Apolipoprotein B-100, Familial Defective

Type IIb hyperlipoproteinemia is caused by mutation in the receptor-binding domain of APOLIPOPROTEIN B-100 which is a major component of LOW-DENSITY LIPOPROTEINS and VERY-LOW-DENSITY LIPOPROTEINS resulting in reduced clearance of these lipoproteins. It is characterized by both hypercholesterolemia and HYPERTRIGLYCERIDEMIA (combined hyperlipidemia).

Synonym
Familial Combined Hyperlipoproteinemia
LDL Receptor Disorder
Apolipoprotein B-100, Familial Ligand-Defective
Apolipoprotein B-100, Familial Defective
Hyperlipoproteinemia Type IIa
Hyperlipoproteinemia Type IIb
Hyper-Low Density Lipoproteinemia
Hyperlipoproteinemia, Type IIa
Hyper-Low-Density-Lipoproteinemia
Hypercholesterolemic Xanthomatosis, Familial
Hypercholesterolemia, Familial
Hyperlipoproteinemia, Type II
Hypercholesterolemia, Essential
Hypercholesterolemia, Autosomal Dominant, Type B
Hyper-beta-Lipoproteinemia
Hyperbetalipoproteinemia
Hyperlipoproteinemia Type 2
Hypercholesterolemia, Autosomal Dominant

Excerpt	Reference
"Homozygous familial hypercholesterolemia is refractory to standard dietary or drug therapy."	( Burr, IM; Greene, HL; Slonim, AE; Stacpoole, PW; Swift, LL; Younger, RK, 1982)
"Screening for familial hypercholesterolemia is defensible because of (1) the serious prognosis and relatively high prevalence of familial hypercholesterolemia, (2) the existence of appropriate initial screening and follow-up diagnostic tests, (3) the fact that family history-directed screening is likely to be effective in detecting affected individuals, and (4) the apparent effectiveness of intervention in adolescence for a disease that would otherwise manifest in early adulthood."	( Gillman, MW, 1993)
"Pseudohomozygous familial hypercholesterolemia is a rare condition of unknown etiology."	( Miyazaki, K; Naito, M; Yoshida, A, 2000)
"Homozygous familial hypercholesterolemia is a rare hypercholesterolemia representing 1 to 2% of hypercholesterolemia."	( Ahmed-Nasr, M; Ayegnon, KG; Morcos, KK; Yangni-Angate, KH, 2009)
"Background Familial hypercholesterolemia is a common autosomal dominant disease, caused by mutations leading to elevated low-density lipoprotein (LDL) cholesterol and, if untreated, to premature cardiovascular disease."	( De Simone, B; Di Taranto, MD; Fortunato, G; Gentile, M; Giacobbe, C; Iannuzzi, A; Iannuzzo, G; Jossa, F; Marotta, G; Rubba, P; Sodano, M, 2017)
"Among them, familial hypercholesterolemia is the most common lipid disorder that predisposes for premature cardiovascular disease."	( Arca, M; Averna, M; Bertolini, S; Calandra, S; Casula, M; Catapano, AL; Cefalù, AB; Noto, D; Tarugi, P, 2017)
"The genetic cause of familial hypercholesterolemia is unknown in 20%-40% of the cases."	( Ivanoshchuk, D; Mikhailova, S; Shakhtshneider, E; Timoshchenko, O, 2019)

Excerpt	Reference
"Patients with familial hypercholesterolemia have a high incidence of coronary heart disease due to diet- and drug-resistant, elevated low-density lipoprotein cholesterol (LDL-C)."	( Koch, KM; Olbricht, CJ; Schulzeck, P, 1992)
"Patients with familial hypercholesterolemia have elevated levels of plasma low density lipoproteins (LDL), increased hepatic synthesis of apolipoprotein B-containing lipoproteins, defective binding of low density lipoproteins to fibroblasts, and premature atherosclerosis."	( Brewer, HB; Demosky, SJ; Hoeg, JM; Schaefer, EJ; Starzl, TE, 1984)
"Children with familial hypercholesterolemia have endothelial dysfunction and increased carotid intima-media thickness (IMT), which herald the premature atherosclerotic disease they develop later in life."	( Bakker, HD; Büller, HR; de Groot, E; Hutten, BA; Kastelein, JJ; Rodenburg, J; Sijbrands, EJ; Wiegman, A, 2004)
"Patients with familial hypercholesterolemia have an increased level of LDL cholesterol since childhood, and present early associated cardiovascular disease."	( Araujo, MB; Botto, PM; Mazza, CS, 2012)
"Children with familial hypercholesterolemia have greater mean carotid intima-media thickness (cIMT) than their unaffected siblings even before the age of 8 years, which is several years earlier than previously reported."	( Braamskamp, MJ; Hutten, BA; Wiegman, A, 2015)

