Chemical Sensitivities, Multiple

An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)

Synonym
Idiopathic Environmental Intolerances
Idiopathic Environmental Intolerance
Multiple Chemical Sensitivities
Chemical Sensitivities, Multiple
Multiple Chemical Sensitivity
Sensitivities, Multiple Chemical
Chemical Sensitivity, Multiple
Multiple Chemical Sensitivity Syndrome
Sensitivity, Multiple Chemical

Excerpt	Reference
"Multiple chemical sensitivity is a controversial diagnosis."	( Eissenberg, T; Griffiths, RR, 1997)
"Multiple chemical sensitivity is a poorly understood syndrome in which various symptoms are triggered by chemically unrelated, but often odorous substances, at doses below those known to be harmful."	( Eelen, P; Nemery, B; Raes, C; Stegen, K; Stulens, P; Van de Woestijne, KP; Van den Bergh, O; Van Diest, I; Veulemans, H, 1999)
"The syndrome of multiple chemical sensitivities is controversial subject with increasing impact on the field of indoor air quality."	( Ando, M, 2002)
"Multiple chemical sensitivity syndrome is a group of complex disorders that include psychiatric disorders, chronic fatigue and/or respiratory problems."	( Álvarez López, JC; Fernández Martín, MT, 2018)

Excerpt	Reference
"A 53-year-old man with multiple chemical sensitivities (MCS) received the selective serotonin reuptake inhibitor (SSRI) citalopram for treatment of depression."	( Andiné, P; Järvholm, B; Rönnbäck, L, 1997)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	26 (20.00)	12.5806
2000's	70 (53.85)	18.1394
2010's	32 (24.62)	28.8240
2020's	2 (1.54)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	low	1	0
dinitrochlorobenzene	low	1	0
ammonium hydroxide	medium	3	1
benzene	low	1	0
1-butanol	medium	3	2
butyric acid	medium	2	1
carbon monoxide	low	2	0
methane	medium	1	1
hydrogen sulfide	medium	1	1
formaldehyde	medium	12	1
histamine	low	1	0
methanol	low	1	0
nickel	medium	4	1
nitrates	low	2	0
nitric acid	low	1	0
pentachlorophenol	low	1	0
1-propanol	medium	1	1
pyridine	medium	2	1
toluene	medium	6	1
uracil	low	1	0
amoxapine	low	1	0
aspirin	low	1	0
benzamide	low	1	0
benzo(a)pyrene	low	1	0
caffeine	low	2	0
citalopram	low	2	0
haloperidol	low	1	0
lidocaine	medium	2	1
2-propanol	low	1	0
mexiletine	low	1	0
deet	low	2	0
piracetam	low	1	0
sevoflurane	low	1	0
thiram	low	1	0
corticosterone	low	1	0
prednisone	low	1	0
sucrose	low	1	0
phenylethyl alcohol	medium	2	1
methacholine chloride	low	2	0
carbaryl	low	1	0
chloroform	low	1	0
n-pentanol	low	2	0
arginine	low	1	0
vinyl chloride	low	1	0
phencyclidine	low	3	0
methylethyl ketone	low	2	0
quinoline	low	1	0
2-naphthylamine	low	1	0
ethylbenzene	low	3	0
pyridostigmine bromide	low	1	0
3-xylene	low	1	0
framycetin	low	1	0
thiazoles	low	1	0
ephedrine	low	1	0
trimellitic anhydride	low	2	0
toluene 2,4-diisocyanate	low	2	0
amyl acetate	low	1	0
methyl tert-butyl ether	low	1	0
methylprednisolone hemisuccinate	low	1	0
n-methylaspartate	low	4	0
mercury	low	3	0
palladium	low	2	0
xenon	low	1	0
palladium chloride	low	1	0
potassium dichromate	low	2	0
nickel sulfate	low	2	0
ozone	medium	3	1
radon	low	1	0
cromolyn sodium	low	1	0
phenyl acetate	medium	3	1
butyl acetate	medium	2	1
isoamyl acetate	low	1	0
2,4,5,2',4',5'-hexachlorobiphenyl	low	1	0
triadimefon	low	1	0
2-methyl-4-isothiazolin-3-one	low	1	0
permethrin	low	2	0
paroxetine	low	1	0
cefaclor anhydrous	low	1	0
fomesafen	low	2	0
3,4,5,3',4'-pentachlorobiphenyl	low	1	0
peroxynitric acid	low	1	0
cephalosporin c	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	3	0
galaxolide	medium	1	1
homocysteine	low	1	0
cobalt	low	2	0
vitamin b 6	low	1	0
peroxynitrous acid	low	4	0
carbocysteine	low	1	0
cortisone	low	1	0
cyanoginosin lr	low	1	0
cocaine	low	3	0
mupirocin	low	1	0
capsaicin	medium	17	5
cobaltous chloride	low	2	0
nitrogen dioxide	low	2	0
ovalbumin	low	1	0
levetiracetam	low	1	0
morphine	low	1	0
aluminum	low	1	0
sulfur	low	1	0
dizocilpine maleate	low	1	0
cholecystokinin	low	1	0
beta-endorphin	medium	1	1
sodium lactate	low	2	0
salicylates	medium	1	1
pyrethrins	low	3	0
vitamin b 12	low	1	0
tixocortol	low	1	0
folic acid	low	1	0
neopterin	medium	2	1
clozapine	low	1	0
eye	medium	3	1
ego	low	1	0

