8489	0.3548	28.0659	89.1251	AID504847
flap endonuclease 1	Homo sapiens (human)	Potency	79.4328	0.1337	25.4129	89.1251	AID588795
ras-related protein Rab-9A	Homo sapiens (human)	Potency	3.5481	0.0002	2.6215	31.4954	AID485297
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	2.9935	0.1683	16.4040	67.0158	AID720504
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	39.8107	0.0501	27.0736	89.1251	AID588590
urokinase-type plasminogen activator precursor	Mus musculus (house mouse)	Potency	4.4668	0.1585	5.2879	12.5893	AID540303
plasminogen precursor	Mus musculus (house mouse)	Potency	4.4668	0.1585	5.2879	12.5893	AID540303
urokinase plasminogen activator surface receptor precursor	Mus musculus (house mouse)	Potency	4.4668	0.1585	5.2879	12.5893	AID540303
geminin	Homo sapiens (human)	Potency	16.6012	0.0046	11.3741	33.4983	AID624296; AID624297
Vpr	Human immunodeficiency virus 1	Potency	5.6234	1.5849	19.6264	63.0957	AID651644
histone acetyltransferase KAT2A isoform 1	Homo sapiens (human)	Potency	1.9953	0.2512	15.8432	39.8107	AID504327
Rap guanine nucleotide exchange factor 3	Homo sapiens (human)	Potency	22.3872	6.3096	60.2008	112.2020	AID720709
Alpha-synuclein	Homo sapiens (human)	Potency	35.4813	0.5623	9.3985	25.1189	AID652106
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	15.8489	1.7783	16.2081	35.4813	AID652104
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	12.3561	0.0601	10.7453	37.9330	AID485367; AID504637
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
MPI protein	Homo sapiens (human)	IC50 (µMol)	1.4900	0.1900	13.8256	50.1000	AID1535
caspase recruitment domain family, member 15	Homo sapiens (human)	IC50 (µMol)	5.1020	0.6215	4.0504	6.6330	AID651553
phosphomannomutase 2	Homo sapiens (human)	IC50 (µMol)	18.1000	0.6720	34.7838	97.3000	AID1655
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	Homo sapiens (human)	IC50 (µMol)	100.0000	0.1250	16.2603	74.8000	AID1056
rac GTPase-activating protein 1 isoform a	Homo sapiens (human)	IC50 (µMol)	4.8080	0.6902	0.8145	0.9388	AID652153
phosphoethanolamine/phosphocholine phosphatase isoform 1	Homo sapiens (human)	IC50 (µMol)	4.8500	0.1110	0.5769	0.9410	AID1666
polyadenylate-binding protein 1	Homo sapiens (human)	IC50 (µMol)	66.0000	4.9100	23.7029	76.1900	AID602259; AID602260
receptor-interacting serine/threonine-protein kinase 2 isoform 1	Homo sapiens (human)	IC50 (µMol)	5.1020	0.6215	4.0504	6.6330	AID651553
rac GTPase-activating protein 1 isoform a	Homo sapiens (human)	IC50 (µMol)	39.2700	7.3900	57.8904	301.2400	AID624330
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)	IC50 (µMol)	12.4000	0.2700	26.3638	100.0000	AID504719
DNA dC->dU-editing enzyme APOBEC-3A isoform a	Homo sapiens (human)	IC50 (µMol)	100.0000	1.4800	14.5267	61.2000	AID504722
Phosphomannomutase 2	Homo sapiens (human)	IC50 (µMol)	20.0000	5.2000	5.2000	5.2000	AID1187643
Mannose-6-phosphate isomerase	Homo sapiens (human)	IC50 (µMol)	3.4000	0.7100	3.3175	6.4000	AID1187642
Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)	IC50 (µMol)	4.9000	0.5000	2.1343	5.2000	AID1187641
Beta lactamase (plasmid)	Pseudomonas aeruginosa	IC50 (µMol)	29.5230	0.7091	5.0549	7.7510	AID651552
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
MSRA protein	Bos taurus (cattle)	EC50 (µMol)	98.5060	3.6370	4.0500	4.4630	AID623963
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
protein glycosylation	Phosphomannomutase 2	Homo sapiens (human)
GDP-mannose biosynthetic process	Phosphomannomutase 2	Homo sapiens (human)
protein N-linked glycosylation	Phosphomannomutase 2	Homo sapiens (human)
mannose metabolic process	Phosphomannomutase 2	Homo sapiens (human)
angiogenesis	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
adaptive immune response	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
signal transduction	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
associative learning	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
Rap protein signal transduction	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
regulation of actin cytoskeleton organization	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
negative regulation of syncytium formation by plasma membrane fusion	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
intracellular signal transduction	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
positive regulation of GTPase activity	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
regulation of angiogenesis	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
positive regulation of angiogenesis	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
positive regulation of protein export from nucleus	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
positive regulation of stress fiber assembly	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
