Page last updated: 2024-09-27

Cerebral Small Vessel Diseases

Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, hypertension and risk factors for lacunar infarcts (see LACUNAR INFARCTION); LEUKOARAIOSIS; and CEREBRAL HEMORRHAGE.

Synonyms(1)

Synonym
Cerebral Small Vessel Diseases

Research

Studies (179)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's96 (53.63)28.8240
2020's83 (46.37)9.53
DrugIndicatedRelationship StrengthStudiesTrials
betaine0low10
carnitine0low10
choline0low10
n(g),n(g')-dimethyl-l-arginine0low10
nickel0low10
niacinamide0low10
spermidine0low10
trimethyloxamine0low10
uric acid0low40
urea0low10
amlodipine0low10
aspirin0medium31
caffeine0medium11
celecoxib0low10
gabapentin0low10
haloperidol0low10
iofetamine0low10
losartan0low10
apnea0low10
nimodipine0medium32
nitroglycerin0low20
ticlopidine0low10
desoxycorticosterone acetate0low20
aspartic acid0low10
phlorhizin0low10
arginine0low30
isosorbide dinitrate0medium22
thiazoles0medium101
alpha-aminopyridine0low10
methamphetamine0low10
glycerylphosphorylcholine0medium22
acetylcysteine0low10
s,n,n'-tripropylthiocarbamate0low20
manganese0low10
chromium0low10
gadolinium0low30
isosorbide-5-mononitrate0medium44
nicergoline0low10
clopidogrel0medium31
atorvastatin0low10
3-n-butylphthalide0medium21
glucose, (beta-d)-isomer0low10
n-acetylaspartic acid0low10
1,7-phenanthroline0low10
fluorodeoxyglucose f180low20
rivastigmine0low10
fibrinogen0low30
homocysteine0low150
vitamin b 60low10
prolinedithiocarbamate0low10
tadalafil0medium11
n,n-dimethylarginine0low10
glycerophosphoinositol 4,5-bisphosphate0low10
proline0low10
angiotensin ii0low10
vasobral0medium11
dabigatran0low10
benzofurans0medium31
dihydropyridines0medium11
nicotinamide-beta-riboside0low10
eplerenone0low10
vinpocetine0medium11
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole0medium101
nitrogen dioxide0low30
osteoprotegerin0low20
bilirubin0low10
dinoprost0low10
vitamin k semiquinone radical0low10
8-epi-prostaglandin f2alpha0low10
4-hydroxy-2-nonenal0low10
lysophosphatidylcholines0low30
cysteine0low30
dihydroergotoxine0medium11
salvianolic acid B0low10
gadolinium dtpa0low20
mocetinostat0low20
rivaroxaban0low10
k 134 compound0low10
apixaban0low10
alpha-synuclein0low10
c-peptide0low10
calpain0low10
florbetapir f 180low10
glycolipids0low10
piperidines0low10
interleukin-80low10
natriuretic peptide, brain0low10
warfarin0low20
epidermal growth factor0low10
transforming growth factor beta0low80
vitamin b 120low20
amyloid beta-peptides0low30
folic acid0low20
neopterin0low10
eye0low10
technetium tc 99m bicisate0low10
leptin0low20

Protein Targets (783)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
geminin160016
lamin isoform A-delta10140014
Guanine nucleotide-binding protein G3003
Amyloid-beta precursor protein0202
Glutamate receptor ionotropic, NMDA 1 0404
Glutamate receptor ionotropic, NMDA 2A 0303
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0303
Glutamate receptor ionotropic, NMDA 2D0303
Glutamate receptor ionotropic, NMDA 3B0303
Glutamate receptor ionotropic, NMDA 3A0303
Microtubule-associated protein tau7007
vitamin D3 receptor isoform VDRA8008
Transient receptor potential cation channel subfamily A member 10011
aldehyde dehydrogenase 1 family, member A1120012
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, 2-oxoglutarate Oxygenase7007
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
acetylcholinesterase6006
dopamine D1 receptor1001
15-lipoxygenase, partial3003
pregnane X receptor2002
phosphopantetheinyl transferase5005
RAR-related orphan receptor gamma8008
USP1 protein, partial9009
NFKB1 protein, partial4004
Thrombopoietin4004
AR protein190019
regulator of G-protein signaling 44004
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha9009
farnesoid X nuclear receptor7007
estrogen nuclear receptor alpha210021
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
arylsulfatase A8008
euchromatic histone-lysine N-methyltransferase 2180018
Bloom syndrome protein isoform 18008
D(1A) dopamine receptor4004
thyroid hormone receptor beta isoform a6006
thyroid hormone receptor beta isoform 2120012
heat shock protein beta-13003
flap endonuclease 14004
peripheral myelin protein 226006
survival motor neuron protein isoform d5005
muscarinic acetylcholine receptor M18008
Histone deacetylase 30404
Solute carrier family 22 member 60202
Histone deacetylase 40303
Histone deacetylase 10505
Histone deacetylase 70303