Protein Targets (1,132)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	17	0	0	17
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
glucocorticoid receptor [Homo sapiens]	27	0	0	27
farnesoid X nuclear receptor	16	0	0	16
estrogen nuclear receptor alpha	44	0	0	44
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Cellular tumor antigen p53	20	0	0	20
Glutamate receptor 2	15	1	0	16
Choline O-acetyltransferase	0	1	0	2
euchromatic histone-lysine N-methyltransferase 2	26	0	0	26
Bloom syndrome protein isoform 1	10	0	0	10
peripheral myelin protein 22 isoform 1	8	0	0	8
D(1A) dopamine receptor	7	0	0	7
lamin isoform A-delta10	17	0	0	17
Glutamate receptor 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	11	1	14
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	11	1	14
Glutamate receptor ionotropic, NMDA 2B	0	11	1	14
Glutamate receptor ionotropic, NMDA 2C	0	11	1	15
Glutamate receptor ionotropic, NMDA 2D	0	11	1	14
Glutamate receptor ionotropic, NMDA 3B	0	11	1	14
Glutamate receptor ionotropic, NMDA 3A	0	11	1	14
ATP-dependent phosphofructokinase	11	0	0	11
thioredoxin reductase	20	0	0	20
nonstructural protein 1	4	0	0	4
arylsulfatase A	6	0	0	6
thyroid hormone receptor beta isoform a	15	0	0	15
histone acetyltransferase KAT2A isoform 1	9	0	0	9
neuropeptide S receptor isoform A	3	0	0	3
Luciferase	14	0	0	14
acetylcholinesterase	10	0	0	10
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
RAR-related orphan receptor gamma	36	0	0	36
SMAD family member 2	8	0	0	8
SMAD family member 3	8	0	0	8
GLI family zinc finger 3	31	0	0	31
AR protein	34	0	0	34
nuclear receptor subfamily 1, group I, member 3	25	0	0	25
retinoic acid nuclear receptor alpha variant 1	32	0	0	32
retinoid X nuclear receptor alpha	24	0	0	24
estrogen-related nuclear receptor alpha	33	0	0	33
pregnane X nuclear receptor	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	19	0	0	19
Histone H2A.x	12	0	0	12
Chain A, HADH2 protein	16	0	0	16
Chain B, HADH2 protein	16	0	0	16
ClpP	1	0	0	1
pregnane X receptor	9	0	0	9
apical membrane antigen 1, AMA1	6	0	0	6
estrogen receptor 2 (ER beta)	14	0	0	14
regulator of G-protein signaling 4	7	0	0	7
aryl hydrocarbon receptor	12	0	0	12
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
thyroid hormone receptor beta isoform 2	24	0	0	24
nuclear factor erythroid 2-related factor 2 isoform 1	33	0	0	33
cytochrome P450 3A4 isoform 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit pi	15	3	0	18
Neutrophil cytosol factor 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	15	3	0	18
Gamma-aminobutyric acid receptor subunit delta	15	3	0	18
Gamma-aminobutyric acid receptor subunit gamma-2	15	3	0	18
Gamma-aminobutyric acid receptor subunit alpha-5	15	3	0	18
Gamma-aminobutyric acid receptor subunit alpha-3	15	3	0	18
Gamma-aminobutyric acid receptor subunit gamma-1	15	3	0	18
Gamma-aminobutyric acid receptor subunit alpha-2	15	3	0	18
Gamma-aminobutyric acid receptor subunit alpha-4	15	3	0	18
Gamma-aminobutyric acid receptor subunit gamma-3	15	3	0	18
Gamma-aminobutyric acid receptor subunit alpha-6	15	3	0	18
Nuclear receptor ROR-gamma	14	0	0	14
Gamma-aminobutyric acid receptor subunit alpha-1	15	4	0	19
Gamma-aminobutyric acid receptor subunit beta-3	15	3	0	18
Guanine nucleotide-binding protein G	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-2	15	3	0	18
GABA theta subunit	15	3	0	18
Gamma-aminobutyric acid receptor subunit epsilon	15	3	0	18
peroxisome proliferator-activated receptor delta	19	0	0	19
activating transcription factor 6	13	0	0	13
heat shock protein beta-1	13	0	0	13
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
progesterone receptor	25	0	0	25
peroxisome proliferator activated receptor gamma	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
thyroid stimulating hormone receptor	14	0	0	14
chromobox protein homolog 1	20	0	0	20
mitogen-activated protein kinase 1	8	0	0	8
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
geminin	28	0	0	28
lethal factor (plasmid)	13	0	0	13
Cytochrome P450 1A1	0	0	2	2
Aryl hydrocarbon receptor	0	0	3	3
Rap guanine nucleotide exchange factor 4	3	0	0	3
glucocerebrosidase	6	0	0	6
Endolysin	0	0	4	4
Acetylcholinesterase	0	7	0	7
Cytochrome P450 1B1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
Chain A, Beta-lactamase	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
Chain A, Ferritin light chain	6	0	0	6
endonuclease IV	5	0	0	5
Fumarate hydratase	4	0	0	4
USP1 protein, partial	7	0	0	7
NFKB1 protein, partial	6	0	0	6
GLS protein	15	0	0	15
TDP1 protein	24	0	0	24
