carbenoxolone sodium has been researched along with corticosterone in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.16) | 18.7374 |
| 1990's | 27 (55.10) | 18.2507 |
| 2000's | 14 (28.57) | 29.6817 |
| 2010's | 4 (8.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Latif, SA; Morris, DJ; Semafuko, WE | 1 |
| Gomez-Sanchez, CE; Gomez-Sanchez, EP | 1 |
| Brem, AS; Matheson, KL; Morris, DJ | 1 |
| Morris, DJ; Souness, GW | 3 |
| Krozowski, ZS; Mercer, WR | 1 |
| Fejes-Tóth, G; Náray-Fejes-Tóth, A; Watlington, CO | 1 |
| Blot-Chabaud, M; Bonvalet, JP; Doignon, I; Farman, N; Pradelles, P | 1 |
| Edwards, CR; Gaeggeler, HP; Rossier, BC | 1 |
| Brem, AS; Conca, T; Matheson, KL; Morris, DJ | 1 |
| Funder, JW; Pearce, PT; Smith, AI; Smith, R | 1 |
| Bina, RB; Brem, AS; King, T; Morris, DJ | 1 |
| Reeves, WB | 1 |
| Miksík, I; Pácha, J | 1 |
| Edwards, CR; Sang, KS; Walker, BR; Williams, BC | 1 |
| Morris, DJ; Myles, K; Souness, GW | 1 |
| Duperrex, H; Gaeggeler, HP; Hautier, S; Rossier, BC | 1 |
| Edwards, CR; Lindsay, RM; Lindsay, RS; Seckl, JR | 1 |
| Funder, JW; Sheppard, KE | 1 |
| de Kloet, ER; Oitzl, MS; Sutanto, W; van Haarst, AD; Welberg, LA | 1 |
| Khan, N; Muneyyirci-Delale, O; Nacharaju, VL | 1 |
| Fraser, R; Holloway, CD; Kenyon, CJ; Panarelli, M; Soro, A | 1 |
| Eggo, MC; Hewison, M; Ricketts, ML; Shoesmith, KJ; Stewart, PM; Strain, A | 1 |
| Sheppard, KE | 1 |
| Khoo, K; Krozowski, ZS; Li, KX; Sheppard, KE | 1 |
| Bellows, CG; Ciaccia, A; Heersche, JN | 1 |
| Leckie, CM; Seckl, JR; Welberg, LA | 1 |
| Ajilore, OA; Sapolsky, RM | 1 |
| Bens, M; Cluzeaud, F; Kahn, A; Pascual-Letallec, L; Rafestin-Oblin, ME; Rossier, BC; Vallet, V; Vandewalle, A | 1 |
| Bina, RB; Brem, AS; Fitzpatrick, C; Ingelfinger, JR; King, T; Tang, SS | 1 |
| Holmes, MC; Seckl, JR; Welberg, LA | 1 |
| Andrew, R; Chapman, KE; Jamieson, PM; Rossiter, S; Seckl, JR; Walker, BR | 1 |
| Davani, B; Efendic, S; Hult, M; Jörnvall, H; Khan, A; Mårtensson, E; Okret, S; Oppermann, UC | 1 |
| Biller, KJ; Shirley, DG; Unwin, RJ | 1 |
| Bailey, MA; Shirley, DG; Unwin, RJ | 1 |
| Bryndová, J; Pácha, J; Vagnerová, R | 1 |
| Michael, KK; Prough, RA; Ripp, SL; Robinzon, B; Winters, SJ | 1 |
| Ageloff, S; Brandt, W; Chou, CL; Fenton, RA; Knepper, MA; Stokes, JB | 1 |
| Dong, Q; Ge, RS; Hardy, MP; Latif, SA; Morris, DJ; Sottas, CM | 1 |
| Liang, M; Liu, Y; Netzel, BC; Raff, H; Singh, RJ; Usa, K | 1 |
| Hachey, DL; Hasty, AH; Nuotio-Antar, AM | 1 |
| Bryndová, J; Ergang, P; Kment, M; Leden, P; Miksík, I; Pácha, J; Zbánková, S | 1 |
| Flatt, PR; Gault, VA; Irwin, N; McKillop, AM; Taylor, A | 1 |
| Du, H; Friedman, TC; Liu, L; Liu, Y; Lutfy, K; Nakagawa, Y; Ren, X; Wang, W; Wang, Y | 1 |
| Acharya, V; Ayyalasomayajula, V; Koppala, SR; Nemani, H; Ponday, LR; Pothana, S; Prasad Sakamuri, SS; Prathipati, VK; Putcha, UK; Sukapaka, M; Veetill, GN | 1 |
| Halemani, PD; Mohan, CG; Rajendra, CE; Savinay, G; Viswanatha, GL | 1 |
| Andrikopoulos, P; Caton, PW; Chapagain, A; Corder, R; Harwood, SM; Kieswich, J; Long, JH; Nayuni, N; Raftery, MJ; Seckl, JR; Thiemermann, C; Walker, BR; Webster, SP; Yaqoob, MM | 1 |
| Elias, PM; Holleran, WM; Hupe, M; Mauro, T; Tiganescu, A; Uchida, Y | 1 |
49 other study(ies) available for carbenoxolone sodium and corticosterone
| Article | Year |
|---|---|
Effects of carbenoxolone administered acutely to adrenalectomized rats (in vivo) on renal and hepatic handling of corticosterone by 11 beta-hydroxysteroid dehydrogenase.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenalectomy; Animals; Carbenoxolone; Chromatography, High Pressure Liquid; Corticosterone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley | 1992 |
Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone.
Topics: Administration, Oral; Animals; Blood Pressure; Brain; Carbenoxolone; Corticosterone; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Spironolactone | 1992 |
Effect of carbenoxolone sodium on steroid-induced sodium transport in the toad bladder: further studies.
Topics: Aldosterone; Animals; Biological Transport; Bufo marinus; Carbenoxolone; Corticosterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Glucocorticoids; Sodium; Urinary Bladder | 1992 |
The "mineralocorticoid-like" actions conferred on corticosterone by carbenoxolone are inhibited by the mineralocorticoid receptor (type I) antagonist RU28318.
Topics: Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Corticosterone; Creatinine; Desoxycorticosterone; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1991 |
Localization of an 11 beta hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Corticosterone; Hydroxysteroid Dehydrogenases; Kidney; Male; NAD; NADP; Nephrons; Rats; Rats, Inbred Strains | 1992 |
11 beta-Hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Carbenoxolone; Cells, Cultured; Corticosterone; Hydroxysteroid Dehydrogenases; Kidney Tubules, Collecting; Kinetics; Rabbits | 1991 |
Distribution of 11 beta-hydroxysteroid dehydrogenase along the rabbit nephron.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Carbenoxolone; Corticosterone; Hydroxysteroid Dehydrogenases; Kidney Tubules; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Loop of Henle; Rabbits; Tissue Distribution | 1990 |
Steroid metabolism determines mineralocorticoid specificity in the toad bladder.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Biological Evolution; Biological Transport, Active; Bufo marinus; Carbenoxolone; Corticosterone; Electric Conductivity; Epithelium; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mucous Membrane; Sodium; Urinary Bladder | 1989 |
Effect of carbenoxolone on glucocorticoid metabolism and Na transport in toad bladder.
Topics: Animals; Biological Transport, Active; Bufo marinus; Carbenoxolone; Corticosterone; Glucocorticoids; Glycyrrhetinic Acid; In Vitro Techniques; Kinetics; Sodium; Urinary Bladder | 1989 |
Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated.
Topics: Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Colon; Corticosterone; Heart; Hippocampus; Hydrocortisone; Hydroxysteroid Dehydrogenases; Kidney; Parotid Gland; Rats; Receptors, Mineralocorticoid; Receptors, Steroid | 1988 |
The antinatriuretic and kaliuretic effects of the glucocorticoids corticosterone and cortisol following pretreatment with carbenoxolone sodium (a liquorice derivative) in the adrenalectomized rat.