Histone deacetylase 20505
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0303
Ataxin-25005
Histone deacetylase 80303
Histone deacetylase 60404
Histone deacetylase 90202
Histone deacetylase 50303
ATP-dependent phosphofructokinase8008
thyroid stimulating hormone receptor7007
Voltage-dependent calcium channel gamma-2 subunit6006
Heat shock protein HSP 90-alpha0011
Botulinum neurotoxin type A 0101
Neutrophil cytosol factor 10101
Glutamate receptor 26006
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0203
Nitric oxide synthase, brain 0203
Nitric oxide synthase, inducible0114
Kappa-type opioid receptor0112
Phosphatidylinositol 4-kinase alpha0101
Mu-type opioid receptor0213
Tyrosine-protein kinase 0011
Phosphatidylinositol 4-kinase type 2-beta0101
Phosphatidylinositol 4-kinase type 2-alpha0101
Phosphatidylinositol 4-kinase beta0101
Chain A, Ferritin light chain6006
acid sphingomyelinase3003
TDP1 protein120012
Smad32002
cytochrome P450 family 3 subfamily A polypeptide 4140014
G110011
cytochrome P450 2D6120012
IDH13003
chromobox protein homolog 19009
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
nuclear receptor ROR-gamma isoform 16006
histone acetyltransferase KAT2A isoform 17007
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010011
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium channel subfamily K member 20224
Bile salt export pump018018
Interferon beta140014
HLA class I histocompatibility antigen, B alpha chain 110011
ATP-dependent translocase ABCB10406
Alpha-2A adrenergic receptor0606
Alpha-2C adrenergic receptor0606
Alpha-2B adrenergic receptor0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Alpha-1A adrenergic receptor0202
Alpha-1B adrenergic receptor0202
5-hydroxytryptamine receptor 60303
Spike glycoprotein8008
Sodium-dependent dopamine transporter 0404
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Potassium channel subfamily K member 2 0101
Inositol hexakisphosphate kinase 1110011
Canalicular multispecific organic anion transporter 1010010
cytochrome P450 2C9, partial110011
glucocerebrosidase4004
DNA polymerase kappa isoform 16006
Atrial natriuretic peptide receptor 30202
Type-1A angiotensin II receptor 0426
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0404
Type-1 angiotensin II receptor0439
Type-2 angiotensin II receptor0404
Type-2 angiotensin II receptor0303
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)0101
EWS/FLI fusion protein130013
Coagulation factor X0101
Prothrombin0404
Coagulation factor X0505
Trypsin-10202
Trypsin-20202
Trypsin-30202
thioredoxin reductase100010
ATAD5 protein, partial6006
estrogen-related nuclear receptor alpha150015
neuropeptide S receptor isoform A3003
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
GLS protein6006
thyroid stimulating hormone receptor9009
alpha-galactosidase2002
cytochrome P450 2C19 precursor4004
DNA polymerase iota isoform a (long)7007
lethal factor (plasmid)7007
Cytochrome P450 3A40204
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, inducible0001
Cationic amino acid transporter 30202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10607
Carbonic anhydrase 20607
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase 40203
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
GTP-binding protein (rab7)0022
ras protein, partial0022
interleukin 81001
hypothetical protein, conserved1001
peroxisome proliferator-activated receptor delta6006
Rac1 protein0022
cell division cycle 42 (GTP binding protein, 25kDa), partial0022
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0303
Prostaglandin G/H synthase 2 0303
Epidermal growth factor receptor0101
Fatty acid-binding protein, liver0101
Integrin beta-30101
Myeloperoxidase0101
Prostaglandin G/H synthase 10202
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb0101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10405
Adenosine receptor A10506
Adenosine receptor A2a0507
Substance-P receptor0101
Prostaglandin G/H synthase 20618
Urotensin-2 receptor0202
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma2002
Ras-related protein Rab-2A0022
Gamma-aminobutyric acid receptor subunit alpha-15207
Prostaglandin G/H synthase 20303
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10516
Sigma non-opioid intracellular receptor 10213
Chain A, Cruzipain5005
SMAD family member 23003
SMAD family member 33003
GLI family zinc finger 3130013
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 39009
