tocopherol

A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.

ChEBI ID: 27013

Members (4)

Member	Definition	Role
beta-tocopherol	A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts.	beta-tocopherol
delta-tocopherol	A tocopherol in which the chroman-6-ol core is substituted by a methyl group at position 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.	delta-tocopherol
gamma-tocopherol	A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.	gamma-tocopherol
tocopheroxy radical		2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol

Research

Studies (653)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	16 (2.45)	18.7374
1990's	9 (1.38)	18.2507
2000's	290 (44.41)	29.6817
2010's	277 (42.42)	24.3611
2020's	61 (9.34)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	77 (10.56%)	5.53%
Reviews	38 (5.21%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	614 (84.22%)	84.16%