Page last updated: 2024-08-24

carbenoxolone sodium and cortisone

carbenoxolone sodium has been researched along with cortisone in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's18 (60.00)18.2507
2000's8 (26.67)29.6817
2010's2 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stokes, GS1
Auden, RR; Barrowman, JA1
Connacher, AA; Edwards, CR; Walker, BR; Webb, DJ1
Baker, ME; Duax, WL; Erman, M; Ghosh, D; Pangborn, W1
Edwards, CR; Stewart, PM2
Schleimer, RP1
Govindan, MV; Pagé, N; Warriar, N2
Yang, K; Yu, M1
Stewart, PM; Walker, BR; Whorwood, CB1
Morris, DJ; Myles, K; Souness, GW1
Hanukoglu, A; Rösler, A; Ulick, S; Wang, JZ1
Edwards, CR; Padfield, PL; Shackleton, CH; Stewart, PM; Walker, BR1
Gao, HB; Ge, RS; Gunsalus, GL; Hardy, MP; Nacharaju, VL1
Khalil, MW; Killinger, DW; Strutt, BJ; Yang, K1
Best, R; Walker, BR1
Eggo, MC; Hewison, M; Ricketts, ML; Shoesmith, KJ; Stewart, PM; Strain, A1
Bellows, CG; Ciaccia, A; Heersche, JN1
Michael, AE; Norgate, DP; Sewell, KJ; Shirley, DG; Thompson, A; Unwin, RJ1
Hewison, M; Murray, PI; Rauz, S; Shackleton, CH; Stewart, PM; Walker, EA1
Andrew, R; Jones, GC; Smith, K; Walker, BR1
Cheung, CM; Coca-Prados, M; Murray, PI; Rauz, S; Stewart, PM; Walker, EA; Wood, PJ1
Andrew, R; Andrews, RC; Homer, NZ; Sandeep, TC; Smith, K; Walker, BR1
Abdallah, BM; Beck-Nielsen, H; Gaster, M1
Busby, J; Castro, VM; Chen, M; Hale, C; Kim, KW; Nybo, R; Svensson, S; Tsuruda, T; Wang, M; Wang, Z; Xiong, F1
Bähr, V; Diederich, S; Jussli, J; Lepenies, J; Pfeiffer, AF; Quinkler, M1
Michael, AE; Sunak, N; Webb, RJ; Wren, L1
Grumbach, Y; Grunstein, JS; Grunstein, MM; Hu, A; Jiao, J; Josephson, MB; Kreiger, PA; McDonough, J; Nino, G; Paranjape, C; Xu, S1
Koyama, H; Matsumoto, H; Nakamura, Y; Okusa, T; Teshima, T1

Reviews

3 review(s) available for carbenoxolone sodium and cortisone

ArticleYear
Drug-induced hypertension: pathogenesis and management.
    Drugs, 1976, Volume: 12, Issue:3

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Antidepressive Agents, Tricyclic; Carbenoxolone; Clonidine; Contraceptives, Oral, Hormonal; Cortisone; Estrogens; Glycyrrhiza; Hemodynamics; Humans; Hypertension; Monoamine Oxidase Inhibitors; Plants, Medicinal; Progestins; Renin; Sodium; Sympathomimetics; Water

1976
The cortisol-cortisone shuttle and hypertension.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 40, Issue:4-6

    Topics: Animals; Carbenoxolone; Cortisone; Glycyrrhiza; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hypertension; Kidney; Mineralocorticoids; Plants, Medicinal; Water-Electrolyte Balance

1991
Steroid hormones and hypertension: the cortisol-cortisone shuttle.
    Steroids, 1993, Volume: 58, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cortisone; Glycyrrhiza; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hypertension; Metabolism, Inborn Errors; Mineralocorticoids; Plants, Medicinal; Receptors, Mineralocorticoid

1993

Trials

5 trial(s) available for carbenoxolone sodium and cortisone

ArticleYear
Glucocorticoids and blood pressure: a role for the cortisol/cortisone shuttle in the control of vascular tone in man.
    Clinical science (London, England : 1979), 1992, Volume: 83, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Blood Pressure; Carbenoxolone; Cortisone; Double-Blind Method; Female; Glucocorticoids; Glycyrrhiza; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Kidney; Male; Muscle, Smooth, Vascular; Norepinephrine; Plants, Medicinal; Skin; Vasoconstriction

1992
Additional value of measurement of urinary cortisone and unconjugated cortisol metabolites in assessing the activity of 11 beta-hydroxysteroid dehydrogenase in vivo.
    Clinical endocrinology, 1997, Volume: 47, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Anti-Inflammatory Agents; Carbenoxolone; Cortisone; Gas Chromatography-Mass Spectrometry; Glycyrrhetinic Acid; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Isoenzymes; Kidney; Male; Sensitivity and Specificity

