CACH Syndrome

Any of various diseases affecting the white matter of the central nervous system.

Synonym
Leukoencephalopathies
Leukoencephalopathy with Vanishing White Matter
CACH VWM Syndrome
White Matter Diseases
Vanishing White Matter Disease
Vanishing White Matter Leukodystrophy
Cree Leukoencephalopathy
Childhood Ataxia with Central Nervous System Hypomyelinization
Childhood Ataxia with Central Nervous System Hypomyelination
Leukoencephalopathy
Childhood Ataxia with Diffuse Central Nervous System Hypomyelination
CACH Syndrome
Myelinosis Centralis Diffusa

Excerpt	Reference
"Chronic leukoencephalopathy is a well-known side effect of MTX, especially in conjunction with intrathecal administration."	( Agarwal, A; Ouyang, T; Thamburaj, K; Vijay, K, 2011)
"Leukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter."	( Tormoehlen, LM, 2011)
"Leukoencephalopathy is a well-described adverse effect of MTX therapy and is associated with a wide range of neurological sequelae."	( Abramowsky, CR; Cooper, TM; Summers, RJ, 2014)
"Leukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter."	( Tormoehlen, LM, 2013)
"Cocaine-induced leukoencephalopathy is a rare neurological complication."	( González-Duarte, A; Williams, R, 2013)
"Toxic leukoencephalopathy is a possible but rare complication of chronic cocaine abuse."	( Del Mar Ramirez Fernandez, M; Di Fazio, V; Duprez, T; Hantson, P; Samyn, N; van Pesch, V, 2015)
"Leukoencephalopathy is observed in some children undergoing chemotherapy for acute lymphoblastic leukaemia, although its effects on long-term outcomes is unknown."	( Bhojwani, D; Brinkman, TM; Cheung, YT; Glass, JO; Hudson, MM; Hwang, SN; Krull, KR; Liu, W; Pui, CH; Reddick, WE; Robison, LL; Sabin, ND; Srivastava, D, 2016)
"Leukoencephalopathies are a group of white matter disorders related to abnormal formation, maintenance, and turnover of myelin in the central nervous system."	( Anikster, Y; Baze, WB; Bitterman-Deutsch, O; Chasnyk, N; Chopra, AK; Falik Zaccai, TC; Fitts, EC; Gahl, WA; Geiger, D; Gross, B; Kalfon, L; Keren, Z; Kirtley, ML; Kleta, R; Kornitzer, D; Mullikin, JC; Peterson, JW; Pinchuk, IV; Samra, N; Samson, AO; Savitzki, D; Shoval, Y; Straussberg, R; Teer, JK; Vilboux, T; Wakamiya, M; Zivony-Elboum, Y, 2017)
"Toxic leukoencephalopathy is a rare but critical neurological disorder in heroin abusers."	( Chang, BL; Chang, CW; Chang, YC; Cheng, MY; Chiang, HI; Chin, SC; Hsieh, HY; Hsu, JL; Li, HT; Lim, SN; Ro, LS; Tsai, MH; Tseng, WJ; Wu, T, 2019)
": Toxic leukoencephalopathy is a rare illness that causes diffuse white matter destruction, and as a result may mimic psychiatric disorders."	( Khan, M; Shmuts, R; Weitzer, D, 2020)
"Oxycodone-induced leukoencephalopathy is a rare diagnosis that should be considered in unconscious patients with appropriate history."	( Hampton, T; Jones, E; Kulendran, A; Mallu, H; Patel, M; Umasankar, U, 2020)
"Leukoencephalopathy is one of levamisole`s most prominent neurological side effects."	( Hız, S; Okur, D; Paketçi, C; Yiş, U, 2021)
"Leukoencephalopathy is identified during the administration of anticancer drugs."	( Ichikawa, M; Kawamata, Y; Maehara, R; Mitani, K; Shimoda, K; Yasui-Furukori, N, 2021)
"Toxic leukoencephalopathies are white matter disorders that result from either exogenous or endogenous sources."	( Martin, D; Opoku, A; Shah, NR; Tavana, S, 2022)

Excerpt	Reference
"Toxic leukoencephalopathy has been associated with illicit heroin vapor inhalation."	( Adelmann, M; Blasel, S; Hattingen, E; Nichtweiß, M; Weidauer, S; Zanella, F, 2010)
"Toxic leukoencephalopathy has been more thoroughly investigated during the last decade because of the advance of magnetic resonance imaging (MRI) techniques."	( Beitinjaneh, A; Cao, Q; McKinney, AM; Weisdorf, DJ, 2011)
"Leukoencephalopathies have been reported after heroin inhalation or ingestion, and buprenorphine injection, but the physiopathology remains unclear."	( Battaglia, F; Bellot, B; Chaumoitre, K; Lagier, P; Michel, F; Thomachot, L, 2011)

Excerpt	Reference
"Tacrolimus-related posterior reversible leukoencephalopathy (PRLE) is a rare complication which should be recognized by clinicians who regularly use immunosuppressive therapy."	( Baillon, JJ; Ben Cheikh, A; Ber, CE; Christin, F; Courand, PY; Rimmelé, T, 2010)
"Acute chemotherapy-related leukoencephalopathy can present similar to acute stroke with symptoms including aphasia, dysarthria, and hemiplegia."	( El-Hakam, LM; Illner, A; Ramocki, MB; Riviello, JJ, 2010)
"Chronic leukoencephalopathy is a well-known side effect of MTX, especially in conjunction with intrathecal administration."	( Agarwal, A; Ouyang, T; Thamburaj, K; Vijay, K, 2011)
"Early diagnosis and treatment of leukoencephalopathy syndrome should contribute to complete remission."	( Fujiwara, T; Matsuda, H; Sadamori, H; Sato, D; Shinoura, S; Umeda, Y; Utsumi, M; Yagi, T; Yoshida, R, 2011)
"Multifocal leukoencephalopathy developed in a 26-year-old man after levamisole treatment for verrucae."	( Cheng, YC; Po, HL, 2011)
"MTX-induced leukoencephalopathy can occur even with low-dose administration."	( Aguilar-Amat, MJ; Arpa, J; Borobia, AM; Cruz, A; González-Suárez, I; Trigueros, M, 2014)
"The patient was diagnosed with acute leukoencephalopathy, and the capecitabine treatment was discontinued."	( Ban, T; Ikegaya, Y; Isogai, N; Kawachi, J; Miyake, K; Ogino, H; Shimoyama, R; Watanabe, K, 2014)
"Acute leukoencephalopathy during chemotherapy treatment, without cranial radiation, for childhood acute lymphoblastic leukaemia predicted higher risk for long-term neurobehavioural problems and reduced white matter integrity in frontal brain regions."	( Bhojwani, D; Brinkman, TM; Cheung, YT; Glass, JO; Hudson, MM; Hwang, SN; Krull, KR; Liu, W; Pui, CH; Reddick, WE; Robison, LL; Sabin, ND; Srivastava, D, 2016)
"One patient developed leukoencephalopathy and parkinsonism within one year of treatment, one developed it seven years after treatment completion, and one developed dementia, parkinsonism and cerebral infracts 40 years after whole brain radiation."	( Itin, I; Jimenez-Shahed, J; Mehanna, R, 2016)
"Levamisole-induced leukoencephalopathy should be considered in the differential diagnosis of demyelinating diseases, the neurotoxic effects of the drug should be well understood, and treatment should be initiated as soon as possible."	( Hız, S; Okur, D; Paketçi, C; Yiş, U, 2021)
"Our cases showed that toxic leukoencephalopathy can also be caused by chemotherapy drugs other than methotrexate."	( Kang, J; Kim, H; Kim, SI; Lim, KY; Park, JW; Park, SH; Shin, DY; Won, JK, 2022)
"Acute toxic leukoencephalopathy (ATL) is a rare complication of cancer treatment, with symptoms varying from mild cognitive impairment to coma."	( Karaçin, C; Öztaş, A; Sertesen, E; Yoloğlu, Z, 2023)
"Toxic leukoencephalopathy (TLE) is a rare pathology caused by various substances including opioids (notably heroin), immunosuppressants, chemotherapy agents, cocaine, alcohol and carbon monoxide."	( Mahmood, M; Rossi, NP; Sathyanarayanan, G; Shakespeare, D, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	5 (1.04)	23.3326
1990's	0 (0.00)	12.5806
2000's	5 (1.04)	18.1394
2010's	381 (79.38)	28.8240
2020's	89 (18.54)	9.53

