Page last updated: 2024-08-24

carbenoxolone sodium and Diabetes Mellitus, Type 2

carbenoxolone sodium has been researched along with Diabetes Mellitus, Type 2 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fotsch, C; Wang, M1
Dhanesha, N; Dhote, V; Jain, M; Joharapurkar, A; Kshirsagar, S; Shah, G; Sharma, A1
Andrews, RC; Rooyackers, O; Walker, BR1
Abdallah, BM; Beck-Nielsen, H; Gaster, M1
Davani, B; Efendic, S; Hult, M; Jörnvall, H; Khan, A; Mårtensson, E; Okret, S; Oppermann, UC1

Trials

1 trial(s) available for carbenoxolone sodium and Diabetes Mellitus, Type 2

ArticleYear
Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Blood Glucose; Blood Pressure; Carbenoxolone; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Electrolytes; Enzyme Inhibitors; Humans; Hydroxysteroid Dehydrogenases; Insulin Resistance; Kinetics; Lipids; Male; Middle Aged

2003

Other Studies

4 other study(ies) available for carbenoxolone sodium and Diabetes Mellitus, Type 2

ArticleYear
Blockade of glucocorticoid excess at the tissue level: inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 as a therapy for type 2 diabetes.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucocorticoids; Glycyrrhetinic Acid; Humans; Insulin Resistance; Obesity

2008
Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Animals; Anti-Obesity Agents; Brain; Carbenoxolone; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Female; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Liver; Metabolic Syndrome; Mice; Mice, Mutant Strains; Obesity; Pancreas; Phosphoenolpyruvate Carboxykinase (ATP)

2012
Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes.
    European journal of clinical investigation, 2005, Volume: 35, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Carbenoxolone; Cortisone; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Humans; Hydrocortisone; Insulin Resistance; Liver X Receptors; Middle Aged; Muscle Fibers, Skeletal; Obesity; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid

2005
Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets.
    The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Anti-Ulcer Agents; Carbenoxolone; Corticosterone; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Genes, Reporter; Glucocorticoids; Glucose; Humans; Hydroxysteroid Dehydrogenases; Insulin; Islets of Langerhans; Isoenzymes; Kinetics; Ligands; Mice; Mice, Knockout; Mice, Mutant Strains; Pancreas; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Transcription, Genetic

2000