pregnane X nuclear receptor110011
peroxisome proliferator activated receptor gamma5005
caspase-34004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
Caspase-73003
caspase-33003
nuclear factor erythroid 2-related factor 2 isoform 17007
Solute carrier organic anion transporter family member 2B1 0001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Cellular tumor antigen p535005
Insulin receptor 0101
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Solute carrier organic anion transporter family member 1B30406
Broad substrate specificity ATP-binding cassette transporter ABCG20404
Solute carrier organic anion transporter family member 1B10507
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Bile salt export pump0202
Proton-coupled amino acid transporter 10202
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
caspase-1 isoform alpha precursor1001
Caspase-71001
Inositol monophosphatase 11001
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0022
Chain A, glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Chitinase0101
v-jun sarcoma virus 17 oncogene homolog (avian)6006
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta2002
Glycogen phosphorylase, muscle form0202
Renin0101
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30404
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0303
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0202
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, Carbonic anhydrase II0101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
glp-1 receptor, partial6006
hypoxia-inducible factor 1 alpha subunit1001
PPM1D protein5005
progesterone receptor8008
Carbonic anhydrase 0101
Carbonic anhydrase 0101
67.9K protein2002
Carbonic anhydrase0101
activating transcription factor 63003
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
Histone H2A.x2002
interferon gamma precursor0001
prostaglandin E2 receptor EP2 subtype0001
nuclear factor erythroid 2-related factor 2 isoform 24004
potassium voltage-gated channel subfamily H member 2 isoform d7007
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi5005
Prostaglandin E synthase0101
3-phosphoinositide-dependent protein kinase 10101
Carbonic anhydrase 120202
cGMP-specific 3',5'-cyclic phosphodiesterase0314
Cytochrome c oxidase subunit 10101
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20101
Carbonic anhydrase 30202
Procathepsin L0101
Aldo-keto reductase family 1 member B10404
Neuronal acetylcholine receptor subunit alpha-40202
Polyunsaturated fatty acid 5-lipoxygenase0101
Quinolone resistance protein NorA0101
Cytochrome P450 2D60303
Cytochrome P450 2C9 0707
Neuronal acetylcholine receptor subunit beta-20202
Beta-3 adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit beta-15005
Alpha-1B adrenergic receptor0404
Calpain-2 catalytic subunit0101
Alpha-2B adrenergic receptor0606
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
5-hydroxytryptamine receptor 1A0404
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
D(1A) dopamine receptor0405
Prostaglandin G/H synthase 10101
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Sodium-dependent noradrenaline transporter 0415
Cruzipain0101
Sodium/hydrogen exchanger 10101
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Indoleamine 2,3-dioxygenase 10101
Gamma-aminobutyric acid receptor subunit alpha-65005
Sodium-dependent serotonin transporter0718
Sodium-dependent serotonin transporter0314
Delta-type opioid receptor0303
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Bifunctional epoxide hydrolase 20202
Carbonic anhydrase 5A, mitochondrial0202
Prostaglandin G/H synthase 2 0101
Carbonic anhydrase0101
Alpha-1A adrenergic receptor0404
Carbonic anhydrase 70202
Carbonic anhydrase0101
D(2) dopamine receptor0303
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Prostaglandin G/H synthase 20101
Mitogen-activated protein kinase 140101
Carbonic anhydrase 90303
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Prostaglandin G/H synthase 1 0101
Carbonic anhydrase 0101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 130101
Cyclooxygenase-2 0101
Rap guanine nucleotide exchange factor 44004
GABA theta subunit5005
ATPase family AAA domain-containing protein 53003
Carbonic anhydrase 150202
P2Y purinoceptor 120101
Gamma-aminobutyric acid receptor subunit epsilon5005
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0202
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20103
Solute carrier family 22 member 1 0103
