Page last updated: 2024-09-27

Primary Hyperparathyroidism

Synonyms(1)

Synonym
Primary Hyperparathyroidism

Research Excerpts

Overview

ExcerptReference
"Primary hyperparathyroidism is the leading cause of hypercalcemia in the United States."( Chen, H; Ibele, A; Kabbani, L; Murphy, J; Weigel, TL, 2005)
"When a diagnosis of primary hyperparathyroidism is made but the localization of adenoma(s) is not identified, the patient should be referred to specialists for parathyroid surgery."( Sato, K, 2005)
"Primary hyperparathyroidism is characterized by hypercalcemia with loss of bone mass."( Kuo, SW; Lee, IT; Pei, D; Sheu, WH; Tu, ST, 2006)
"Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient setting and is typically caused by a single benign parathyroid adenoma."( Farford, B; Moraghan, TJ; Presutti, RJ, 2007)
"Primary hyperparathyroidism is a rare cause of chronic pancreatitis and there is a paucity of data on this interesting association."( Bhadada, SK; Bhansali, A; Bhasin, DK; Rana, SS; Sinha, SK; Udawat, HP, 2008)
"Sporadic primary hyperparathyroidism is due to single adenoma in over 90-95% of instances."( Membrilla, E; Rosa, P; Sancho, JJ; Sitges-Serra, A; Valero, M, 2008)
"Primary hyperparathyroidism is a curable cause of a Creutzfeldt-Jakob like syndrome."( Chadenat, ML; D'Anglejean, J; Dalloz, MA; Fineyre, F; Pico, F, 2009)
"Primary hyperparathyroidism is a rare but potentially life-threatening side effect of long-term lithium therapy."( Perrier, ND; Rizwan, MM, 2009)
"Most patients with primary hyperparathyroidism are asymptomatic, and the focus of the presentation may be the side effects of chronic hypercalcemia, osteoporosis, renal lithiasis, peptic ulcer disease, and hypertension."( Dora, JM; Maia, AL; Meyer, EL; Puñales, MK; Siqueira, DR, 2008)
"Primary hyperparathyroidism is a common cause of hypercalcemia with resulting hypercalciuria and a subset of these patients with primary hyperparathyroidism present with urolithiasis."( Berger, AD; Cooperberg, MR; Duh, QY; Eisner, BH; Stoller, ML; Wu, W, 2009)
"Primary hyperparathyroidism is nowadays frequently diagnosed from screening biological work-up: it is due to a single parathyroid adenoma in nearly 90% of cases."( Richard, B, 2009)
"Primary hyperparathyroidism is an important factor in the development of electrocardiographic abnormalities in this population, some of which are not corrected after parathyroidectomy."( Asensio-Lafuente, E; Castillo-Martínez, L; Orea-Tejeda, A; Orozco-Gutiérrez, JJ; Rebollar-González, V; Reza-Albarrán, A; Silva-Tinoco, R; Vázquez-Díaz, O, 2009)
"Primary hyperparathyroidism is the third most common endocrine disorder, with the highest incidence in postmenopausal women."( Fraser, WD, 2009)
"Primary hyperparathyroidism is caused by an adenoma/hyperplasia in the parathyroid glands in which hypercalcemia is mainly due to an increased secretion of parathormone (PTH)."( Alameda Hernando, C; Díaz Guardiola, P; Guijarro de Armas, G; Iglesias Bolaños, P; Pavón de Paz, I; Vega Piñero, B, 2009)
"Primary hyperparathyroidism is a common cause of hypercalcemia in dogs."( Goldstein, RE; Schaefer, C, 2009)
"Primary hyperparathyroidism is associated with an increased cardiovascular morbidity and mortality."( Alrasheedi, S; Ayav, A; Bresler, L; Brunaud, L; Caillard, C; Germain, A; Mirallie, E; Rancier, M; Weryha, G; Zarnegar, R, 2009)
"Primary hyperparathyroidism is commonly due to a single, sporadic parathyroid adenoma, and surgery is considered the treatment of choice based on guidelines established by the National Institutes of Health consensus panel."( Padmanabhan, H, 2010)
"Primary hyperparathyroidism is a common disorder that involves the pathological enlargement of one or more parathyroid glands resulting in excessive production of parathyroid hormone (PTH)."( Agha, A; Davenport, C, 2009)
"Primary hyperparathyroidism is a common disorder of mineral metabolism characterized by incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands."( Bilezikian, JP; Silverberg, SJ, 2010)
"Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient setting."( Felger, EA; Kandil, E, 2010)
"Primary hyperparathyroidism is one of the most common causes of hypercalcemia."( Chang, YC; Cheng, SP; Doherty, GM; Liu, CL, 2011)
"Primary hyperparathyroidism is a common endocrine disease."( Quinkler, M; Ventz, M, 2010)
"Primary hyperparathyroidism is rare in children."( Carpenter, TO; Cheng, DW; Udelsman, RD; Vanstone, MB, 2011)
"Main message Primary hyperparathyroidism is the most common cause of hypercalcemia in outpatients."( Khan, A; Pallan, S, 2011)
"Primary hyperparathyroidism is systemic, polymorphic disease."( Adamkiewicz, K; Mazur, J; Podwińska, E; Skorupa, A; Turek, S; Ziółko, E, 2011)
"Patients with primary hyperparathyroidism are eligible for outpatient surgery if the risk of conducting the operation is low and various imaging techniques have confirmed the location of the parathyroid adenoma."( de Herder, WW; Geilvoet, W; van Eijck, CH; van Ginhoven, TM, 2012)
"Normocalcemic primary hyperparathyroidism is at present one of the most common reasons for consultation in bone metabolism units."( Guadalix Iglesias, S; Hawkins Carranza, F; Martínez Díaz-Guerra, G, 2013)