Thrombopoietin	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
thyroid stimulating hormone receptor	19	0	0	19
isocitrate dehydrogenase 1, partial	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	10	0	0	10
EWS/FLI fusion protein	8	0	0	8
cytochrome P450 2D6	11	0	0	11
polyprotein	4	0	0	4
67.9K protein	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
cytochrome P450 2D6 isoform 1	4	0	0	4
cellular tumor antigen p53 isoform a	6	0	0	6
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
vitamin D3 receptor isoform VDRA	7	0	0	7
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
peripheral myelin protein 22	11	0	0	11
survival motor neuron protein isoform d	10	0	0	10
M-phase phosphoprotein 8	7	0	0	7
transient receptor potential cation channel subfamily V member 1	4	0	0	4
muscarinic acetylcholine receptor M1	10	0	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
ATP-binding cassette sub-family C member 3	0	13	0	13
Multidrug resistance-associated protein 4	0	13	0	14
5-hydroxytryptamine receptor 4	0	8	0	8
Bile salt export pump	0	21	0	21
Aldo-keto reductase family 1 member B1	0	10	0	10
Muscarinic acetylcholine receptor M2	0	7	1	8
Muscarinic acetylcholine receptor M4	0	7	1	8
5-hydroxytryptamine receptor 1A	0	5	1	6
Muscarinic acetylcholine receptor M5	0	8	0	8
Alpha-2A adrenergic receptor	0	6	1	7
Cytochrome P450 2D6	0	3	0	4
Muscarinic acetylcholine receptor M1	0	8	1	9
D(2) dopamine receptor	0	7	1	13
Alpha-2B adrenergic receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	6	0	6
Muscarinic acetylcholine receptor M3	0	7	1	8
D(1A) dopamine receptor	0	6	0	8
D(4) dopamine receptor	0	5	1	10
Sodium-dependent noradrenaline transporter	0	12	1	13
Alpha-1D adrenergic receptor	0	8	0	8
5-hydroxytryptamine receptor 2A	0	7	0	9
5-hydroxytryptamine receptor 2C	0	8	1	9
Sodium-dependent serotonin transporter	0	12	2	14
5-hydroxytryptamine receptor 7	0	3	0	3
Histamine H1 receptor	0	11	4	17
D(3) dopamine receptor	0	6	1	11
5-hydroxytryptamine receptor 2B	0	10	1	11
Histamine H2 receptor	4	0	1	6
D(1A) dopamine receptor	3	1	0	4
Sulfotransferase 1A1	0	1	0	1
5-hydroxytryptamine receptor 6	0	5	0	6
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Inositol monophosphatase 1	3	0	0	3
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sulfotransferase 2A1	0	1	0	1
TAR DNA-binding protein 43	11	0	0	11
Canalicular multispecific organic anion transporter 1	0	13	0	13
Ataxin-2	11	0	0	11
Histamine H4 receptor	0	4	3	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	9	0	0	9
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	6	0	0	6
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	14	0	0	14
Cytochrome P450 3A4	0	5	2	10
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	5	0	0	5
hypothetical protein, conserved	2	0	0	2
Rac1 protein	0	0	1	1
IDH1	10	0	0	10
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase kappa isoform 1	4	0	0	4
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	4	2	7
Carbonic anhydrase 1	0	6	0	7
Carbonic anhydrase 2	0	8	1	11
Fatty acid-binding protein, liver	0	1	0	1
Integrin beta-3	3	1	0	4
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	3	1	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Adenosine receptor A1	0	5	0	7
Adenosine receptor A2a	0	3	0	6
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	12	1	13
Sigma non-opioid intracellular receptor 1	0	6	1	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Microtubule-associated protein tau	10	0	0	10
DNA polymerase beta	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Nicotinamide N-methyltransferase	0	2	0	2
Poly(ADP-ribose) glycohydrolase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
acid sphingomyelinase	2	0	0	2
glp-1 receptor, partial	10	0	0	10
Smad3	4	0	0	4
caspase 7, apoptosis-related cysteine protease	6	0	0	6
caspase-3	6	0	0	6
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Cytochrome P450 1A2	0	2	0	2
Tyrosine-protein kinase Fyn	0	1	1	2
Amine oxidase [flavin-containing] A	0	2	0	2
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Histone deacetylase 3	0	3	0	3
Histone deacetylase 4	0	3	0	3
Histone deacetylase 1	0	3	0	3
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	10	0	0	10
Potassium channel subfamily K member 2	0	3	1	4
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Adenosine receptor A3	0	1	0	1
Replicase polyprotein 1ab	0	3	1	4
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	1	4
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	1	1	4
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Guanine deaminase	0	1	0	1
15-lipoxygenase, partial	4	0	0	4