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10102
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
endonuclease IV2002
bromodomain adjacent to zinc finger domain 2B3003
peripheral myelin protein 22 isoform 14004
cytochrome P450 2C9 precursor3003
mitogen-activated protein kinase 12002
M-phase phosphoprotein 83003
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Histamine H2 receptor3004
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0404
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0404
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0505
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0404
nonstructural protein 13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
Cytochrome P450 2C80202
Cytochrome P450 2B60303
Liver carboxylesterase 10001
Cytochrome P450 2C190505
P2Y purinoceptor 120202
Plasminogen0101
Coagulation factor XII0202
Tissue-type plasminogen activator0101
Vitamin K-dependent protein C0101
Serine protease hepsin0101
Muscarinic acetylcholine receptor M10303
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10202
thioredoxin glutathione reductase4004
Chain A, Beta-lactamase6006
serine-protein kinase ATM isoform a1001
mu-type opioid receptor isoform MOR-10011
importin subunit beta-1 isoform 12002
fatty acid synthase0101
snurportin-12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
5-hydroxytryptamine receptor 2A0011
Thromboxane A2 receptor 0214
Prostaglandin E2 receptor EP1 subtype0112
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0213
Prostaglandin E2 receptor EP3 subtype0112
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin F2-alpha receptor0011
Prostacyclin receptor0101
Solute carrier organic anion transporter family member 2A10102
Prostaglandin D2 receptor0101
Solute carrier family 22 member 60002
Solute carrier family 22 member 70001
Solute carrier family 22 member 80102
Solute carrier organic anion transporter family member 2A10102
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
GALC protein1001
Estrogen receptor0112
Glucocorticoid receptor0213
Progesterone receptor0213
Mineralocorticoid receptor 0213
Androgen receptor0112
Mineralocorticoid receptor0202
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Estrogen receptor beta0112
Chain A, Dihydrofolate reductase0011
lysosomal alpha-glucosidase preproprotein1001
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Alpha-synuclein1001
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Asialoglycoprotein receptor 10112
Fumarate hydratase2002
polyprotein2002
Adenylate cyclase type 1 0101
cytochrome P450 2D6 isoform 12002
serine/threonine-protein kinase mTOR isoform 12002
transient receptor potential cation channel subfamily V member 11001
Cocaine esterase0101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transient receptor potential cation channel subfamily V member 10101
UDP-glucuronosyltransferase 1A90102
5-hydroxytryptamine receptor 40202
Albumin0022
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10202
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 1A0202
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50202
Beta-2 adrenergic receptor0202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10202
Angiotensin-converting enzyme0101
Integrin alpha-40202
D(2) dopamine receptor0215
5-hydroxytryptamine receptor 2A0202
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70102
Beta-1 adrenergic receptor0101
D0202
D(3) dopamine receptor0202
D(2) dopamine receptor0202
Muscarinic acetylcholine receptor M30101
D(4) dopamine receptor0215
D(1B) dopamine receptor0203
Adenylate cyclase type 30101
UDP-glucuronosyltransferase 1A40001
Alpha-1D adrenergic receptor0202
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor0202
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
Histamine H1 receptor0202
5-hydroxytryptamine receptor 7 0101
C-8 sterol isomerase0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
Mu-type opioid receptor0213
D(3) dopamine receptor0215
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 2A0101
D(1A) dopamine receptor1102
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20303
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Sodium channel protein type 7 subunit alpha0101
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
Potassium voltage-gated channel subfamily H member 20505
TAR DNA-binding protein 432002
5-hydroxytryptamine receptor 40101