"Normocalcemic primary hyperparathyroidism is typically identified after referral to a specialty clinic."( Bauer, DC; Bilezikian, JP; Cremers, SC; Cusano, NE; Haney, EM; Maalouf, NM; Orwoll, ES; Wang, PY; Zhang, C, 2013)
"Sixteen percent of primary hyperparathyroidism is caused by ectopic parathyroid glands."( Kajdácsi, Z; Mészáros, L; Révai, T; Tóth, M; Vadász, P, 2013)
"Primary hyperparathyroidism is a rare cause of acute pancreatitis."( Abraham, D; Augustine, J; Chandramohan, A; Chowdhury, SD; Dutta, AK; Hephzibah, J; Jeyaraj, V; Joseph, AJ; Kurien, RT; Pal, S; Simon, EG, 2014)
"Primary hyperparathyroidism is a common endocrinopathy which is nowadays diagnosed incidentally."( Antonucci, G; Catrambone, U; Foppiani, L; Lione, S; Lo Pinto, G; Marinaro, E; Piccardo, A; Scirocco, MC, 2014)
"Primary hyperparathyroidism is characterised by high parathyroid hormone (PTH) levels and concomitant hypercalcaemia."( Musters, L; Smit, C; van Ginhoven, TM, 2014)
"Primary hyperparathyroidism is a complex disease process that requires careful diagnosis and thoughtful medical and surgical management."( Callender, GG; Udelsman, R, 2014)
"Primary hyperparathyroidism is a common endocrine disorder which is diagnosed biochemically and for which therapy is surgical."( Fettich, J; Hocevar, M; Kocjan, T; Lezaic, L; Rep, S; Sever, MJ, 2014)
"Primary hyperparathyroidism is the main endocrinopathy associated with Multiple Endocrine Neoplasia type 1 syndrome."( Brandi, ML; Cianferotti, L; Cioppi, F; Colao, A; Faggiano, A; Ferolla, P; Giusti, F; Gronchi, G; Masi, L, 2016)
"Primary hyperparathyroidism is well known to be associated with cardiovascular morbidity and mortality."( Altuntas, Y; Canat, MM; Dogan Cakir, S; Erol, S; Karatas, S; Kuzu, I; Yener Ozturk, F, 2016)
"Primary hyperparathyroidism is a medical condition caused by overactive of parathyroid gland."( Harbuwono, DS; Larasati, D; Pramono, LA; Soebardi, S; Yossy, Y, 2015)
"Primary hyperparathyroidism is a rare disease characterized by excessive secretion of parathyroid hormone from parathyroid adenoma, hyperplasia, or malignancy."( Hayashi, S; Ishibashi, K; Kitada, M; Nana, T; Okazaki, S; Yasuda, S, 2016)
"Primary hyperparathyroidism is a disease with increased cell proliferation and enhanced PTH secretion due to the escape from negative feedback by calcium ion in parathyroid cells for their tumorization."( Kaji, H, 2016)
"Primary hyperparathyroidism is a common endocrine disorder that results in elevated levels of parathyroid hormone and subsequent hypercalcaemia."( Walker, J, 2016)
"Primary hyperparathyroidism is the most common manifestation of multiple endocrine neoplasia type 1 (MEN1)."( Beninato, T; Drake, FT; Duh, QY; Gosnell, J; Kluijfhout, WP; Liu, C; Shen, WT; Suh, I; Vriens, MR, 2016)
"Patients with primary hyperparathyroidism are characterized by increased calcium plasma concentrations, which in turn could have a potential to induce ECG changes, especially shortening of the QT interval."( Dokupilova, A; Payer, J, 2016)
"Primary hyperparathyroidism is characterized by increased levels of serum calcium and parathyroid hormone."( Allendorf, JD; Bubis, L; Chabot, JA; Epelboym, I; Herman, MC; Kuo, JH; Lee, JA; Lim, JY, 2017)
"Primary hyperparathyroidism is primarily due to a solitary parathyroid adenoma but multi-gland disease, parathyroid carcinoma, and ectopic parathyroid hormone production can occur."( Arnold, A, 2016)
"Juvenile primary hyperparathyroidism is uncommon and more symptomatic than the adult counterpart."( Borsari, S; Cacciatore, F; Cetani, F; Marcocci, C; Materazzi, G; Miccoli, M; Miccoli, P; Pardi, E; Saponaro, F, 2018)
"Primary hyperparathyroidism is a disease that occurs more frequently than generally thought and is often overlooked."( Nies, C, 2017)
"Primary hyperparathyroidism is caused by single gland disease in 85% of cases and by multiglandular disease in 15%."( Albarano, A; Carty, SE; Ghodadra, AG; Hiremath, TG; Joyce, JM; McCoy, KL; Muthukrishnan, A; Yip, L, 2018)
"Primary hyperparathyroidism is overlooked and underdiagnosed in a number of patients in the clinical setting."( Bayadsi, H; Enell, J; Hennings, J; Lundgren, E, 2018)
"Primary hyperparathyroidism is commonly caused by excess production of parathyroid hormone from sporadic parathyroid adenomas."( Fan, YB; Fu, WZ; He, JW; Sun, B; Wang, ZP; Wei, Z; Zhang, ZL, 2018)
"Patients with primary hyperparathyroidism are at risk for skeletal and renal end-organ damage."( Adams, AL; Assadipour, Y; Haigh, PI; Kuo, EJ; Yeh, MW; Zhou, H, 2019)
"Primary hyperparathyroidism is a relatively common condition affecting calcium homoeostasis, in which MPC can rarely occur."( Kamalanathan, S; Lakshmana Perumal, N; Sahoo, JP; Selvi, J, 2019)
"Primary hyperparathyroidism is mostly asymptomatic and does not affect conception or pregnancy."( Leere, JS; Vestergaard, P, 2019)
"Primary hyperparathyroidism is often associated with non-disease-specific symptoms."( Bränström, R; Koman, A; Nilsson, IL; Ohlsson, S; Pernow, Y, 2019)
"Primary hyperparathyroidism is associated with an increased cardiovascular mortality, but mechanisms underlying this association are unclear."( Bihain, F; Brunaud, L; Croise-Laurent, V; Demarquet, L; Koubaity, O; Mandry, D; Nguyen-Thi, PL; Nomine-Criqui, C, 2020)