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
Spike glycoprotein	12	0	1	13
D(2) dopamine receptor	0	5	1	6
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
kallikrein-5 preproprotein	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Acetylcholinesterase	0	2	0	2
Interferon beta	8	0	0	8
Kinesin-like protein KIF11	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
serine/threonine-protein kinase PLK1	4	0	0	4
DNA polymerase eta isoform 1	1	0	0	1
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
streptokinase A precursor	0	0	2	2
Estrogen receptor	0	0	2	2
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 15 member 2	0	1	0	1
Estrogen receptor beta	0	0	2	2
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
PINK1	2	0	0	2
Parkin	3	0	0	3
Caspase-7	1	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
prostaglandin E2 receptor EP2 subtype	0	0	0	1
caspase-3	1	0	0	1
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
ORF73	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
Solute carrier family 22 member 1	0	5	0	6
Sodium-dependent noradrenaline transporter	0	2	0	2
Tryptophan 5-hydroxylase 1	0	2	0	2
Angiotensin-converting enzyme	0	7	0	7
Aldo-keto reductase family 1 member B1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	7	0	7
Aromatase	0	1	0	1
Sodium-dependent dopamine transporter	0	8	0	8
Sodium-dependent serotonin transporter	0	9	1	11
5-hydroxytryptamine receptor 7	0	3	0	3
Sodium-dependent dopamine transporter	0	6	1	7
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Sigma intracellular receptor 2	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	4	0	4
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
Transporter	0	7	0	7
5-hydroxytryptamine receptor 3E	0	1	0	1
ATAD5 protein, partial	8	0	0	8
G	6	0	0	6
Beta-1 adrenergic receptor	0	1	0	1
Adenylate cyclase type 1	0	2	0	2
cytochrome P450 2C9 precursor	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Bile salt export pump	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Albumin	0	0	2	2
ATP-dependent translocase ABCB1	0	4	0	6
Muscarinic acetylcholine receptor M1	0	6	1	7
Muscarinic acetylcholine receptor M3	0	5	1	6
Muscarinic acetylcholine receptor M4	0	5	1	6
5-hydroxytryptamine receptor 2C	0	6	0	6
Muscarinic acetylcholine receptor M5	0	5	1	6
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M2	0	5	1	6
Cytochrome P450 2C9	0	4	0	5
5-hydroxytryptamine receptor 2A	0	6	0	6
Alpha-1B adrenergic receptor	0	5	1	6
Beta-1 adrenergic receptor	0	2	0	2
D	0	5	0	5
D(3) dopamine receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	5	1	6
D(2) dopamine receptor	0	4	0	4
Endothelin receptor type B	0	1	0	1
D(1B) dopamine receptor	0	3	0	5
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	5	1	6
UDP-glucuronosyltransferase 1A4	0	0	0	2
Alpha-2A adrenergic receptor	0	5	1	6
Alpha-1D adrenergic receptor	0	5	1	6
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	5	2	7
D(1B) dopamine receptor	0	4	0	4
Beta-3 adrenergic receptor	0	2	0	2
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 1B	0	4	0	4
5-hydroxytryptamine receptor 1D	0	4	0	4
D(4) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 1F	0	4	0	4
5-hydroxytryptamine receptor 2B	0	6	1	7
Histamine H1 receptor	0	2	2	4
Histamine H1 receptor	0	6	1	7
5-hydroxytryptamine receptor 7	0	3	0	3
Cytochrome P450 2C19	0	0	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
Adenylate cyclase type 8	0	2	0	2
Alpha-1A adrenergic receptor	0	5	1	6
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Cytochrome P450 2J2	0	4	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Calmodulin	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
5-hydroxytryptamine receptor 2B	0	2	0	2
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Adenylyl cyclase 7	0	2	0	2
5-hydroxytryptamine receptor 3C	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
D	0	3	0	3
ATPase family AAA domain-containing protein 5	9	0	0	9
5-hydroxytryptamine receptor 3B	0	2	0	2
Histamine H3 receptor	0	2	2	4
cytochrome P450 2C9, partial	6	0	0	6
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Liver carboxylesterase 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
GALC protein	4	0	0	4
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 3	0	2	0	3
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	0	1	1
Androgen receptor	0	1	0	1
C-8 sterol isomerase	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	3	0	4
dopamine D1 receptor	1	0	0	1
Glucocorticoid receptor	0	6	1	7
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Multidrug and toxin extrusion protein 1	0	2	0	2