Sodium channel protein type 5 subunit alpha0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0303
Adenylyl cyclase 7 0101
D0101
Sodium channel protein type 2 subunit alpha0101
Transient receptor potential cation channel subfamily V member 40101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10203
Neprilysin0101
Angiotensin-converting enzyme 0202
Type-1 angiotensin II receptor0112
Squalene synthase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Platelet glycoprotein VI0113
Type-1 angiotensin II receptor0112
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
Solute carrier family 22 member 30101
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] B0101
Synaptic vesicular amine transporter0202
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Nuclear receptor corepressor 10101
Leukotriene A-4 hydrolase0101
Nuclear receptor corepressor 20101
transcriptional regulator ERG isoform 31001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Atrial natriuretic peptide receptor 10101
Chain A, NAD-dependent deacetylase0101
aryl hydrocarbon receptor5005
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Parkin1001
Voltage-dependent L-type calcium channel subunit beta-40101
Voltage-dependent P/Q-type calcium channel subunit alpha-1A0101
Voltage-dependent T-type calcium channel subunit alpha-1G0101
Voltage-dependent calcium channel gamma-3 subunit0101
Nuclear receptor subfamily 1 group I member 20011
Voltage-dependent T-type calcium channel subunit alpha-1H0101
Cannabinoid receptor 10202
Voltage-dependent L-type calcium channel subunit beta-30101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel gamma-7 subunit0101
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Voltage-dependent L-type calcium channel subunit beta-10101
Voltage-dependent calcium channel gamma-1 subunit0101
Voltage-dependent L-type calcium channel subunit beta-20101
Voltage-dependent R-type calcium channel subunit alpha-1E0101
Voltage-dependent calcium channel subunit alpha-2/delta-40101
Transient receptor potential cation channel subfamily A member 10011
Voltage-dependent calcium channel subunit alpha-2/delta-30101
Voltage-dependent calcium channel gamma-8 subunit0101
Bile acid receptor0101
Voltage-dependent calcium channel gamma-6 subunit0101
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Voltage-dependent T-type calcium channel subunit alpha-1I0101
Voltage-dependent calcium channel gamma-4 subunit0101
Voltage-dependent calcium channel gamma-5 subunit0101
Voltage-dependent calcium channel gamma-2 subunit0101
Sodium/nucleoside cotransporter 10101
Sodium/nucleoside cotransporter 20101
Pancreatic triacylglycerol lipase0101
Sodium/glucose cotransporter 10213
Sodium/glucose cotransporter 20213
Sodium/glucose cotransporter 1 0101
Sodium/glucose cotransporter 20101
Equilibrative nucleoside transporter 10101
Solute carrier family 28 member 30101
Solute carrier family 5 member 40101
Prostaglandin D2 receptor 20101
Glutamate 5-kinase0001
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Chain A, Activated Factor Xa Heavy Chain0101
Suppressor of tumorigenicity 14 protein0101
Acetylcholinesterase0101
Acetylcholinesterase0101
Acyl-CoA desaturase 10101
Acetylcholine receptor subunit epsilon0101
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0202
Acetylcholinesterase 0101
Cholinesterase0101
Acetylcholinesterase0202
Tyrosine-protein kinase SYK0101
Beta-secretase 10101
Cholinesterase0112
Cholinesterase0101
Carboxylic ester hydrolase 0101
Carboxylic ester hydrolase 0101
Lysine-specific histone demethylase 1A0101
DNA topoisomerase 2-alpha0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0202
Pyruvate kinase PKM0101
Cannabinoid receptor 10101
Sulfate anion transporter 10001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
Carbonic anhydrase 130101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0202
GTP-binding nuclear protein Ran isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0202
Nuclear receptor subfamily 2 group E member 10011
Caspase-10101
Serine/threonine-protein kinase PLK10101
Serine/threonine-protein kinase PLK30101
Serine/threonine-protein kinase PLK20101
Luciferase1001
Disintegrin and metalloproteinase domain-containing protein 171001
Rap guanine nucleotide exchange factor 32002
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Solute carrier family 2, facilitated glucose transporter member 90112
Hsf1 protein0011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]