Compounds > carbenoxolone sodium
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carbenoxolone sodium and Disease Models, Animal

carbenoxolone sodium has been researched along with Disease Models, Animal in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.94)18.7374
1990's0 (0.00)18.2507
2000's28 (41.18)29.6817
2010's31 (45.59)24.3611
2020's7 (10.29)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Cheng, Q; He, F; Li, N; Shang, Y1
Fan, ZR; Li, L; Li, XZ; Liu, LQ; Ma, KT; Si, JQ; Wang, L; Zhang, LΖ1
Chen, NH; Chu, SF; Feng, ST; Jin, C; Lou, YX; Qu, TG; Ren, SY; Wang, HQ; Wang, ZZ; Xia, CY; Zhang, Y1
Bai, W; Bi, F; Hao, Y; Li, H; Liu, X; Xu, X; Yang, Q; Yang, R1
Nehru, B; Saini, A; Sharma, S1
Dong, S; Shi, Y; Zhang, K1
Baird-Daniel, E; Daniel, AGS; Laffont, P; Li, D; Liou, JY; Ma, H; Schwartz, TH; Wenzel, M; Yuste, R; Zhao, M1
Berta, T; Chen, G; Ji, RR; Luo, X; Qadri, MY1
Ballesteros-Zebadua, P; Castro, N; Franco-Pérez, J; Manjarrez-Marmolejo, J; Rodríguez-Balderas, C1
Falk, S1
Bajwa, A; Huang, L; Isakson, BE; Jankowski, J; Lorenz, UM; Medina, CB; Okusa, MD; Perry, HM; Ravichandran, KS; Rosin, DL; Yao, J1
Ashrafi-Helan, J; Jafari-Khataylou, Y; Rasouli, M1
Belzer, V; Hanani, M; Hanstein, R; Iglesias, R; Shraer, N; Spray, DC; Suadicani, SO1
Jing, YH; Li, YM; Song, YF; Wang, SY; Yin, J; Zhang, L1
Nehru, B; Thakur, P1
Dougherty, PM; Robinson, CR1
Gigout, S; Louvel, J; Pumain, R2
Gönczi, M; Kovács, M; Miskolczi, G; Seprényi, G; Végh, Á1
Duroux, M; Gazerani, P; Hanani, M; Poulsen, JN; Warwick, R1
Deng, J; Deng, W; He, J; Luo, L; Wang, DX1
Campana, WM; Collyer, E; Henry, KW; Ingves, M; Lee-Kubli, CA; Shiao, R; Tuszynski, MH1
Chen, J; Kawamura, T; Koob, GF; Repunte-Canonigo, V; Roberts, AJ; Sanna, PP; Vendruscolo, LF1
Gao, B; Wang, H; Xu, H; Zhang, Y1
Hong, T; Wang, H; Wang, Y1
Ghosh, B; Kumar, S; Ram, A; Singh, SK; Singh, VP1
Lekic, T; Manaenko, A; Sozen, T; Tang, J; Tsuchiyama, R; Zhang, JH1
Donnelly, DF; Lamotte, RH; Ma, C; Mei, X; White, FA; Zhang, H; Zhang, P1
Jacobson, G; Sleigh, JW; Steyn-Ross, A; Steyn-Ross, M; Voss, LJ1
Shintani-Ishida, K; Unuma, K; Yoshida, K1
Hosseinzadeh, SA; Khorasani, MZ; Vakili, A1
Cherkas, PS; Hanani, M; Smith, DN; Spray, DC; Suadicani, SO; Zuckerman, J1
Ayer, R; Chen, W; Sugawara, T; Suzuki, H; Zhang, JH1
Carvalho, JE; Castro, GA; Possenti, A; Sgarbieri, VC; Tinti, SV1