"Background Primary hyperparathyroidism is the third most common endocrine disorder for which surgical procedure called parathyroidectomy is the most effective treatment."( Hocevar, M; Majcen, M, 2020)
"Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the localization of the adenoma to resect."( Aschenbach, R; Biermann, A; Freesmeyer, M; Kloos, C; Lupp, A; Mtuka-Pardon, G; Seifert, P; Werner, C; Wolf, G, 2020)
"Primary hyperparathyroidism is the most common cause of hypercalcemia."( Kamejima, S; Kobayashi, A; Nakashima, A; Ohkido, I; Uchiyama, T; Yamamoto, I; Yokoo, T, 2021)
"Normocalcaemic primary hyperparathyroidism is a condition that can present with intermittent hypercalcemia or may evolve into hypercalcemic primary hyperparathyroidism."( Dawood, NB; Leung, AM; Livhits, MJ; Shieh, A; Yan, KL; Yeh, MW, 2020)
"Primary hyperparathyroidism is characterised by autonomous production of parathyroid hormone resulting in hypercalcaemia."( Castle, C; Tietjens, J, 2021)
"Primary hyperparathyroidism is characterized by an autonomous hypersecretion of parathyroid hormone by one or more parathyroid glands."( Barale, M; Berton, AM; Bioletto, F; Deandreis, D; Ghigo, E; Parasiliti-Caprino, M; Prencipe, N; Procopio, M, 2021)
"Primary hyperparathyroidism is not so uncommon a disease."( Jain, A; Khandelwal, N; Silodia, A; Yadav, N; Yadav, SK, 2022)
"Primary hyperparathyroidism is a biochemical, not radiologic diagnosis."( Brumund, KT; Bykowski, J; Kimura, B; Koo, SJ; McCowen, KC; Nagelberg, J, 2021)
"Normocalcemic primary hyperparathyroidism is an entity on which several issues about its clinical management remains unclear."( Huguet-Moreno, I; Marazuela Azpiroz, M; Muñoz de Nova, JL; Sampedro-Nuñez, M, 2021)
"Primary hyperparathyroidism is caused by uncontrolled and immoderate secretion of parathyroid hormone."( Li, C; Zhang, J; Zhu, Y, 2021)
"Primary hyperparathyroidism is a common endocrine disorder."( Cusano, NE, 2021)
"Sporadic primary hyperparathyroidism is a common endocrinopathy, particularly afflicting postmenopausal women and both African American men and women."( Kim, SJ; Shoback, DM, 2021)
"The primary hyperparathyroidism is a frequent disease whom the surgery is the only curative treatment."( Agirre, L; Arana, A; de la Quintana, A; Larrea, J; Martínez, G; Servide, MJ, 2022)
"Primary hyperparathyroidism is now largely managed surgically via minimally invasive techniques."( Abraham, MN; Abraham, PJ; Chen, H; Lindeman, B, 2023)
"Primary hyperparathyroidism is associated with an increased cardiovascular mortality, and its underlying mechanisms remain unclear."( Al-Ahmed, F; Al-Jehani, A; Bihain, F; Brunaud, L; Demarquet, L; Guerci, B; Nguyen-Thi, PL; Nomine-Criqui, C; Ziegler, O, 2022)
"Primary hyperparathyroidism is the third most common endocrine disease."( Arias, A; Garzón, A; Guzmán, L; Olguín Joseau, S; Peretti, E; Ruggieri, M, 2022)
"Primary hyperparathyroidism is a safe procedure in terms of morbidity and long-term outcomes."( Arias, A; Garzón, A; Guzmán, L; Olguín Joseau, S; Peretti, E; Ruggieri, M, 2022)
"Three phenotypes of primary hyperparathyroidism are distinct clinical entities."( Armstrong, VL; Butterfield, R; Cronin, PA; Hangge, PT; Norain, A; Stucky, CH; Wasif, N, 2023)
"Primary hyperparathyroidism is a common endocrine disease and most cases are asymptomatic."( Bestepe, N; Cakir, B; Cuhaci, FN; Ersoy, R; Ogmen, BE; Ozdemir, D; Polat, B, 2022)
"Primary hyperparathyroidism is a common endocrine disease and most cases are asymptomatic."( Bestepe, N; Cakir, B; Cuhaci, FN; Ersoy, R; Ogmen, BE; Ozdemir, D; Polat, B, 2022)
"Normocalcemic primary hyperparathyroidism is a variant of primary hyperparathyroidism with consistently normal albumin-adjusted or free-ionized calcium levels."( Chertok Shacham, E; Ishay, A; Lazareva, T; Mahagna, L; Maman, N; Masalha, R; Sela, G, 2023)
"Normohormonal primary hyperparathyroidism is a term used to describe patients with a normal PTH and elevated calcium levels."( Nabata, KJ; Wiseman, JJ; Wiseman, SM, 2023)
"Primary hyperparathyroidism is a common endocrine disorder, with 80% of all cases usually caused by one single hyperfunctioning parathyroid adenoma."( Aloj, L; Bashari, WA; Buch, HN; Casey, RT; Challis, BG; Cheow, HK; Chung, TT; Das, T; Fish, B; Gillett, D; Gurnell, M; Harper, I; Huynh, KA; Inchiappa, D; Jani, P; Koulouri, O; MacFarlane, J; Masterson, L; Mendichovszky, IA; Moyle, P; Newman, C; Powlson, AS; Scoffings, D; Simpson, HL; Stokes, VJ, 2023)

Context

ExcerptReference
"Surgery for primary hyperparathyroidism has traditionally involved a bilateral neck exploration performed as an in-patient procedure."( Burke, M; Carr, ER; Contractor, K; Remedios, D, 2006)
"Patients with primary hyperparathyroidism have higher serum leptin levels than healthy subjects."( Chang, YC; Cheng, SP; Doherty, GM; Liu, CL, 2011)
"Primary hyperparathyroidism has been studied more extensively in adults than in adolescents."( Angelos, P; Devon, K; Grogan, RH; Kaplan, EL; Kaplan, SP; Liu, D; Pashtan, I, 2013)
"Primary hyperparathyroidism has typically been considered a disease that uncommonly affects cats, but this condition is more prevalent than previous diagnoses would suggest."( Chew, DJ; Gilor, C; Parker, VJ, 2015)