Excerpt	Reference
"15 outpatients with type II hyperlipoproteinemia (7 with type IIa and 8 with type IIb) were treated with soybean."	( Bosia, C; Fragiacomo, C; Noseda, G; Ramelli, F; Sirtori, CR, 1979)
"A subgroup of patients with familial hypercholesterolemia (FH) respond inadequately to standard diet and drug therapy, and are therefore at high risk for the premature development or progression of coronary artery disease."	( Bilheimer, DW; Brown, DC; Dau, PC; Gordon, BR; Gotto, AM; Illingworth, DR; Jones, PH; Kelsey, SF; Leitman, SF; Prihoda, JS, 1992)
"Twenty eight patients with heterozygous familial hypercholesterolemia were treated with mevalonic acid (an inhibitor of cholesterol synthesis) for 45 days."	( Aloe, N; Augeri, C; Avola, F; Carta, G; Cavagnaro, A; De Grandi, R; Del Nero, E; Gianfreda, M; Magro, GP; Mazzarello, GP, 1992)
"In subjects with familial hypercholesterolemia cholesterol absorption efficiency was insignificantly reduced during a short-term more consistently during long-term pravastatin treatment."	( Miettinen, TA, 1991)
"Patients with heterozygous familial hypercholesterolemia (n = 12) were treated either with pravastatin, a specific inhibitor of HMG-CoA reductase, or cholestyramine, followed by a period of combined treatment with both drugs."	( Angelin, B; Berglund, L; Dallner, G; Elmberger, PG; Eriksson, M; Kalén, A; Lund, E; Reihnér, E, 1991)
"Seventeen patients with heterozygous familial hypercholesterolemia were sequentially treated with: a low cholesterol, fat restricted diet; diet and probucol (500 mg/day); and diet, probucol and niceritrol (1500 mg/day)."	( Fukushima, N; Ozaki, I; Sakai, T; Setoguchi, Y; Yamamoto, K; Yanagita, T, 1991)
"Two patients with familial hypercholesterolemia were treated by long-term plasma exchange via an arteriovenous Cimino shunt using unselective membrane separation."	( Arntz, HR; Keller, F; Passfall, J, 1990)
"Three patients with heterozygote type IIa hyperlipoproteinemia were treated by specific LDL apheresis with a dextran sulfate-cellulose column every two weeks."	( Delplanque, B; Duedari, N; Emmerich, J; Jacotot, B; Jourdan, D; Norol, F, 1988)
"Twelve patients suffering from familial hyperlipoproteinemia type IIa (FH) were treated for 8 months with simvastatin (20-40 mg/day) and compared with 10 untreated FH patients and 10 untreated normocholesterolemic subjects."	( Löbel, P; Schrör, K; Steinhagen-Thiessen, E, 1989)
"In 10 adult patients with severe type II hyperlipoproteinemia, a single HELP treatment of 3 1 plasma led to an acute decrease in the average plasma viscosity (PV) from 1."	( Armstrong, VW; Eisenhauer, T; Janning, G; Schuff-Werner, P; Schütz, E; Seidel, D; Seyde, WC, 1989)
"Eleven patients with heterozygous familial hypercholesterolemia (type IIa) were treated by partial ileal bypass."	( Keane, PF; Ohri, SK; Sackier, JM; Swift, I; Thompson, GR; Williamson, RC; Wood, CB, 1989)
"In patients with familial hypercholesterolemia treated with the bile acid sequestrant cholestyramine (16 gms/day), urinary mevalonate excretion increased by 28%, whereas low-density lipoprotein cholesterol concentrations decreased by 21%."	( Illingworth, DR; Pappu, AS, 1989)
"It is concluded that in familial hypercholesterolemia ileal bypass results in higher HDL- and HDL2-cholesterol and apoprotein A-I level than conservative treatment and that postheparin plasma lipolytic enzymes do not explain the higher level of these HDL components in the operated subjects."	( Koivisto, P; Kuusi, T; Miettinen, TA, 1987)
"However, in some patients with familial hypercholesterolemia, treatment was associated with a rebound in serum cholesterol concentration when the dose was increased from 10 to 40 mg/day."	( Yamamoto, A; Yamamura, T; Yokoyama, S, 1988)
"Nine heterozygous patients with familial hypercholesterolemia (FH) were treated by low density lipoprotein (LDL)-apheresis using dextran sulfate cellulose columns."	( Fujita, H; Kajinami, K; Koizumi, J; Mabuchi, H; Michishita, I; Takeda, M; Takeda, R; Takegoshi, T; Ueda, K; Wakasugi, T, 1988)
"Seven patients with familial hypercholesterolemia were treated fortnightly for 3 months by selective low-density lipoprotein apheresis with dextran-sulfate cellulose column (DSC)."	( Brando, B; Busnach, G; Cappelleri, A; Dal Col, A; Franceschini, G; Minetti, L; Perrino, ML; Sirtori, C; Vaccarino, V, 1988)
"The method of treatment of familial hypercholesterolemia did not affect the number of new cerebrovascular events."	( Kaste, M; Koivisto, P, 1988)
"Two homozygous patients with familial hypercholesterolemia were treated by double-filtration plasmapheresis."	( Mabuchi, H; Michishita, I; Sakai, T; Sakai, Y; Takeda, R; Wakasugi, T; Watanabe, A, 1986)
"Seventeen patients with familial hypercholesterolemia (9 males and 8 females) were treated with 1000 mg deoxycholic acid or placebo daily during 2 weeks in a double-blind, randomised cross-over fashion."	( Havekes, L; Kempen, HJ; Leuven, JA, 1986)
"Nine patients with familial hypercholesterolemia (FH), 6 with homozygotes and 3 with heterozygotes, were treated with long term repetitive LDL-apheresis."	( Hayashi, R; Satani, M; Yamamoto, A; Yokoyama, S, 1987)
"Fifty-one patients with familial hypercholesterolemia were treated for 2 to 4 years with probucol, cholestyramine, clofibrate and compactin in various combinations."	( Funahashi, T; Kishino, B; Matsuzawa, Y; Yamamoto, A; Yamamura, T; Yokoyama, S, 1986)
"For the treatment of familial hypercholesterolemia, Liposorber LA-40 was clinically applied."	( Kobayashi, H; Murotani, N; Nishide, T; Odaka, M; Saito, Y; Soeda, K; Takata, S; Tani, N; Yoshida, S, 1986)
"Patients with homozygous familial hypercholesterolemia (FH), reveal a marked heterogeneity in plasma cholesterol levels, response to diet as well as drug treatment, and clinical course."	( Brewer, HB; Gregg, RE; Hoeg, JM; Lakatos, E; Schaefer, EJ; Sprecher, DL; Zech, LA, 1985)
"Neomycin treatment in patients with type II hyperlipoproteinemia is an inexpensive and effective means of lowering the concentration of low-density lipoproteins and is free of significant side effects over a 3-mo period."	( Bailey, KR; Bou, E; Gregg, RE; Hoeg, JM; Pikus, AM; Romano, CA; Schaefer, EJ; Sprecher, DL; Wilson, PW; Zech, LA, 1984)
"Twelve patients with severe heterozygous familial hypercholesterolemia, in whom other hypolipidemic drug therapy had failed to reduce serum cholesterol levels to less than 300 mg/dL, were sequentially treated with mevinolin (a specific inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis) and colestipol."	( Illingworth, DR, 1984)
"Twenty two patients with primary type II hyperlipoproteinemia (13 phenotype IIa and 9 phenotype IIb) were treated with fenofibrate 300 mg a day for 4-12 months."	( Bonfiglioli, D; Cabrini, E; Fasoli, A; Pogliaghi, I; Sommariva, D, 1984)
"Homozygous familial hypercholesterolemia is refractory to standard dietary or drug therapy."	( Burr, IM; Greene, HL; Slonim, AE; Stacpoole, PW; Swift, LL; Younger, RK, 1982)
"One patient with familial hypercholesterolemia (untreated total cholesterol 800 mg%) received a combined drug treatment during 5 years."	( Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG, 1980)
"The patient was treated for a familial hyperlipoproteinemia type IIa."	( Achten, E; Algoed, L; Caemaert, J; de Reuck, J; van Aken, J, 1994)
"A 66-year-old male heterozygous familial hypercholesterolemia (FH) patient with significant coronary atherosclerosis has been treated by us with probucol (1000 mg daily) for eight years."	( Kajinami, K; Koizumi, J; Mabuchi, H; Nishitsuji, M; Shimizu, M; Takeda, Y, 1996)
"In patients with familial hypercholesterolemia, monotherapy with hydroxymethylglutaril coenzyme."	( Balestrieri, GP; Di Stefano, O; Maffi, V; Salvi, A; Scalvini, T; Sleiman, I; Spandrio, S, 1996)
"Patients with familial hypercholesterolemia (FH) (n = 53) were examined with B-mode ultrasound before and after 3 years of cholesterol-lowering therapy with pravastatin, cholestyramine, or a combination."	( Wendelhag, I; Wiklund, O; Wikstrand, J, 1995)
"Fourteen patients with familial hypercholesterolemia treated with lovastatin (40 mg/day) for three months were studied to find out whether the expected changes in plasma lipids are accompanied by modifications in the lipid composition of the erythrocyte membrane and whether these in turn induce changes in the rheological behavior of the red blood cell."	( Aznar, J; Carmena, R; Gil, L; Lluch, I; Martí, R; Martínez, M; Vayá, A, 1996)
"Eighteen patients with familial hypercholesterolemia treated with lovastatin (40 mg/day) for three months were studied to find out whether the drug induces modifications in the lipid composition of the erythrocyte membrane and whether these induce changes in the rheological behaviour of the red blood cell."	( Aznar, J; Carmena, R; Gil, L; Lluch, I; Marti, R; Martinez, M; Vaya, A, 1996)
"In total, 30 patients suffering from familial hypercholesterolemia, resistant to diet and lipid-lowering drugs, were treated for up to 6 years (3."	( Bambauer, R; Klinkmann, J; Latza, R; Schiel, R, 1996)
"In children with familial hypercholesterolemia, heterozygosity and homozygosity for the C677T mutation in the methylenetetrahydrofolate reductase gene was associated with low serum folate and increased susceptibility to elevation of plasma total homocysteine during cholestyramine treatment."	( Ose, L; Refsum, H; Tonstad, S; Ueland, PM, 1998)
"Patients with heterozygous familial hypercholesterolemia are at especially high risk of premature coronary artery disease and usually require aggressive long-term lipid-lowering drug therapy to decrease plasma low-density lipoprotein (LDL) cholesterol concentrations to normal levels."	( Kajinami, K; Koizumi, J; Mabuchi, H, 1998)