Menzler, J; Zeck, G1
Alessandri, B; Heimann, A; Kempski, O; Tamura, K1
Suzumura, A1
Poelzing, S; Salama, ME; Veeraraghavan, R1
Hong, S; Jung, Y; Kim, DD; Kim, H; Kim, YM; Kong, H; Lee, Y; Yoon, JH1
Chen, NH; Li, J; Liu, Y; Sun, JD; Yuan, YH1
Bauriedl, J; Bussek, A; Lohmann, H; Ravens, U; Schmidt, M; Wettwer, E1
Moreira, TS; Mulkey, DK; Sobrinho, CR; Takakura, AC; Wenker, IC1
Austin, JS; Beggs, S; Costigan, M; Diatchenko, L; Dorfman, R; Gershon, E; Herbert, TA; John, SL; Jordan, J; Livneh, J; Maixner, W; Mogil, JS; Peltz, G; Ritchie, J; Salter, MW; Seltzer, Z; Slade, GD; Smith, SB; Sorge, RE; Tan, K; Tichauer, D; Trang, T; Vander Meulen, H; Woolf, CJ; Yarkoni-Abitbul, M; Zaykin, DV; Zheng, M1
Harada, M; Honjo, H; Kamiya, K; Kato, S; Kodama, I; Opthof, T; Sakuma, I; Takanari, H; Takemoto, Y; Ueda, N; Yamazaki, M1
de Melo, IL; de Oliveira e Silva, AM; Farsky, SH; Machado, ID; Mancini-Filho, J; Santin, JR; Shimoyama, AT1
Antônio, MA; Bighetti, AE; Carvalho, JE; Rosaneli, CF; Sgarbieri, VC1
Hosseinzadeh, H; Nassiri Asl, M1
Antal, K; Kardos, J; Kovács, R; Lasztóczi, B; Nyikos, L1
Ali, KS; Gajda, Z; Gyengési, E; Hermesz, E; Szente, M1
Barresi, V; Belluardo, N; Citraro, R; Condorelli, D; De Sarro, G; Gareri, P; Ibbadu, GF; Mudò, G; Russo, E; Trovato-Salinaro, A; Trovato-Salinato, A1
Benabou, S; de Pina-Benabou, MH; Federoff, HJ; Kyrozis, A; Rempe, D; Rozental, R; Spray, DC; Stanton, PK; Szostak, V; Urban-Maldonado, M; Uziel, D1
Jeyapalan, Z; Kokarovtseva, L; Leshchenko, Y; Perez Velazquez, JL; Sarbaziha, R1
El-Beheiry, M; Khokhotva, V; Kokarovtseva, L; Leshchenko, Y; Perez Velazquez, JL; Proulx, E; Snead, OC1
Cao, R; Chen, LW; Duan, L; Gao, B; Qin, M; Rao, ZR; Wang, JJ; Xiong, YF; Zhang, H1
Handforth, A; Martin, FC1
Gajda, Z; Gyengési, E; Hermesz, E; Szente, M; Szupera, Z1
Cock, HR; Kelso, AR; Nilsen, KE1
Bağirici, F; Bostanci, MO1
Cao, R; Chen, LW; Duan, L; Gao, B; Lan, L; Rao, ZR; Shen, J; Xiong, Y; Yuan, H1
Dublin, P; Hanani, M1
Di Stasi, LC; Rocha, NP; Roldão, EF; Seito, LN; Witaicenis, A1
Bryndová, J; Ergang, P; Kment, M; Leden, P; Miksík, I; Pácha, J; Zbánková, S1
Hong, T; Wang, H; Wang, HT; Wang, Y1
Bracci, E; Gladwell, SJ; Jefferys, JG; Köhling, R; Vreugdenhil, M1
Bechberger, JF; Nakase, T; Naus, CC; Ozog, MA1
Mandell, C; Stein, TA; Strauss, RJ; Wise, L1
Naganuma, T; Okabe, S; Takagi, K; Takata, Y; Takeuchi, K1

Other Studies

68 other study(ies) available for carbenoxolone sodium and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Carbenoxolone Ameliorates Allergic Airway Inflammation through NF-κB/NLRP3 Pathway in Mice.
    Biological & pharmaceutical bulletin, 2022, Jun-01, Volume: 45, Issue:6

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbenoxolone; Caspase 1; Disease Models, Animal; Inflammasomes; Inflammation; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; NF-KappaB Inhibitor alpha; NLR Family, Pyrin Domain-Containing 3 Protein; Ovalbumin

2022
Carbenoxolone decreases monocrotaline‑induced pulmonary inflammation and pulmonary arteriolar remodeling in rats by decreasing the expression of connexins in T lymphocytes.
    International journal of molecular medicine, 2020, Volume: 45, Issue:1

    Topics: Animals; Biopsy; Carbenoxolone; Connexin 43; Connexins; Cytokines; Disease Models, Animal; Echocardiography; Gene Expression Regulation; Hemodynamics; Immunophenotyping; Inflammation Mediators; Male; Monocrotaline; Pneumonia; Pulmonary Fibrosis; Rats; T-Lymphocytes; Vascular Remodeling

2020
Connexin 43: A novel ginsenoside Rg1-sensitive target in a rat model of depression.
    Neuropharmacology, 2020, 06-15, Volume: 170

    Topics: Animals; Animals, Newborn; Astrocytes; Carbenoxolone; Cells, Cultured; Central Nervous System Agents; Connexin 43; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Ginsenosides; Male; Peptides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2020
Involvement of amylin B-H2S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia-reperfusion-induced myocardial injury in diabetic rats.
    Bioscience reports, 2020, 06-26, Volume: 40, Issue:6

    Topics: Amylin Receptor Agonists; Animals; Carbenoxolone; Connexin 43; Diabetic Angiopathies; Diabetic Cardiomyopathies; Disease Models, Animal; Hydrogen Sulfide; Islet Amyloid Polypeptide; Isolated Heart Preparation; Male; Mesenteric Arteries; Myocardial Reperfusion Injury; Myocardium; Rats, Wistar; Signal Transduction; Sulfides; Vasodilation

2020
Neuroprotective effects of carbenoxolone against amyloid-beta 1-42 oligomer-induced neuroinflammation and cognitive decline in rats.
    Neurotoxicology, 2021, Volume: 83

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Apoptosis; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Carbenoxolone; Cognition; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Encephalitis; GPI-Linked Proteins; Inflammation Mediators; Male; Memory; Monoamine Oxidase; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction

2021
Carbenoxolone has the potential to ameliorate acute incision pain in rats.
    Molecular medicine reports, 2021, Volume: 24, Issue:1

    Topics: Acute Pain; Animals; Astrocytes; Carbenoxolone; Connexin 43; Connexins; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley

2021
Glial Calcium Waves are Triggered by Seizure Activity and Not Essential for Initiating Ictal Onset or Neurovascular Coupling.
    Cerebral cortex (New York, N.Y. : 1991), 2017, 06-01, Volume: 27, Issue:6

    Topics: 4-Aminopyridine; Animals; Brain Mapping; Calcium; Calcium Signaling; Carbenoxolone; Diagnostic Imaging; Disease Models, Animal; Epilepsy; Evoked Potentials, Somatosensory; Male; Neuroglia; Neurons; Neurovascular Coupling; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Somatosensory Cortex; Tetrodotoxin

2017
Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocytes.
    Neuroscience bulletin, 2018, Volume: 34, Issue:1

    Topics: 2-Aminoadipic Acid; Animals; Anti-Inflammatory Agents; Astrocytes; Carbenoxolone; Caspase 6; Connexin 43; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glial Fibrillary Acidic Protein; Male; Mice; Mice, Transgenic; Microglia; Minocycline; Neuralgia; Pain Measurement; Phenylurea Compounds; Sex Characteristics; Spinal Cord; Time Factors

2018
Quinine and carbenoxolone enhance the anticonvulsant activity of some classical antiepileptic drugs.
    Neurological research, 2018, Volume: 40, Issue:1

    Topics: Animals; Anticonvulsants; Carbenoxolone; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroshock; Epilepsy; Male; Pentylenetetrazole; Quinine; Rats; Rats, Wistar

2018
Carbenoxolone as a novel therapy for attenuation of cancer-induced bone pain.
    Pain, 2018, Volume: 159, Issue:6

    Topics: Analgesics; Animals; Bone Neoplasms; Cancer Pain; Carbenoxolone; Cell Line, Tumor; Connexins; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Male; Pain Measurement; Random Allocation; Rats; Spinal Cord; Statistics, Nonparametric; Weight-Bearing

2018
Epithelial and Endothelial Pannexin1 Channels Mediate AKI.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:7

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Anti-Ulcer Agents; Bone Marrow Cells; Carbenoxolone; Connexins; Cytokines; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Epithelial Cells; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Reperfusion Injury; RNA, Messenger

2018
Carbenoxolone Could Deteriorate Streptozotocin-induced Diabetes through Induction of Heat Shock Protein 70 and IFN-γ in C57BL/6 Mice.
    Iranian journal of allergy, asthma, and immunology, 2018, Dec-01, Volume: 17, Issue:6

