An arginine derivative that is arginine substituted by two methyl groups. A "closed" class.
ChEBI ID: 86468
| Member | Definition | Role |
|---|---|---|
| n,n-dimethylarginine | A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group. | N(omega),N(omega)-dimethyl-L-arginine |
| symmetric dimethylarginine | A L-arginine derivative having two methyl groups at the N(omega)- and N'(omega)-positions | N(omega),N'(omega)-dimethyl-L-arginine zwitterion; N(omega),N'(omega)-dimethyl-L-arginine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 11 (0.48) | 18.7374 |
| 1990's | 61 (2.64) | 18.2507 |
| 2000's | 733 (31.75) | 29.6817 |
| 2010's | 1,285 (55.65) | 24.3611 |
| 2020's | 219 (9.48) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 255 (9.64%) | 5.53% |
| Reviews | 278 (10.51%) | 6.00% |
| Case Studies | 7 (0.26%) | 4.05% |
| Observational | 40 (1.51%) | 0.25% |
| Other | 2,064 (78.06%) | 84.16% |