"Two girls with familial hypercholesterolemia were treated for 7 years by plasma exchanges (PE) or LDL-apheresis (LA)."	( Carla, H; Jouanel, P; Malpuech, G; Meyer, M; Palcoux, JB; Tridon, A; Vanlieferinghen, P, 1993)
"We treated 10 patients with familial hypercholesterolemia (FH) with HMG-CoA reductase inhibitors, and 13 patients with endogenous hypertriglyceridemia (HTG) with fibrates."	( de Man, FH; Mohrschladt, MF; Smelt, AH; Stoeken, DJ; Sturk, A; Westendorp, RG; Weverling-Rijnsburger, AW, 2000)
"A 50-year old male patient with familial hypercholesterolemia and hyperlipoproteinemia (a), who underwent low density lipoprotein-apheresis treatment developed heparin-induced thrombocytopenia type II (HIT II)."	( Kassner, U; Schliesser, C; Steinhagen-Thiessen, E; Thomas, HP, 2000)
"Patients with homozygous familial hypercholesterolemia (HoFH) have a high incidence of cardiovascular morbidity and mortality from premature atherosclerosis, and the efficacy of pharmacological therapy has been limited."	( Bruckert, E; Gagné, C; Gaudet, D, 2002)
"Liposorber is used to treat familial hypercholesterolemia (FH), peripheral arterial disease (PAD), and focal segmental glomerulosclerosis (FGS): Selesorb is used to treat systemic lupus erythematosus (SLE)."	( Asahi, T; Kutsuki, H; Yamamoto, T, 2003)
"Gene therapy of familial hypercholesterolemia (FH) requires successful transfer and lifelong expression of a functional low density lipoprotein receptor (LDLr) gene in the liver."	( Benhidjeb, T; Cichon, G; Heeren, J; Herwig, S; Löser, P; Niedzielska, D; Schlag, PM; Schmidt, HH; Schnieders, F; Uckert, W; Willnow, T, 2004)
"Two boys, aged 9 and 15 years, with familial hypercholesterolemia, who were highly resistant to dietary regimes and to drug therapy, were treated with the low density lipoprotein adsorber DALI apheresis once every 2 weeks for 24 weeks."	( Akgul, E; Bakkaloglu, A; Bayrakci, US; Besbas, N; Coskun, T; Kutluk, T; Ozcebe, O, 2005)
"Patients with homozygous familial hypercholesterolemia have markedly elevated cholesterol levels, which respond poorly to drug therapy, and a very high risk of premature cardiovascular disease."	( Bloedon, LT; Cuchel, M; Gregg, RE; Ikewaki, K; Kolansky, DM; Millar, JS; Rader, DJ; Sarkis, A; Siegelman, ES; Szapary, PO; Wolfe, ML, 2007)
"A 68-year-old man with familial hypercholesterolemia developed effort angina and received a sirolimus-eluting stent (SES) to treat 99% stenosis in segment 6 of the left anterior descending coronary artery in January 2005."	( Katayama, T; Ogata, N; Tsuruya, Y, 2007)
"In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant difference in changes in intima-media thickness, as compared with simvastatin alone, despite decreases in levels of LDL cholesterol and C-reactive protein."	( Akdim, F; Bots, ML; de Groot, E; Duivenvoorden, R; Gaudet, D; Kastelein, JJ; Marais, AD; Sijbrands, EJ; Stalenhoef, AF; Stein, EA; Stroes, ES; Trip, MD; Veltri, EP; Visseren, FL; Zwinderman, AH, 2008)
"LDL-apheresis is a treatment for familial hypercholesterolemia in addition to diet and drug therapy."	( Groisne, L; Hequet, O; Jaeger, S; Le, QH; Mekhloufi, F; Moulin, P; Rigal, D; Sassolas, A, 2010)
"Three patients with familial hypercholesterolemia participated in six consecutive treatments with three different LDL apheresis columns in random order: DL-75, LA-15, and EC-50W."	( Hardersen, R; Hovland, A; Lappegård, KT; Mollnes, TE; Nielsen, EW, 2010)
"To examine a case of heterozygous familial hypercholesterolemia (HeFH) in a primary care setting and to review the epidemiology, pathophysiology, etiology, and treatment guidelines to reduce the mortality related to this disease process."	( Friedrich, DA, 2010)
"Early identification of children with familial hypercholesterolemia (FH) makes it possible to start lipid-lowering therapy at a young age in order to prevent cardiovascular disease."	( Bruckert, E; Carreau, V; Girardet, JP, 2011)
"People with Familial Hypercholesterolemia (FH) may benefit from lifestyle changes supporting their primary treatment of dyslipidaemia."	( Broekhuizen, K; Brug, J; Kindt, I; Koppes, LL; van Mechelen, W; van Poppel, MN, 2012)
"LDL-apheresis is a treatment option for familial hypercholesterolemia (FH) with country-specific thresholds for LDL-cholesterol (LDL-C) for initiation."	( Parhofer, KG; Vogt, A, 2013)
"In children and adolescents with familial hypercholesterolemia (FH) pharmacotherapy with statins is the cornerstone in the current regimen to reduce low-density lipoprotein cholesterol (LDLc) and premature coronary heart disease risk."	( Drogari, E; Elens, L; Manolopoulos, VG; Mollaki, V; Ragia, G; Van Schaik, RH, 2014)
"Homozygous familial hypercholesterolemia (HoFH) is a very rare condition (1 case per 1 million people) with a dismal outcome due to inevitable coronary artery disease that occurs when left untreated."	( Shu, KH; Tsai, JL; Tsai, SF; Wu, MJ, 2016)
"The SAFEHEART study (Spanish Familial Hypercholesterolemia Cohort Study) is a large, ongoing registry of molecularly defined patients with heterozygous FH treated in Spain."	( Alonso, R; Badimón, L; Barba-Romero, MA; de Andrés, R; Diaz-Diaz, JL; Fuentes, F; Martinez-Faedo, C; Mata, N; Mata, P; Miramontes-Gonzalez, JP; Muñiz, O; Perez de Isla, L; Rubio-Marin, P; Saenz, P; Saltijeral Cerezo, A; Sanchez Muñoz-Torrero, JF; Watts, GF; Zambón, D, 2016)
"Patients with familial hypercholesterolemia (FH) may be at increased risk for statin-associated muscle symptoms because they require long-term treatment with high-intensity statin therapy."	( Adams-Huet, B; Ahmad, Z; Khine, H; Yuet, WC, 2016)
"Background Familial hypercholesterolemia is a common autosomal dominant disease, caused by mutations leading to elevated low-density lipoprotein (LDL) cholesterol and, if untreated, to premature cardiovascular disease."	( De Simone, B; Di Taranto, MD; Fortunato, G; Gentile, M; Giacobbe, C; Iannuzzi, A; Iannuzzo, G; Jossa, F; Marotta, G; Rubba, P; Sodano, M, 2017)
"Despite the high prevalence of familial hypercholesterolemia (FH) and available effective lipid-lowering therapy, most of the individuals with this disorder remain undiagnosed and undertreated."	( Blaha, V; Freiberger, T; Kyselak, O; Maskova, J; Raslová, K; Satny, M; Soska, V; Urbanek, R; Vaclova, M; Vohnout, B; Vrablik, M, 2018)
"Diagnosis and Treatment of Familial Hypercholesterolemia Abstract."	( Bärlocher, A; Bilz, S; Brändle, M; Gerth, Y; Korte, W; Müller, P; Rickli, H; Schöb, M, 2018)
"Background Familial hypercholesterolemia ( FH ), is a historically underdiagnosed, undertreated, high-risk condition that is associated with a high burden of cardiovascular morbidity and mortality."	( Carey, D; deRichemond, C; Geng, Z; Hu, Y; Jones, LK; Khan, A; Kirchner, HL; Kolinovsky, A; Krishnamurthy, S; Mehra, VC; Metpally, R; Patel, P; Ruhl, J; Snyder, S; Sturm, AC; Williams, MS, 2019)
"Regarding patients with familial hypercholesterolemia, those treated with probucol, which is a potent anti-oxidative and anti-hyperlipidemic drug, showed significantly lower Ox-HDL (16."	( Inui, H; Kanno, K; Katayama, Y; Koseki, M; Masuda, D; Nishida, M; Ohama, T; Okada, T; Saga, A; Sakata, Y; Sumida, M; Yamashita, S, 2021)
"The investigation of familial hypercholesterolemia (FH) and its relationship to atherosclerosis has led to enormous scientific and medical progress, including the identification of genetic defects underlying FH, the elucidation of molecular mechanisms crucial for cellular cholesterol homeostasis and the development of current pharmaceutical tools for FH treatment (which are directed at increasing LDL uptake)."	( Teixeira da Costa, LF, 2021)
"Individuals with familial hypercholesterolemia (FH) undergo an aggressive treatment with cholesterol-lowering drugs to prevent coronary heart disease."	( Hande, LN; Hansen, SH; Hov, JR; Hovland, A; Kummen, M; Lappegård, KT; Storm-Larsen, C; Thunhaug, H; Trøseid, M; Vestad, B, 2022)
"Normalization of LDL cholesterol in familial hypercholesterolemia (FH) is not an easy task and frequently requires specific treatment, such as regularly performed lipid apheresis and/or novel drugs such as proprotein convertase subtilisin kexin 9 monoclonal antibodies (PCSK9Ab)."	( Bláha, M; Blaha, V; Carazo, A; Hrubša, M; Javorská, L; Karlíčková, J; Konečný, L; Krčmová, LK; Matoušová, K; Mladěnka, P; Šmahelová, A, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	955 (33.69)	23.3326
1990's	766 (27.02)	12.5806
2000's	511 (18.02)	18.1394
2010's	466 (16.44)	28.8240
2020's	137 (4.83)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	low	1	0
gamma-aminobutyric acid	low	1	0
acetic acid	low	4	0
adenine	low	2	0
ammonium hydroxide	low	2	0
1-butanol	medium	1	1
carbamates	low	1	0
carnitine	low	3	0
choline	low	2	0
citric acid, anhydrous	low	2	0
chlorine	low	1	0
gallic acid	low	1	0
n(g),n(g')-dimethyl-l-arginine	medium	4	1
aminocaproic acid	low	1	0
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
glycine	low	3	0
glycerol	low	2	0
dalteparin	low	1	0
iodine	low	3	0
thioctic acid	low	1	0
inositol	low	3	0
niacin	medium	51	11
nitrates	low	2	0
nitrites	low	2	0
oxalic acid	low	1	0
1-propanol	medium	12	11
propionic acid	low	1	0
pyridoxal phosphate	medium	1	1
pyridoxine	low	1	0
toluene	low	1	0
uracil	low	1	0
uric acid	medium	9	2
urea	low	1	0
1-anilino-8-naphthalenesulfonate	medium	23	2
phenytoin	low	1	0
tacrine	medium	1	1
acetazolamide	low	1	0
theophylline	medium	2	1
amlodipine	low	2	0
acetovanillone	low	1	0
aspirin	medium	6	2
benzamidine	medium	1	1
bethanechol	low	1	0
buformin	low	1	0
verapamil	low	3	0
chloroquine	low	2	0
cimetidine	low	1	0
ciprofibrate	medium	11	9
clinofibrate	low	1	0
clofibrate	medium	73	15
clofibric acid	medium	42	15
cyclandelate	medium	1	1
dipyridamole	low	6	0
donepezil	low	1	0
doxazosin	low	1	0
erythrosine	low	1	0
eicosapentaenoic acid ethyl ester	low	1	0
felbamate	low	1	0
felodipine	medium	1	1
fenofibrate	medium	72	25
furosemide	low	1	0
gabapentin	low	1	0
gemfibrozil	medium	46	17