    Topics: Animals; Carbenoxolone; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; HSP70 Heat-Shock Proteins; Humans; Interferon-gamma; Interleukin-10; Interleukin-17; Male; Mice; Streptozocin; T-Lymphocytes, Regulatory

2018
Gap junction mediated signaling between satellite glia and neurons in trigeminal ganglia.
    Glia, 2019, Volume: 67, Issue:5

    Topics: Animals; Boron Compounds; Carbenoxolone; Cells, Cultured; Disease Models, Animal; Female; Flufenamic Acid; Gap Junctions; Heptanol; Inflammation; Isoquinolines; Lipopolysaccharides; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Probenecid; Synaptic Transmission; Trigeminal Ganglion

2019
Protective effects of carbenoxolone are associated with attenuation of oxidative stress in ischemic brain injury.
    Neuroscience bulletin, 2013, Volume: 29, Issue:3

    Topics: Animals; Astrocytes; Brain Injuries; Brain Ischemia; Carbenoxolone; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2013
Inhibition of neuroinflammation and mitochondrial dysfunctions by carbenoxolone in the rotenone model of Parkinson's disease.
    Molecular neurobiology, 2015, Volume: 51, Issue:1

    Topics: Animals; Antioxidants; Astrocytes; Carbenoxolone; Citrulline; Cytokines; Disease Models, Animal; Electron Transport; Enzyme Activation; Glial Fibrillary Acidic Protein; Glutathione; Inflammation; Inflammation Mediators; Male; Mesencephalon; Mitochondria; Nervous System; Nitric Oxide; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Sprague-Dawley; Rotenone

2015
Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy.
    Neuroscience, 2015, Jan-29, Volume: 285

    Topics: Animals; Astrocytes; Bortezomib; Carbenoxolone; Ceftriaxone; Central Nervous System Agents; Connexin 43; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gap Junctions; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Minocycline; Pain Threshold; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Spinal Cord

2015
Decrease of neocortical paired-pulse depression in GAERS and possible implication of gap junctions.
    Neuroscience letters, 2015, Jan-01, Volume: 584

    Topics: Animals; Anticonvulsants; Carbenoxolone; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Gap Junctions; In Vitro Techniques; Neocortex; Quinidine; Rats, Wistar; Species Specificity; Synaptic Transmission

2015
Further evidence for the role of gap junctions in the delayed antiarrhythmic effect of cardiac pacing.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:7

    Topics: Animals; Arrhythmias, Cardiac; Carbenoxolone; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Gap Junctions; Male; Time Factors

2015
Oxaliplatin enhances gap junction-mediated coupling in cell cultures of mouse trigeminal ganglia.
    Experimental cell research, 2015, Aug-01, Volume: 336, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents; Carbenoxolone; Cells, Cultured; Connexin 43; Disease Models, Animal; Female; Fluorescent Antibody Technique; Gap Junctions; Male; Mice; Mice, Inbred BALB C; Neuroglia; Organoplatinum Compounds; Oxaliplatin; Satellite Cells, Perineuronal; Trigeminal Ganglion

2015
Regulation of epithelial sodium channel expression by oestradiol and progestogen in alveolar epithelial cells.
    Respiratory physiology & neurobiology, 2015, Sep-15, Volume: 216

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Acute Lung Injury; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Carbenoxolone; Dexamethasone; Disease Models, Animal; Epithelial Cells; Epithelial Sodium Channels; Estradiol; Female; Gene Expression Regulation; Glucocorticoids; Lung; Male; Oleic Acid; Progestins; Pulmonary Edema; Rats; Rats, Sprague-Dawley

2015
Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury.
    Experimental neurology, 2016, Volume: 278

    Topics: Amines; Animals; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Carbenoxolone; Connexin 43; Cyclohexanecarboxylic Acids; Disease Models, Animal; Escape Reaction; Female; Forelimb; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hyperalgesia; Lectins; Microfilament Proteins; Motor Activity; Pain; Pain Measurement; Rats; Rats, Inbred F344; Spinal Cord; Spinal Cord Injuries; Tubulin

2016
11β-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse.
    Translational psychiatry, 2016, Mar-15, Volume: 6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Binge Drinking; Carbenoxolone; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Drinking Behavior; Ethanol; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; Self Administration

2016
Effects of inhibiting connexin43 on expression of fibroblast growth factor in prolactinomas in rats.
    Neurological research, 2016, Volume: 38, Issue:5

    Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Estradiol; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Organ Size; Pituitary Gland; Pituitary Neoplasms; Prolactinoma; Rats

2016
Effects of gap junctional blockers on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
    Neurological research, 2009, Volume: 31, Issue:3

    Topics: Animals; Basilar Artery; Carbenoxolone; Connexin 43; Disease Models, Animal; Down-Regulation; Electrical Synapses; Male; Octanols; Rabbits; Radiography; Random Allocation; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2009
Inhaled carbenoxolone prevents allergic airway inflammation and airway hyperreactivity in a mouse model of asthma.
    International archives of allergy and immunology, 2009, Volume: 149, Issue:1

    Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbenoxolone; Disease Models, Animal; Immunoglobulin E; Lung; Male; Mice; Mice, Inbred BALB C; Nebulizers and Vaporizers; Ovalbumin

2009
Effect of gap junction inhibition on intracerebral hemorrhage-induced brain injury in mice.
    Neurological research, 2009, Volume: 31, Issue:2

    Topics: Animals; Brain Edema; Brain Injuries; Carbenoxolone; Catalepsy; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Functional Laterality; Gap Junctions; Male; Mice; Neurologic Examination; Survival Analysis; Time Factors

2009
Altered functional properties of satellite glial cells in compressed spinal ganglia.
    Glia, 2009, Nov-15, Volume: 57, Issue:15

    Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Biophysics; Carbenoxolone; Cesium; Chlorides; Disease Models, Animal; Electric Stimulation; Female; Ganglia, Spinal; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Logistic Models; Membrane Potentials; Neuroglia; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord Compression; Time Factors

2009
Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice.
    Epilepsia, 2009, Volume: 50, Issue:8

    Topics: Analgesics, Non-Narcotic; Animals; Carbenoxolone; Cerebral Cortex; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Female; Gap Junction delta-2 Protein; In Vitro Techniques; Magnesium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Seizures; Time Factors

2009
Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:9

    Topics: Animals; Carbenoxolone; Cell Communication; Connexin 43; Disease Models, Animal; Gap Junctions; Ischemic Contracture; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation

2009
Effect of central microinjection of carbenoxolone in an experimental model of focal cerebral ischemia.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:4

    Topics: Animals; Carbenoxolone; Cerebral Cortex; Disease Models, Animal; Dyskinesia, Drug-Induced; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Microinjections; Neostriatum; Rats; Rats, Wistar

2009
Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia.
    Neuron glia biology, 2010, Volume: 6, Issue:1

    Topics: Animals; Calcium; Calcium Signaling; Carbenoxolone; Cell Communication; Cells, Cultured; Disease Models, Animal; Electric Stimulation; Electrical Synapses; Female; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Physical Stimulation; Purinergic Antagonists; Suramin; Trigeminal Ganglion; Trigeminal Neuralgia

2010
Role of gap junctions in early brain injury following subarachnoid hemorrhage.
    Brain research, 2010, Feb-22, Volume: 1315

    Topics: Animals; Apoptosis; Blotting, Western; Brain; Brain Injuries; Carbenoxolone; Disease Models, Animal; Gap Junctions; Injections, Intraperitoneal; Male; Neuroprotective Agents; Octanols; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Subarachnoid Hemorrhage; Time Factors; Treatment Outcome

2010
Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.
    Journal of medicinal food, 2010, Volume: 13, Issue:1

    Topics: Alkylation; Animals; Anti-Ulcer Agents; Carbenoxolone; Cattle; Collagen; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Ethanol; Ethylmaleimide; Gastric Mucosa; Gastrins; Hydrolysis; Male; Milk Proteins; Mucus; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Swine; Whey Proteins

2010
Network oscillations in rod-degenerated mouse retinas.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin

2011
The effect of a gap-junction blocker, carbenoxolone, on ischemic brain injury and cortical spreading depression.
    Neuroscience, 2011, Oct-27, Volume: 194

    Topics: Animals; Anti-Ulcer Agents; Brain Infarction; Brain Ischemia; Carbenoxolone; Cerebrovascular Circulation; Cortical Spreading Depression; Disease Models, Animal; Gap Junctions; Male; Rats; Rats, Wistar