1997
Distinguishing the activities of 11beta-hydroxysteroid dehydrogenases in vivo using isotopically labeled cortisol.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Carbenoxolone; Cortisone; Cross-Over Studies; Deuterium; Double-Blind Method; Enzyme Inhibitors; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Infusions, Intravenous; Isoenzymes; Kinetics; Male; Mass Spectrometry

2002
Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension.
    QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:7

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aged; Aqueous Humor; Carbenoxolone; Cortisone; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Intraocular Pressure; Male; Mineralocorticoid Receptor Antagonists; Ocular Hypertension; Prospective Studies; Receptors, Glucocorticoid

2003
Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.
    Diabetes, 2005, Volume: 54, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Adult; Carbenoxolone; Cortisone; Cross-Over Studies; Double-Blind Method; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Obesity

2005

Other Studies

22 other study(ies) available for carbenoxolone sodium and cortisone

ArticleYear
[The medical management of carcinoma of the stomach (author's transl)].
    Leber, Magen, Darm, 1976, Volume: 6, Issue:2

    Topics: Analgesics; Anemia; Antacids; Carbenoxolone; Cortisone; Dexamethasone; Diet Therapy; Fast Neutrons; Humans; Iron; Parasympatholytics; Stomach Neoplasms; Vitamin B 12

1976
Inhibition of Streptomyces hydrogenans 3 alpha,20 beta-hydroxysteroid dehydrogenase by licorice-derived compounds and crystallization of an enzyme-cofactor-inhibitor complex.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:8

    Topics: Binding Sites; Carbenoxolone; Coenzymes; Cortisone; Crystallization; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Hydroxysteroid Dehydrogenases; Kinetics; Macromolecular Substances; Plant Extracts; Plants, Medicinal; Progesterone; Streptomyces; X-Ray Diffraction

1992
The cortisol-cortisone shuttle and the apparent specificity of glucocorticoid and mineralocorticoid receptors.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:5B

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cortisone; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Immunohistochemistry; Kidney; Mineralocorticoids; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Recombinant Proteins; Substrate Specificity; Urinary Bladder

1991
Potential regulation of inflammation in the lung by local metabolism of hydrocortisone.
    American journal of respiratory cell and molecular biology, 1991, Volume: 4, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carbenoxolone; Cells, Cultured; Cortisone; Endothelium, Vascular; Epithelium; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Inflammation; Kinetics; Lung; Pleura; Trachea

1991
Transcription activation of mouse mammary tumor virus-chloramphenicol acetyltransferase: a model to study the metabolism of cortisol.
    Biochemistry, 1994, Nov-01, Volume: 33, Issue:43

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carbenoxolone; Cell Line; Chloramphenicol O-Acetyltransferase; Cortisone; Gene Expression Regulation; Genes, Reporter; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Mammary Tumor Virus, Mouse; NADP; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Recombinant Fusion Proteins; Transcription, Genetic; Transcriptional Activation; Transfection

1994
11 beta-Hydroxysteroid dehydrogenase and tissue specificity of androgen action in human prostate cancer cell LNCaP.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:2-3

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Acetylation; Aldosterone; Androgens; Carbenoxolone; Chloramphenicol O-Acetyltransferase; Cortisone; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Male; Mammary Tumor Virus, Mouse; NAD; Prostatic Neoplasms; Receptors, Mineralocorticoid; Transcription, Genetic; Transfection; Tritium; Tumor Cells, Cultured

1994
Evidence for distinct isoforms of 11 beta-hydroxysteroid dehydrogenase in the ovine liver and kidney.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:2-3

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cell Fractionation; Cortisone; Female; Hydrocortisone; Hydroxysteroid Dehydrogenases; Isoenzymes; Kidney; Kinetics; Liver; Microsomes; Microsomes, Liver; NAD; NADP; Pregnancy; Sheep

1994
Other physiological considerations of protective mechanisms of mineralocorticoid action.
    Steroids, 1994, Volume: 59, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Carbenoxolone; Corticosterone; Cortisone; Cortodoxone; Hydroxysteroid Dehydrogenases; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley

1994
The effect of carbenoxolone on the peripheral metabolism of cortisol in human patients.
    The Journal of laboratory and clinical medicine, 1993, Volume: 122, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carbenoxolone; Child; Cortisone; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Mineralocorticoids; Syndrome

1993
Deficient inactivation of cortisol by 11 beta-hydroxysteroid dehydrogenase in essential hypertension.
    Clinical endocrinology, 1993, Volume: 39, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Carbenoxolone; Cortisone; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hypertension; Kidney; Male; Potassium; Renin

