kryptopyrrole profile

Kryptopyrrole is a porphyrin derivative that has been proposed to play a role in various health conditions, including mental health issues, fatigue, and allergies. It is a naturally occurring compound found in small amounts in the body and is thought to be produced as a byproduct of heme synthesis. The exact mechanisms by which kryptopyrrole may exert its effects are not fully understood. Some studies suggest that it may interfere with neurotransmitter function, particularly with the metabolism of pyridoxine (vitamin B6). However, the evidence for these effects is limited and more research is needed. Kryptopyrrole is often studied in the context of alternative medicine and is sometimes used in conjunction with other therapies for conditions such as anxiety, depression, and chronic fatigue syndrome. However, its use is not supported by mainstream medical science and there is no clear consensus on its effectiveness or safety. Furthermore, there is no standard test for kryptopyrrole, and the interpretation of test results is often controversial. It is important to consult with a qualified healthcare professional before using any supplement or treatment related to kryptopyrrole.'

kryptopyrrole: metabolite in schizophrenia [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	10600
SCHEMBL ID	891315
MeSH ID	M0058525

Synonym
AC-1902
brn 0107089
3-ethyl-2,4-dimethyl-1h-pyrrole
nsc 62025
einecs 208-234-7
1h-pyrrole, 3-ethyl-2,4-dimethyl-
pyrrole, 3-ethyl-2,4-dimethyl-
kryptopyrrole
2,4-dimethyl-3-ethylpyrrole
nsc-62025
3-ethyl-2,4-dimethylpyrrole
517-22-6
cryptopyrrole
kryptopyrrol
nsc62025
3-ethyl-2,4-dimethylpyrrole, 97%
E0555
A7616
2,4-dimethyl-3-ethyl-1h-pyrrole
AKOS006221229
unii-339v6s6pps
339v6s6pps ,
5-20-05-00099 (beilstein handbook reference)
FT-0610156
SCHEMBL891315
W-105871
DTXSID20199647
mfcd00005222
D70970
F0001-1346
SY051106
FS-5219
SB63946
CS-W016572
EN300-176676
3-ethy-2,4-dimethyl-1h-pyrrole
Z1203730732

Excerpt	Relevance	Reference
" 4 Dose-response curves to exogenous acetylcholine in guinea-pig ileum were shifted to the right by kryptopyrrole, with loss of parallelism and reduction in the maximum contraction."	( Pharmacological properties of kryptopyrrole and its oxidation products on isolated sciatic nerve of rat and on guinea-pig ileum. Gorchein, A; Mitchell, LD; Rogers, AT, 1979)	0.76

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (85.71)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (14.29)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (14.29%)	5.53%
Reviews	1 (14.29%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (71.43%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	5.84	7	1	pyrrole; secondary amine
vitamin b 6 Vitamin B 6: VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.	3.41	1	0
2-hydroxyhemopyrroline-5-one 2-hydroxyhemopyrroline-5-one: structure	3.41	1	0
linoleic acid Linoleic Acid: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed). linoleic acid : An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.	1.96	1	0	octadecadienoic acid; omega-6 fatty acid	algal metabolite; Daphnia galeata metabolite; plant metabolite
alprostadil [no description available]	1.96	1	0	prostaglandins E	anticoagulant; human metabolite; platelet aggregation inhibitor; vasodilator agent

Condition	Relationship Strength	Studies	Trials
Deficiency, Pyridoxine [description not available]	3.23	1	0
Porphyria [description not available]	3.59	3	0
Dementia Praecox [description not available]	3.81	4	0
Porphyrias A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.	3.59	3	0
Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.	3.81	4	0
Hyperactivity, Motor [description not available]	3.34	1	1
Academic Disorder, Developmental [description not available]	3.34	1	1
Learning Disabilities Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.	3.34	1	1
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	1.95	1	0
Symptom Cluster [description not available]	1.96	1	0
Syndrome A characteristic symptom complex.	1.96	1	0

kryptopyrrole

Description

Cross-References

Synonyms (37)

Research Excerpts

Dosage Studied

Research

Studies (7)

Market Indicators

Research Demand Index: 50.27

Study Types