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	low	1	0
hydralazine	low	1	0
indomethacin	low	1	0
inositol niacinate	low	2	0
iohexol	low	3	0
iopromide	low	2	0
avapro	low	2	0
2-propanol	low	1	0
ketoconazole	low	5	0
lamotrigine	low	1	0
losartan	low	2	0
meclofenamic acid	low	1	0
nafamostat	low	1	0
niceritrol	low	3	0
nifedipine	low	1	0
nitroglycerin	medium	8	2
ofloxacin	low	1	0
perhexiline	low	1	0
pifithrin	low	1	0
potassium chloride	low	1	0
prazosin	low	1	0
probucol	medium	94	17
pyridinolcarbamate	low	1	0
sulfinpyrazone	low	1	0
suramin	low	1	0
theobromine	low	1	0
ticlopidine	low	2	0
troglitazone	low	1	0
tyramine	low	1	0
hydrocortisone acetate	low	1	0
corticosterone	low	1	0
prednisolone	low	1	0
estriol	medium	1	1
sorbitol	low	2	0
thymidine	low	2	0
hydroxyproline	low	1	0
thyroxine	medium	13	2
carbachol	low	1	0
aldosterone	low	2	0
tetrahydrocortisol	low	1	0
tetrahydrocortisone	low	1	0
oxandrolone	low	1	0
dehydroepiandrosterone	medium	2	1
triiodothyronine	low	8	0
biguanides	low	1	0
serine	low	1	0
aspartic acid	low	2	0
glutamine	medium	5	2
lysine	low	6	0
sucrose	low	1	0
ethinyl estradiol	low	3	0
adenosine diphosphate	medium	19	3
galactose	low	2	0
phenylephrine	low	1	0
edetic acid	low	4	0
phenylethyl alcohol	low	1	0
tyrosine	low	3	0
methylene blue	low	1	0
leucine	low	14	0
methionine	low	7	0
phenylalanine	low	2	0
cycloheximide	low	3	0
histidine	low	1	0
valine	low	5	0
threonine	low	2	0
tryptophan	low	6	0
isoleucine	low	2	0
arginine	medium	22	4
triparanol	low	4	0
acrylic acid	low	1	0
isosorbide dinitrate	low	2	0
butyl methacrylate	low	1	0
nicotinyl alcohol	medium	9	1
epichlorohydrin	medium	4	3
allylamine	medium	5	3
pyrroles	medium	116	54
framycetin	medium	20	7
dextrothyroxine	medium	7	1
pregnenolone	low	3	0
quinazolines	low	1	0
oxazoles	medium	1	1
thiazoles	low	2	0
pyrazines	medium	7	5
citrulline	low	2	0
xanthinol niacinate	medium	4	1
4-methylcatechol	low	1	0
fluorobenzenes	medium	25	8
limestone	medium	1	1
chenodeoxycholic acid	medium	5	2
cyanogen bromide	low	1	0
malondialdehyde	medium	21	4
dehydroepiandrosterone sulfate	low	1	0
ethylnitrosourea	low	2	0
1,2-cyclohexanedione	low	2	0
d-alpha tocopherol	medium	30	6
tocopherols	low	2	0
selenomethionine	low	1	0
nitrofen	low	1	0
uridine diphosphate galactose	low	1	0
fluorescein-5-isothiocyanate	medium	3	1
dithiothreitol	low	1	0
megestrol	low	1	0
tiadenol	medium	3	1
manganese	low	2	0
technetium	low	3	0
acetylglucosamine	low	1	0
hypochlorous acid	low	1	0
copper sulfate	low	1	0
deuterium	low	2	0
ozone	low	1	0
trolamine salicylate	low	13	0
tiletamine hydrochloride	low	5	0
cromolyn sodium	low	1	0
tetradecanoylphorbol acetate	low	3	0
tocopheryl nicotinate	low	1	0
fluorides	low	1	0
phenyl acetate	medium	11	1
transferrin	medium	6	1
glutamic acid	low	6	0
sodium azide	low	1	0
azides	low	1	0
halofenate	low	1	0
paclitaxel	low	6	0
bezafibrate	medium	68	35
etofylline clofibrate	medium	6	2
captopril	medium	3	1
colforsin	low	1	0
beclobrate	medium	2	2
fomesafen	low	1	0
acifran	medium	2	2
lovastatin	medium	243	71
simvastatin	medium	230	91
pravastatin	medium	103	34
lifibrol	medium	1	1
atorvastatin	medium	130	54
adenosine	low	2	0
colestipol	medium	76	19
trazodone hydrochloride	medium	1	1
glucose, (beta-d)-isomer	low	1	0
mevastatin	medium	18	1
fenofibric acid	medium	18	8
cholesteryl sulfate	low	3	0
25-hydroxycholesterol	low	1	0
glutathione disulfide	medium	2	1
etiroxate	medium	4	2
lathosterol	medium	22	6
etofibrate	medium	12	3
mci-196	medium	5	4
iobitridol	low	1	0
1-octacosanol	medium	1	1
fluorodeoxyglucose f18	low	2	0
pirozadil	low	2	0
rilmenidine	medium	1	1
plafibride	low	2	0
pirinixil	medium	1	1
2-(aminomethyl)phenol	low	2	0
pentifylline	low	1	0
tyloxapol	low	1	0
leupeptin	low	1	0
oxazolidin-2-one	medium	5	2
4-aminopyrazolo(3,4-d)pyrimidine	low	1	0
fibrinogen	medium	59	20
7-ketocholesterol	low	3	0
homocysteine	medium	17	6
nomegestrol acetate	low	1	0
zofenopril	low	1	0
gamma-tocopherol	low	1	0
zymostenol	low	1	0
yttrium radioisotopes	low	1	0
chlorates	low	1	0
vitamin b 6	medium	1	1
pregnenolone sulfate	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	5	0
valerates	medium	11	7
thromboxanes	medium	6	2
7 alpha-hydroxy-4-cholesten-3-one	medium	2	2
n,n-dimethylarginine	medium	4	1
hoe 694	low	1	0
27-hydroxycholesterol	low	1	0
glycerophosphoinositol 4,5-bisphosphate	low	1	0
ci 924	medium	1	1
olmesartan medoxomil	low	1	0
mdl 29311	low	1	0
omega-n-methylarginine	medium	2	1
proline	low	4	0
levofloxacin	low	1	0
ezetimibe	medium	135	22
gemcabene	medium	2	1
torcetrapib	medium	6	5
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol	low	1	0
avasimibe	medium	1	1
biotin	low	1	0
angiotensin ii	medium	9	1
campesterol	medium	11	3
magnesium-pyridoxal-5'-phosphate glutamate	medium	1	1
lignin	medium	1	1
psyllium	low	1	0
cholic acid	low	1	0
deoxycholic acid	medium	1	1
cortisone	low	2	0
3-nitrotyrosine	low	1	0
stigmastanol	medium	3	1
lanosterol	medium	4	1
trimethoprim, sulfamethoxazole drug combination	low	1	0
leupeptins	low	1	0
mannose-6-phosphate	low	1	0
fibrin	low	4	0
bradykinin	low	8	0
elastin	low	3	0
mevalonic acid	medium	29	10
pantetheine	medium	5	2
inositol 1,4,5-trisphosphate	low	1	0
desmosterol	medium	7	1
monensin	low	1	0
ergonovine	low	2	0
betadex	low	1	0
arachidonic acid	medium	11	1
3-hydroxy-3-methylglutaryl-coenzyme a	medium	3	1
retinol	medium	16	2
oleic acid	low	5	0
pectins	low	1	0
cerivastatin	low	2	0
eicosapentaenoic acid	medium	14	8
lycopene	low	1	0
t0901317	low	1	0
adenosine-5'-(n-ethylcarboxamide)	low	1	0
prostaglandin d2	low	2	0
diethylstilbestrol	low	1	0
pantethine	medium	5	2
dactinomycin	low	1	0
gamma-sitosterol	medium	22	5
sodium chlorate	low	1	0
cholestane-3,5,6-triol	low	1	0
isomethyleugenol	low	2	0
squalene	medium	8	1
phenylthiourea	low	1	0
sodium propionate	low	1	0
thioacetamide	medium	1	1
tamoxifen	low	2	0
nadp	low	1	0
lithium	low	2	0
orlistat	low	2	0
beta-cyclodextrin tetradecasulfate	low	1	0
beta-sitosterol sulfate	low	1	0
methenolone	low	1	0
glucitol hexanicotinate	low	2	0
safingol	low	1	0
pactimibe	medium	2	1
cytellin	medium	39	10
sodium dodecyl sulfate	low	1	0
alpha-chymotrypsin	low	1	0
alpha-carotene	low	1	0
osteoprotegerin	low	1	0
cathepsin g	low	1	0
sphingosine	low	4	0
quercetin	low	1	0
ubiquinone q2	low	1	0
bilirubin	medium	5	1
dinoprostone	low	2	0
dinoprost	medium	11	1
linoleic acid	medium	6	1
calcitriol	low	1	0
beta carotene	low	4	0
leukotriene b4	low	2	0
thromboxane a2	low	5	0
retinol palmitate	low	3	0
8,11,14-eicosatrienoic acid	low	1	0
alprostadil	medium	4	1
stigmasterol	low	1	0
cholecalciferol	low	1	0
6-ketoprostaglandin f1 alpha	low	1	0
11-dehydro-thromboxane b2	medium	3	2
zeaxanthin	low	1	0
gamma-linolenic acid	medium	2	1
alpha-linolenic acid	low	1	0
amphotericin b	low	1	0
mivacurium	low	1	0
astaxanthine	low	1	0
canthaxanthin	low	1	0
cryptoxanthins	low	1	0
daidzein	medium	1	1
caffeic acid phenethyl ester	low	1	0
coenzyme q10	medium	9	2
8-epi-prostaglandin f2alpha	low	8	0
isotretinoin	low	1	0
pitavastatin	medium	8	6
thromboxane b2	medium	20	4
2,3-dinor-thromboxane b2	low	1	0
4-hydroxy-2-nonenal	low	1	0
sphingosine 1-phosphate	low	5	0
cholesteryl oleate	low	3	0
sirolimus	low	4	0
cerium	low	1	0
acipimox	medium	6	5
iloprost	low	3	0
lysophosphatidylcholines	low	6	0
12-hydroxy-5,8,10,14-eicosatetraenoic acid	low	2	0
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid	low	1	0
aluminum	medium	1	1
thallium	low	1	0
ridogrel	low	1	0
sulfur	low	1	0
diphenylhexatriene	low	1	0
cysteine	low	9	0
triolein	low	1	0
docosapentaenoic acid	medium	1	1
3,3'-dioctadecylindocarbocyanine	medium	4	1
carbocyanines	medium	5	1
selenium	low	3	0
oxalates	low	1	0
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid	medium	28	20
mevalonolactone	low	1	0
cholestanol	medium	4	1
dolichols	low	1	0
thermozymocidin	low	2	0
cholesteryl oleyl ether	low	1	0
everolimus	low	2	0
cdw17 antigen	low	1	0
i(3)so3-galactosylceramide	low	1	0
glucuronyl glucosamine glycan sulfate	medium	5	2
beta-escin	low	1	0
6 beta-hydroxycortisol	low	2	0
gadolinium dtpa	low	1	0
dalcetrapib	medium	2	1
omacor	medium	1	1
ezetimibe, simvastatin drug combination	medium	7	2
bms201038	medium	71	11
gc 1 compound	low	1	0
mocetinostat	medium	3	1
ticagrelor	low	1	0
tak 475	low	1	0
zotarolimus	low	1	0
sch 60663	low	1	0
cystathionine	medium	1	1
dimethylarginine	medium	1	1
kb 2115	medium	2	1
etc-1002	medium	10	1
anacetrapib	medium	4	2
calcimycin	low	2	0
sepharose	low	9	0
methylamphotericin b	low	1	0
phytosterols	medium	46	12
icatibant	low	1	0
nad	low	1	0
mgl-3196	low	1	0
cosyntropin	low	2	0
atrial natriuretic factor	low	4	0
glucagon	low	6	0
angiotensinogen	low	3	0
oligonucleotides	medium	58	12
c-peptide	low	1	0
cellulose	medium	35	3
endothelin-1	low	4	0
phosphatidylcholines	medium	16	2
ubiquinone	medium	13	2
technetium tc 99m sestamibi	low	2	0
s-adenosylmethionine	low	1	0
cardiovascular agents	medium	9	1
mannans	medium	9	4
glycolipids	medium	7	2
piperidines	low	3	0
interleukin-8	low	3	0
sofosbuvir	low	1	0
evacetrapib	low	1	0
4-methylcholest-7-en-3-ol	low	2	0
natriuretic peptide, brain	low	2	0
heparitin sulfate	low	1	0
ascorbic acid	medium	9	2
vericiguat	low	1	0
warfarin	medium	1	1
epidermal growth factor	low	11	0
d-4f peptide	low	1	0
transforming growth factor beta	low	1	0
globotriaosylceramide	low	1	0
rome	low	2	0
hirudin	low	1	0
caseins	low	1	0
angiotensin i	low	1	0
vitamin b 12	medium	3	2
oblimersen	low	1	0
cyclosporine	low	2	0
cytochalasin d	low	1	0
lactoferrin	low	1	0
apyrase	low	1	0
thromboplastin	low	2	0
promega	medium	2	2
exudates	low	10	0
cyclic gmp	low	3	0
deoxyguanosine	low	1	0
guanine	low	1	0
hypoxanthine	medium	1	1
sapropterin	low	1	0
folic acid	medium	8	5
neopterin	low	2	0
rifampin	low	1	0
ganciclovir	low	1	0
allopurinol	medium	4	1
xanthopterin	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
5-methyltetrahydrofolate	medium	1	1
cholestyramine resin	medium	146	46
eye	low	6	0
concanavalin a	low	2	0
phosphorus radioisotopes	low	1	0
4-hydroxyatorvastatin	medium	1	1
leptin	low	2	0
filipin	low	1	0