positive regulation of syncytium formation by plasma membrane fusion	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
establishment of endothelial barrier	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
cellular response to cAMP	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
Ras protein signal transduction	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
regulation of insulin secretion	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
GDP-mannose biosynthetic process	Mannose-6-phosphate isomerase	Homo sapiens (human)
mannose to fructose-6-phosphate catabolic process	Mannose-6-phosphate isomerase	Homo sapiens (human)
calcium ion homeostasis	Alpha-synuclein	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Alpha-synuclein	Homo sapiens (human)
microglial cell activation	Alpha-synuclein	Homo sapiens (human)
positive regulation of receptor recycling	Alpha-synuclein	Homo sapiens (human)
positive regulation of neurotransmitter secretion	Alpha-synuclein	Homo sapiens (human)
negative regulation of protein kinase activity	Alpha-synuclein	Homo sapiens (human)
fatty acid metabolic process	Alpha-synuclein	Homo sapiens (human)
neutral lipid metabolic process	Alpha-synuclein	Homo sapiens (human)
phospholipid metabolic process	Alpha-synuclein	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Alpha-synuclein	Homo sapiens (human)
mitochondrial membrane organization	Alpha-synuclein	Homo sapiens (human)
adult locomotory behavior	Alpha-synuclein	Homo sapiens (human)
response to xenobiotic stimulus	Alpha-synuclein	Homo sapiens (human)
response to iron(II) ion	Alpha-synuclein	Homo sapiens (human)
regulation of phospholipase activity	Alpha-synuclein	Homo sapiens (human)
negative regulation of platelet-derived growth factor receptor signaling pathway	Alpha-synuclein	Homo sapiens (human)
regulation of glutamate secretion	Alpha-synuclein	Homo sapiens (human)
regulation of dopamine secretion	Alpha-synuclein	Homo sapiens (human)
synaptic vesicle exocytosis	Alpha-synuclein	Homo sapiens (human)
synaptic vesicle priming	Alpha-synuclein	Homo sapiens (human)
regulation of transmembrane transporter activity	Alpha-synuclein	Homo sapiens (human)
negative regulation of microtubule polymerization	Alpha-synuclein	Homo sapiens (human)
receptor internalization	Alpha-synuclein	Homo sapiens (human)
protein destabilization	Alpha-synuclein	Homo sapiens (human)
response to magnesium ion	Alpha-synuclein	Homo sapiens (human)
negative regulation of transporter activity	Alpha-synuclein	Homo sapiens (human)
response to lipopolysaccharide	Alpha-synuclein	Homo sapiens (human)
negative regulation of monooxygenase activity	Alpha-synuclein	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Alpha-synuclein	Homo sapiens (human)
response to type II interferon	Alpha-synuclein	Homo sapiens (human)
cellular response to oxidative stress	Alpha-synuclein	Homo sapiens (human)
SNARE complex assembly	Alpha-synuclein	Homo sapiens (human)
positive regulation of SNARE complex assembly	Alpha-synuclein	Homo sapiens (human)
regulation of locomotion	Alpha-synuclein	Homo sapiens (human)
dopamine biosynthetic process	Alpha-synuclein	Homo sapiens (human)
mitochondrial ATP synthesis coupled electron transport	Alpha-synuclein	Homo sapiens (human)
regulation of macrophage activation	Alpha-synuclein	Homo sapiens (human)
positive regulation of apoptotic process	Alpha-synuclein	Homo sapiens (human)
negative regulation of apoptotic process	Alpha-synuclein	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Alpha-synuclein	Homo sapiens (human)
negative regulation of neuron apoptotic process	Alpha-synuclein	Homo sapiens (human)
positive regulation of endocytosis	Alpha-synuclein	Homo sapiens (human)
negative regulation of exocytosis	Alpha-synuclein	Homo sapiens (human)
positive regulation of exocytosis	Alpha-synuclein	Homo sapiens (human)
regulation of long-term neuronal synaptic plasticity	Alpha-synuclein	Homo sapiens (human)
synaptic vesicle endocytosis	Alpha-synuclein	Homo sapiens (human)
synaptic vesicle transport	Alpha-synuclein	Homo sapiens (human)
positive regulation of inflammatory response	Alpha-synuclein	Homo sapiens (human)
regulation of acyl-CoA biosynthetic process	Alpha-synuclein	Homo sapiens (human)
protein tetramerization	Alpha-synuclein	Homo sapiens (human)
positive regulation of release of sequestered calcium ion into cytosol	Alpha-synuclein	Homo sapiens (human)
neuron apoptotic process	Alpha-synuclein	Homo sapiens (human)
dopamine uptake involved in synaptic transmission	Alpha-synuclein	Homo sapiens (human)
negative regulation of dopamine uptake involved in synaptic transmission	Alpha-synuclein	Homo sapiens (human)
negative regulation of serotonin uptake	Alpha-synuclein	Homo sapiens (human)
regulation of norepinephrine uptake	Alpha-synuclein	Homo sapiens (human)