Topics: Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Glycyrrhetinic Acid; Hydrocortisone; Male; Natriuresis; Potassium; Rats; Rats, Inbred Strains | 1989 |
Bidirectional activity of 11 beta-hydroxysteroid dehydrogenase in vascular smooth muscle cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Aorta; Carbenoxolone; Cell Division; Cells, Cultured; Corticosterone; Gene Expression; Hydroxysteroid Dehydrogenases; Kinetics; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
NAD-dependent 11 beta-hydroxysteroid dehydrogenase in cultured human colonic epithelial cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Aldosterone; Carbenoxolone; Cell Line; Colonic Neoplasms; Corticosterone; Epithelium; Gene Expression; Humans; Hydroxysteroid Dehydrogenases; Kinetics; NAD; NADP; Receptors, Mineralocorticoid; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Distribution of 11 beta-hydroxysteroid dehydrogenase along the rat intestine.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Cecum; Chromatography, High Pressure Liquid; Colon; Corticosterone; Duodenum; Hydroxysteroid Dehydrogenases; Intestinal Mucosa; Intestines; Jejunum; Male; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Sodium | 1994 |
Direct and indirect effects of carbenoxolone on responses to glucocorticoids and noradrenaline in rat aorta.
Topics: Adrenalectomy; Animals; Aorta; Carbenoxolone; Corticosterone; Glucocorticoids; In Vitro Techniques; Male; Mifepristone; Norepinephrine; Rats; Rats, Wistar; Spironolactone; Vasoconstriction | 1994 |
Other physiological considerations of protective mechanisms of mineralocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Carbenoxolone; Corticosterone; Cortisone; Cortodoxone; Hydroxysteroid Dehydrogenases; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley | 1994 |
11-Dehydrocorticosterone in the presence of carbenoxolone is a more potent sodium retainer than corticosterone.
Topics: Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Creatinine; Male; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Spironolactone | 1993 |
Corticosterone induces 11 beta-HSD and mineralocorticoid specificity in an amphibian urinary bladder cell line.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Binding, Competitive; Biological Transport; Bufo marinus; Carbenoxolone; Cell Line; Corticosterone; Dose-Response Relationship, Drug; Epithelium; Hydroxysteroid Dehydrogenases; Mineralocorticoids; Sodium; Time Factors; Urinary Bladder | 1993 |
Inhibition of 11-beta-hydroxysteroid dehydrogenase in pregnant rats and the programming of blood pressure in the offspring.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Animals; Birth Weight; Blood Glucose; Blood Pressure; Carbenoxolone; Corticosterone; Female; Fetal Growth Retardation; Hydroxysteroid Dehydrogenases; Male; Pregnancy; Rats; Rats, Wistar | 1996 |
Specific nuclear localization of 11-dehydrocorticosterone in rat colon: evidence for a novel corticosteroid receptor.
Topics: Aldosterone; Animals; Binding, Competitive; Carbenoxolone; Cell Nucleus; Colon; Corticosterone; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Tissue Distribution | 1996 |
11 beta-Hydroxysteroid dehydrogenase activity in the hippocampus: implications for in vivo corticosterone receptor binding and cell nuclear retention.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Autoradiography; Carbenoxolone; Cell Nucleus; Corticosterone; Enzyme Inhibitors; Glycyrrhetinic Acid; Hippocampus; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, Steroid; Regression Analysis | 1996 |
Presence of 11 beta-hydroxysteroid dehydrogenase in human semen: evidence of correlation with semen characteristics.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carbenoxolone; Corticosterone; Humans; Hydroxysteroid Dehydrogenases; Male; NAD; NADP; Oligospermia; Semen; Sperm Motility; Spermatozoa | 1997 |
In vivo and in vitro effects of carbenoxolone on glucocorticoid receptor binding and glucocorticoid activity.
Topics: Animals; Anti-Ulcer Agents; Binding, Competitive; Blood Pressure; Carbenoxolone; Corticosterone; Cytosol; Dexamethasone; In Vitro Techniques; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Weight Gain | 1997 |
Regulation of 11 beta-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Animals; Blotting, Northern; Carbenoxolone; Cells, Cultured; Child; Corticosterone; Cortisone; Humans; Hydroxysteroid Dehydrogenases; Isoenzymes; Liver; Male; Middle Aged; Progesterone; Rats; Rats, Wistar; RNA, Messenger; Species Specificity; Triiodothyronine | 1998 |
Decreased apparent affinity of corticosterone for colonic crypt glucocorticoid receptors is dependent on the cellular milieu and is distinct from corticosterone metabolism.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Carbenoxolone; Colon; Corticosterone; Cytosol; Dexamethasone; Enzyme Inhibitors; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid | 1998 |
Steroid specificity of the putative DHB receptor: evidence that the receptor is not 11betaHSD.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cell Nucleus; Cells, Cultured; CHO Cells; Colon; Corticosterone; Cricetinae; Culture Media, Conditioned; Hydroxysteroid Dehydrogenases; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spironolactone; Substrate Specificity; Transfection | 1998 |
Osteoprogenitor cells in cell populations derived from mouse and rat calvaria differ in their response to corticosterone, cortisol, and cortisone.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Carbenoxolone; Cell Division; Cells, Cultured; Corticosterone; Cortisone; Dose-Response Relationship, Drug; Hydrocortisone; Mice; Rats; Rats, Wistar; Skull; Species Specificity; Stem Cells | 1998 |
11beta-hydroxysteroid dehydrogenase is a predominant reductase in intact rat Leydig cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cells, Cultured; Corticosterone; Dexamethasone; Glucocorticoids; Hydroxysteroid Dehydrogenases; Kidney; Leydig Cells; Liver; Luteinizing Hormone; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Testis; Testosterone | 1998 |
In vivo characterization of 11beta-hydroxysteroid dehydrogenase in rat hippocampus using glucocorticoid neuroendangerment as an endpoint.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Drug Implants; Enzyme Inhibitors; Glucocorticoids; Hippocampus; Hydroxysteroid Dehydrogenases; Kainic Acid; Male; Rats; Rats, Sprague-Dawley | 1999 |
Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line.
Topics: Adenosine; Adrenal Cortex Hormones; Amiloride; Animals; Biological Transport; Carbenoxolone; Cell Line, Transformed; Cells, Cultured; Corticosterone; Dose-Response Relationship, Drug; Electrophysiology; Epithelial Sodium Channels; Kidney Tubules, Collecting; Male; Mice; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium; Sodium Channels; Substrate Specificity; Time Factors | 1999 |
Glucocorticoid metabolism in proximal tubules modulates angiotensin II-induced electrolyte transport.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Angiotensin II; Animals; Biological Transport; Carbenoxolone; Cell Line, Transformed; Corticosterone; Enzyme Inhibitors; Glucocorticoids; Hydroxysteroid Dehydrogenases; Kidney Tubules, Proximal; Rats; Rats, Wistar | 1999 |
Inhibition of 11beta-hydroxysteroid dehydrogenase, the foeto-placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety-like behaviour in the offspring.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Amygdala; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Carbenoxolone; Corticosterone; Depression; Enzyme Inhibitors; Female; Glucocorticoids; Hydroxysteroid Dehydrogenases; Hypothalamo-Hypophyseal System; In Situ Hybridization; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Swimming | 2000 |
11 beta-hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Corticosterone; Dose-Response Relationship, Drug; Female; Hydroxysteroid Dehydrogenases; Liver; Male; Rats; Sex Characteristics | 2000 |
Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Anti-Ulcer Agents; Carbenoxolone; Corticosterone; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Genes, Reporter; Glucocorticoids; Glucose; Humans; Hydroxysteroid Dehydrogenases; Insulin; Islets of Langerhans; Isoenzymes; Kinetics; Ligands; Mice; Mice, Knockout; Mice, Mutant Strains; Pancreas; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Transcription, Genetic | 2000 |
Distal tubular electrolyte transport during inhibition of renal 11beta-hydroxysteroid dehydrogenase.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Electrolytes; Glomerular Filtration Rate; Hematocrit; Hydroxysteroid Dehydrogenases; Kidney Tubules, Distal; Male; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Sodium | 2001 |
In vivo inhibition of renal 11beta-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption.
