An inhibitor that interferes with vesicular glutamate transport.
ChEBI ID: 72483
| Member | Definition | Class |
|---|---|---|
| xanthurenic acid | A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by hydroxy groups at C-4 and C-8. | xanthurenic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 93 (33.45) | 18.7374 |
| 1990's | 42 (15.11) | 18.2507 |
| 2000's | 50 (17.99) | 29.6817 |
| 2010's | 78 (28.06) | 24.3611 |
| 2020's | 15 (5.40) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 5 (1.69%) | 5.53% |
| Reviews | 8 (2.71%) | 6.00% |
| Case Studies | 4 (1.36%) | 4.05% |
| Observational | 2 (0.68%) | 0.25% |
| Other | 276 (93.56%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 13.8914 | 1 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 9.9763 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 79.4328 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Vesicular glutamate transporter 3 | Rattus norvegicus (Norway rat) | Ki | 190.0000 | 1 | 1 |