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carbenoxolone sodium and Insulin Sensitivity

carbenoxolone sodium has been researched along with Insulin Sensitivity in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Abdel-Hady, EA; Bahaa, I; Saleh, N; Seif, AA1
Chen, Y; Qian, Q; Yu, J1
Campello, RS; Machado, UF; Mori, RC; Poças da Silva, T1
Andrikopoulos, P; Caton, PW; Chapagain, A; Corder, R; Harwood, SM; Kieswich, J; Long, JH; Nayuni, N; Raftery, MJ; Seckl, JR; Thiemermann, C; Walker, BR; Webster, SP; Yaqoob, MM1
Iwamura, T; Kainoh, M; Kawai, K; Kumagai, H; Nakaki, J; Nitta, A; Okazaki, S; Sakami, S; Sato, M; Sekiya, Y; Takahashi, T; Yagi, M1
Du, H; Friedman, TC; Liu, L; Liu, Y; Lutfy, K; Nakagawa, Y; Ren, X; Wang, W; Wang, Y1
Fotsch, C; Wang, M1
Dhanesha, N; Dhote, V; Jain, M; Joharapurkar, A; Kshirsagar, S; Shah, G; Sharma, A1
Andrews, RC; Rooyackers, O; Walker, BR1
Abdallah, BM; Beck-Nielsen, H; Gaster, M1
Flatt, PR; Gault, VA; Irwin, N; McKillop, AM; Taylor, A1

Trials

1 trial(s) available for carbenoxolone sodium and Insulin Sensitivity

ArticleYear
Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Blood Glucose; Blood Pressure; Carbenoxolone; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Electrolytes; Enzyme Inhibitors; Humans; Hydroxysteroid Dehydrogenases; Insulin Resistance; Kinetics; Lipids; Male; Middle Aged

2003

Other Studies

10 other study(ies) available for carbenoxolone sodium and Insulin Sensitivity

ArticleYear
Comparative effect of vitamin D3 and carbenoxolone treatments in metabolic syndrome rats.
    Canadian journal of physiology and pharmacology, 2022, Volume: 100, Issue:5

    Topics: Animals; Blood Glucose; Carbenoxolone; Cholecalciferol; Insulin Resistance; Metabolic Syndrome; Rats; Rats, Wistar

2022
Carbenoxolone ameliorates insulin sensitivity in obese mice induced by high fat diet via regulating the IκB-α/NF-κB pathway and NLRP3 inflammasome.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 115

    Topics: Animals; Carbenoxolone; Diet, High-Fat; Gene Expression Regulation; Inflammation; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NF-kappa B; NF-KappaB Inhibitor alpha; NLR Family, Pyrin Domain-Containing 3 Protein; Obesity; Random Allocation

2019
Carbenoxolone enhances peripheral insulin sensitivity and GLUT4 expression in skeletal muscle of obese rats: Potential participation of UBC9 protein.
    Life sciences, 2019, Jul-15, Volume: 229

    Topics: Animals; Anti-Ulcer Agents; Carbenoxolone; Gene Expression Regulation; Glucose Transporter Type 4; Hyperinsulinism; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Rats; Rats, Wistar; Ubiquitin-Conjugating Enzymes

2019
Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-11, Volume: 111, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Analysis of Variance; Animals; Blood Glucose; Carbenoxolone; Corticosterone; Cytokines; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; Immunoblotting; Insulin; Insulin Resistance; Liver; Mice; Mice, Knockout; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Renal Insufficiency, Chronic; RNA, Messenger; Uremia

2014
HIS-388, a novel orally active and long-acting 11β-hydroxysteroid dehydrogenase type 1 inhibitor, ameliorates insulin sensitivity and glucose intolerance in diet-induced obesity and nongenetic type 2 diabetic murine models.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adamantane; Administration, Oral; Animals; Azepines; Carbenoxolone; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Resistance; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Obesity; Pioglitazone; Thiazolidinediones; Triazoles

2014
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
    Journal of molecular endocrinology, 2008, Volume: 41, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Carbohydrate Dehydrogenases; Cells, Cultured; Corticosterone; Deoxyglucose; Dietary Fats; Gene Expression; Glucose Tolerance Test; Hepatocytes; Homeostasis; Immunoblotting; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Glucocorticoid; RNA, Messenger

2008
Blockade of glucocorticoid excess at the tissue level: inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 as a therapy for type 2 diabetes.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucocorticoids; Glycyrrhetinic Acid; Humans; Insulin Resistance; Obesity

2008
Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Animals; Anti-Obesity Agents; Brain; Carbenoxolone; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Female; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Liver; Metabolic Syndrome; Mice; Mice, Mutant Strains; Obesity; Pancreas; Phosphoenolpyruvate Carboxykinase (ATP)

2012
Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes.
    European journal of clinical investigation, 2005, Volume: 35, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Carbenoxolone; Cortisone; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Humans; Hydrocortisone; Insulin Resistance; Liver X Receptors; Middle Aged; Muscle Fibers, Skeletal; Obesity; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid

2005
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
    Biological chemistry, 2008, Volume: 389, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Corticosterone; Dietary Fats; Eating; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Mice; Obesity; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction

2008