Drug	Relationship Strength	Studies	Trials
ethylene dichloride	low	1	0
alpha-hydroxyglutarate	low	1	0
2,5-dichlorophenol	low	1	0
ammonium hydroxide	low	1	0
carbon monoxide	low	3	0
carnitine	low	1	0
choline	low	6	0
chlorine	low	2	0
3-hydroxybutyric acid	low	1	0
methylmalonic acid	low	1	0
creatine	low	6	0
lactic acid	low	36	0
glycine	low	4	0
glycerol	low	1	0
methanol	low	1	0
inositol	low	1	0
melatonin	low	1	0
niacinamide	low	1	0
nitrous oxide	low	1	0
pyridoxine	low	1	0
succinic acid	low	2	0
toluene	low	7	0
uric acid	low	1	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	1	0
ibotenic acid	low	1	0
n-methyl-3,4-methylenedioxyamphetamine	low	1	0
phenytoin	low	3	0
7-chlorokynurenic acid	low	1	0
acetaminophen	low	1	0
adrenic acid	low	1	0
alprazolam	low	2	0
acetovanillone	low	1	0
aspirin	low	2	0
baclofen	low	1	0
busulfan	low	1	0
candesartan	low	2	0
celecoxib	low	1	0
cilostazol	medium	3	1
citalopram	medium	1	1
clofazimine	low	1	0
clonazepam	low	1	0
clonidine	low	1	0
deferoxamine	low	1	0
diazepam	low	1	0
valproic acid	low	2	0
fentanyl	low	5	0
fluorouracil	low	23	0
gentamicin	low	1	0
glyphosate	low	1	0
kynurenic acid	low	1	0
lorazepam	low	1	0
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1	0
edaravone	low	1	0
methadone	medium	6	1
methylphenidate	low	1	0
metoclopramide	low	1	0
metronidazole	low	3	0
mianserin	low	1	0
midazolam	low	2	0
mirtazapine	low	1	0
apnea	low	2	0
nimesulide	low	1	0
nitroglycerin	low	1	0
nortriptyline	low	1	0
4-dichlorobenzene	low	3	0
pentoxifylline	low	2	0
phenobarbital	low	1	0
piracetam	low	1	0
pyrimethamine	low	1	0
risperidone	low	1	0
fluoroacetic acid	low	1	0
tegafur	low	1	0
temozolomide	low	3	0
thalidomide	low	1	0
trihexyphenidyl	low	2	0
tyrphostin a9	low	1	0
zolpidem	low	1	0
prednisolone	low	3	0
thyroxine	low	2	0
penicillamine	low	1	0
prednisone	low	3	0
cantharidin	low	1	0
alanine	low	2	0
aspartic acid	low	12	0
lysine	low	2	0
cyanides	low	1	0
tetrabenazine	low	1	0
2,3,4,6-tetrachlorophenol	low	1	0
bromodeoxyuridine	low	1	0
levodopa	low	2	0
tyrosine	low	1	0
adenosine monophosphate	low	1	0
leucine	low	1	0
methionine	low	1	0
cytarabine	medium	4	1
ornithine	low	1	0
histidine	low	1	0
valine	low	2	0
arginine	low	1	0
propane	low	1	0
methylprednisolone	low	9	0
xylitol	low	1	0
1-naphthol	low	1	0
quinoxalines	low	3	0
1,2,3-trichloropropane	low	1	0
nitrobenzene	low	1	0
acrolein	low	1	0
sarin	low	1	0
2-naphthol	low	1	0
quinazolines	medium	2	1
thiazoles	low	1	0
cuprizone	low	3	0
fusarium	low	1	0
copper gluconate	low	1	0
methamphetamine	low	2	0
ethylnitrosourea	low	1	0
deoxycytidine	low	4	0
d-alpha tocopherol	low	2	0
s,n,n'-tripropylthiocarbamate	low	1	0
pimozide	low	1	0
sulfur hexafluoride	low	1	0
vidarabine	low	5	0
technetium	low	2	0
gadolinium	low	2	0
gold	low	2	0
magnesium sulfate	low	1	0
technetium 99m	low	1	0
phytanic acid	low	1	0
levamisole	low	12	0
daunorubicin	low	1	0
glutamic acid	low	3	0
amoxicillin	low	1	0
etoposide	low	1	0
diltiazem	low	1	0
captopril	low	1	0
clopidogrel	low	1	0
capecitabine	low	16	0
cathinone	low	2	0
cyclohexyl methylphosphonofluoridate	low	1	0
n-acetylaspartic acid	low	11	0
telmisartan	medium	1	1
triazoles	low	1	0
fluorodeoxyglucose f18	low	6	0
tianeptine	low	1	0
dipropylacetamide	low	1	0
bendamustine hydrochloride	low	1	0
fibrinogen	low	4	0
homocysteine	low	8	0
arabitol	low	1	0
cobalt	low	2	0
fotemustine	low	1	0
vitamin b 6	medium	3	1
fingolimod hydrochloride	low	1	0
imatinib mesylate	low	1	0
gefitinib	low	1	0
n(6)-carboxymethyllysine	low	1	0
pristanic acid	low	1	0
methotrexate	medium	43	2
ezetimibe	low	1	0
moxifloxacin	low	1	0
amotosalen	low	1	0
erlotinib hydrochloride	low	1	0
isospaglumic acid	low	1	0
cortisone	low	1	0
3-nitrotyrosine	low	1	0
glycogen	low	1	0
nicotinamide-beta-riboside	low	1	0
inositol 3-phosphate	low	1	0
arachidonic acid	low	1	0
tacrolimus	medium	10	1
cocaine	low	6	0
eicosapentaenoic acid	low	2	0
thapsigargin	low	1	0
mycophenolic acid	medium	1	1
methylproamine	low	1	0
iridoids	low	1	0
riboflavin	low	2	0
isomethyleugenol	low	1	0
stilbenes	low	1	0
buprenorphine	low	1	0
fludarabine	low	5	0
mercaptopurine	medium	2	1
capsaicin	low	1	0
fumonisin b1	low	1	0
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole	low	1	0
maraviroc	low	1	0
pica	low	1	0
cobaltous chloride	low	2	0
dasatinib	medium	1	1
zd 6474	medium	1	1
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	low	3	0
myelin basic protein	low	30	0
bilirubin	low	1	0
dinoprostone	low	2	0
8,11,14-eicosatrienoic acid	low	1	0
amphotericin b	low	1	0
oleuropein	low	1	0
coenzyme q10	low	1	0
14,15-dihydroxyeicosatrienoic acid	low	1	0
levetiracetam	low	3	0
oxycodone	low	5	0
morphine	low	4	0
lysophosphatidylcholines	low	2	0
tin	low	1	0
cysteine	low	2	0
heroin	low	19	0
cefepime	low	1	0
pregabalin	low	1	0
guanabenz	low	1	0
cefotaxime	low	1	0
selenium	low	1	0
i(3)so3-galactosylceramide	low	1	0
gadolinium dtpa	low	1	0
phosphocreatine	low	1	0
mocetinostat	low	1	0
perampanel	low	1	0
tocotrienols	medium	1	1
g(m1) ganglioside	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
alpha-synuclein	low	3	0
pirarubicin	low	1	0
losartan potassium	low	1	0
nad	low	2	0
angiotensinogen	low	1	0
endothelin-1	low	3	0
ubiquinone	low	1	0
intrinsic factor	low	1	0
quetiapine fumarate	low	1	0
plx4032	low	1	0
piperidines	medium	1	1
galactocerebroside	low	1	0
interleukin-8	low	2	0
hydroxocobalamin	low	2	0
eliglustat tartrate	medium	1	1
natriuretic peptide, brain	low	3	0
ascorbic acid	low	2	0
minocycline	low	4	0
bromadiolone	low	1	0
kaolinite	low	1	0
transforming growth factor beta	low	3	0
cobamamide	low	1	0
vitamin b 12	medium	9	1
cyclosporine	low	4	0
myelin oligodendrocyte glycoprotein (35-55)	low	1	0
exudates	medium	1	1
acyclovir	low	1	0
levoleucovorin	low	4	0
guanosine diphosphate	low	1	0
folic acid	medium	5	1
dacarbazine	low	2	0
5,10-methylenetetrahydrofolic acid	low	1	0
allopurinol	low	1	0
eye	low	1	0
technetium tc 99m bicisate	low	1	0
cog1410	low	1	0

Protein Targets (1,868)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Luciferase	17	0	0	17
RAR-related orphan receptor gamma	40	0	0	40
GLI family zinc finger 3	43	0	0	43
AR protein	69	0	0	69
estrogen receptor 2 (ER beta)	28	0	0	28
nuclear receptor subfamily 1, group I, member 3	36	0	0	36
progesterone receptor	32	0	0	32
retinoic acid nuclear receptor alpha variant 1	46	0	0	46
estrogen-related nuclear receptor alpha	61	0	0	61
farnesoid X nuclear receptor	27	0	0	27
pregnane X nuclear receptor	43	0	0	43
estrogen nuclear receptor alpha	82	0	0	82
peroxisome proliferator activated receptor gamma	31	0	0	31
aryl hydrocarbon receptor	21	0	0	21
Histone H2A.x	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 1	45	0	0	45
Prostaglandin G/H synthase 1	0	4	0	5
Prostaglandin G/H synthase 2	0	3	0	3
DNA repair and recombination protein RadA	0	0	2	2
Voltage-dependent calcium channel gamma-2 subunit	32	0	0	32
Cytochrome P450 1A2	0	11	0	12
Cytochrome P450 2A6	0	6	0	6
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Glutamate receptor 2	32	10	2	48
Cytochrome P450 2A5	0	4	0	4
UDP-glucuronosyltransferase 1A1	0	3	0	8
MAP kinase-activated protein kinase 2	0	2	4	6
peroxisome proliferator-activated receptor delta	26	0	0	26
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	25	0	0	25
Chain B, HADH2 protein	25	0	0	25
Chain A, 2-oxoglutarate Oxygenase	23	0	0	23
Chain A, Cruzipain	7	0	0	7
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	34	0	0	34
15-lipoxygenase, partial	11	0	0	11
ATAD5 protein, partial	18	0	0	18
NFKB1 protein, partial	7	0	0	7
TDP1 protein	64	0	0	64
Thrombopoietin	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	44	0	0	44
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
thyroid stimulating hormone receptor	31	0	0	31
regulator of G-protein signaling 4	18	0	0	18
EWS/FLI fusion protein	37	0	0	37
67.9K protein	20	0	0	20
Parkin	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	55	0	0	55
cytochrome P450 2D6 isoform 1	10	0	0	10
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C19 precursor	10	0	0	10
cytochrome P450 2C9 precursor	8	0	0	8
chromobox protein homolog 1	30	0	0	30
flap endonuclease 1	15	0	0	15
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
survival motor neuron protein isoform d	22	0	0	22
cytochrome P450 3A4 isoform 1	23	0	0	23
M-phase phosphoprotein 8	11	0	0	11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	3	3	7
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	4	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	3	4
Gamma-aminobutyric acid receptor subunit pi	23	9	1	33
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Bromodomain-containing protein 4	0	1	1	2
5-hydroxytryptamine receptor 4	0	14	0	14
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Integrin beta-3	10	2	1	13
Integrin alpha-IIb	10	2	1	13
Neuronal acetylcholine receptor subunit alpha-4	0	5	0	5
Serine/threonine-protein kinase pim-1	0	1	4	5
Neuronal acetylcholine receptor subunit beta-2	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	23	9	1	33
Gamma-aminobutyric acid receptor subunit delta	23	9	1	33
Gamma-aminobutyric acid receptor subunit gamma-2	23	9	2	34
Casein kinase II subunit alpha'	0	1	4	5
Gamma-aminobutyric acid receptor subunit alpha-5	23	9	1	33
Gamma-aminobutyric acid receptor subunit alpha-3	23	9	1	33
Gamma-aminobutyric acid receptor subunit gamma-1	23	9	1	33
Gamma-aminobutyric acid receptor subunit alpha-2	23	9	1	33
Proteinase-activated receptor 1	0	1	1	3
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	2
5-hydroxytryptamine receptor 2A	0	13	0	13
5-hydroxytryptamine receptor 2C	0	15	0	15
Gamma-aminobutyric acid receptor subunit alpha-4	23	9	1	33
Gamma-aminobutyric acid receptor subunit gamma-3	23	9	1	33
Gamma-aminobutyric acid receptor subunit alpha-6	23	9	1	33
Sodium-dependent serotonin transporter	0	10	2	13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	14	0	14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	4	3	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	3	3	8
Serine/threonine-protein kinase mTOR	0	4	3	7
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	14	2	0	18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	3	7
Glycogen synthase kinase-3 beta	0	1	4	5
D(1A) dopamine receptor	6	0	0	6
Serine/threonine-protein kinase PLK1	0	2	4	6
Gamma-aminobutyric acid receptor subunit alpha-1	23	11	2	36
Gamma-aminobutyric acid receptor subunit beta-3	23	9	1	33
Gamma-aminobutyric acid receptor subunit beta-2	23	9	2	34
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	3	4
DNA-dependent protein kinase catalytic subunit	0	4	0	4
Mu-type opioid receptor	0	8	1	9
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Serine/threonine-protein kinase ATR	0	1	2	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	3	4
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	23	9	1	33
Gamma-aminobutyric acid receptor subunit epsilon	23	9	1	33
Serine/threonine-protein kinase PLK3	0	2	3	5
Serine/threonine-protein kinase PLK2	0	1	3	4
ATP-dependent phosphofructokinase	25	0	0	25
Amyloid-beta precursor protein	2	4	0	6
Sodium-dependent dopamine transporter	0	14	1	15
retinoid X nuclear receptor alpha	35	0	0	35
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	29	0	0	29
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
thyroid hormone receptor beta isoform 2	46	0	0	46
Cellular tumor antigen p53	42	0	0	42
Sulfotransferase 1A1	0	0	0	2
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Sulfotransferase 2A1	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	33	0	0	33
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	21	0	0	21
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
phosphopantetheinyl transferase	29	0	0	29
USP1 protein, partial	20	0	0	20
Microtubule-associated protein tau	21	0	0	21
alpha-galactosidase	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	18	0	0	18
vitamin D3 receptor isoform VDRA	22	0	0	22
thyroid hormone receptor beta isoform a	17	0	0	17
DNA polymerase kappa isoform 1	19	0	0	19
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Metabotropic glutamate receptor 6	0	2	2	5
Glutamate receptor 1	2	10	2	18
Glutamate receptor 3	2	10	2	18
Glutamate receptor 4	2	10	2	18
Glutamate receptor ionotropic, kainate 1	0	9	2	13
Adenosine receptor A1	0	3	0	6
Glutamate receptor ionotropic, NMDA 1	0	16	2	24
Glutamate receptor ionotropic, kainate 1	0	5	1	6
Glutamate receptor ionotropic, kainate 2	0	9	1	12
Glutamate receptor 1	0	7	2	10
Glutamate receptor 2	0	6	2	9
Glutamate receptor 3	0	5	1	6
Glutamate receptor ionotropic, kainate 3	0	8	0	10
Glutamate receptor 4	0	6	1	8
D(2) dopamine receptor	0	13	1	14
Glutamate receptor ionotropic, NMDA 2A	0	14	2	22
Glutamate receptor ionotropic, NMDA 2B	0	14	2	22
Glutamate receptor ionotropic, NMDA 2C	0	14	2	22
Glutamate receptor ionotropic, kainate 4	0	8	0	10
Glutamate receptor ionotropic, kainate 2	0	5	1	6
Glutamate receptor ionotropic, kainate 3	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	14	2	22
Glutamate receptor ionotropic, kainate 5	0	8	1	11
Glutamate receptor ionotropic, NMDA 3B	0	14	2	22
Glutamate receptor ionotropic, NMDA 3A	0	14	2	22
interleukin 8	9	0	0	9
glucocorticoid receptor [Homo sapiens]	49	0	0	49
heat shock protein beta-1	10	0	0	10
mitogen-activated protein kinase 1	14	0	0	14
Nuclear receptor ROR-gamma	11	0	0	11
Peroxisome proliferator-activated receptor alpha	1	1	1	3
ATPase family AAA domain-containing protein 5	24	0	0	24
Ataxin-2	32	0	0	32
vitamin D (1,25- dihydroxyvitamin D3) receptor	25	0	0	25
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Chain A, JmjC domain-containing histone demethylation protein 3A	10	0	0	10
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
pyruvate kinase PKM isoform a	1	0	0	1
geminin	53	0	0	53
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	7	0	0	7
Tubulin--tyrosine ligase	0	2	0	2
lamin isoform A-delta10	55	0	0	55
PPM1D protein	10	0	0	10
Thymidylate synthase	0	1	0	2
Interferon beta	28	0	0	28
Canalicular multispecific organic anion transporter 1	0	2	0	3
Bloom syndrome protein isoform 1	20	0	0	20
potassium voltage-gated channel subfamily H member 2 isoform d	18	0	0	18
muscarinic acetylcholine receptor M1	17	0	0	17
lethal factor (plasmid)	15	0	0	15
Vesicular glutamate transporter 3	0	2	0	2
Trypsin	0	3	0	3
Coagulation factor VII	0	4	0	4
Tissue factor	0	5	0	5
Oxoeicosanoid receptor 1	0	2	0	2
GLS protein	23	0	0	23
Smad3	10	0	0	10
peripheral myelin protein 22	32	0	0	32
ATP-binding cassette sub-family C member 3	0	42	0	42
Multidrug resistance-associated protein 4	0	42	0	45
Solute carrier family 22 member 6	0	3	0	4
Carbonic anhydrase 12	0	3	0	6
UDP-glucuronosyltransferase 1A9	0	0	0	5
Bile salt export pump	0	7	0	7
Bile salt export pump	0	61	0	61
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	8	0	15
Carbonic anhydrase 2	0	8	1	16
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	1	1	3
Prostaglandin G/H synthase 1	0	5	0	5
Carbonic anhydrase 3	0	2	0	5
Cytochrome P450 3A4	0	15	2	20
Cytochrome P450 2D6	0	13	0	14
Cytochrome P450 2C9	0	17	0	17
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
UDP-glucuronosyltransferase 1-6	0	1	0	4
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 4	0	4	0	7
Prostaglandin G/H synthase 1	0	8	0	9
Carbonic anhydrase 6	0	2	0	5
Carbonic anhydrase 5A, mitochondrial	0	2	0	5
Prostaglandin G/H synthase 2	0	7	5	15
Carbonic anhydrase 7	0	2	0	5
Cytochrome P450 2J2	0	8	0	8
Carbonic anhydrase 9	0	4	0	7
Canalicular multispecific organic anion transporter 1	0	42	0	43
Carbonic anhydrase 15	0	4	0	7
Carbonic anhydrase 13	0	1	0	3
Carbonic anhydrase 14	0	2	0	5
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
toxin B	0	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, Ferritin light chain	9	0	0	9
Thymidine kinase	0	1	0	1
arylsulfatase A	18	0	0	18
activating transcription factor 6	21	0	0	21
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	8	0	0	8
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
Solute carrier family 22 member 1	0	11	0	16
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	4
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	6	1	0	7
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	1	0	5
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	5
Thymidine kinase	0	2	0	2
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	4
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	2	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	6	4	10
Amine oxidase [flavin-containing] B	0	2	0	2
5'-nucleotidase	0	1	0	2
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	0	1	1
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	4	4
Adenylate kinase 2, mitochondrial	0	0	4	5
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	6
Adenosine deaminase-like protein	0	0	0	1
Protease	0	1	1	2
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	1	2
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	5	5
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	4
Proton-coupled amino acid transporter 1	0	4	0	5
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	5
IDH1	17	0	0	17
transcriptional regulator ERG isoform 3	7	0	0	7
ras-related protein Rab-9A	7	0	0	7
Polyphenol oxidase 2	0	2	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
TAR DNA-binding protein 43	11	0	0	11
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	2
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	0	1
Excitatory amino acid transporter 1	0	4	0	5
Excitatory amino acid transporter 2	0	4	0	5
Excitatory amino acid transporter 3	0	4	0	5
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
Methylcytosine dioxygenase TET2	0	2	1	3
nuclear receptor ROR-gamma isoform 1	14	0	0	14
Gamma-aminobutyric acid receptor subunit alpha-1	0	9	4	13
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	2	10
Cholecystokinin receptor type A	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	9	4	13
Gamma-aminobutyric acid receptor subunit alpha-3	0	9	3	12
Gamma-aminobutyric acid receptor subunit alpha-2	0	9	3	12
Gamma-aminobutyric acid receptor subunit beta-2	0	9	2	11
Cholecystokinin receptor type A	0	1	0	1
acetylcholinesterase	23	0	0	23
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
putative alpha-glucosidase	1	0	0	1
Solute carrier family 22 member 2	0	4	0	7
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	30	0	1	31
Solute carrier family 22 member 1	0	3	0	4
Multidrug and toxin extrusion protein 1	0	7	0	7
Solute carrier family 22 member 2	0	2	0	3
Chain A, Beta-lactamase	11	0	0	11
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
apical membrane antigen 1, AMA1	7	0	0	7
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	16	0	0	16
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase	0	0	0	3
Kappa-type opioid receptor	0	6	0	9
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	4	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
tumor necrosis factor	2	0	0	2
Cytochrome P450 2C19	0	7	0	7
Potassium voltage-gated channel subfamily H member 2	0	19	0	20
Aurora kinase B	0	2	4	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	8	1	11
D(1A) dopamine receptor	11	0	0	11
neuropeptide S receptor isoform A	6	0	0	6
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
thioredoxin glutathione reductase	6	0	0	6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	4	0	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Aromatase	0	5	0	5
Fatty acid-binding protein, adipocyte	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Calmodulin	0	0	0	1
Prostaglandin G/H synthase 2	0	6	0	7
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	2	0	2
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Solute carrier organic anion transporter family member 1B3	0	8	0	10
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	7	0	9
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	36	0	0	36
nuclear factor erythroid 2-related factor 2 isoform 2	21	0	0	21
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	15	2	17
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	1	1	3
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	2	0	2
Metabotropic glutamate receptor 1	0	2	2	5
Metabotropic glutamate receptor 2	0	2	3	6
Carbonic anhydrase-like protein, putative	0	0	0	5
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	2	0	0	2
cytochrome P450 2D6	28	0	0	28
glucocerebrosidase	6	0	0	6
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Epidermal growth factor receptor	0	13	5	18
Fatty acid-binding protein, liver	0	5	0	5
Myeloperoxidase	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A2a	0	1	1	5
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	11	1	12
Sigma non-opioid intracellular receptor 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Caspase-7	3	0	0	3
Inositol monophosphatase 1	12	0	0	12
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
G	19	0	0	19
thyrotropin-releasing hormone receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	19	0	0	19
Inositol hexakisphosphate kinase 1	19	0	0	19
cytochrome P450 2C9, partial	19	0	0	19
pregnane X receptor	10	0	0	10
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine phosphorylase	0	0	1	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Kappa-type opioid receptor	0	7	2	10
Matrix metalloproteinase-9	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	4	3	7
Aldo-keto reductase family 1 member B1	0	11	0	11
Adenosine receptor A3	0	4	0	4
Beta-3 adrenergic receptor	0	4	0	4
Alpha-1B adrenergic receptor	0	11	1	12
5-hydroxytryptamine receptor 1A	0	18	3	21
Sodium-dependent noradrenaline transporter	0	18	2	20
Thromboxane-A synthase	0	1	0	1
Type-1A angiotensin II receptor	0	1	1	2
Type-1 angiotensin II receptor	0	3	0	5
Alpha-1A adrenergic receptor	0	13	2	15
Type-2 angiotensin II receptor	0	2	0	2
Leukotriene B4 receptor 2	0	1	1	2
Protein phosphatase 1B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	0	1	0	1
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B	0	1	0	1
Liver carboxylesterase 1	0	1	0	5
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
Acetylcholinesterase	0	7	0	7
Cannabinoid receptor 2	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Metallo-beta-lactamase type 2	0	1	1	4
peripheral myelin protein 22 isoform 1	10	0	0	10
Prothrombin	0	1	1	3
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	4	1	5
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	4	1	5
Angiotensin-converting enzyme	0	6	0	7
Leukotriene A-4 hydrolase	0	1	0	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	4	0	4
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	1	2
Beta-lactamase class B VIM-2	0	1	1	4
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	1	0	2
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
5-hydroxytryptamine receptor 2C	0	10	1	12
5-hydroxytryptamine receptor 2A	0	10	1	11
5-hydroxytryptamine receptor 1B	0	12	1	13
5-hydroxytryptamine receptor 1D	0	5	1	6
5-hydroxytryptamine receptor 1F	0	5	1	6
5-hydroxytryptamine receptor 2B	0	8	1	9
5-hydroxytryptamine receptor 6	0	3	1	4
5-hydroxytryptamine receptor 7	0	6	1	7
5-hydroxytryptamine receptor 5A	0	3	1	4
5-hydroxytryptamine receptor 5B	0	3	1	4
5-hydroxytryptamine receptor 3A	0	6	1	7
5-hydroxytryptamine receptor 4	0	4	1	6
5-hydroxytryptamine receptor 3B	0	6	1	7
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase VIM-1	0	0	0	2
Beta-lactamase	0	0	0	1
Albumin	0	1	4	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 7	0	1	0	2
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
glp-1 receptor, partial	15	0	0	15
caspase 7, apoptosis-related cysteine protease	9	0	0	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
caspase-3	9	0	0	9
thyroid stimulating hormone receptor	15	0	0	15
Caspase-7	5	0	0	5
interferon gamma precursor	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
caspase-3	5	0	0	5
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	6	0	6
3-phosphoinositide-dependent protein kinase 1	0	1	3	4
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Procathepsin L	0	2	1	3
Quinolone resistance protein NorA	0	3	0	3
Calpain-2 catalytic subunit	0	1	0	1
D(1A) dopamine receptor	0	8	0	8
Prostaglandin G/H synthase 1	0	1	0	1
Cruzipain	0	3	0	3
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sodium-dependent serotonin transporter	0	17	3	20
Delta-type opioid receptor	0	5	0	6
Delta-type opioid receptor	0	8	1	10
Mu-type opioid receptor	0	8	2	13
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase	0	3	0	6
Carbonic anhydrase	0	1	0	4
Histone deacetylase 4	0	5	0	5
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Histone deacetylase 1	0	7	0	7
Mitogen-activated protein kinase 14	0	3	5	8
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase	0	1	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	2
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	5	0	5
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	6	0	6
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	5	0	5
Histone deacetylase 8	0	6	0	6
P2Y purinoceptor 12	0	1	0	1
Histone deacetylase 6	0	6	0	6
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	5	0	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	3	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
endonuclease IV	7	0	0	7
Voltage-dependent L-type calcium channel subunit alpha-1F	0	10	0	10
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	10	0	10
Voltage-dependent L-type calcium channel subunit alpha-1S	0	10	0	10
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	10
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
Sodium-dependent noradrenaline transporter	0	1	0	1
Tryptophan 5-hydroxylase 1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	3	0	3
Aromatase	0	1	0	1
Sodium-dependent dopamine transporter	0	8	2	10
Alpha-1D adrenergic receptor	0	12	1	13
Histamine H1 receptor	0	10	0	10
5-hydroxytryptamine receptor 7	0	5	0	5
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Transporter	0	9	0	9
importin subunit beta-1 isoform 1	7	0	0	7
mitogen-activated protein kinase kinase kinase kinase 2 isoform 1	0	0	1	1
eyes absent homolog 2 isoform a	2	0	0	2
snurportin-1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
streptokinase A precursor	0	0	2	2
mitogen-activated protein kinase kinase kinase 3 isoform 1	0	0	1	1
Estrogen receptor	0	0	2	2
ATP-dependent translocase ABCB1	0	11	1	16
Spike glycoprotein	0	0	1	1
C-terminal-binding protein 1	1	0	0	1
Estrogen receptor beta	0	0	2	2
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	8	1	9
Translocator protein	0	2	0	2
Translocator protein	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	8	0	8
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	8	0	8
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	2	0	2
5-hydroxytryptamine receptor 1A	0	5	4	9
Alpha-2A adrenergic receptor	0	14	2	16
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	12	1	13
D	0	7	0	7
D(3) dopamine receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	7	1	8
Amine oxidase [flavin-containing] A	0	3	0	3
Alpha-2C adrenergic receptor	0	7	1	8
Alpha-2A adrenergic receptor	0	7	1	8
Alpha-1D adrenergic receptor	0	7	1	8
D(1B) dopamine receptor	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
Adenosine receptor A2b	0	0	1	1
Alpha-2B adrenergic receptor	0	0	0	1
D(4) dopamine receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	5	1	6
Alpha-1B adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Nischarin	0	2	0	2
nonstructural protein 1	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 2B6	0	3	0	3
P2Y purinoceptor 12	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Lysosomal Pro-X carboxypeptidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	1
dopamine D1 receptor	7	0	0	7
Glucocorticoid receptor	0	8	2	15
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	4	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	4	6
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	3
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Isocitrate lyase	0	1	0	1
Leukotriene C4 synthase	0	0	3	3
Fumarate hydratase	11	0	0	11
GALC protein	3	0	0	3
polyprotein	11	0	0	11
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
huntingtin isoform 2	8	0	0	8
tyrosine-protein kinase Yes	4	0	0	4
Bone morphogenetic protein receptor type-1B	0	0	4	4
Membrane-associated progesterone receptor component 1	0	0	3	3
Serine/threonine-protein kinase 25	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	4	4
Pyridoxal kinase	0	0	4	5
Citron Rho-interacting kinase	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	3	3
Serine/threonine-protein kinase Chk1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	3	4
Peripheral plasma membrane protein CASK	0	0	3	3
Aurora kinase A	0	1	4	5
Cyclin-G-associated kinase	0	1	4	5
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	3	4
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
Mitogen-activated protein kinase 13	0	2	3	5
Transmembrane protease serine 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	2	4	6
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
NUAK family SNF1-like kinase 1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	4	4
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	4	4
Serine/threonine-protein kinase ULK1	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	4	4
Ribosomal protein S6 kinase alpha-5	0	0	4	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	4	4
Serine/threonine-protein kinase 16	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Cyclin-dependent kinase-like 5	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	3	3
Serine/threonine-protein kinase 10	0	0	4	4
Serine/threonine-protein kinase D3	0	0	4	4
Cyclin-dependent kinase 14	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	4	4
Serine/threonine-protein kinase LATS1	0	0	4	4
Serine/threonine-protein kinase PAK 4	0	0	4	4
Serine/threonine-protein kinase Chk2	0	0	3	3
Tyrosine-protein kinase ABL1	0	7	7	15
Tyrosine-protein kinase ABL1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Transthyretin	0	2	1	4
RAF proto-oncogene serine/threonine-protein kinase	0	2	4	7
High affinity nerve growth factor receptor	0	0	4	4
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	4	4
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Protein kinase C beta type	0	0	4	4
Insulin receptor	0	2	4	6
Tyrosine-protein kinase Lck	0	4	4	8
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Tyrosine-protein kinase Fyn	0	3	4	7
Cyclin-dependent kinase 1	0	1	4	5
Glycogen phosphorylase, liver form	0	0	4	4
Tyrosine-protein kinase Fes/Fps	0	0	4	4
Macrophage colony-stimulating factor 1 receptor	0	3	3	6
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	1	4	5
Tyrosine-protein kinase Lyn	0	1	4	5
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	4	7
Insulin-like growth factor 1 receptor	0	2	4	6
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	0	4	4
Tyrosine-protein kinase HCK	0	3	4	7
Proto-oncogene tyrosine-protein kinase ROS	0	0	3	3
Platelet-derived growth factor receptor beta	0	3	4	7
Tyrosine-protein kinase Fgr	0	0	4	4
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	2	1	3
Serine/threonine-protein kinase A-Raf	0	1	4	5
Mast/stem cell growth factor receptor Kit	0	3	4	7
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	2	6	9
Fibroblast growth factor receptor 1	0	2	4	7
Myosin light chain kinase, smooth muscle	0	0	3	3
Cyclin-dependent kinase 4	0	0	4	4
ADP/ATP translocase 3	0	0	4	4
Inosine-5'-monophosphate dehydrogenase 2	0	2	4	6
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Insulin receptor-related protein	0	0	3	3
Serine/threonine-protein kinase B-raf	0	2	5	8
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	4	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	4	6
Platelet-derived growth factor receptor alpha	0	3	4	7
Tyrosine-protein kinase Blk	0	1	0	1
Tyrosine-protein kinase Fer	0	0	4	4
Protein kinase C alpha type	0	1	4	5
cAMP-dependent protein kinase catalytic subunit alpha	0	0	4	4
Vascular endothelial growth factor receptor 1	0	1	3	4
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Ras-related protein Rab-6A	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	3	3
Cyclin-dependent kinase 11B	0	0	3	3
Ephrin type-A receptor 1	0	0	4	4
Fibroblast growth factor receptor 2	0	0	3	3
Receptor tyrosine-protein kinase erbB-3	0	1	3	4
Multifunctional protein ADE2	0	0	4	4
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
cAMP-dependent protein kinase catalytic subunit gamma	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	4	4
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	4	4
Tyrosine-protein kinase JAK1	0	0	4	4
Protein kinase C eta type	0	0	3	3
Cyclin-dependent kinase 2	0	1	5	6
Beta-adrenergic receptor kinase 1	0	0	4	4
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Activin receptor type-2A	0	0	3	3
Mitogen-activated protein kinase 3	0	0	4	4
MAP/microtubule affinity-regulating kinase 3	0	0	4	4
Mitogen-activated protein kinase 1	0	0	4	4
Ephrin type-A receptor 2	0	1	4	5
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Ephrin type-B receptor 2	0	1	4	5
Leukocyte tyrosine kinase receptor	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	0	4	4
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	4	4
Wee1-like protein kinase	0	0	4	4
Heme oxygenase 2	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	0	3	3
Mitogen-activated protein kinase 4	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-alpha serine/threonine-protein kinase	0	1	4	5
RAC-beta serine/threonine-protein kinase	0	1	4	5
G protein-coupled receptor kinase 4	0	0	3	3
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	4	4
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Vascular endothelial growth factor receptor 3	0	1	3	4
Vascular endothelial growth factor receptor 2	0	4	3	7
Dual specificity mitogen-activated protein kinase kinase 2	0	2	4	6
Receptor-type tyrosine-protein kinase FLT3	0	1	4	5
Bone morphogenetic protein receptor type-1A	0	0	4	4
Activin receptor type-1B	0	0	4	4
TGF-beta receptor type-1	0	0	4	4
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	4	4
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	1	4	5
Glycine--tRNA ligase	0	0	4	4
Protein kinase C iota type	0	0	4	4
Exosome RNA helicase MTR4	0	0	4	4
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase Tec	0	1	4	5
Tyrosine-protein kinase TXK	0	1	3	4
Tyrosine-protein kinase ABL2	0	1	4	5
Tyrosine-protein kinase FRK	0	0	4	4
G protein-coupled receptor kinase 6	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	3	3
Tyrosine-protein kinase SYK	0	1	4	5
26S proteasome regulatory subunit 6B	0	0	4	4
Mitogen-activated protein kinase 8	0	0	4	4
Mitogen-activated protein kinase 9	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	4	4
Casein kinase I isoform alpha	0	2	4	6
Casein kinase I isoform delta	0	0	4	4
Cyclin-dependent kinase 8	0	0	3	3
Elongation factor Tu, mitochondrial	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	4	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	0	4	4
Dual specificity protein kinase CLK2	0	0	4	4
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	4	4
Cyclin-dependent kinase 7	0	0	4	4
Cyclin-dependent kinase 9	0	0	4	4
Ras-related protein Rab-27A	0	0	4	4
Tyrosine-protein kinase Blk	0	1	3	4
Interleukin-1 receptor-associated kinase 1	0	0	4	4
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Ribosomal protein S6 kinase alpha-3	0	1	4	5
Cytoplasmic tyrosine-protein kinase BMX	0	0	3	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	4	4
Serine/threonine-protein kinase Nek3	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	3	3
Tyrosine-protein kinase JAK3	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 6	0	0	4	4
Death-associated protein kinase 1	0	0	3	3
LIM domain kinase 1	0	1	4	5
LIM domain kinase 2	0	1	4	5
Mitogen-activated protein kinase 12	0	2	3	5
Mitogen-activated protein kinase 10	0	0	4	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	4	4
Ephrin type-B receptor 3	0	0	4	4
Ephrin type-A receptor 5	0	0	4	4
Ephrin type-B receptor 4	0	2	4	6
Ephrin type-B receptor 1	0	0	3	3
Ephrin type-A receptor 4	0	0	4	4
Adenosine kinase	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	2	3	5
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Ras-related protein Rab-10	0	0	4	4
Cell division control protein 2 homolog	0	0	3	3
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
Calcium-dependent protein kinase 1	0	0	3	3
GTP-binding nuclear protein Ran	0	0	4	4
Tubulin alpha-1A chain	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Casein kinase I isoform gamma-2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	3	3
Cyclin-dependent kinase 6	0	0	4	4
Cyclin-dependent-like kinase 5	0	0	4	4
Cyclin-dependent kinase 16	0	0	4	4
Cyclin-dependent kinase 17	0	0	4	4
Myelin transcription factor 1	0	1	0	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Protein kinase C epsilon type	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 1	0	2	4	6
Angiopoietin-1 receptor	0	1	3	4
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
DNA topoisomerase 2-beta	0	1	5	12
Protein kinase C theta type	0	0	4	4
Activin receptor type-1	0	0	4	4
Macrophage-stimulating protein receptor	0	1	4	5
Focal adhesion kinase 1	0	1	4	5
Protein kinase C zeta type	0	1	3	4
Protein kinase C delta type	0	1	4	5
Tyrosine-protein kinase BTK	0	2	4	6
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	3	3
Activated CDC42 kinase 1	0	1	4	5
Epithelial discoidin domain-containing receptor 1	0	3	4	7
Tyrosine-protein kinase ITK/TSK	0	1	3	4
Myotonin-protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Tyrosine-protein kinase Mer	0	0	4	4
Serine/threonine-protein kinase 4	0	0	4	4
Serine/threonine-protein kinase PAK 1	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase 7	0	0	4	4
Serine/threonine-protein kinase PAK 2	0	0	4	4
Serine/threonine-protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 1	0	0	4	4
cGMP-dependent protein kinase 2	0	0	3	3
Integrin-linked protein kinase	0	0	4	4
Rho-associated protein kinase 1	0	0	4	4
Non-receptor tyrosine-protein kinase TNK1	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	4	4
Activin receptor type-2B	0	0	4	4
Bone morphogenetic protein receptor type-2	0	0	4	4
Protein-tyrosine kinase 6	0	1	4	5
cGMP-dependent protein kinase 1	0	0	4	4
Cyclin-dependent kinase 13	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	4	4
Protein-tyrosine kinase 2-beta	0	0	4	4
Sodium channel protein type 5 subunit alpha	0	7	0	7
Maternal embryonic leucine zipper kinase	0	0	4	4
Structural maintenance of chromosomes protein 1A	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Serine/threonine-protein kinase D1	0	0	3	3
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	1	3	4
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Ephrin type-A receptor 7	0	0	3	3
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	1	4	5
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	4	4
Mitogen-activated protein kinase 11	0	2	4	6
Serine/threonine-protein kinase STK11	0	0	4	4
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
Serine/threonine-protein kinase N1	0	0	4	4
Serine/threonine-protein kinase N2	0	0	4	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	4	4
Mitogen-activated protein kinase kinase kinase 11	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Discoidin domain-containing receptor 2	0	2	4	6
AP2-associated protein kinase 1	0	0	4	4
Myosin light chain kinase 3	0	0	4	4
Uncharacterized aarF domain-containing protein kinase 5	0	0	4	4
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase MRCK alpha	0	0	4	4
Serine/threonine-protein kinase MRCK gamma	0	0	4	4
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase Nek5	0	0	3	3
Serine/threonine-protein kinase N3	0	0	4	4
Breakpoint cluster region protein	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	4	4
Dual serine/threonine and tyrosine protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	4	4
Serine/threonine-protein kinase MARK2	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	4	4
STE20-related kinase adapter protein alpha	0	0	4	4
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	4	4
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	3	3
Misshapen-like kinase 1	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	0	3	3
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	4	4
Mitogen-activated protein kinase 15	0	0	4	4
Serine/threonine-protein kinase Nek9	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	4	4
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	4	4
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
MAP/microtubule affinity-regulating kinase 4	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	4	4
Cyclin-dependent kinase 15	0	0	3	3
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	4	4
EKC/KEOPS complex subunit TP53RK	0	0	4	4
Dual specificity testis-specific protein kinase 2	0	0	2	2
SRSF protein kinase 1	0	0	3	3
Protein cereblon	0	2	2	6
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	4	6
Mitogen-activated protein kinase kinase kinase 5	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	4	4
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	0	3	3
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase 33	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	1	4	5
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO3	0	0	4	4
Homeodomain-interacting protein kinase 2	0	0	3	3
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	0	3	3
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase Nek6	0	0	3	3
Casein kinase I isoform gamma-1	0	0	4	4
Serine/threonine-protein kinase PAK 6	0	0	3	3
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	4	4
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	1	4	5
Cyclin-dependent kinase 12	0	0	4	4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	4	4
Serine/threonine-protein kinase PAK 5	0	0	3	3
Serine/threonine-protein kinase 26	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	4	4
Serine/threonine-protein kinase NLK	0	0	4	4
Phosphatidylinositol 4-kinase beta	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
Serine/threonine-protein kinase TBK1	0	0	4	4
Septin-9	0	0	4	4
Death-associated protein kinase 2	0	0	3	3
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	4	4
TRAF2 and NCK-interacting protein kinase	0	0	4	4
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	4	4
ALK tyrosine kinase receptor	0	0	3	3
SRSF protein kinase 3	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	4	4
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	1	4	5
Serine/threonine-protein kinase 38-like	0	0	4	4
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase SIK3	0	1	4	5
Mitogen-activated protein kinase kinase kinase 2	0	0	4	4
Thyroid hormone receptor-associated protein 3	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 3	0	0	4	4
Serine/threonine-protein kinase MRCK beta	0	0	4	4
Interleukin-1 receptor-associated kinase 3	0	0	4	4
Serine/threonine-protein kinase 24	0	0	3	3
NF-kappa-B essential modulator	0	1	0	1
Casein kinase I isoform gamma-3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 4	0	0	4	4
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	2	0	2
DNA topoisomerase 2-alpha	0	1	4	12
Carbonyl reductase [NADPH] 1	0	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	2	0	4
Reverse transcriptase/RNaseH	0	1	1	2
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Deoxyhypusine hydroxylase	0	1	0	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	1
Gamma-aminobutyric acid	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	3	3
Translocator protein	0	3	2	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	4
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Chain A, limonene-1,2-epoxide hydrolase	0	1	0	1
Chain A, Epoxide hydrolase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	6
UDP-glucuronosyltransferase 1A7	0	0	0	2
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Peroxisome proliferator-activated receptor gamma	0	1	5	6
Endothelin-1 receptor	0	2	0	2
Serine/threonine-protein kinase B-raf	0	2	0	2
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	4	0	4
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	2	0	2
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	2
Sodium/bile acid cotransporter	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(2) dopamine receptor	0	10	1	11
D(4) dopamine receptor	0	5	0	5
Kappa-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	8	3	12
D(3) dopamine receptor	0	11	0	11
Delta-type opioid receptor	0	6	2	9
Mu-type opioid receptor	0	3	2	7
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Adenosine receptor A3	0	1	0	1
Adenosine deaminase	0	0	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	1	0	0	1
muscleblind-like protein 1 isoform 1	6	0	0	6
Solute carrier family 22 member 8	0	0	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	2	0	0	2
DNA polymerase beta	3	0	0	3
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	4	4	9
Aldo-keto reductase family 1 member B1	0	1	0	1
Alpha-synuclein	3	0	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
P-selectin	0	1	0	1
epidermal growth factor receptor isoform a precursor	1	1	0	2
Cell division cycle 7-related protein kinase	0	0	2	2
Cytochrome P450 2E1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Beta-secretase 1	0	1	0	1
Synaptic vesicular amine transporter	0	4	1	5
Transcription factor p65	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	6	0	6
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	2	2	4
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 5	0	2	1	4
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	2
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	2	2	5
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	4	4
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	7	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
trace amine-associated receptor 1	0	1	1	2
Chain A, ELONGATION FACTOR TU (EF-TU)	0	0	1	1
Chain A, Elongation Factor G	0	0	1	1
Chain A, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3	0	0	1	1
Chain A, Eukaryotic peptide chain release factor GTP-binding subunit	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, Elongation factor 2	0	0	1	1
Chain A, Guanine nucleotide-binding protein G(i), alpha-1 subunit	0	0	1	1
Matrilysin	0	2	0	2
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	3
Histidine-binding periplasmic protein	0	0	1	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 3A5	0	2	0	3
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	2	1	3
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Phospholipase A-2-activating protein	0	2	0	2
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
phosphoglycerate kinase	1	0	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	4	0	4
5-hydroxytryptamine receptor 1A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
C-C chemokine receptor type 5	0	1	2	4
C-C chemokine receptor type 5	0	1	0	1
C-C chemokine receptor type 5	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
ClpP	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Cholinesterase	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Cytochrome P450 1B1	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	2	0	2
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Protein-arginine deiminase type-4	0	3	0	3
tumor susceptibility gene 101 protein	1	0	0	1
Serine racemase	0	1	0	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
5-hydroxytryptamine receptor 3E	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 3A	0	2	1	3
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	1	2
5-hydroxytryptamine receptor 3C	0	1	1	2
5-hydroxytryptamine receptor 3B	0	3	0	3
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Muscarinic acetylcholine receptor M2	0	7	0	7
Muscarinic acetylcholine receptor M4	0	7	0	7
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	7	0	7
Muscarinic acetylcholine receptor M1	0	7	0	7
Muscarinic acetylcholine receptor M3	0	8	0	8
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	6	0	6
Histamine H1 receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	4	0	4
5-hydroxytryptamine receptor 6	0	6	0	7
G-protein coupled receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	1	3
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Kappa-type opioid receptor	0	2	2	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
Interstitial collagenase	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Tumor necrosis factor	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
Sodium channel protein type 2 subunit alpha	0	2	0	2
Fatty acid-binding protein, liver	0	1	0	1
DNA polymerase III, partial	2	0	0	2
XBP1	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
WD repeat-containing protein 48	0	1	0	1
Histamine H4 receptor	0	1	0	1
Hsf1 protein	0	0	1	2
histone deacetylase 9 isoform 3	2	0	0	2
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Pirin	0	1	0	1
GTPase KRas	0	1	0	1
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Heat shock factor protein 1	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Cyclin-dependent kinase 10	0	0	1	1
Rab-like protein 3	0	0	2	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	1	2	3
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
Riboflavin-binding protein	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Transporter	0	1	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
Lysine-specific demethylase 4E	0	1	0	1
Delta-aminolevulinic acid dehydratase	0	1	0	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Solute carrier family 13 member 3	0	1	0	1
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Thromboxane A2 receptor	0	0	0	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	1	1	2
polyadenylate-binding protein 1	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	1	2
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
serine/threonine-protein kinase PLK1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Endolysin	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Taste receptor type 2 member 14	0	0	0	1
RGS12	1	0	0	1
PINK1	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
D(3) dopamine receptor isoform e	1	0	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Kinesin-1 heavy chain	0	1	0	1
Coiled-coil domain-containing protein 6	0	1	0	1
ATP-dependent RNA helicase DHX30	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(13)

Research Excerpts

Overview

Context

Treatment

Research

Studies (480)

Protein Targets (1,868)

CACH Syndrome

Synonyms(13)

Research Excerpts

Overview

Context

Treatment

Research

Studies (480)

Drugs Studied (285)

Protein Targets (1,868)