2011
[Microglia and neuronal degeneration].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Carbenoxolone; Cytokines; Disease Models, Animal; Drug Design; Glutamates; Humans; Microglia; Molecular Targeted Therapy; Multiple Sclerosis; Nerve Degeneration; Neurogenic Inflammation

2010
Interstitial volume modulates the conduction velocity-gap junction relationship.
    American journal of physiology. Heart and circulatory physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Action Potentials; Albumins; Animals; Anisotropy; Arrhythmias, Cardiac; Carbenoxolone; Cardiac Pacing, Artificial; Cell Size; Connexin 43; Disease Models, Animal; Disease Susceptibility; Edema, Cardiac; Electrocardiography; Gap Junctions; Guinea Pigs; Heart Conduction System; Heart Ventricles; Male; Mannitol; Perfusion; Phosphorylation; Time Factors; Ventricular Function, Left; Ventricular Function, Right; Voltage-Sensitive Dye Imaging

2012
Susceptibility of glucocorticoids to colonic metabolism and pharmacologic intervention in the metabolism: implication for therapeutic activity of colon-specific glucocorticoid 21-sulfate sodium at the target site.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:1

    Topics: Animals; Carbenoxolone; Chromatography, High Pressure Liquid; Colon; Disease Models, Animal; Drug Delivery Systems; Glucocorticoids; Glycyrrhizic Acid; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley

2012
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Duloxetine Hydrochloride; Electroshock; Exploratory Behavior; Fluoxetine; Food Deprivation; Food Preferences; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hormone Antagonists; Inhibition, Psychological; Isoquinolines; Male; Microscopy, Electron, Transmission; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiophenes

2012
Cardiac tissue slices with prolonged survival for in vitro drug safety screening.
    Journal of pharmacological and toxicological methods, 2012, Volume: 66, Issue:2

    Topics: 4-Aminopyridine; Action Potentials; Animal Testing Alternatives; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carbenoxolone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Piperidines; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Risk Assessment; Toxicity Tests

2012
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling.
    The Journal of physiology, 2012, May-01, Volume: 590, Issue:9

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Pressure; Brain Stem; Calcium; Carbenoxolone; Carbon Dioxide; Chemoreceptor Cells; Cobalt; Connexins; Denervation; Disease Models, Animal; Gap Junctions; Hydrogen-Ion Concentration; Hypercapnia; Male; Patch-Clamp Techniques; Phrenic Nerve; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic; Receptors, Purinergic P2Y1; Respiratory Center; Respiratory Mechanics; Signal Transduction; Suramin; Temperature; Time Factors

2012
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
    Nature medicine, 2012, Mar-25, Volume: 18, Issue:4

    Topics: Adenosine Triphosphate; Animals; Benzoxazoles; Calcium; Carbenoxolone; Cells, Cultured; Chronic Pain; Cohort Studies; Connexins; Disease Models, Animal; Enzyme Inhibitors; Female; Genetic Linkage; Genome-Wide Association Study; Genotype; Histidine; Humans; Hyperalgesia; Macrophages; Male; Mastectomy; Mice; Mice, Inbred Strains; Mutation; Nerve Tissue Proteins; Osteoarthritis; Pain Measurement; Pain Threshold; Peptides; Polymorphism, Single Nucleotide; Quinolinium Compounds; Receptors, Purinergic P2X7; Retrospective Studies; Species Specificity; Time Factors; Transfection

2012
Inhibition of intercellular coupling stabilizes spiral-wave reentry, whereas enhancement of the coupling destabilizes the reentry in favor of early termination.
    American journal of physiology. Heart and circulatory physiology, 2012, Sep-01, Volume: 303, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Carbenoxolone; Cell Communication; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Gap Junctions; Heart Conduction System; Oligopeptides; Perfusion; Rabbits; Tachycardia, Ventricular; Time Factors; Ventricular Fibrillation; Voltage-Sensitive Dye Imaging

2012
Antiulcerogenic activity of chlorogenic acid in different models of gastric ulcer.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carbenoxolone; Chlorogenic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Omeprazole; Stomach Ulcer; Time Factors

2013
Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion.
    Journal of medicinal food, 2002,Winter, Volume: 5, Issue:4

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Buthionine Sulfoximine; Carbenoxolone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Milk Proteins; Random Allocation; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Treatment Outcome; Whey Proteins

2002
Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice.
    BMC pharmacology, 2003, Apr-29, Volume: 3