1993
Identification of a kinetically distinct activity of 11beta-hydroxysteroid dehydrogenase in rat Leydig cells.
    Endocrinology, 1997, Volume: 138, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cortisone; Hydroxysteroid Dehydrogenases; Isoenzymes; Kinetics; Leydig Cells; Liver; Male; Microsomes; Polymerase Chain Reaction; Rats; RNA, Messenger

1997
11 beta-Hydroxysteroid dehydrogenase 1 activity and gene expression in human adipose stromal cells: effect on aromatase activity.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 60, Issue:3-4

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adolescent; Adult; Androstenedione; Aromatase; Breast; Carbenoxolone; Cells, Cultured; Cortisone; Drug Interactions; Estrone; Female; Gene Expression; Glucocorticoids; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Isoenzymes; Mammaplasty; Middle Aged; Stromal Cells

1997
Regulation of 11 beta-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes.
    The Journal of endocrinology, 1998, Volume: 156, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Animals; Blotting, Northern; Carbenoxolone; Cells, Cultured; Child; Corticosterone; Cortisone; Humans; Hydroxysteroid Dehydrogenases; Isoenzymes; Liver; Male; Middle Aged; Progesterone; Rats; Rats, Wistar; RNA, Messenger; Species Specificity; Triiodothyronine

1998
Osteoprogenitor cells in cell populations derived from mouse and rat calvaria differ in their response to corticosterone, cortisol, and cortisone.
    Bone, 1998, Volume: 23, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Carbenoxolone; Cell Division; Cells, Cultured; Corticosterone; Cortisone; Dose-Response Relationship, Drug; Hydrocortisone; Mice; Rats; Rats, Wistar; Skull; Species Specificity; Stem Cells

1998
Inhibition of renal 11beta-hydroxysteroid dehydrogenase in vivo by carbenoxolone in the rat and its relationship to sodium excretion.
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cortisone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrocortisone; Hydroxysteroid Dehydrogenases; Kidney; Male; NAD; NADP; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Tritium

1998
Expression and putative role of 11 beta-hydroxysteroid dehydrogenase isozymes within the human eye.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:9

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; 11-beta-Hydroxysteroid Dehydrogenases; Adult; Anterior Eye Segment; Carbenoxolone; Ciliary Body; Cortisone; Enzyme Inhibitors; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Immunoenzyme Techniques; Intraocular Pressure; Isoenzymes; Male; Middle Aged; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2001
Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes.
    European journal of clinical investigation, 2005, Volume: 35, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Carbenoxolone; Cortisone; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Humans; Hydrocortisone; Insulin Resistance; Liver X Receptors; Middle Aged; Muscle Fibers, Skeletal; Obesity; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid

2005
The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate.
    Biochimica et biophysica acta, 2006, Volume: 1764, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Carbenoxolone; CHO Cells; Cortisone; Cricetinae; Cricetulus; Glycyrrhetinic Acid; Humans; Hydrocortisone; Hydrogen Bonding; Kinetics; Models, Molecular; Substrate Specificity; Tyrosine

2006
Effect of immunosuppressive and other drugs on the cortisol-cortisone shuttle in human kidney and liver.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2007, Volume: 39, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aged; Aged, 80 and over; Biological Transport; Carbenoxolone; Cortisone; Female; Glycyrrhetinic Acid; Humans; Hydrocortisone; Immunosuppressive Agents; Kidney; Liver; Male; Middle Aged; Pharmaceutical Preparations; Steroids

2007
Inactivation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase enzymes increases during the meiotic maturation of porcine oocytes.
    Reproduction (Cambridge, England), 2008, Volume: 136, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cells, Cultured; Cortisone; Female; Follicular Fluid; Glucocorticoids; Glycyrrhetinic Acid; Hydrocortisone; Isoenzymes; Meiosis; Oocytes; Swine

2008
IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Volume: 303, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Asthma; Bronchoconstrictor Agents; Carbenoxolone; Chemokines, CC; Cortisone; Gene Expression; Glucocorticoids; Hydrocortisone; Interleukin-13; Isoenzymes; Lung; Methacholine Chloride; Muscle, Smooth; Pneumonia; Rabbits; Respiratory Mucosa; Trachea

2012
Effects of Carbenoxolone on the Canine Pituitary-Adrenal Axis.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; ACTH-Secreting Pituitary Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbenoxolone; Cortisone; Dogs; Gene Expression; Hydrocortisone; Pituitary ACTH Hypersecretion; Pituitary Gland; Pituitary-Adrenal System; Pro-Opiomelanocortin; RNA, Messenger

2015