Devic Disease

Synonym
Devic Syndrome
NMO Spectrum Disorder
Devic Neuromyelitis Optica
Neuromyelitis Optica (NMO) Spectrum Disorders
Neuromyelitis Optica Spectrum Disorder
Neuromyelitis Optica Spectrum Disorders
Devic's Syndrome
Neuromyelitis Optica (NMO) Spectrum Disorder
Devic's Neuromyelitis Optica
Devic's Disease
Devic Disease

Excerpt	Reference
"Devic's neuromyelitis optica is related to nosologic problems with multiple sclerosis."	( Bencherifa, F; Berraho, A; Bourassi, A; Mellal, Z, 2007)
"Devic's neuromyelitis optica is an inflammatory demyelinating disorder normally restricted to the optic nerves and spinal cord."	( Cavagna, S; Cavillon, G; Confavreux, C; Giraudon, P; Honnorat, J; Marignier, R; Nicolle, A; Rogemond, V; Touret, M; Varrin-Doyer, M; Watrin, C, 2010)
"Neuromyelitis optica spectrum disorder is an inflammatory syndrome that is associated with many autoimmune conditions."	( D, S; Kadhiravan, T; Moulitej, MMV; Pranov, R; Ramesh, A; Thabah, MM, 2019)

Excerpt	Reference
"However, Devic's neuromyelitis optica has also been seen in children."	( Senbil, N; Yavuz Gurer, YK; Yilmaz, D; Yuksel, D, 2007)

Excerpt	Reference
"Seven newly diagnosed patients with Devic's neuromyelitis optica were treated with long-term prednisone and azathioprine, and were followed every 2 months for at least 18 months."	( Ahmed, W; Dencoff, JE; Mandler, RN, 1998)
"Patients Twenty-four patients with NMO spectrum disorders (7 treatment-naive)."	( Carter, J; Jacob, A; Kantarci, OH; Keegan, BM; Lucchinetti, C; Matiello, M; Pittock, SJ; Shuster, E; Weinshenker, BG; Wingerchuk, DM, 2009)
"A 49-year-old female neuromyelitis optica spectrum disorder (NMOSD) patient with positive anti-aquaporin 4 (AQP4) antibody was treated with fingolimod (FTY720)."	( Fukaura, H; Izaki, S; Kubota, A; Mitsui, T; Narukawa, S; Nomura, K, 2013)
"We herein present a case of neuromyelitis optica spectrum disorder (NMOSD) combined with Sjögren's syndrome (SS) successfully treated with tacrolimus."	( Ge, P; Li, H; Liu, X; Liu, Y; Mu, W; Yang, W; Zhang, X; Zheng, X, 2014)
"Severe attacks of neuromyelitis optica spectrum disorder (NMO-SD) are improved by plasma exchange (PLEX) given as an adjunctive therapy."	( Bonnan, M; Cabre, P; Debeugny, S; Fergé, JL; Mehdaoui, H; Merle, H; Valentino, R, 2018)
"In India, Neuromyelitis optica spectrum disorders (NMOSD) can often be misdiagnosed as multiple sclerosis (MS) leading to wrong or delayed treatment."	( Acharya, R; Ahmad, F; Anadure, R; Gupta, A; Gupta, S; Hiremath, R; Purohit, P; Rehani, V; Soni, R, 2021)
"Fifty-nine neuromyelitis optica spectrum disorder patients accepted Mycophenolate Mofetil therapy for 1 year at least were divided into two groups: relapsing (n=21) and non-relapsing (n=38)."	( Chen, S; Jiao, X; Li, J; Liu, F; Liu, L; Luo, Z; Qiu, D; Shang, D; Wu, J; Zhou, X, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	26 (4.39)	23.3326
1990's	10 (1.69)	12.5806
2000's	71 (11.99)	18.1394
2010's	340 (57.43)	28.8240
2020's	145 (24.49)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	2	0
acetic acid	low	1	0
acetone	low	1	0
formic acid	low	1	0
carnitine	low	1	0
methane	low	2	0
choline	low	3	0
citric acid, anhydrous	low	1	0
chlorine	low	2	0
salicylic acid	low	1	0
n(g),n(g')-dimethyl-l-arginine	medium	1	1
creatine	low	2	0
lactic acid	low	3	0
glycine	low	4	0
hydrogen carbonate	low	1	0
kynurenine	low	1	0
inositol	low	3	0
niacin	low	1	0
nitrates	medium	1	1
nitrites	medium	1	1
picolinic acid	low	1	0
pyruvic acid	low	1	0
thiamine	low	3	0
uric acid	low	7	0
albendazole	low	1	0
aspirin	low	2	0
azathioprine	medium	95	3
bupivacaine	low	1	0
caffeine	low	1	0
carbamazepine	low	11	0
carmustine	medium	1	1
ci 994	low	1	0
clioquinol	low	1	0
pentetic acid	low	4	0
fentanyl	low	1	0
gabapentin	low	1	0
hydroxychloroquine	low	2	0
edaravone	low	1	0
memantine	low	1	0
methylphenidate	low	1	0
midazolam	low	1	0
mitoxantrone	medium	14	1
modafinil	low	2	0
apnea	low	1	0
omeprazole	low	1	0
pirenzepine	low	1	0
propidium	low	1	0
propofol	low	1	0
rizatriptan	low	1	0