"Primary hyperparathyroidism has some metabolic consequences in the calcium metabolism."( Harbuwono, DS; Larasati, D; Pramono, LA; Soebardi, S; Yossy, Y, 2015)
"Although primary hyperparathyroidism has been associated with insulin resistance, potential optimal effects of parathyroidectomy (PTX) on glucose homeostasis remain controversial."( Antonopoulou, V; Gerou, S; Karras, SN; Katsiki, N; Kotsa, K; Koufakis, T; Papavramidis, T; Yavropoulou, M, 2020)

Treatment

ExcerptReference
"Drugs for treating primary hyperparathyroidism can be divided into two main groups: (i) antiresorptive drugs that inhibit the increased bone turnover, which can be divided into estrogen-like compounds (estrogen, oral contraceptives and selective estrogen receptor modulators [SERMs]), bisphosphonates and calcitonin; and (ii) drugs that interfere with parathyroid hormone (PTH) secretion (currently only cinacalcet is available)."( Vestergaard, P, 2006)
"Surgery is the only curative treatment for primary hyperparathyroidism."( Bäckdahl, M; Chandanos, E; Jacobsson, H; Kjellman, M; Lindqvist, V; Wallin, G, 2009)
"Surgery is the recommended treatment for primary hyperparathyroidism."( Mosekilde, L; Vestergaard, P, 2009)
"Guidelines for operative treatment of primary hyperparathyroidism include calcium levels >1 mg/dL above normal."( Boone, D; Lopez, J; Mitchell, J; Norman, J; Parrack, K; Politz, D, 2017)
"Surgery remains the most effective treatment for primary hyperparathyroidism (PHPT)."( Asadi, M; Jangjoo, A; Khaje, M; Mohebbi, M; Mousavi, Z; Sadeghi, R, 2017)
"Surgical treatment for primary hyperparathyroidism (PHPT) improves bone metabolism."( Abdel-Misih, R; Balagopal, PB; Lenhard, MJ; Maser, RE; Pohlig, RT, 2018)
"Parathyroidectomy is the only curative treatment for primary hyperparathyroidism (PHPT)."( Bishara, B; Ish-Shalom, S; Kluger, Y; Levit, B; Mekel, M; Segal, E, 2017)
"Parathyroidectomy is the only curative treatment for primary hyperparathyroidism (pHPT) and is associated with low morbidity."( Doffek, K; Dream, S; Evans, DB; Mazotas, I; O'Sullivan, K; Wang, TS; Yen, TWF, 2021)
"Curative treatment for primary hyperparathyroidism (PHPT) is parathyroidectomy (PTX) with removal of the hyperfunctioning gland(s)."( Arikan, M; Hargitai, L; Haug, A; Riss, P; Schefner, M; Scheuba, C; Traub-Weidinger, T, 2022)
"Patients successfully treated for primary hyperparathyroidism were analyzed."( Buerba, GA; Herrera, MF; León-Cabral, P; Pérez-Soto, RH; Sierra-Salazar, M; Velázquez-Fernández, D, 2023)
"Parathyroidectomy is the only curative treatment for primary hyperparathyroidism (PHPT)."( He, Y; Jin, S; Liao, Q; Liu, H; Luo, Y; Wang, O; Zhu, Q, 2023)

Research

Studies (1,463)

TimeframeStudies, This Condition (%)All Conditions %
pre-199035 (2.39)23.3326
1990's0 (0.00)12.5806
2000's307 (20.98)18.1394
2010's722 (49.35)28.8240
2020's399 (27.27)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
adenine0low10
choline0medium562
citric acid, anhydrous0low20
chlorine0low50
creatine0low30
glycine0medium21
hydrogen carbonate0low10
kynurenine0medium21
racemethionine0low20
quinolinic acid0medium11
uric acid0medium61
urea0medium11
alendronate0medium152
anastrozole0low10
cimetidine0low10
etidronate0low10
felodipine0low10
furosemide0low50
hydrochlorothiazide0low10
iodixanol0low10
iohexol0low10
iomeprol0low20
isoproterenol0low20
lorazepam0low10
mechlorethamine0low10
midazolam0low10
pamidronate0low40
potassium chloride0low20
procarbazine0low10
propofol0medium11
risperidone0low10
sodium iodide0low10
risedronic acid0low10
succinylcholine0low10
sulfaphenazole0low10
ticlopidine0low10
thymidine0low10
hydroxyproline0low10
thyroxine0low30
spironolactone0medium62
aldosterone0medium121
prednisone0low20
glutamine0low10
lysine0low10
tyrosine0low10
methylene blue0low30
methionine0low120
medroxyprogesterone acetate0low10
tryptophan0medium21
arginine0medium21
thiophenes0low20
homoarginine0low10
calcium gluconate0medium31
perfluorobutane0low20
limestone0medium43
lithium carbonate0low30
potassium citrate0medium11
durapatite0low10
amiloride0medium11
sulfur hexafluoride0low10
metanephrine0low10
technetium0low80
gadolinium0low10
magnesium sulfate0low10
phosphoric acid, trisodium salt0low10
tricalcium phosphate0low40
clodronic acid0low20
monoethylcholine0low10
technetium 99m0low20
bromocriptine0low10
cetylpyridinium chloride anhydrous0medium11
4-methoxyamphetamine0low10
calcium oxalate0low80
raloxifene hydrochloride0medium51
clopidogrel0low10
remifentanil0low10
ibandronic acid0medium31
testosterone undecanoate0low10
iopamidol0low20
triazoles0low10
fluorodeoxyglucose f180low110
sertraline0low10
zoledronic acid0medium51
6-amino-1-hydroxyhexane-1,1-diphosphonate0low10
fibrinogen0low20
2'-(2-hydroxyphenyl)-2'-thiazoline-4'-carboxylic acid0low10
calcium phosphate, dibasic, dihydrate0low20
vitamin b 60low10
n-nitrosothiazolidine-4-carboxylic acid0low10
omega-n-methylarginine0low10
proline0low10
cinacalcet0medium979
nps-5680low20
ropivacaine0low10
cortisone0low20
fluorocholine0medium442
n,n-dimethyl-n-(18f)fluoromethyl-2-hydroxyethylammonium0low150
glycogen0low10
eplerenone0medium53
retinol0low10
tenofovir0low10
sodium bicarbonate0low10
isomethyleugenol0low20
lithium0low50
alpha-chymotrypsin0low10