Protein Targets (2,397)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Cytochrome P450 2C9	0	21	2	24
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	53	0	0	53
thioredoxin reductase	45	0	0	45
ATAD5 protein, partial	30	0	0	30
GLS protein	28	0	0	28
TDP1 protein	96	0	0	96
regulator of G-protein signaling 4	38	0	0	38
67.9K protein	20	0	0	20
Parkin	14	0	0	14
bromodomain adjacent to zinc finger domain 2B	16	0	0	16
IDH1	28	0	0	28
euchromatic histone-lysine N-methyltransferase 2	87	0	0	87
nuclear factor erythroid 2-related factor 2 isoform 2	22	0	0	23
huntingtin isoform 2	6	0	0	6
ras-related protein Rab-9A	10	0	0	10
serine/threonine-protein kinase mTOR isoform 1	14	0	0	14
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
survival motor neuron protein isoform d	29	0	0	29
D(1A) dopamine receptor	7	1	0	8
Ataxin-2	23	0	0	23
ATP-dependent phosphofructokinase	29	0	0	29
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	16	0	0	16
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	8	0	0	8
USP1 protein, partial	55	0	0	55
vitamin D3 receptor isoform VDRA	40	0	0	40
importin subunit beta-1 isoform 1	10	0	0	10
flap endonuclease 1	19	0	0	19
serine/threonine-protein kinase PLK1	12	0	0	12
snurportin-1	10	0	0	10
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	14	0	0	14
GTP-binding nuclear protein Ran isoform 1	6	0	0	6
DNA polymerase eta isoform 1	9	0	0	9
DNA polymerase iota isoform a (long)	23	0	0	23
geminin	78	0	0	78
DNA polymerase kappa isoform 1	29	0	0	29
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	3	0	3
Transthyretin	0	3	4	9
Fatty acid-binding protein, intestinal	0	6	2	8
Fatty acid-binding protein, adipocyte	0	6	2	8
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	2	1	3
Cyclin-dependent kinase 2	0	2	3	5
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	12	0	0	12
Fatty acid-binding protein 5	0	3	1	4
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	2	3
Mitogen-activated protein kinase 14	0	4	3	7
aldehyde dehydrogenase 1 family, member A1	68	0	0	68
glucocorticoid receptor [Homo sapiens]	81	0	0	81
farnesoid X nuclear receptor	48	0	0	48
estrogen nuclear receptor alpha	123	0	0	123
Voltage-dependent calcium channel gamma-2 subunit	38	0	0	38
Cellular tumor antigen p53	63	0	0	63
Glutamate receptor 2	39	2	1	42
Choline O-acetyltransferase	0	5	0	7
Chain A, Cruzipain	23	0	0	23
Platelet-activating factor receptor	0	2	0	3
Inositol monophosphatase 1	14	0	0	14
Cocaine esterase	0	1	0	1
Cholinesterase	0	6	0	6
Liver carboxylesterase 1	0	1	0	1
Acetylcholinesterase	0	11	2	13
Liver carboxylesterase 1	0	4	0	4
hypoxia-inducible factor 1 alpha subunit	24	0	0	24
RAR-related orphan receptor gamma	63	0	0	63
GLI family zinc finger 3	67	0	0	67
AR protein	107	0	0	107
retinoic acid nuclear receptor alpha variant 1	72	0	0	72
retinoid X nuclear receptor alpha	57	0	0	57
peroxisome proliferator-activated receptor delta	43	0	0	43
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	40	0	0	40
activating transcription factor 6	34	0	0	34
v-jun sarcoma virus 17 oncogene homolog (avian)	36	0	0	36
Histone H2A.x	23	0	0	23
thyroid hormone receptor beta isoform a	36	0	0	36
heat shock protein beta-1	32	0	0	32
nuclear factor erythroid 2-related factor 2 isoform 1	71	0	0	71
lamin isoform A-delta10	67	0	0	67
cytochrome P450 family 3 subfamily A polypeptide 4	59	0	0	59
peripheral myelin protein 22	43	0	0	43
Alpha-crystallin B chain	0	0	2	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	9	1	10
Integrin beta-3	11	3	2	16
Integrin alpha-V	0	1	1	2
Nuclear receptor ROR-gamma	18	2	3	23
Glutamate receptor ionotropic, NMDA 1	0	2	4	6
Sterol regulatory element-binding protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	5	7
Oxysterols receptor LXR-alpha	0	2	4	6
Glutamate receptor ionotropic, NMDA 2B	0	2	5	8
Oxysterol-binding protein 2	0	0	1	1
NPC1-like intracellular cholesterol transporter 1	0	2	3	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	20	0	0	20
phosphopantetheinyl transferase	40	0	0	40
pyruvate kinase PKM isoform a	2	0	0	2
Glycoprotein hormones alpha chain	2	0	0	2
Tubulin--tyrosine ligase	0	2	0	2
Phosphatidylinositol 4-kinase alpha	0	6	0	7
Xanthine dehydrogenase/oxidase	0	8	0	8
Leucine-rich repeat serine/threonine-protein kinase 2	0	4	0	4
Phosphatidylinositol 4-kinase type 2-beta	0	6	0	7
Phosphatidylinositol 4-kinase type 2-alpha	0	6	0	7
Phosphatidylinositol 4-kinase beta	0	6	0	7
Microtubule-associated protein tau	45	0	0	45
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Luciferase	36	0	0	36
acetylcholinesterase	26	0	0	26
estrogen receptor 2 (ER beta)	37	0	0	37
nuclear receptor subfamily 1, group I, member 3	40	0	0	40
progesterone receptor	43	0	0	43
estrogen-related nuclear receptor alpha	74	0	0	74
pregnane X nuclear receptor	58	0	0	58
vitamin D (1,25- dihydroxyvitamin D3) receptor	49	0	0	49
aryl hydrocarbon receptor	27	0	0	27
thyroid stimulating hormone receptor	29	0	0	29
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	27	0	0	27
thyroid hormone receptor beta isoform 2	59	0	0	59
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	16	0	0	16
Solute carrier organic anion transporter family member 2A1	0	3	0	10
Rap guanine nucleotide exchange factor 3	14	0	0	14
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Trypsin	0	8	0	9
Coagulation factor VII	0	8	0	8
Tissue factor	0	8	0	8
Oxoeicosanoid receptor 1	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	31	0	0	31
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	26	0	0	26
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
GALC protein	8	0	0	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	27	0	0	27
Carbonic anhydrase	0	1	0	1
Bloom syndrome protein isoform 1	31	0	0	31
muscleblind-like protein 1 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	35	6	1	42
ATP-binding cassette sub-family C member 3	0	46	0	46
Multidrug resistance-associated protein 4	0	47	0	52
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	6	1	15
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	73	0	73
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	4	0	4
Carbonic anhydrase 1	0	17	1	32
Carbonic anhydrase 2	0	19	2	35
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	8	0	9
Carbonic anhydrase 3	0	5	1	13
Cathepsin B	0	2	0	2
Cytochrome P450 3A4	0	22	2	28
Steryl-sulfatase	0	1	0	2
5-hydroxytryptamine receptor 2C	0	4	1	5
Polyunsaturated fatty acid 5-lipoxygenase	0	7	0	7
Cytochrome P450 2C8	0	7	0	7
Cytochrome P450 2D6	0	10	0	10
Cytochrome P450 2A6	0	1	0	1
5-hydroxytryptamine receptor 2A	0	7	1	8
Androgen receptor	0	13	0	13
Gamma-aminobutyric acid receptor subunit beta-1	35	6	1	42
Translocator protein	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	35	6	1	42
Gamma-aminobutyric acid receptor subunit gamma-2	35	6	2	43
Gamma-aminobutyric acid receptor subunit alpha-5	35	6	1	42
Gamma-aminobutyric acid receptor subunit alpha-3	35	6	1	42
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	5	1	6
Carbonic anhydrase 4	0	13	1	21
Carbonic anhydrase 6	0	5	1	13
Gamma-aminobutyric acid receptor subunit gamma-1	35	6	1	42
Gamma-aminobutyric acid receptor subunit alpha-2	35	6	1	42
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	12	3	20
Serum paraoxonase/arylesterase 1	0	4	0	4
Dipeptidyl peptidase 4	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	35	6	1	42
Gamma-aminobutyric acid receptor subunit gamma-3	35	6	1	42
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	35	6	1	42
Adenosine receptor A2a	0	12	2	21
5-hydroxytryptamine receptor 2B	0	3	1	4
Sodium-dependent serotonin transporter	0	3	1	4
Delta-type opioid receptor	0	4	0	5
Cytochrome P450 2C19	0	10	0	10
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	3
Carbonic anhydrase 5A, mitochondrial	0	7	1	16
Carbonic anhydrase	0	7	0	12
Kappa-type opioid receptor	0	3	1	4
Carbonic anhydrase 7	0	6	1	14
Carbonic anhydrase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	7
D(2) dopamine receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	35	7	2	44
Gamma-aminobutyric acid receptor subunit beta-3	35	6	1	42
Gamma-aminobutyric acid receptor subunit beta-2	35	6	2	43
Cholinesterase	0	6	0	6
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	2	1	3
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	6	3	14
Squalene synthase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	3	1	4
Carbonic anhydrase 9	0	8	2	18
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	1	0	8
Carbonic anhydrase	0	2	0	9
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	2	6
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	7
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	7
GABA theta subunit	35	6	1	42
Canalicular multispecific organic anion transporter 1	0	39	0	39
Carbonic anhydrase 4	0	2	0	5
Carbonic anhydrase 15	0	6	0	12
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	5	0	11
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	35	6	1	42
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	5	1	14
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	1	14
Free fatty acid receptor 3	0	0	2	2
Free fatty acid receptor 2	0	2	2	4
Tyrosine-protein kinase Lck	0	3	3	6
Tyrosine-protein kinase Fyn	0	5	3	8
Fibrinogen C domain-containing protein 1	0	1	0	1
chromobox protein homolog 1	41	0	0	41
Putative glycosyltransferase WbgO	0	0	0	1
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	1	2	3
Hydroxycarboxylic acid receptor 2	0	3	3	6
Fumarate hydratase	17	0	0	17
EWS/FLI fusion protein	42	0	0	42
polyprotein	17	0	0	17
histone acetyltransferase KAT2A isoform 1	34	0	0	34
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
tumor susceptibility gene 101 protein	2	0	0	2
Cyclin-dependent kinase 1	0	2	2	4
Heat shock protein HSP 90-beta	0	2	1	4
TAR DNA-binding protein 43	26	0	0	26
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
ATPase family AAA domain-containing protein 5	16	0	0	16
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	2	0	2
Chain A, ADENOSINE RECEPTOR A2A	0	2	0	2
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
NPYLR7B	0	0	2	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	21	0	0	21
nuclear receptor ROR-gamma isoform 1	36	0	0	36
high affinity choline transporter 1 isoform a	0	2	0	2
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	9	2	11
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	4	0	4
Insulin receptor	0	0	2	3
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	3	3	7
Platelet-derived growth factor receptor beta	0	0	2	3
Adenosine receptor A3	0	22	3	26
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	1	2	4
Inosine-5'-monophosphate dehydrogenase 2	0	1	2	3
Endoplasmin	0	2	2	5
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	2	2
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	12	6	21
Adenosine receptor A2b	0	2	2	7
Adenosine receptor A2b	0	5	2	9
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	16	5	26
Adenylate kinase isoenzyme 1	0	1	0	1
Adenosine receptor A1	0	2	2	4
Adenosine kinase	0	0	2	3
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	3	0	3
Mu-type opioid receptor	0	6	2	8
Delta-type opioid receptor	0	8	2	10
Kappa-type opioid receptor	0	6	2	8
Endoplasmin	0	1	2	3
P2Y purinoceptor 2	0	1	2	3
P2X purinoceptor 1	0	0	3	3
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	1	1	2
P2X purinoceptor 4	0	0	3	3
P2X purinoceptor 5	0	0	2	2
P2X purinoceptor 6	0	0	2	2