negative regulation of norepinephrine uptake	Alpha-synuclein	Homo sapiens (human)
excitatory postsynaptic potential	Alpha-synuclein	Homo sapiens (human)
long-term synaptic potentiation	Alpha-synuclein	Homo sapiens (human)
positive regulation of inositol phosphate biosynthetic process	Alpha-synuclein	Homo sapiens (human)
negative regulation of thrombin-activated receptor signaling pathway	Alpha-synuclein	Homo sapiens (human)
response to interleukin-1	Alpha-synuclein	Homo sapiens (human)
cellular response to copper ion	Alpha-synuclein	Homo sapiens (human)
cellular response to epinephrine stimulus	Alpha-synuclein	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Alpha-synuclein	Homo sapiens (human)
supramolecular fiber organization	Alpha-synuclein	Homo sapiens (human)
negative regulation of mitochondrial electron transport, NADH to ubiquinone	Alpha-synuclein	Homo sapiens (human)
positive regulation of glutathione peroxidase activity	Alpha-synuclein	Homo sapiens (human)
positive regulation of hydrogen peroxide catabolic process	Alpha-synuclein	Homo sapiens (human)
regulation of synaptic vesicle recycling	Alpha-synuclein	Homo sapiens (human)
regulation of reactive oxygen species biosynthetic process	Alpha-synuclein	Homo sapiens (human)
positive regulation of protein localization to cell periphery	Alpha-synuclein	Homo sapiens (human)
negative regulation of chaperone-mediated autophagy	Alpha-synuclein	Homo sapiens (human)
regulation of presynapse assembly	Alpha-synuclein	Homo sapiens (human)
amyloid fibril formation	Alpha-synuclein	Homo sapiens (human)
synapse organization	Alpha-synuclein	Homo sapiens (human)
chemical synaptic transmission	Alpha-synuclein	Homo sapiens (human)
negative regulation of protein phosphorylation	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA processing	TAR DNA-binding protein 43	Homo sapiens (human)
RNA splicing	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of protein stability	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of insulin secretion	TAR DNA-binding protein 43	Homo sapiens (human)
response to endoplasmic reticulum stress	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of protein import into nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of circadian rhythm	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of apoptotic process	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation by host of viral transcription	TAR DNA-binding protein 43	Homo sapiens (human)
rhythmic process	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of cell cycle	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA destabilization	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear inner membrane organization	TAR DNA-binding protein 43	Homo sapiens (human)
amyloid fibril formation	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
endochondral ossification	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
bone mineralization	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
regulation of bone mineralization	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
bone mineralization involved in bone maturation	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
phosphomannomutase activity	Phosphomannomutase 2	Homo sapiens (human)
protein binding	Phosphomannomutase 2	Homo sapiens (human)
metal ion binding	Phosphomannomutase 2	Homo sapiens (human)
guanyl-nucleotide exchange factor activity	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
protein binding	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
protein domain specific binding	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
cAMP binding	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
mannose-6-phosphate isomerase activity	Mannose-6-phosphate isomerase	Homo sapiens (human)
zinc ion binding	Mannose-6-phosphate isomerase	Homo sapiens (human)
fatty acid binding	Alpha-synuclein	Homo sapiens (human)
phospholipase D inhibitor activity	Alpha-synuclein	Homo sapiens (human)
SNARE binding	Alpha-synuclein	Homo sapiens (human)
magnesium ion binding	Alpha-synuclein	Homo sapiens (human)
transcription cis-regulatory region binding	Alpha-synuclein	Homo sapiens (human)
actin binding	Alpha-synuclein	Homo sapiens (human)
protein kinase inhibitor activity	Alpha-synuclein	Homo sapiens (human)
copper ion binding	Alpha-synuclein	Homo sapiens (human)
calcium ion binding	Alpha-synuclein	Homo sapiens (human)
protein binding	Alpha-synuclein	Homo sapiens (human)
phospholipid binding	Alpha-synuclein	Homo sapiens (human)
ferrous iron binding	Alpha-synuclein	Homo sapiens (human)
zinc ion binding	Alpha-synuclein	Homo sapiens (human)
lipid binding	Alpha-synuclein	Homo sapiens (human)
oxidoreductase activity	Alpha-synuclein	Homo sapiens (human)
kinesin binding	Alpha-synuclein	Homo sapiens (human)