osteoprotegerin0low70
calcitriol0medium303
vitamin d 20low20
cholecalciferol0medium143
deamino arginine vasopressin0low10
lisinopril0low10
thallium-2010low10
phosphorus0medium564
25-hydroxyvitamin d 20low20
oxalates0low40
whewellite0low10
gadolinium dtpa0low20
lactulose0low10
losartan potassium0low20
technetium tc 99m exametazime0low10
indocyanine green0medium51
acid phosphatase0low10
carbon-11 methionine0low60
glucagon-like peptide 10low10
calpain0low10
technetium tc 99m sestamibi0medium38512
sodium pertechnetate tc 99m0medium51
quetiapine fumarate0low10
peptones0medium11
piperidines0low10
natriuretic peptide, brain0low30
ascorbic acid0low10
transforming growth factor beta0low10
rome0low20
cyclin d10low80
technetium tc 99m medronate0low50
technetium tc-99m tetrofosmin0low30
neopterin0low10
dacarbazine0low10
allopurinol0medium11
eye0low20
trypsinogen0low20
leptin0low30

Protein Targets (927)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A9009
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase4004
thioredoxin reductase170017
USP1 protein, partial140014
TDP1 protein250025
vitamin D3 receptor isoform VDRA9009
importin subunit beta-1 isoform 12002
flap endonuclease 18008
serine/threonine-protein kinase PLK12002
snurportin-12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)140014
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
geminin280028
DNA polymerase kappa isoform 16006
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0101
Transthyretin0114
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0112
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20112
Choline O-acetyltransferase0101
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G6006
Fatty acid-binding protein 50011
Fatty acid-binding protein 50011
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
5-hydroxytryptamine receptor 2C0314
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 1A0516
5-hydroxytryptamine receptor 1B0617
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0314
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0527
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Geranylgeranyl pyrophosphate synthase0809
Farnesyl pyrophosphate synthase012012
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE120012
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma170017
AR protein310031
nuclear receptor subfamily 1, group I, member 3160016
cytochrome P450 family 3 subfamily A polypeptide 4180018
glucocorticoid receptor [Homo sapiens]310031
estrogen-related nuclear receptor alpha240024
pregnane X nuclear receptor170017
estrogen nuclear receptor alpha340034
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a160016
nuclear factor erythroid 2-related factor 2 isoform 29009
heat shock protein beta-19009
tumor susceptibility gene 101 protein1001
lamin isoform A-delta10260026
Voltage-dependent calcium channel gamma-2 subunit110011
Bile salt export pump026026
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Glutamate receptor 2111012
Xanthine dehydrogenase/oxidase0303
TAR DNA-binding protein 436006
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 56006
Ataxin-28008
thyroid hormone receptor beta isoform a100010
Sex hormone-binding globulin0033
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 06310
Androgen receptor0708
Mineralocorticoid receptor0303
Solute carrier organic anion transporter family member 1A10001
Chain A, farnesyl pyrophosphate synthase0101
Acetylcholinesterase0202
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0606
Farnesyl pyrophosphate synthase 0303
interleukin 86006
thyroid stimulating hormone receptor120012
estrogen receptor 2 (ER beta)100010
progesterone receptor160016
IDH19009
euchromatic histone-lysine N-methyltransferase 2310031
Bloom syndrome protein isoform 1100010
transcriptional regulator ERG isoform 35005
thyroid hormone receptor beta isoform 2180018
ras-related protein Rab-9A2002
nuclear factor erythroid 2-related factor 2 isoform 1200020
survival motor neuron protein isoform d9009
ATP-binding cassette sub-family C member 3016016
Multidrug resistance-associated protein 4016016
Polyphenol oxidase 20203
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p53170017
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0112
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
Canalicular multispecific organic anion transporter 1015015
Shiga toxin subunit A0101
Histamine H3 receptor0101
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, 2-oxoglutarate Oxygenase7007
acetylcholinesterase100010
aldehyde dehydrogenase 1 family, member A1140014
regulator of G-protein signaling 47007
glucocerebrosidase3003
arylsulfatase A8008
alpha-galactosidase3003
cytochrome P450 2D6 isoform 13003
lysosomal alpha-glucosidase preproprotein2002
cytochrome P450 2C19 precursor8008
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
huntingtin isoform 24004
Membrane primary amine oxidase 0101
Solute carrier family 22 member 1 0405
Prothrombin0112
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0202
Tissue-type plasminogen activator0202
Cationic trypsin0101
Coagulation factor XI0101
Plasma kallikrein0103
Vitamin K-dependent protein C0101
Urokinase-type plasminogen activator0202
Trypsin-10101
Trypsin-20101