P2X purinoceptor 3	0	0	2	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	1	1	2
P2Y purinoceptor 11	0	1	2	3
P2Y purinoceptor 12	0	1	2	3
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	2	2
Chain A, Endoplasmin	0	0	1	1
glp-1 receptor, partial	18	0	0	18
vasopressin V1b receptor	1	0	0	1
D(1A) dopamine receptor	15	0	0	15
thyrotropin-releasing hormone receptor	1	0	0	1
relaxin receptor 1 isoform 1	3	0	0	3
relaxin receptor 2 isoform 1	2	0	0	2
Transmembrane domain-containing protein TMIGD3	0	1	0	1
Thyroid hormone receptor beta	0	4	0	4
Alpha-2B adrenergic receptor	0	6	1	7
Alpha-2C adrenergic receptor	0	6	1	7
Alpha-2A adrenergic receptor	0	6	1	7
Adenosine receptor A1	0	3	0	3
5-hydroxytryptamine receptor 2A	0	11	0	11
Alpha-1A adrenergic receptor	0	6	2	13
Alpha-synuclein	13	5	0	18
Aflatoxin B1 aldehyde reductase member 3	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenylate cyclase type 5	0	1	0	1
Endoplasmin	0	0	1	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A3	0	1	1	2
2-oxoglutarate receptor 1	0	1	0	1
Sex hormone-binding globulin	0	0	8	8
Corticosteroid-binding globulin	0	9	0	9
Mineralocorticoid receptor	0	3	4	7
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	4	0	8
interleukin 8	17	0	0	17
thyroid stimulating hormone receptor	34	0	0	34
transcriptional regulator ERG isoform 3	6	0	0	6
Polyphenol oxidase 2	0	6	0	9
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	3
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	1	7
Purine nucleoside phosphorylase	0	0	2	2
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	2	0	2
Amine oxidase [flavin-containing] B	0	4	0	4
Amine oxidase [flavin-containing] A	0	4	0	4
Chain A, HADH2 protein	32	0	0	32
Chain B, HADH2 protein	32	0	0	32
Chain A, 2-oxoglutarate Oxygenase	31	0	0	31
Chain A, ATP-DEPENDENT DNA HELICASE Q1	12	0	0	12
15-lipoxygenase, partial	17	0	0	17
WRN	2	0	0	2
SMAD family member 2	20	0	0	20
SMAD family member 3	20	0	0	20
thioredoxin glutathione reductase	15	0	0	15
peroxisome proliferator activated receptor gamma	54	0	0	54
Caspase-7	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	22	0	0	22
phospholipase A2 precursor	0	1	0	1
caspase-3	7	0	0	7
cysteine protease ATG4B isoform a	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	7	0	0	7
cytochrome P450 3A4 isoform 1	35	0	0	35
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
Free fatty acid receptor 1	0	0	3	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	14	2	0	16
Prostaglandin G/H synthase 1	0	8	0	10
Nuclear receptor subfamily 1 group I member 2	0	2	11	13
Aromatase	0	10	0	10
Prostaglandin G/H synthase 1	0	13	0	13
Peroxisome proliferator-activated receptor gamma	0	5	14	20
Histamine H2 receptor	22	2	2	26
Prostaglandin G/H synthase 2	0	7	0	8
Free fatty acid receptor 4	0	0	2	2
Thromboxane-A synthase	0	8	0	8
Prostaglandin E2 receptor EP3 subtype	0	3	0	3
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin E2 receptor EP1 subtype	0	3	0	3
Prostacyclin receptor	0	6	3	9
Nuclear receptor subfamily 4 group A member 2	0	0	7	7
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Solute carrier organic anion transporter family member 2A1	0	2	0	7
Solute carrier organic anion transporter family member 2B1	0	2	0	3
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, Ferritin light chain	29	0	0	29
Chain A, Apolipoprotein	0	0	1	1
nonstructural protein 1	8	0	0	8
Plasminogen	0	5	1	6
Proton-coupled amino acid transporter 1	0	8	0	9
Smad3	16	0	0	16
G	37	0	0	37
cytochrome P450 2D6	29	0	0	29
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Potassium channel subfamily K member 2	0	1	3	4
Interferon beta	47	0	0	47
HLA class I histocompatibility antigen, B alpha chain	37	0	0	37
ATP-dependent translocase ABCB1	0	21	3	37
Alpha-2A adrenergic receptor	0	20	4	25
Alpha-2C adrenergic receptor	0	12	3	16
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Alpha-1D adrenergic receptor	0	9	1	13
Alpha-1B adrenergic receptor	0	5	2	10
5-hydroxytryptamine receptor 6	0	8	0	8
Spike glycoprotein	30	1	5	36
Sodium-dependent dopamine transporter	0	16	0	16
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	9
Potassium channel subfamily K member 2	0	2	0	2
Inositol hexakisphosphate kinase 1	37	0	0	37
cytochrome P450 2C9, partial	37	0	0	37
tumor necrosis factor	2	0	0	2
Potassium voltage-gated channel subfamily H member 2	0	25	0	26
Aurora kinase B	0	2	3	5
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	12	2	15
Cholesteryl ester transfer protein	0	5	0	5
Chain A, retinol dehydratase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	6	0	6
G-protein coupled bile acid receptor 1	0	1	6	7
glucocerebrosidase	13	0	0	13
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	2	6
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	5	0	5
Type-1 angiotensin II receptor	0	6	3	12
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	4	0	4
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, SERUM ALBUMIN	0	0	2	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9	0	0	9
cellular tumor antigen p53 isoform a	13	0	0	13
ubiquitin carboxyl-terminal hydrolase 2 isoform a	9	0	0	9
caspase-1 isoform alpha precursor	4	0	0	4
Fatty-acid amide hydrolase 1	0	3	0	3
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Prostaglandin G/H synthase 2	0	16	2	19
10 kDa heat shock protein, mitochondrial	0	4	0	4
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	7	1	0	8
Thiosulfate sulfurtransferase	0	4	0	4
Lanosterol 14-alpha demethylase	0	7	1	9
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Solute carrier organic anion transporter family member 1B3	0	19	0	24
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	25	0	33
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	10	0	0	10
alpha-galactosidase	6	0	0	6
cytochrome P450 2C19 precursor	14	0	0	14
muscarinic acetylcholine receptor M1	19	0	0	19
lethal factor (plasmid)	21	0	0	21
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	4	1	6
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, inducible	0	4	0	5
Nitric oxide synthase, inducible	0	2	1	5
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	4
Alpha-2B adrenergic receptor	0	18	3	22
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	4
Glutamate receptor ionotropic, NMDA 1	0	6	3	14
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	5	3	13
Glutamate receptor ionotropic, NMDA 2C	0	5	3	13
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	8
Glutamate receptor ionotropic, NMDA 2D	0	5	3	13
Glutamate receptor ionotropic, NMDA 3B	0	5	3	13
Glutamate receptor ionotropic, NMDA 3A	0	5	3	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	6	0	0	6
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	5
Fatty acid-binding protein, liver	0	9	3	12
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	4	0	5
Seed linoleate 13S-lipoxygenase-1	0	4	0	6
Integrin alpha-IIb	11	2	1	14
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	1	3	4
caspase 7, apoptosis-related cysteine protease	12	0	0	12
caspase-3	12	0	0	12
Solute carrier organic anion transporter family member 2B1	0	6	0	8
Insulin receptor	0	6	0	6
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	7	0	7
Histone deacetylase 1	0	5	0	5
Histone deacetylase 2	0	5	0	5
Histone deacetylase 6	0	4	0	4
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
lysosomal alpha-glucosidase preproprotein	10	0	0	10
Neuronal acetylcholine receptor subunit alpha-4	5	4	0	9
Neuronal acetylcholine receptor subunit beta-2	5	4	0	9
Thromboxane A2 receptor	0	3	2	7
Endothelin-1 receptor	0	2	0	2
Sodium/bile acid cotransporter	0	5	0	5
Multidrug and toxin extrusion protein 1	0	13	0	13
Leukotriene B4 receptor 2	0	1	1	3
PPM1D protein	10	0	0	10
Sterol O-acyltransferase 1	0	3	0	3
Sterol O-acyltransferase 2	0	2	0	2
Myc proto-oncogene protein	0	1	0	1
Sterol O-acyltransferase 1	0	4	0	4
Dual specificity mitogen-activated protein kinase kinase 3	0	1	2	3
Sterol O-acyltransferase 1	0	1	1	2
Acyl-CoA:cholesterol acyltransferase	0	5	0	5
Chain A, TRYPSIN	0	1	0	1
Chain H, Thrombin heavy chain	0	1	0	1
Chain H, Thrombin heavy chain	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	0	1	0	1
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	0	1	0	1
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, TRYPSIN IVA	0	1	0	1
Chain A, trypsin II, anionic	0	1	0	1
Chain A, Trypsin II, anionic	0	1	0	1
Chain A, Trypsin II, anionic	0	1	0	1
Chain T, Trypsin II, anionic	0	1	0	1
Chain A, trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain T, Trypsin	0	1	0	1
Chain A, PROTEIN (TRYPSIN)	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	13	0	0	13
pyruvate kinase PKM isoform b	4	0	0	4
Prothrombin	0	4	4	8
Prothrombin	0	3	0	3
Coagulation factor X	0	2	0	2
Coagulation factor X	0	1	0	1
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	4	0	4
Acrosin	0	1	0	1
Ornithine decarboxylase	4	0	0	4
Aldehyde oxidase	0	3	0	5
Suppressor of tumorigenicity 14 protein	0	3	0	3
core protein, partial	0	1	0	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	24	0	0	24
Muscarinic acetylcholine receptor M2	0	9	2	13
Muscarinic acetylcholine receptor M4	0	8	2	12
Muscarinic acetylcholine receptor M5	0	8	2	12
Muscarinic acetylcholine receptor M1	0	11	2	15
Muscarinic acetylcholine receptor M3	0	10	2	14
Glutamate receptor ionotropic, NMDA 2D	0	2	4	6
Glutamate receptor ionotropic, NMDA 3B	0	1	3	4
Bile salt export pump	0	15	0	15
5-hydroxytryptamine receptor 4	0	14	3	17
Muscarinic acetylcholine receptor M1	0	3	5	10
Muscarinic acetylcholine receptor M3	0	3	5	9
Muscarinic acetylcholine receptor M4	0	3	4	8
Muscarinic acetylcholine receptor M5	0	3	4	8
Muscarinic acetylcholine receptor M2	0	3	4	8
Peroxisome proliferator-activated receptor alpha	0	0	5	5
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Peroxisome proliferator-activated receptor delta	0	0	3	4
Peroxisome proliferator-activated receptor alpha	5	3	8	17
Glutamate receptor ionotropic, NMDA 2C	0	2	4	6
Glutamate receptor ionotropic, NMDA 3A	0	1	3	4
Caspase-7	3	0	0	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
apical membrane antigen 1, AMA1	7	0	0	7
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	2
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Angiotensin-converting enzyme	0	8	1	10
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	1	4	5
Solute carrier family 22 member 1	0	6	0	9
endonuclease IV	9	0	0	9
Nrf2	2	0	0	2
peripheral myelin protein 22 isoform 1	18	0	0	18
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
M-phase phosphoprotein 8	13	0	0	13
Aldo-keto reductase family 1 member B10	0	3	0	3
Pancreatic triacylglycerol lipase	0	4	0	6
Estrogen receptor	0	14	3	18
Amyloid-beta precursor protein	1	9	1	11
Aldo-keto reductase family 1 member B1	0	19	0	19
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Aldo-keto reductase family 1 member C4	0	3	0	3
Sodium-dependent noradrenaline transporter	0	18	1	19
Mitogen-activated protein kinase 1	0	4	2	6
Aldo-keto reductase family 1 member C3	0	5	0	5
Aldo-keto reductase family 1 member C2	0	3	0	3
Aldo-keto reductase family 1 member C1	0	3	0	3
Integrase	0	3	0	3
ClpP	2	0	0	2
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
TSHR protein	2	0	0	2
LacZ protein (plasmid)	0	0	1	1
XBP1	0	1	0	1
serine-protein kinase ATM isoform a	5	0	0	5
hexokinase-4 isoform 1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
type-1 angiotensin II receptor	0	1	0	1
