| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| AID752426 | Selectivity ratio of IC50 for sigma2 receptor (unknown origin) to IC50 for sigma1 receptor (unknown origin) | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752408 | Toxicity in rat at 1600 mg/kg, po up to 120 mins | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752412 | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752415 | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 1 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752424 | Binding affinity to M3 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752427 | Binding affinity to sigma2 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752413 | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 100 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752409 | Half life in rat liver microsomes | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752411 | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in MDR1 transfected dog MDCK cells | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752420 | Cytotoxicity against cortical neuron (unknown origin) at 10 uM | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752414 | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 10 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752417 | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 10 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752425 | Binding affinity to M1 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752421 | Binding affinity to M5 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752422 | Binding affinity to M4 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752416 | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 100 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752407 | Drug excretion in human urine after 24 hrs | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752410 | Ratio of drug level in brain to plasma in rat at 1600 mg/kg, po after 120 mins | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752428 | Binding affinity to sigma1 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752418 | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 1 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| AID752423 | Binding affinity to M2 receptor (unknown origin) by radioligand displacement assay | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |