4-aminophthalimide

Description

4-Aminophthalimide (4-AP) is a fluorescent compound that has gained significant attention for its diverse applications in various fields. Its synthesis typically involves the reaction of phthalic anhydride with ammonia, followed by a subsequent nitration and reduction process. 4-AP exhibits strong fluorescence properties with high quantum yield and excellent photostability, making it suitable for use in fluorescence microscopy, sensing, and bioimaging. Its sensitivity to environmental changes, such as pH and temperature, has led to its utilization in developing fluorescent probes and biosensors. Furthermore, 4-AP derivatives have shown potential as therapeutic agents, demonstrating anticancer and antibacterial activities. The unique structural features and fluorescence properties of 4-AP continue to drive research efforts to explore its potential in various applications, including materials science, biomedicine, and environmental monitoring.'

4-aminophthalimide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

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