sevoflurane	low	1	0
sulfamethoxazole	low	1	0
sumatriptan	low	1	0
trimethoprim	low	1	0
corticosterone	low	1	0
prednisolone	medium	36	1
thyroxine	low	2	0
prednisone	medium	20	1
triiodothyronine	low	1	0
alanine	low	2	0
serine	low	1	0
aspartic acid	low	4	0
lysine	low	1	0
leucine	low	1	0
cytarabine	medium	1	1
valine	low	1	0
threonine	low	1	0
tryptophan	low	4	0
arginine	medium	1	1
divinyl sulfone	low	1	0
methylprednisolone	medium	157	4
pyrrolidonecarboxylic acid	low	1	0
3-aminobenzoic acid	low	1	0
pyridostigmine bromide	low	3	0
pyrroles	low	1	0
homoarginine	medium	1	1
ephedrine	low	1	0
cuprizone	low	2	0
2-hydroxybutyric acid	low	1	0
glycyrrhizic acid	low	1	0
methylprednisolone hemisuccinate	low	3	0
carbonates	low	1	0
cladribine	low	3	0
n-methylaspartate	low	2	0
silver	low	1	0
gadolinium	medium	17	1
phenyl acetate	low	2	0
transferrin	low	1	0
glutamic acid	low	8	0
oxcarbazepine	low	1	0
etoposide	medium	1	1
propiconazole	low	2	0
simvastatin	low	2	0
itraconazole	low	1	0
atorvastatin	low	2	0
zanamivir	low	1	0
3-n-butylphthalide	low	1	0
n-acetylaspartic acid	low	4	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	4	0
n-acetylglutamic acid	low	1	0
tetrandrine	low	1	0
fibrinogen	low	2	0
homocysteine	low	1	0
vitamin b 6	low	1	0
imipenem, anhydrous	low	1	0
sivelestat	low	1	0
fingolimod hydrochloride	low	11	0
tanshinone	low	1	0
n,n-dimethylarginine	medium	1	1
methotrexate	low	6	0
phorbols	low	1	0
biotin	low	1	0
angiotensin ii	low	1	0
lacosamide	low	3	0
cortisone	low	1	0
benzofurans	low	1	0
bortezomib	medium	5	1
leupeptins	low	1	0
rocuronium	low	1	0
betadex	low	1	0
tacrolimus	low	6	0
cocaine	low	1	0
mycophenolic acid	low	47	0
melphalan	medium	1	1
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	1	0
dimethyl fumarate	low	6	0
mercaptopurine	low	1	0
D-fructopyranose	low	1	0
6-thioguanylic acid	low	1	0
methyl prednisolonate	low	1	0
myelin basic protein	low	21	0
sphingosine	low	6	0
bilirubin	low	2	0
linoleic acid	low	1	0
calcitriol	low	1	0
leukotriene b4	low	1	0
amphotericin b	low	1	0
humulene	low	1	0
glyceryl 2-arachidonate	low	1	0
fondaparinux	low	1	0
sphingosine 1-phosphate	low	1	0
topiramate	low	1	0
clobetasol	low	1	0
dextromethorphan	low	1	0
thyronines	low	1	0
carbocyanines	low	1	0
25-hydroxyvitamin d 2	low	1	0
1-palmitoyl-2-oleoylphosphatidylcholine	low	1	0
carbocyanine dye diic12(3)	low	1	0
gadolinium dtpa	low	7	0
etomoxir	low	1	0
mocetinostat	low	4	0
dimethylarginine	medium	1	1
alpha-synuclein	low	1	0
oxadiazoles	low	1	0
pituitrin	low	1	0
silver carbonate	low	1	0
jaw	low	1	0
cytochrome c-t	low	1	0
endothelin-1	low	1	0
phosphatidylcholines	low	1	0
bucladesine	low	1	0
resolvin d1	low	1	0
interleukin-8	low	4	0
pr-957	low	1	0
dimethylaminomicheliolide	low	1	0
heparitin sulfate	medium	1	1
minocycline	low	1	0
warfarin	low	2	0
hirudin	low	1	0
lewis x antigen	low	1	0
vitamin b 12	low	4	0
cyclosporine	low	2	0
myelin oligodendrocyte glycoprotein (35-55)	low	3	0
apyrase	low	1	0
exudates	low	7	0
acyclovir	low	3	0
levoleucovorin	low	1	0
inosinic acid	low	1	0
neopterin	low	2	0
olanzapine	low	1	0
eye	low	16	0
leptin	low	1	0

Protein Targets (1,415)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Monocarboxylate transporter 4	0	0	0	2
Chain A, 2-oxoglutarate Oxygenase	19	0	0	19
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
chromobox protein homolog 1	18	0	0	18
geminin	42	0	0	42
glycogen synthase kinase-3 alpha	0	0	0	1
D-amino-acid oxidase	0	2	0	2
Casein kinase II subunit alpha	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Proton-coupled amino acid transporter 1	0	8	0	9
D-aspartate oxidase	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP3	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	13	3	19
Glutamate receptor ionotropic, NMDA 2A	0	12	3	18
Glutamate receptor ionotropic, NMDA 2B	0	13	3	19
Glutamate receptor ionotropic, NMDA 2C	0	12	3	18
Glutamate receptor ionotropic, NMDA 2D	0	12	3	18
Glutamate receptor ionotropic, NMDA 3B	0	12	3	18
Glutamate receptor ionotropic, NMDA 3A	0	12	3	18
estrogen nuclear receptor alpha	50	0	0	50