glucokinase regulatory protein	1	0	0	1
apelin receptor	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
DNA damage-inducible transcript 3 protein	0	1	0	1
Vpr	5	0	0	5
streptokinase A precursor	0	0	5	5
neuropeptide S receptor isoform A	13	0	0	13
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
heat shock protein 90, putative	0	0	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	6	1	8
Vitamin D3 receptor	0	5	6	14
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	4	6
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	1	3
Vitamin D3 receptor	0	1	1	2
Transporter	0	2	0	2
Vitamin D3 receptor A	0	0	2	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Thrombopoietin	6	0	0	6
Metallo-beta-lactamase type 2	0	1	1	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	1	0	1
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	9	0	10
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	4	0	4
Angiotensin-converting enzyme	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Beta-lactamase	0	3	0	4
Beta-lactamase	0	3	0	3
Angiotensin-converting enzyme 2	0	3	5	8
Beta-lactamase class B VIM-2	0	1	1	2
thyrotropin-releasing hormone receptor	8	0	0	8
Neuronal acetylcholine receptor subunit alpha-3	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	3	0	3
Muscarinic acetylcholine receptor M1	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-9	0	2	0	2
Muscarinic acetylcholine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	0	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Retinoic acid receptor RXR-alpha	0	1	1	2
Ileal sodium/bile acid cotransporter	0	2	0	2
Bile acid receptor	0	0	1	1
Bile acid receptor	0	3	4	7
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	5	6
Replicase polyprotein 1ab	0	2	5	7
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	5	6
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	3	5	8
Replicase polyprotein 1a	0	1	6	7
Replicase polyprotein 1ab	0	1	5	6
Replicase polyprotein 1ab	0	5	5	10
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	6	5	11
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	2	5
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	4	2	6
Beta-secretase 1	0	4	1	5
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	2	0	2
Cysteine proteinase falcipain 2a	0	1	0	1
Glycine receptor subunit alpha-1	0	0	2	2
Cholesterol 24-hydroxylase	0	1	1	2
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Phospholipase A2	0	1	1	2
G-protein coupled bile acid receptor 1	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	7	0	12
Solute carrier family 22 member 1	0	10	0	16
Solute carrier family 22 member 2	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Solute carrier family 22 member 2	0	6	0	8
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
ATP-dependent translocase ABCB1	0	5	0	5
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	6	0	7
Histamine H2 receptor	0	9	2	11
Histamine H1 receptor	0	1	4	5
Potassium-transporting ATPase subunit beta	0	1	0	1
Cytochrome P450 2J2	0	7	0	7
Solute carrier family 22 member 6	0	3	0	7
Multidrug and toxin extrusion protein 2	0	5	0	5
Solute carrier family 22 member 8	0	5	0	8
Histamine H4 receptor	0	2	2	4
Solute carrier family 22 member 11	0	2	0	5
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	3	0	4
Peroxisome proliferator-activated receptor alpha	0	0	3	3
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	4	2	6
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	1	0	2
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	4	0	6
General amino-acid permease GAP1	0	0	0	1
cytochrome P450 2D6 isoform 1	13	0	0	13
pregnane X receptor	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
5-hydroxytryptamine receptor 1A	0	3	1	4
Solute carrier family 2, facilitated glucose transporter member 1	0	1	1	2
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Adenylate cyclase type 1	0	1	1	3
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
Solute carrier family 22 member 3	0	3	0	4
Solute carrier family 22 member 3	0	1	0	1
C-8 sterol isomerase	0	3	0	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	4	1	5
dopamine D1 receptor	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	10	1	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	2	3	5
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	2	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
P53	1	0	0	1
RPL19A	0	0	1	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	1	5
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	2	3
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	3	0	3
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Neuraminidase	0	3	0	3
pyruvate kinase	2	0	0	2
cytochrome P450 2C9 precursor	13	0	0	13
histone deacetylase 9 isoform 3	6	0	0	6
rac GTPase-activating protein 1 isoform a	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Tyrosinase	0	2	0	2
Urease subunit alpha	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX12	0	2	0	2
Amine oxidase [flavin-containing] A	0	6	0	7
UDP-glucuronosyltransferase 1A1	0	5	0	8
UDP-glucuronosyltransferase 1A4	0	1	0	3
Amine oxidase [flavin-containing] B	0	6	0	7
Proteasome subunit beta type-5	0	4	0	4
Estrogen receptor	0	0	1	1
Urease subunit beta	0	4	0	4
Substance-K receptor	0	2	0	2
Estrogen receptor beta	0	9	3	12
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Prenyltransferase homolog	0	0	0	1
Estrogen receptor beta	0	0	1	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	6
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Multidrug resistance-associated protein 1	0	4	1	8
Solute carrier organic anion transporter family member 1A2	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	2	0	5
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Thymidine kinase, cytosolic	0	3	0	6
Deoxycytidine kinase	0	0	2	3
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
Solute carrier organic anion transporter family member 1C1	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Beta-1 adrenergic receptor	0	4	1	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	9	0	9
D(2) dopamine receptor	0	7	0	7
Alpha-1B adrenergic receptor	0	22	1	23
Substance-K receptor	0	10	0	10
D(1A) dopamine receptor	0	7	0	8
5-hydroxytryptamine receptor 2C	0	14	0	14
Sodium-dependent serotonin transporter	0	16	1	17
D(3) dopamine receptor	0	11	0	11
Vasopressin V1a receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	16	0	16
Alpha-1A adrenergic receptor	0	22	2	24
Estrogen-related receptor gamma	0	1	1	2
UDP-glucose 4-epimerase	0	1	0	1
Cysteinyl leukotriene receptor 1	0	2	0	2
Cereblon isoform 4	0	3	0	3
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	5	0	5
Prostaglandin E2 receptor EP1 subtype	0	3	3	6
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	4	2	6
Prostaglandin E2 receptor EP2 subtype	0	3	2	5
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	1	2
Solute carrier family 22 member 7	0	1	0	4
Solute carrier organic anion transporter family member 2A1	0	2	0	2
Solute carrier family 22 member 7	0	1	0	3
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	3	0	0	3
isocitrate dehydrogenase 1, partial	5	0	0	5
LANA	0	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
eyes absent homolog 2 isoform a	3	0	0	3
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Exopolyphosphatase PRUNE1	0	1	0	1
Rap guanine nucleotide exchange factor 4	7	0	0	7
Single-stranded DNA cytosine deaminase	2	0	0	2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Acetylcholinesterase	0	5	1	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
Acetylcholinesterase	0	3	0	3
5-hydroxytryptamine receptor 1A	0	12	1	13
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	3	1	4
Acetylcholinesterase	0	4	0	4
Acetylcholinesterase	0	3	0	3
Glycogen synthase kinase-3 beta	0	3	2	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Cholinesterase	0	2	0	2
Acetylcholine receptor subunit epsilon	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Cytochrome P450 1B1	0	3	1	4
Carboxylic ester hydrolase	0	2	0	4
Carboxylic ester hydrolase	0	4	0	4
Histamine H3 receptor	0	2	2	4
Alpha-1A adrenergic receptor	0	2	1	3
Interstitial collagenase	0	4	1	5
Beta-2 adrenergic receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	3	1	4
Alpha-1D adrenergic receptor	0	5	1	6
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
Eyes absent homolog 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
5-hydroxytryptamine receptor 1B	0	7	1	8
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	4
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	2
Cytochrome P450 2B1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	3
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	2	3	5
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	2	3
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	3	3	6
Glycogen phosphorylase, liver form	0	1	2	3
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	1	2	3
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	2	3
Insulin-like growth factor 1 receptor	0	1	2	3
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	1	2	3
Tyrosine-protein kinase HCK	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Serine/threonine-protein kinase pim-1	0	1	3	4
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	1	2	3
ADP/ATP translocase 3	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	2	3
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	3	3	7
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	2	2	4
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	1	2	3
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	2	3	5
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	1	3	4
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	1	2	3
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	1	2	3
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	1	2	3
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	1	2	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	1	2	3
Cyclin-dependent-like kinase 5	0	2	2	4
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	1	2	3
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	2	3	5
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	1	2	3
Protein kinase C delta type	0	3	3	6
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	5	0	5
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	1	2	3
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
NPC1-like intracellular cholesterol transporter 1	0	3	0	3
Cathepsin B	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
fructose-bisphosphate aldolase	0	1	0	1
Fatty acid-binding protein, liver	0	2	2	4
Beta-3 adrenergic receptor	0	4	1	5
Cruzipain	0	3	0	3
Chloride channel isoform 1	0	0	1	1
Chain A, Dihydrofolate reductase	0	0	1	1
DNA polymerase beta	6	0	0	6
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	2
Dihydrofolate reductase	0	2	1	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Albumin	0	2	5	8
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
fructose-bisphosphate aldolase A	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Matrilysin	0	1	0	1
L-selectin	0	1	0	1
P-selectin	0	1	0	1
E-selectin	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	2
Autoinducer 2-binding periplasmic protein LuxP	0	1	0	1
Anthrax toxin receptor 2	0	2	0	2
Lactoperoxidase	0	2	0	3
Polypeptide N-acetylgalactosaminyltransferase 2	0	1	1	2