Hsp70 protein binding	Alpha-synuclein	Homo sapiens (human)
histone binding	Alpha-synuclein	Homo sapiens (human)
identical protein binding	Alpha-synuclein	Homo sapiens (human)
alpha-tubulin binding	Alpha-synuclein	Homo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Alpha-synuclein	Homo sapiens (human)
tau protein binding	Alpha-synuclein	Homo sapiens (human)
phosphoprotein binding	Alpha-synuclein	Homo sapiens (human)
molecular adaptor activity	Alpha-synuclein	Homo sapiens (human)
dynein complex binding	Alpha-synuclein	Homo sapiens (human)
cuprous ion binding	Alpha-synuclein	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
double-stranded DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
RNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA 3'-UTR binding	TAR DNA-binding protein 43	Homo sapiens (human)
protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
lipid binding	TAR DNA-binding protein 43	Homo sapiens (human)
identical protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
pre-mRNA intronic binding	TAR DNA-binding protein 43	Homo sapiens (human)
molecular condensate scaffold activity	TAR DNA-binding protein 43	Homo sapiens (human)
protein binding	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
pyrophosphatase activity	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
metal ion binding	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
phosphocholine phosphatase activity	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
phosphoethanolamine phosphatase activity	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
phosphatase activity	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
nucleoplasm	Phosphomannomutase 2	Homo sapiens (human)
cytosol	Phosphomannomutase 2	Homo sapiens (human)
neuronal cell body	Phosphomannomutase 2	Homo sapiens (human)
cytosol	Phosphomannomutase 2	Homo sapiens (human)
plasma membrane	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
cortical actin cytoskeleton	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
plasma membrane	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
microvillus	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
endomembrane system	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
membrane	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
lamellipodium	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
filopodium	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
extracellular exosome	Rap guanine nucleotide exchange factor 3	Homo sapiens (human)
cytosol	Mannose-6-phosphate isomerase	Homo sapiens (human)
extracellular exosome	Mannose-6-phosphate isomerase	Homo sapiens (human)
cytosol	Mannose-6-phosphate isomerase	Homo sapiens (human)
platelet alpha granule membrane	Alpha-synuclein	Homo sapiens (human)
extracellular region	Alpha-synuclein	Homo sapiens (human)
extracellular space	Alpha-synuclein	Homo sapiens (human)
nucleus	Alpha-synuclein	Homo sapiens (human)
cytoplasm	Alpha-synuclein	Homo sapiens (human)
mitochondrion	Alpha-synuclein	Homo sapiens (human)
lysosome	Alpha-synuclein	Homo sapiens (human)
cytosol	Alpha-synuclein	Homo sapiens (human)
plasma membrane	Alpha-synuclein	Homo sapiens (human)
cell cortex	Alpha-synuclein	Homo sapiens (human)
actin cytoskeleton	Alpha-synuclein	Homo sapiens (human)
membrane	Alpha-synuclein	Homo sapiens (human)
inclusion body	Alpha-synuclein	Homo sapiens (human)
axon	Alpha-synuclein	Homo sapiens (human)
growth cone	Alpha-synuclein	Homo sapiens (human)
synaptic vesicle membrane	Alpha-synuclein	Homo sapiens (human)
perinuclear region of cytoplasm	Alpha-synuclein	Homo sapiens (human)
postsynapse	Alpha-synuclein	Homo sapiens (human)
supramolecular fiber	Alpha-synuclein	Homo sapiens (human)
protein-containing complex	Alpha-synuclein	Homo sapiens (human)
cytoplasm	Alpha-synuclein	Homo sapiens (human)
axon terminus	Alpha-synuclein	Homo sapiens (human)
neuronal cell body	Alpha-synuclein	Homo sapiens (human)
intracellular non-membrane-bounded organelle	TAR DNA-binding protein 43	Homo sapiens (human)
nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
perichromatin fibrils	TAR DNA-binding protein 43	Homo sapiens (human)
mitochondrion	TAR DNA-binding protein 43	Homo sapiens (human)
cytoplasmic stress granule	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear speck	TAR DNA-binding protein 43	Homo sapiens (human)
interchromatin granule	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
chromatin	TAR DNA-binding protein 43	Homo sapiens (human)
extracellular membrane-bounded organelle	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
cytosol	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
extracellular matrix	Phosphoethanolamine/phosphocholine phosphatase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (68)