Sodium/hydrogen exchanger 10101
Amine oxidase [flavin-containing] A0202
Sodium/hydrogen exchanger 10202
Sodium/hydrogen exchanger 30202
Trypsin-30101
Amiloride-sensitive sodium channel subunit alpha0101
5-hydroxytryptamine receptor 70101
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10101
Potassium voltage-gated channel subfamily H member 20505
Sodium channel protein type 5 subunit alpha0202
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 10405
Solute carrier family 22 member 20405
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
G130013
Interferon beta160016
HLA class I histocompatibility antigen, B alpha chain 130013
Aromatase0202
Cytochrome P450 2C9 010011
Amine oxidase [flavin-containing] A 0101
UDP-glucuronosyltransferase 1A40303
Spike glycoprotein130013
Inositol hexakisphosphate kinase 1130013
cytochrome P450 2C9, partial130013
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase110011
NFKB1 protein, partial2002
GLS protein8008
chromobox protein homolog 1150015
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)6006
Cytochrome P450 3A408010
Nitric oxide synthase, endothelial0103
Nitric oxide synthase, brain0203
Nitric oxide synthase, brain 0203
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0215
Cationic amino acid transporter 30202
ATP-dependent phosphofructokinase9009
Chain A, Hyaluronidase, phage associated0101
GLI family zinc finger 3180018
thioredoxin glutathione reductase6006
retinoic acid nuclear receptor alpha variant 1200020
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Pancreatic alpha-amylase0202
Albumin0102
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0819
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Genome polyprotein 0112
dopamine D1 receptor2002
ATAD5 protein, partial9009
Fumarate hydratase7007
polyprotein7007
peroxisome proliferator activated receptor gamma140014
D(1A) dopamine receptor5005
serine/threonine-protein kinase mTOR isoform 14004
5-hydroxytryptamine receptor 40808
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10607
Beta-1 adrenergic receptor0415
5-hydroxytryptamine receptor 1A0224
Alpha-2A adrenergic receptor0808
D(2) dopamine receptor0516
Alpha-2C adrenergic receptor0808
D0303
D(3) dopamine receptor0303
Alpha-2B adrenergic receptor0404
ATP-dependent translocase ABCB10303
D(1A) dopamine receptor0505
Alpha-2C adrenergic receptor0404
Alpha-2A adrenergic receptor0404
Alpha-1D adrenergic receptor0415
D(1B) dopamine receptor0202
5-hydroxytryptamine receptor 2A0617
5-hydroxytryptamine receptor 2C0819
D(4) dopamine receptor0202
D(3) dopamine receptor0505
Alpha-synuclein3205
5-hydroxytryptamine receptor 2B0808
5-hydroxytryptamine receptor 60303
D(2) dopamine receptor0415
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase4004
Chain A, Ferritin light chain100010
Vitamin D3 receptor0011
PPM1D protein5005
Microtubule-associated protein tau110011
mitogen-activated protein kinase 14004
nuclear receptor ROR-gamma isoform 19009
peripheral myelin protein 22140014
Vitamin D-binding protein0011
Cytochrome P450 1A20001
Androgen receptor07411
Cytochrome P450 2D60606
Vitamin D3 receptor0239
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0033
Cytochrome P450 2C190707
Kappa-type opioid receptor0011
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0202
Vitamin D3 receptor A0022
Histone H2A.x6006
hypoxia-inducible factor 1 alpha subunit4004
SMAD family member 26006
SMAD family member 36006
caspase 7, apoptosis-related cysteine protease5005
retinoid X nuclear receptor alpha100010
farnesoid X nuclear receptor120012
67.9K protein4004
peroxisome proliferator-activated receptor delta110011
caspase-35005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
activating transcription factor 68008
thyrotropin-releasing hormone receptor2002
v-jun sarcoma virus 17 oncogene homolog (avian)110011
Caspase-20011
Inositol monophosphatase 13003
Carbonic anhydrase 1011015
Carbonic anhydrase 2012016
Carbonic anhydrase 407010
Carbonic anhydrase0507
Carbonic anhydrase 150204
Chain A, Cruzipain4004
Luciferase5005
15-lipoxygenase, partial6006
cytochrome P450 3A4 isoform 1100010
Gamma-aminobutyric acid receptor subunit pi104216
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Gamma-aminobutyric acid receptor subunit beta-1104216
Gamma-aminobutyric acid receptor subunit delta104216
Gamma-aminobutyric acid receptor subunit gamma-2104317
Gamma-aminobutyric acid receptor subunit alpha-5104216
Gamma-aminobutyric acid receptor subunit alpha-3104216
Glycine receptor subunit alpha-10044
Gamma-aminobutyric acid receptor subunit gamma-1104216
Gamma-aminobutyric acid receptor subunit alpha-2104216
Gamma-aminobutyric acid receptor subunit alpha-4104216
Gamma-aminobutyric acid receptor subunit gamma-3104216
Gamma-aminobutyric acid receptor subunit alpha-6104216
Nuclear receptor ROR-gamma4004
10 kDa heat shock protein, mitochondrial0202
Gamma-aminobutyric acid receptor subunit alpha-1104317
Gamma-aminobutyric acid receptor subunit beta-3104216
Gamma-aminobutyric acid receptor subunit beta-2104317
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
GABA theta subunit104216
Gamma-aminobutyric acid receptor subunit epsilon104216
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20305
Solute carrier family 22 member 20202