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	0	1	1
Tyrosine-protein kinase Fyn	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
TDP1 protein	40	0	0	40
glucocorticoid receptor [Homo sapiens]	36	0	0	36
estrogen-related nuclear receptor alpha	40	0	0	40
thyroid hormone receptor beta isoform 2	30	0	0	30
lamin isoform A-delta10	33	0	0	33
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	14	0	0	14
Chain B, HADH2 protein	14	0	0	14
Chain A, Ferritin light chain	12	0	0	12
Thymidine kinase	0	1	0	1
thioredoxin reductase	22	0	0	22
phosphopantetheinyl transferase	26	0	0	26
GLS protein	16	0	0	16
Smad3	8	0	0	8
thyroid stimulating hormone receptor	17	0	0	17
EWS/FLI fusion protein	24	0	0	24
arylsulfatase A	11	0	0	11
euchromatic histone-lysine N-methyltransferase 2	45	0	0	45
activating transcription factor 6	12	0	0	12
Histone H2A.x	16	0	0	16
Bloom syndrome protein isoform 1	18	0	0	18
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
Solute carrier family 22 member 1	0	9	0	13
ATP-binding cassette sub-family C member 3	0	27	0	27
Multidrug resistance-associated protein 4	0	27	0	28
Solute carrier family 22 member 6	0	2	0	3
Bile salt export pump	0	6	0	6
Bile salt export pump	0	41	0	41
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	13	1	15
Cytochrome P450 2J2	0	7	0	7
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	1	0	4
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	4
Canalicular multispecific organic anion transporter 1	0	28	0	29
Thymidine kinase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	17	0	0	17
Carbonic anhydrase 1	0	16	0	22
Carbonic anhydrase 2	0	16	2	24
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	4	2	9
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	4
Chain A, Beta-lactamase	12	0	0	12
Luciferase	7	0	0	7
glp-1 receptor, partial	14	0	0	14
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
RAR-related orphan receptor gamma	28	0	0	28
ATAD5 protein, partial	15	0	0	15
Fumarate hydratase	10	0	0	10
GLI family zinc finger 3	32	0	0	32
AR protein	42	0	0	42
caspase 7, apoptosis-related cysteine protease	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	23	0	0	23
progesterone receptor	21	0	0	21
retinoic acid nuclear receptor alpha variant 1	32	0	0	32
retinoid X nuclear receptor alpha	26	0	0	26
farnesoid X nuclear receptor	22	0	0	22
pregnane X nuclear receptor	29	0	0	29
polyprotein	10	0	0	10
67.9K protein	11	0	0	11
peroxisome proliferator activated receptor gamma	23	0	0	23
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
caspase-3	8	0	0	8
IDH1	15	0	0	15
aryl hydrocarbon receptor	16	0	0	16
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	22	0	0	22
v-jun sarcoma virus 17 oncogene homolog (avian)	19	0	0	19
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
cellular tumor antigen p53 isoform a	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
transcriptional regulator ERG isoform 3	6	0	0	6
histone deacetylase 9 isoform 3	1	0	0	1
heat shock protein beta-1	12	0	0	12
mitogen-activated protein kinase 1	9	0	0	9
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
Vif	0	0	0	1
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	17	0	0	17
muscleblind-like protein 1 isoform 1	8	0	0	8
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
neuropeptide S receptor isoform A	5	0	0	5
Voltage-dependent calcium channel gamma-2 subunit	16	0	0	16
Interferon beta	23	0	0	23
Cellular tumor antigen p53	32	0	0	32
Integrin beta-3	7	1	1	9
Integrin alpha-IIb	7	1	1	9
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	16	4	1	21
Fatty-acid amide hydrolase 1	0	3	0	3
Inositol monophosphatase 1	6	0	0	6
ATPase family AAA domain-containing protein 5	16	0	0	16
Ataxin-2	18	0	0	18
Chain A, Cruzipain	6	0	0	6
interleukin 8	5	0	0	5
peroxisome proliferator-activated receptor delta	22	0	0	22
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	21	0	0	21
nuclear factor erythroid 2-related factor 2 isoform 1	29	0	0	29
Cytochrome P450 1A2	0	1	0	2
Cytochrome P450 3A4	0	12	0	14
Cytochrome P450 2D6	0	5	0	6
Cytochrome P450 2C19	0	7	0	8
Nuclear receptor ROR-gamma	7	0	0	7