Assay ID	Title	Year	Journal	Article
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1324725	Antibacterial activity against methicillin-resistant Staphylococcus aureus 2 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430060	Selectivity index, ratio of CC50 for monkey Vero C1008 cells to IC50 for chloroquine-sensitive Plasmodium falciparum 3D7
AID1324750	Antibacterial activity against Enterococcus faecalis ATCC 49533 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430053	Anti-fungal activity against Sporothrix schenckii after 48 hrs by broth microdilution method
AID1430047	Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method
AID1430051	Anti-fungal activity against Candida albicans after 48 hrs by broth microdilution method
AID1324744	Antibacterial activity against methicillin-resistant Staphylococcus aureus USA100 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324732	Antibacterial activity against methicillin-resistant Staphylococcus aureus C19 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430046	Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700699 by broth microdilution method
AID1324748	Antibacterial activity against Staphylococcus epidermidis ATCC 35984 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324733	Antibacterial activity against methicillin-resistant Staphylococcus aureus G1 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324742	Antibacterial activity against methicillin-resistant Staphylococcus aureus S22 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430057	Antibacterial activity against gentamicin-resistant Staphylococcus aureus ATCC 33592 by broth microdilution method
AID1324739	Antibacterial activity against methicillin-resistant Staphylococcus aureus NRS77 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430059	Cytotoxicity against monkey Vero C1008 cells after 72 hrs by MTT assay
AID1324730	Antibacterial activity against methicillin-resistant Staphylococcus aureus C14 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324738	Antibacterial activity against methicillin-resistant Staphylococcus aureus NRS51 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324746	Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430049	Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 by broth microdilution method
AID1324740	Antibacterial activity against methicillin-resistant Staphylococcus aureus S14 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324749	Antibacterial activity against Enterococcus faecalis ATCC 29212 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324724	Antibacterial activity against methicillin-resistant Staphylococcus aureus 1 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324731	Antibacterial activity against methicillin-resistant Staphylococcus aureus C16 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324720	Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 6538 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1187642	Inhibition of phosphomannose isomerase (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17	Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
AID1430052	Anti-fungal activity against Cryptococcus neoformans after 48 hrs by broth microdilution method
AID1430050	Antibacterial activity against Klebsiella pneumoniae ATCC 27736 by broth microdilution method
AID1324754	Antibacterial activity against Mycobacterium smegmatis MC2-155 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430058	Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 after 72 hrs by SYBR Green-1 staining based fluorescence assay
AID1430048	Antibacterial activity against Escherichia coli ATCC 9637 by broth microdilution method
AID1187641	Inhibition of PHOSPHO1 phosphoethanolamine activity (unknown origin) assessed as amount of inorganic phosphate release after 30 mins	2014	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17	Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
AID1430045	Antibacterial activity against Staphylococcus aureus ATCC 25923 by broth microdilution method
AID1430055	Anti-fungal activity against Aspergillus fumigatus after 48 hrs by broth microdilution method
AID1324737	Antibacterial activity against methicillin-resistant Staphylococcus aureus NRS4 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324727	Antibacterial activity against methicillin-resistant Staphylococcus aureus C1 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324752	Antibacterial activity against Vancomycin-resistant Enterococcus measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324753	Antibacterial activity against Listeria monocytogenes ATCC 19115 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1430056	Anti-fungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by broth microdilution method