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
cytochrome P450 2D6100010
M-phase phosphoprotein 85005
Solute carrier family 22 member 60404
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Potassium-transporting ATPase alpha chain 10101
Histamine H2 receptor0606
Histamine H1 receptor0112
Histamine H2 receptor3227
Potassium-transporting ATPase subunit beta0101
Cytochrome P450 2J20606
Aldehyde oxidase0101
Solute carrier family 22 member 60103
Multidrug and toxin extrusion protein 20202
Solute carrier family 22 member 80305
Multidrug and toxin extrusion protein 10505
Histamine H4 receptor0101
Solute carrier family 22 member 110101
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
Smad39009
PINK12002
EWS/FLI fusion protein110011
Parkin3003
Extracellular calcium-sensing receptor0022
Angiotensin-converting enzyme 2 0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
72 kDa type IV collagenase0202
Stromelysin-10202
Matrix metalloproteinase-90303
Macrophage metalloelastase0101
nonstructural protein 15005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
Cytochrome P450 2C80303
Cytochrome P450 2B60303
Liver carboxylesterase 10001
Rap guanine nucleotide exchange factor 42002
P2Y purinoceptor 120101
endonuclease IV3003
pregnane X receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
peripheral myelin protein 22 isoform 17007
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor010414
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10505
thyroid stimulating hormone receptor8008
Isocitrate lyase0101
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
GALC protein1001
Estrogen receptor0538
Progesterone receptor0639
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Estrogen receptor beta0437
apical membrane antigen 1, AMA13003
aryl hydrocarbon receptor7007
histone acetyltransferase KAT2A isoform 13003
glp-1 receptor, partial9009
Cathepsin B0101
potassium voltage-gated channel subfamily H member 2 isoform d7007
procathepsin L isoform 1 preproprotein0101
fructose-bisphosphate aldolase0101
neuropeptide S receptor isoform A8008
Nuclear receptor subfamily 1 group I member 20022
Adenosine receptor A30202
Alpha-1B adrenergic receptor0606
Alpha-1A adrenergic receptor0606
Aurora kinase B0011
Bile acid receptor0202
Nuclear receptor subfamily 1 group I member 20011
Carbonic anhydrase 120306
Bile salt export pump0303
Albumin0202
Carbonic anhydrase 30204
Glucose-6-phosphate 1-dehydrogenase0202
Carbonic anhydrase 60205
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0508
Carbonic anhydrase 70205
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0101
Carbonic anhydrase 90609
Carbonic anhydrase 130204
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Carbonic anhydrase 140306
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Carbonic anhydrase 5B, mitochondrial0407
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0022
bromodomain adjacent to zinc finger domain 2B4004
histone-lysine N-methyltransferase 2A isoform 2 precursor6006
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10224
Gamma-aminobutyric acid receptor subunit gamma-20325
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30325
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50224
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20224
Gamma-aminobutyric acid receptor subunit beta-20224
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40224
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0202
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Histone deacetylase 10101
Gamma-aminobutyric acid receptor subunit alpha-60224
Sterol O-acyltransferase 10011
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Gamma-aminobutyric acid receptor subunit gamma-30202
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Gamma-aminobutyric acid receptor subunit theta0202
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Chain A, Glutamine Binding Protein0011
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10202
Neutral amino acid transporter B(0)0303
Carbonic anhydrase-like protein, putative0003
Amino acid transporter0303
Glutamate receptor ionotropic, NMDA 1 0428
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0327
Glutamate receptor ionotropic, NMDA 2B0327
Glutamate receptor ionotropic, NMDA 2C0327
Large neutral amino acids transporter small subunit 10404
Glutamate receptor ionotropic, NMDA 2D0327
Glutamate receptor ionotropic, NMDA 3B0327
Serine racemase0101
Olfactory receptor 51E20022
Glutamate receptor ionotropic, NMDA 3A0327
Sodium- and chloride-dependent glycine transporter 20101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Carbonic anhydrase 0303
Carbonic anhydrase 0101
cytochrome P450 2C9 precursor2002
Delta-type opioid receptor0101
Delta-type opioid receptor0101
Mu-type opioid receptor0404
Mu-type opioid receptor0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
nuclear receptor subfamily 1, group I, member 22002
NPYLR7B0011
Beta-1 adrenergic receptor 0012
beta-2 adrenergic receptor1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Beta-2 adrenergic receptor0225
Beta-2 adrenergic receptor0213
Polyunsaturated fatty acid lipoxygenase ALOX150202
Beta-3 adrenergic receptor0112
Beta-1 adrenergic receptor0315