    Topics: Animals; Anticonvulsants; Carbenoxolone; Disease Models, Animal; Electric Stimulation; Hypnotics and Sedatives; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Relaxants, Central; Seizures

2003
Desynchronisation of spontaneously recurrent experimental seizures proceeds with a single rhythm.
    Neuroscience, 2003, Volume: 121, Issue:3

    Topics: Animals; Animals, Newborn; Anti-Ulcer Agents; Calcium; Carbenoxolone; Cortical Synchronization; Disease Models, Animal; Evoked Potentials; Fluorometry; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Wistar; Seizures; Time Factors

2003
Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo.
    Epilepsia, 2003, Volume: 44, Issue:12

    Topics: 4-Aminopyridine; Animals; Carbenoxolone; Cerebral Cortex; Connexin 43; Connexins; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Gap Junction beta-1 Protein; Gap Junction delta-2 Protein; Gap Junctions; Gene Expression; Male; Methylamines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2003
Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice).
    Neuropharmacology, 2005, Volume: 49, Issue:4

    Topics: Animals; Autoradiography; Carbenoxolone; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Gene Expression Regulation; Male; Mice; Mice, Neurologic Mutants; Rats; Rats, Inbred Strains; Thalamic Nuclei; Time Factors

2005
Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Apoptosis; Brain; Carbenoxolone; Caspase 3; Caspases; Cell Communication; Connexins; Disease Models, Animal; DNA; Electrophysiology; Female; Gap Junctions; Glucose; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Ischemia; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nerve Degeneration; Neurons; Neuroprotective Agents; Nucleosomes; Oxygen; Polymerase Chain Reaction; Propidium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2005
Role of gap junctional coupling in astrocytic networks in the determination of global ischaemia-induced oxidative stress and hippocampal damage.
    The European journal of neuroscience, 2006, Volume: 23, Issue:1

    Topics: Animals; Astrocytes; Carbenoxolone; Cell Death; Disease Models, Animal; Electrodes; Electroencephalography; Evoked Potentials; Functional Laterality; Gap Junctions; Glycyrrhetinic Acid; Hippocampus; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lipid Peroxides; Male; Nerve Net; Oxidative Stress; Rats; Rats, Wistar; Time Factors

2006
Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional coupling.
    The European journal of neuroscience, 2006, Volume: 23, Issue:2

    Topics: Animals; Animals, Newborn; Brain Mapping; Carbenoxolone; Disease Models, Animal; Electrodes; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Functional Laterality; Gap Junctions; Methylamines; Rats; Rats, Long-Evans; Spectrum Analysis; Thalamus; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

2006
Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy.
    Epilepsy research, 2006, Volume: 69, Issue:1

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbenoxolone; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Gap Junctions; Potassium Channel Blockers; Rats; Rats, Inbred Strains; Rats, Wistar; Seizures; Sodium Chloride; Somatosensory Cortex; Thalamic Nuclei

2006
The lumbar spinal cord glial cells actively modulate subcutaneous formalin induced hyperalgesia in the rat.
    Neuroscience research, 2006, Volume: 55, Issue:4

    Topics: Afferent Pathways; Animals; Astrocytes; Biomarkers; Carbenoxolone; CD11b Antigen; Cell Communication; Citrates; Connexins; Disease Models, Animal; DNA-Binding Proteins; Gap Junctions; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Microglia; Nerve Tissue Proteins; Nociceptors; Nuclear Proteins; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley

2006
Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:10

    Topics: 1-Octanol; Animals; Carbenoxolone; Central Nervous System Stimulants; Cerebellum; Chloroquine; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Essential Tremor; Female; Gap Junction delta-2 Protein; Gap Junctions; Glycyrrhizic Acid; Harmaline; Heptanol; Injections, Subcutaneous; Mefloquine; Mice; Mice, Inbred ICR; Olivary Nucleus

2006
The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats.
    Epilepsia, 2006, Volume: 47, Issue:6

    Topics: 4-Aminopyridine; Animals; Animals, Newborn; Carbenoxolone; Connexins; Cortical Synchronization; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Epilepsy; Female; Gap Junctions; Gene Expression; Male; Methylamines; Neocortex; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures

2006
Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Administration, Topical; Animals; Anticonvulsants; Behavior, Animal; Carbenoxolone; Cerebral Cortex; Connexins; Disease Models, Animal; Drug Resistance; Electroencephalography; Electromyography; Gap Junctions; Infusion Pumps; Injections, Intralesional; Meclofenamic Acid; Rats; Rats, Sprague-Dawley; Seizures; Stereotaxic Techniques; Tetanus Toxin

2006
Anticonvulsive effects of carbenoxolone on penicillin-induced epileptiform activity: an in vivo study.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Animals; Anticonvulsants; Carbenoxolone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Epilepsy; Male; Penicillins; Rats; Rats, Wistar; Time Factors

2007
Blocking the glial function suppresses subcutaneous formalin-induced nociceptive behavior in the rat.
    Neuroscience research, 2007, Volume: 57, Issue:1

    Topics: Animals; Behavior, Animal; Carbenoxolone; Citrates; Disease Models, Animal; Drug Interactions; Fluorescent Antibody Technique; Formaldehyde; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Male; Microscopy, Immunoelectron; Neuroglia; Oncogene Proteins v-fos; Pain Measurement; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Skin; Trigeminal Neuralgia; Trigeminal Nuclei

2007
Satellite glial cells in sensory ganglia: their possible contribution to inflammatory pain.
    Brain, behavior, and immunity, 2007, Volume: 21, Issue:5

    Topics: Action Potentials; Animals; Carbenoxolone; Chi-Square Distribution; Disease Models, Animal; Female; Freund's Adjuvant; Ganglia, Spinal; Gap Junctions; Inflammation; Male; Mice; Mice, Inbred BALB C; Neuralgia; Neurons, Afferent; Pain Threshold; Satellite Cells, Perineuronal

2007
Pharmacological and toxicological studies of Drimys angustifolia Miers. (Winteraceae).
    Journal of ethnopharmacology, 2007, May-22, Volume: 111, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Carbenoxolone; Disease Models, Animal; Dose-Response Relationship, Drug; Drimys; Female; Inflammation; Male; Mice; Nitric Oxide; Oxidative Stress; Pain; Pain Measurement; Phytotherapy; Plant Bark; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Stomach Ulcer

2007
Glucocorticoid availability in colonic inflammation of rat.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Budesonide; Carbenoxolone; Colitis; Colon; Corticosterone; Cyclooxygenase 2; Disease Models, Animal; Glucocorticoids; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Mucin-2; Mucins; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2008
Inhibitory effect of gap junction blockers on cerebral vasospasm.
    Journal of neurosurgery, 2008, Volume: 108, Issue:3

    Topics: Animals; Basilar Artery; Carbenoxolone; Disease Models, Animal; Gap Junctions; Heptanol; Rabbits; Subarachnoid Hemorrhage; Tissue Culture Techniques; Vasoconstriction; Vasospasm, Intracranial

2008
Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling.
    Neuroscience, 2001, Volume: 105, Issue:3

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Anti-Ulcer Agents; Carbenoxolone; Cell Communication; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Gap Junctions; Halothane; Hippocampus; Magnesium; Magnesium Deficiency; Male; Methylamines; Octanols; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2001
A neuroprotective role for gap junctions.
    Cell communication & adhesion, 2001, Volume: 8, Issue:4-6

    Topics: Animals; Astrocytes; Brain Ischemia; Carbenoxolone; Cell Communication; Cells, Cultured; Central Nervous System; Coculture Techniques; Connexin 43; Disease Models, Animal; Gap Junctions; Glutamic Acid; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; Neurons

2001
Cimetidine, carbenoxolone sodium, and antacids for the prevention of experimental stress ulcers.
    Archives of surgery (Chicago, Ill. : 1960), 1978, Volume: 113, Issue:7

    Topics: Animals; Antacids; Carbenoxolone; Cimetidine; Disease Models, Animal; Drug Therapy, Combination; Electrophysiology; Gastric Mucosa; Guanidines; Humans; Hydrogen-Ion Concentration; Male; Rats; Stomach Ulcer; Stress, Psychological; Triterpenes

1978
Effects of carbenoxolone Na on acute and chronic gastric ulcer models in experimental animals.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:8

    Topics: Acute Disease; Animals; Aspirin; Carbenoxolone; Chronic Disease; Disease Models, Animal; Dogs; Gastric Juice; Guinea Pigs; Histamine; Humans; Ligation; Male; Pylorus; Rats; Serotonin; Stomach Ulcer; Stress, Psychological; Triterpenes

1976