Page last updated: 2024-08-05 11:04:59
tocopherol
A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.
ChEBI ID: 27013
Members (4)
| Member | Definition | Role |
|---|---|---|
| beta-tocopherol | A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. | beta-tocopherol |
| delta-tocopherol | A tocopherol in which the chroman-6-ol core is substituted by a methyl group at position 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils. | delta-tocopherol |
| gamma-tocopherol | A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils. | gamma-tocopherol |
| tocopheroxy radical | 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol |
Research
Studies (653)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 16 (2.45) | 18.7374 |
| 1990's | 9 (1.38) | 18.2507 |
| 2000's | 290 (44.41) | 29.6817 |
| 2010's | 277 (42.42) | 24.3611 |
| 2020's | 61 (9.34) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 77 (10.56%) | 5.53% |
| Reviews | 38 (5.21%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 614 (84.22%) | 84.16% |