Beta-2 adrenergic receptor0011
D(4) dopamine receptor0202
Alpha-1D adrenergic receptor0404
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0112
D(1A) dopamine receptor2002
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310022
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0022
Taste receptor type 2 member 160011
Taste receptor type 2 member 140023
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Angiotensin-converting enzyme 0303
Angiotensin-converting enzyme0606
Type-2 angiotensin II receptor0202
Angiotensin-converting enzyme0101
Fatty acid-binding protein, liver0101
Translocator protein0101
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0202
Type-1 angiotensin II receptor0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0304
Androgen receptor0011
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Aldo-keto reductase family 1 member C10101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain E, Fibrin beta chain0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial1001
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
histone deacetylase 9 isoform 31001
pyruvate kinase PKM isoform a1001
DNA polymerase beta2002
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
Vpr2002
muscleblind-like protein 1 isoform 12002
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Amyloid-beta precursor protein0202
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Sodium-dependent noradrenaline transporter 0426
Cruzipain0101
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Translocator protein0101
UDP-glucuronosyltransferase 2B70202
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A1 0303
UDP-glucuronosyltransferase 2B10 0202
Atrial natriuretic peptide receptor 10101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10102
Neutrophil elastase0101
Proteinase-activated receptor 10101
Nitric oxide synthase, endothelial0202
Collagenase 30101
Nitric oxide synthase, brain0101
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Glutamate 5-kinase0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Aldo-keto reductase family 1 member B10404
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Prostaglandin G/H synthase 10101
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A80001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Lysine-specific demethylase 4E0101
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Advanced glycosylation end product-specific receptor0011
Beta-lactamase 0101
Advanced glycosylation end product-specific receptor0011
Prolyl 4-hydroxylase, beta polypeptide0001
Caspase-71001
cellular tumor antigen p53 isoform a1001
caspase-31001
nuclear factor NF-kappa-B p105 subunit isoform 11001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-31001
Estrogen receptor0101
Integrin alpha-IIb1001
Gastric inhibitory polypeptide receptor0101
Estrogen receptor beta0101
Sigma non-opioid intracellular receptor 10112
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 172002
Butyrophilin subfamily 3 member A10023
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Albumin0011
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M50303
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30202
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
5-hydroxytryptamine receptor 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Nuclear receptor subfamily 3 group C member 3 0404
Transporter0202
Histamine H3 receptor0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Potassium channel subfamily K member 30101
NPC intracellular cholesterol transporter 1 precursor1001
atrial natriuretic peptide receptor 2 precursor1001
Rap guanine nucleotide exchange factor 34004
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Melanocortin receptor 50202
Sodium-dependent dopamine transporter 0213
Envelope glycoprotein0011
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10101
Carbonic anhydrase 0202
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Acetylcholinesterase0101
Thrombopoietin1001
Cytochrome P450 2C180101
Lanosterol 14-alpha demethylase0101
Adenylate kinase isoenzyme 10001
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Adenylate kinase 2, mitochondrial0001
Capsid protein 0011
Reverse transcriptase/RNaseH 0114
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidylate synthase0001
Thymidine phosphorylase0001
Polyunsaturated fatty acid 5-lipoxygenase0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Solute carrier organic anion transporter family member 1A40103
Solute carrier organic anion transporter family member 1A50002
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10002
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1B30001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Myeloperoxidase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0002
SLC16A10 protein0002
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0002
Tryprostatin B synthase0001
Carbonic anhydrase0002
Carbonic anhydrase0002
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Adenosine receptor A10001
Adenosine receptor A2a0001
Tubulin--tyrosine ligase0101
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
eyes absent homolog 2 isoform a1001
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]