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	0	8
glucocerebrosidase	6	0	0	6
DNA polymerase kappa isoform 1	16	0	0	16
histone acetyltransferase KAT2A isoform 1	12	0	0	12
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Microtubule-associated protein tau	17	0	0	17
D(1A) dopamine receptor	4	0	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	5	0	0	5
alpha-galactosidase	6	0	0	6
cytochrome P450 2C19 precursor	8	0	0	8
flap endonuclease 1	13	0	0	13
DNA polymerase iota isoform a (long)	20	0	0	20
muscarinic acetylcholine receptor M1	15	0	0	15
lethal factor (plasmid)	8	0	0	8
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
ATP-dependent phosphofructokinase	14	0	0	14
aldehyde dehydrogenase 1 family, member A1	30	0	0	30
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	25	0	0	25
cytochrome P450 2D6	11	0	0	11
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Adenosine receptor A1	0	5	0	6
Adenosine receptor A2a	0	3	0	5
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	6	0	6
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	14	5	3	22
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	2	1	3
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
estrogen receptor 2 (ER beta)	16	0	0	16
Caspase-7	3	0	0	3
thyroid hormone receptor beta isoform a	15	0	0	15
caspase-3	3	0	0	3
Solute carrier organic anion transporter family member 2B1	0	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
ATP-dependent translocase ABCB1	0	8	0	10
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Histone deacetylase 1	0	8	1	9
Histone deacetylase 2	0	8	1	9
Solute carrier organic anion transporter family member 1B3	0	7	0	11
Histone deacetylase 6	0	7	1	8
Solute carrier organic anion transporter family member 1B1	0	6	0	10
acetylcholinesterase	10	0	0	10
thioredoxin glutathione reductase	11	0	0	11
G	15	0	0	15
P53	2	0	0	2
thyroid stimulating hormone receptor	8	0	0	8
peripheral myelin protein 22 isoform 1	5	0	0	5
cytochrome P450 3A4 isoform 1	14	0	0	14
M-phase phosphoprotein 8	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	14	4	2	20
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
Gamma-aminobutyric acid receptor subunit beta-1	14	4	2	20
Gamma-aminobutyric acid receptor subunit delta	14	4	2	20
Gamma-aminobutyric acid receptor subunit gamma-2	14	4	3	21
Gamma-aminobutyric acid receptor subunit alpha-5	14	4	2	20
Gamma-aminobutyric acid receptor subunit alpha-3	14	4	2	20
Gamma-aminobutyric acid receptor subunit gamma-1	14	4	2	20
Gamma-aminobutyric acid receptor subunit alpha-2	14	4	2	20
Gamma-aminobutyric acid receptor subunit alpha-4	14	4	2	20
Gamma-aminobutyric acid receptor subunit gamma-3	14	4	2	20
Gamma-aminobutyric acid receptor subunit alpha-6	14	4	2	20
Gamma-aminobutyric acid receptor subunit beta-3	14	4	2	20
Gamma-aminobutyric acid receptor subunit beta-2	14	4	3	21
GABA theta subunit	14	4	2	20
Inositol hexakisphosphate kinase 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit epsilon	14	4	2	20
Protein-arginine deiminase type-4	0	6	0	6
cytochrome P450 2C9, partial	15	0	0	15
Proteasome subunit beta type-11	0	2	0	2
PPM1D protein	8	0	0	8
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	2	0	2
Cathepsin B	0	2	0	2
Replicase polyprotein 1ab	0	5	1	6
Replicase polyprotein 1ab	0	6	1	7
Aromatase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit beta type-1	0	3	0	5
Proteasome subunit alpha type-1	0	2	0	2
Proteasome subunit alpha type-2	0	2	0	2
Proteasome subunit alpha type-3	0	2	0	2
Proteasome subunit alpha type-4	0	2	0	2
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	2	0	2
Proteasome subunit beta type-9	0	2	0	2
Proteasome subunit alpha type-5	0	2	0	2
Proteasome subunit beta type-4	0	2	0	2
Proteasome subunit beta type-6	0	2	0	2
Proteasome subunit beta type-5	0	4	0	6
Proteasome subunit beta type-10	0	2	0	2
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	2	0	2
Proteasome subunit beta type-2	0	3	0	5
Proteasome subunit alpha type-6	0	2	0	2
Proteasome subunit alpha-type 8	0	2	0	2
Proteasome subunit beta type-7	0	2	0	2