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Toll-like receptor 2	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Histone deacetylase 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Histone deacetylase 8	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	1	2	4
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Histone deacetylase 5	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
Thymidine kinase	0	2	0	3
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Thyroid hormone receptor alpha	0	4	6	10
Thyroid hormone receptor beta	0	4	6	10
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	8	0	9
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	4	0	4
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	4	0	4
Amino acid transporter	0	4	0	4
Glutathione reductase	0	1	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	9	0	10
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	2	4
Guanine deaminase	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	1	1	7
Macrophage migration inhibitory factor	0	2	0	2
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	2	0	2
Glutaminyl-peptide cyclotransferase	0	2	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
N-glycosylase/DNA lyase	0	1	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Chain A, Purine-nucleoside Phosphorylase	0	1	0	1
Chain C, Xanthine dehydrogenase/oxidase	0	0	1	1
Prostacyclin receptor	0	1	1	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	2	0	2
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	5
Aldo-keto reductase family 1 member B1	0	3	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Caspase-1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	3
C-X-C chemokine receptor type 3	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Estrogen receptor beta	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Chymotrypsinogen A	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	3	1	4
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	3	0	5
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	2	0	2
Lanosterol 14-alpha demethylase	0	0	0	1
14-alpha sterol demethylase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	5	0	5
Intestinal-type alkaline phosphatase	0	4	0	4
Phospholipase A-2-activating protein	0	4	0	4
Leukotriene B4 receptor 1	0	2	0	3
Cathepsin B	0	1	0	1
Papain	0	1	0	1
Serine protease hepsin	0	3	0	3
Plasminogen	0	1	0	1
Trypsin-1	0	3	0	3
Trypsin-2	0	2	0	2
Cathepsin B	0	3	0	3
Pro-cathepsin H	0	1	0	1
Trypsin-3	0	2	0	2
Calpain-1 catalytic subunit	0	1	0	1
Cathepsin K	0	1	0	1
Hepatocyte growth factor activator	0	3	1	4
Transmembrane protease serine 6	0	1	0	1
Cysteine protease	0	1	0	1
Cysteine protease falcipain-3	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	2	1	4
Tubulin beta chain	0	2	1	4
Tubulin alpha-3C chain	0	2	1	4
Tubulin alpha-1B chain	0	2	1	4
Tubulin alpha-4A chain	0	2	1	4
Tubulin beta-4B chain	0	2	1	4
DNA gyrase subunit A	0	3	0	4
DNA primase	0	2	0	2
Tubulin beta-3 chain	0	3	1	5
Tubulin beta-2A chain	0	2	1	4
Tubulin beta-8 chain	0	2	1	4
Tubulin alpha-3E chain	0	2	1	4
Tubulin alpha-1A chain	0	2	1	4
Tubulin alpha-1C chain	0	2	1	4
Tubulin beta-6 chain	0	2	1	4
Tubulin beta-2B chain	0	2	1	4
Tubulin beta-1 chain	0	2	1	4
Fatty acid-binding protein, heart	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Dual specificity protein phosphatase 3	0	1	0	1
Type-1 angiotensin II receptor	0	1	1	2
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	4	0	0	4
bcl-2-related protein A1	0	2	0	2
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	4	0	4
Integrin alpha-L	0	1	1	2
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Transcription factor SOX-18	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	3	0	3
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
Potassium channel subfamily K member 9	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	2	0	2
SUMO1 activating enzyme subunit 1	0	2	0	2
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	2	0	2
ubiquitin-conjugating enzyme E2 N	0	3	0	3
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Complement C1r subcomponent	0	1	0	1
Coagulation factor XII	0	2	0	2
Cathepsin D	0	1	0	1
Complement C1s subcomponent	0	1	0	1
Matrix metalloproteinase-9	0	3	0	3
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	3	0	3
D-amino-acid oxidase	0	1	0	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Phospholipase A2, membrane associated	0	0	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Beta-2 adrenergic receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	2	0	3
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
DNA topoisomerase 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	4
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Nitric oxide synthase, brain	0	1	0	1
Phosphatidylserine lipase ABHD16A	0	1	0	1
Lipoprotein lipase	0	1	0	1
Hepatic triacylglycerol lipase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Cannabinoid receptor 1	0	3	0	3
Kappa-type opioid receptor	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
Proteasome subunit beta type-2	0	1	0	1
Platelet-activating factor acetylhydrolase	0	2	0	2
Neutral cholesterol ester hydrolase 1	0	1	0	1
Diacylglycerol lipase-alpha	0	1	0	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Diacylglycerol lipase-beta	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Acyl-protein thioesterase 2	0	1	0	1
Diacylglycerol lipase-alpha	0	1	0	1
Endothelial lipase	0	1	0	1
Chain A, Pyruvate kinase, M2 isozyme	0	1	0	1
Chain A, Phosphonopyruvate hydrolase	0	1	0	1
Chain A, Phosphoenolpyruvate-protein phosphotransferase	0	1	0	1
Genome polyprotein	0	1	0	1
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	1	2
Beta-tubulin	0	1	0	1
Tubulin beta-2B chain	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
D	0	2	0	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	3
Alpha-1B adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	2
Alpha-2C adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	2
mu-type opioid receptor isoform MOR-1	0	0	2	2
5-hydroxytryptamine receptor 2A	0	0	2	2
Chain A, PROTEIN (CATECHOL OXIDASE)	0	1	0	1
Taste receptor type 2 member 38	0	0	1	3
Luciferin 4-monooxygenase	0	1	1	2
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	1	0	2
interferon gamma precursor	0	0	0	4
Beta-casein	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
D(4) dopamine receptor	0	4	0	4
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Alpha-2A adrenergic receptor	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Vascular cell adhesion protein 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Glutamate 5-kinase	0	0	0	1
Free fatty acid receptor 2	0	0	1	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
hexokinase	0	2	0	2
galactokinase	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Cytochrome P450 1A1	0	2	1	3
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Stromelysin-1	0	2	0	2
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	2	0	2
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Thromboxane-A synthase	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Nischarin	0	1	0	1
Nischarin	0	1	0	1
Sphingosine kinase 2	0	3	0	3
Sphingosine kinase 1	0	3	0	3
Niemann-Pick C1-like 1 protein	0	1	0	1
Niemann-Pick C1-like 1 protein	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
photoreceptor-specific nuclear receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	2	2	4
Cyclin-dependent kinase 18	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Laccase	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
NS5	0	0	1	1
RNA-directed RNA polymerase	0	0	1	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Estrogen receptor	0	0	2	3
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Estrogen receptor beta	0	0	2	3
Protein kinase C eta type	0	2	0	2
Protein kinase C theta type	0	2	0	2
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
DNA polymerase beta	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
fMet-Leu-Phe receptor	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 2	0	1	0	1
Protein kinase C gamma type	0	3	1	4
D(3) dopamine receptor	0	2	0	2
Protein kinase C eta type	0	2	1	3
P2X purinoceptor 2	0	1	1	2
P2Y purinoceptor 4	0	0	1	1
NAD-dependent protein deacetylase HST2	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
Protein kinase C epsilon type	0	3	1	4
Serine/threonine-protein kinase D1	0	2	1	3
Dual specificity protein phosphatase 5	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 8	0	1	0	1
RmtA	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
P2X purinoceptor 7	0	0	1	1
Protein arginine N-methyltransferase 1	0	1	0	1
Chain A, Oxysterols receptor LXR-beta	0	1	0	1
Chain A, Oxysterols receptor LXR-beta	0	1	0	1
Nuclear receptor ROR-alpha	0	2	1	3
Alpha-glucosidase MAL32	0	1	0	1
Presenilin-1	0	1	1	2
Presenilin-2	0	1	1	2
Oxysterols receptor LXR-beta	0	2	2	4
Oxysterols receptor LXR-beta	0	0	1	1
Oxysterols receptor LXR-beta	0	0	1	1
Gamma-secretase subunit APH-1B	0	1	1	2
Nicastrin	0	1	1	2
Nuclear receptor ROR-beta	0	1	1	2
Gamma-secretase subunit APH-1A	0	1	1	2
Gamma-secretase subunit PEN-2	0	1	1	2
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, liver Carboxylesterase I	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
[Tau protein] kinase	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Cytochrome P450 2E1	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	2	2
Acyl-CoA desaturase 1	0	1	0	1
Trypanothione reductase	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Gastrotropin	0	0	1	1
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Transporter	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
Squalene synthase	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Substance-P receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Phospholipase D1	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Chitotriosidase-1	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Serine palmitoyltransferase 1	0	0	1	1
Serine palmitoyltransferase 2	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
P2Y purinoceptor 13	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Endolysin	0	0	1	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Forkhead box protein M1	0	2	0	2
ATP-binding cassette sub-family C member 8	0	1	0	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
D(3) dopamine receptor isoform e	1	0	0	1
trace amine-associated receptor 1	0	1	1	2
Phenylethanolamine N-methyltransferase	0	1	0	1
Dopamine beta-hydroxylase	0	0	0	1
5-hydroxytryptamine receptor 6	0	0	1	1
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Histamine H3 receptor	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Beta-1,4-galactosyltransferase 1	0	0	0	1
N-acetyllactosaminide alpha-1,3-galactosyltransferase	0	0	0	1
P2Y purinoceptor 14	0	0	1	1
Chain A, Arginase 1	0	1	0	1
Glycoprotein	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Guanylate cyclase soluble subunit alpha-1	0	0	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Apolipoprotein B-100, Familial Defective

Synonyms(18)

Research Excerpts

Overview

Context

Treatment

Research

Studies (2,835)

Protein Targets (2,397)

Apolipoprotein B-100, Familial Defective

Synonyms(18)

Research Excerpts

Overview

Context

Treatment

Research

Studies (2,835)

Drugs Studied (522)

Protein Targets (2,397)