AID1324721	Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324745	Antibacterial activity against methicillin-resistant Staphylococcus aureus USA200 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324722	Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324751	Antibacterial activity against Enterococcus faecium BM4105-RF measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324723	Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324729	Antibacterial activity against methicillin-resistant Staphylococcus aureus C7 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324741	Antibacterial activity against methicillin-resistant Staphylococcus aureus S17 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324736	Antibacterial activity against methicillin-resistant Staphylococcus aureus G14 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324743	Antibacterial activity against methicillin-resistant Staphylococcus aureus S24 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1187643	Inhibition of PMM2 (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17	Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
AID1430054	Anti-fungal activity against Trichophyton mentagrophytes after 48 hrs by broth microdilution method
AID1324771	Antibiofilm activity against methicillin-sensitive Staphylococcus aureus ATCC 6538 assessed as reduction of biofilm at 62..5 ug/ml measured after 24 hrs by crystal violet staining based method relative to control	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324747	Antibacterial activity against methicillin-resistant Staphylococcus aureus USA600 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324735	Antibacterial activity against methicillin-resistant Staphylococcus aureus G12 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324726	Antibacterial activity against methicillin-resistant Staphylococcus aureus BRS3 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324734	Antibacterial activity against methicillin-resistant Staphylococcus aureus G6 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
AID1324728	Antibacterial activity against methicillin-resistant Staphylococcus aureus C2 measured after overnight incubation by broth double-dilution method	2016	Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24	Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (12.50)	29.6817
2010's	6 (75.00)	24.3611
2020's	1 (12.50)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ebselen ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.	2.13	1	benzoselenazole	anti-inflammatory drug; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 3.5.4.1 (cytosine deaminase) inhibitor; EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor; enzyme mimic; ferroptosis inhibitor; genotoxin; hepatoprotective agent; neuroprotective agent; radical scavenger
amikacin Amikacin: A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.. amikacin : An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.	2.13	1	alpha-D-glucoside; amino cyclitol glycoside; aminoglycoside; carboxamide	antibacterial drug; antimicrobial agent; nephrotoxin
2-phenyl-1,2-benzisothiazol-3-(2h)-one 2-phenyl-1,2-benzisothiazol-3-(2H)-one: structure given in first source; sulfur analog of ebselen	2.52	2
6-fluoro-2-phenyl-1,2-benzothiazol-3-one [no description available]	2.1	1	benzothiazoles
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one [no description available]	2.1	1	sulfonamide
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acid [no description available]	2.1	1	sulfonamide
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide [no description available]	2.1	1	sulfonamide
2-(4-chlorophenyl)-1,2-benzothiazol-3-one [no description available]	2.13	1	benzothiazoles
2-(3-chlorophenyl)-1,2-benzothiazol-3-one [no description available]	2.1	1	benzothiazoles

Condition	Indicated	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	0	2.05	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	2.05	1	0

2-(4-fluorophenyl)-1,2-benzothiazol-3-one

Cross-References

Synonyms (13)

Drug Classes (1)

Protein Targets (43)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (123)

Molecular Functions (43)

Ceullar Components (37)

Bioassays (68)

Research

Studies (8)

Market Indicators

Research Demand Index: 12.17

Study Types

2-(4-fluorophenyl)-1,2-benzothiazol-3-one

Cross-References

Synonyms (13)

Drug Classes (1)

Protein Targets (43)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (123)

Molecular Functions (43)

Ceullar Components (37)

Bioassays (68)

Research

Studies (8)

Market Indicators

Research Demand Index: 12.17

Study Types

Related Drugs (9)

Related Conditions (2)