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Protein phosphatase 1A	0	1	0	1
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	0	1	0	1
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	1
Chain A, Odorant binding protein	0	0	1	1
Chain B, Odorant binding protein	0	0	1	1
thioredoxin glutathione reductase	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
Vpr	4	0	0	4
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase omega-1	0	1	0	1
pyruvate kinase	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Alpha-synuclein	4	0	0	4
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Cocaine esterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Major prion protein	0	0	1	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Delta-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	7
Kappa-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	4	2	7
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	3
Kappa-type opioid receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	4	0	4
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	0	0	1
Plasma kallikrein	0	0	0	1
Carbonic anhydrase 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Carbonic anhydrase 4	0	4	0	5
Carbonic anhydrase 6	0	2	0	3
5-hydroxytryptamine receptor 1D	0	0	0	1
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
Carbonic anhydrase	0	3	0	4
Carbonic anhydrase 7	0	2	0	3
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	4	1	6
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	2	0	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Carbonic anhydrase 14	0	0	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
Potassium channel subfamily K member 3	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
thyrotropin-releasing hormone receptor	3	0	0	3
galanin receptor type 3	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	1	0	3
Kappa-type opioid receptor	0	2	1	5
UDP-glucuronosyltransferase 1A3	0	0	0	1
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	6
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, Isoleucyl-tRNA synthetase	0	1	0	1
heat shock protein 90	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Isoleucine--tRNA ligase	0	1	0	1
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
PPM1D protein	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	2	1	3
Tyrosine-protein kinase Lck	0	0	1	1
Cyclin-dependent kinase 1	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	2	1	3
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	1	0	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	2	3
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
von Hippel-Lindau disease tumor suppressor	0	1	0	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Dipeptidyl peptidase 1	0	1	0	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
Epidermal growth factor receptor	0	2	0	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	0	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
ALK tyrosine kinase receptor	0	1	1	2
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Envelope glycoprotein	0	0	1	1
Rhodopsin kinase GRK1	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
Chain C, Respiratory nitrate reductase 1 gamma chain	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Pentachlorophenol 4-monooxygenase	0	0	1	1
ATP phosphoribosyltransferase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
beta-2 adrenergic receptor	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Hsf1 protein	0	0	1	2
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
huntingtin isoform 2	1	0	0	1
E3 ubiquitin-protein ligase Mdm2 isoform a	0	0	1	1
pyruvate kinase PKM isoform a	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Gamma-butyrobetaine dioxygenase	0	1	1	2
Retinal dehydrogenase 1	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Substance-K receptor	0	0	1	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Monoglyceride lipase	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
heat shock protein 90, putative	0	0	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Cytochrome P450 14alpha-demethylase	0	0	1	1
Skn7p	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Protein cereblon	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Chemical Sensitivities, Multiple

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (130)

Protein Targets (1,132)

Chemical Sensitivities, Multiple

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (130)

Drugs Studied (131)

Protein Targets (1,132)