Gamma-secretase subunit PEN-2	0	1	0	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
USP1 protein, partial	20	0	0	20
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	3	0	0	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	13	0	0	13
apical membrane antigen 1, AMA1	9	0	0	9
nonstructural protein 1	0	2	0	2
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Histone deacetylase 3	0	7	1	8
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	4	0	7
Prothrombin	0	2	2	5
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	4	0	6
Neutrophil elastase	0	3	0	3
Cathepsin G	0	3	0	3
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Carbonic anhydrase 4	0	9	0	12
Carbonic anhydrase 6	0	5	0	8
Chymase	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	4	1	8
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	4	0	7
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	4	0	7
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	3	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	10	0	11
Histone deacetylase 8	0	6	1	7
Carbonic anhydrase 14	0	4	0	7
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	0	6
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
relaxin receptor 1 isoform 1	2	0	0	2
relaxin receptor 2 isoform 1	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	0	2	2
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
DNA polymerase beta	5	0	0	5
nuclear receptor ROR-gamma isoform 1	15	0	0	15
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	1	0	1
Cholinesterase	0	3	0	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	9	0	9
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	2	1	4
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	2	0	3
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	4	0	4
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Kappa-type opioid receptor	0	2	1	4
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	3	0	3
Vitamin D3 receptor A	0	0	2	2
Vpr	2	0	0	2
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	5
Cytochrome P450 2B6	0	0	1	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Carbonic anhydrase	0	6	0	7
endonuclease IV	7	0	0	7
huntingtin isoform 2	6	0	0	6
Glutathione reductase, mitochondrial	0	5	0	5
Alpha-synuclein	3	0	0	3
Glutathione reductase	0	1	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	2	0	4
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	4	0	5
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	4	0	5
Nuclear receptor corepressor 1	0	2	0	2
Nicotinamide phosphoribosyltransferase	0	1	0	1
Histone deacetylase 4	0	5	1	6
Histone deacetylase 7	0	5	1	6
Polyamine deacetylase HDAC10	0	3	1	4
Histone deacetylase 11	0	4	1	5
Histone deacetylase 9	0	4	1	5
Histone deacetylase 5	0	5	1	6
Nuclear receptor corepressor 2	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	1	0	2
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	3	0	3
Alpha-ketoglutarate-dependent dioxygenase FTO	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
tyrosine-protein kinase Yes	2	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Deoxycytidine kinase	0	0	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
mu opioid receptor, partial	0	0	1	1
15-lipoxygenase, partial	6	0	0	6
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
regulator of G-protein signaling 4	10	0	0	10
nonstructural protein 1	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
LAP4	0	0	1	1
MEP2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Amyloid-beta precursor protein	1	5	0	6
Botulinum neurotoxin type A	0	1	0	1
Spike glycoprotein	0	1	0	1
Alpha-1B adrenergic receptor	0	2	1	3
Catechol O-methyltransferase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
TAR DNA-binding protein 43	10	1	0	11
Beta-galactosidase	0	0	1	1
Carbonic anhydrase 13	0	2	0	5
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
heat shock protein 90, putative	0	0	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Fatty acid-binding protein, heart	0	3	0	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
5-hydroxytryptamine receptor 2C	0	6	0	7