Topics: Absorption; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carbenoxolone; Carbon Radioisotopes; Corticosterone; Enzyme Inhibitors; Hydroxysteroid Dehydrogenases; Kidney Tubules, Collecting; Photometry; Rats; Rats, Sprague-Dawley; Sodium; Sodium Radioisotopes | 2001 |
Carbenoxolone accelerates maturation of rat intestine.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Animals, Newborn; Anti-Ulcer Agents; Carbenoxolone; Corticosterone; Enzyme Inhibitors; Female; Intestinal Mucosa; Intestines; Pregnancy; Rats | 2003 |
Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cell Nucleus; Corticosterone; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kidney; Kinetics; Liver; Male; Microsomes; Mitochondria; Models, Biological; NAD; NADP; Rats; Rats, Sprague-Dawley; Species Specificity; Sus scrofa | 2003 |
Increased collecting duct urea transporter expression in Dahl salt-sensitive rats.
Topics: Animals; Blotting, Western; Carbenoxolone; Carrier Proteins; Corticosterone; Gene Expression Regulation; Hydroxysteroid Dehydrogenases; Immunohistochemistry; Kidney Medulla; Kidney Tubules, Collecting; Membrane Glycoproteins; Membrane Transport Proteins; Rats; Rats, Inbred Dahl; RNA, Messenger; Urea Transporters | 2003 |
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Binding Sites; Carbenoxolone; Corticosterone; Drug Synergism; In Vitro Techniques; Leydig Cells; Male; Mineralocorticoid Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Testosterone | 2005 |
Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Blood Pressure; Blotting, Western; Carbenoxolone; Circadian Rhythm; Corticosterone; Enzyme Inhibitors; Immunohistochemistry; Kidney; Kidney Medulla; Male; Microdialysis; Potassium; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Tandem Mass Spectrometry | 2007 |
Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Agouti Signaling Protein; Animals; Atherosclerosis; Blood Pressure; Body Weight; Carbenoxolone; Corticosterone; Energy Metabolism; Fatty Liver; Female; Hyperinsulinism; Hyperlipidemias; Lipoproteins, VLDL; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; Receptors, LDL | 2007 |
Glucocorticoid availability in colonic inflammation of rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Budesonide; Carbenoxolone; Colitis; Colon; Corticosterone; Cyclooxygenase 2; Disease Models, Animal; Glucocorticoids; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Mucin-2; Mucins; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2008 |
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Corticosterone; Dietary Fats; Eating; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Mice; Obesity; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Carbohydrate Dehydrogenases; Cells, Cultured; Corticosterone; Deoxyglucose; Dietary Fats; Gene Expression; Glucose Tolerance Test; Hepatocytes; Homeostasis; Immunoblotting; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Glucocorticoid; RNA, Messenger | 2008 |
Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adipose Tissue; Adrenal Glands; Animals; Body Composition; Carbenoxolone; Cholesterol, HDL; Corticosterone; Eating; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Glucose Intolerance; Glycogen; Hypertrophy; Liver; Male; Metabolic Syndrome; Obesity; Organ Size; Rats; Signal Transduction; Thinness; Triglycerides | 2012 |
1,2,3,4,6 Penta-O-galloyl-β-d-glucose, a bioactivity guided isolated compound from Mangifera indica inhibits 11β-HSD-1 and ameliorates high fat diet-induced diabetes in C57BL/6 mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue, White; Animals; Body Weight; Carbenoxolone; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucose Tolerance Test; Hydrolyzable Tannins; Hypoglycemic Agents; Insulin; Liver; Male; Mangifera; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Leaves | 2013 |
Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Analysis of Variance; Animals; Blood Glucose; Carbenoxolone; Corticosterone; Cytokines; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; Immunoblotting; Insulin; Insulin Resistance; Liver; Mice; Mice, Knockout; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Renal Insufficiency, Chronic; RNA, Messenger; Uremia | 2014 |
Topical 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Corrects Cutaneous Features of Systemic Glucocorticoid Excess in Female Mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Administration, Topical; Animals; Anti-Inflammatory Agents; Carbenoxolone; Corticosterone; Cytokines; Drug Eruptions; Enzyme Inhibitors; Epidermis; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Glucocorticoids; Granulation Tissue; Mice, Hairless; Organ Size; Skin; Wound Healing | 2018 |