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	9	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	2	6
Gamma-aminobutyric acid receptor subunit beta-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	2	6
D	0	2	0	2
5-hydroxytryptamine receptor 1A	0	5	1	6
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent noradrenaline transporter	0	10	0	10
Sodium-dependent dopamine transporter	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-3	0	4	2	6
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	5	0	5
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Sodium-dependent serotonin transporter	0	10	1	11
Sodium-dependent serotonin transporter	0	5	0	6
5-hydroxytryptamine receptor 7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	2	5
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	3	0	3
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	2	5
D(2) dopamine receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Sodium-dependent dopamine transporter	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Leukotriene B4 receptor 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	2	5
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
5-hydroxytryptamine receptor 3B	0	3	0	3
Leukotriene B4 receptor 2	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Transporter	0	5	0	5
pregnane X receptor	4	0	0	4
GALC protein	6	0	0	6
Thrombopoietin	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
Solute carrier family 22 member 3	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	2	2	4
Androgen receptor	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
dopamine D1 receptor	5	0	0	5
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	1	0	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Muscarinic acetylcholine receptor M2	0	4	0	4
Cytochrome P450 2D3	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	7	1	8
Cytochrome P450 2D4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Kelch-like ECH-associated protein 1	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 1A9	0	0	0	4
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	6
UDP-glucuronosyltransferase 1A7	0	0	0	2
Endothelin-1 receptor	0	1	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	2	0	2
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	2	1	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
DNA topoisomerase 2	0	0	0	2
ATP-dependent translocase ABCB1	0	2	0	2
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	9
Tubulin beta-2B chain	0	1	0	1
Integrase	0	3	0	3
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(2) dopamine receptor	0	5	0	5
D(4) dopamine receptor	0	4	0	4
Delta-type opioid receptor	0	3	0	3
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	2	0	2
Histamine H1 receptor	0	3	1	4
Mu-type opioid receptor	0	2	1	3
D(3) dopamine receptor	0	4	0	4
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Sphingosine 1-phosphate receptor 1	0	1	2	3
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	1	0	2
Sphingosine kinase 1	0	1	0	2
Coagulation factor X	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Glutamate receptor 1	0	4	1	5
Glutamate receptor 3	0	4	1	5
Glutamate receptor 4	0	4	1	5
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	3	1	4
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	3	0	3
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate racemase	0	0	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Fatty acid-binding protein, liver	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cannabinoid receptor 2	0	1	1	2
Cannabinoid receptor 2	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Pancreatic alpha-amylase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
High mobility group protein B1	0	0	3	3
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	1	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	1	2
Spike glycoprotein	12	0	1	13
High mobility group protein B1	0	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 2	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	2	0	3
Solute carrier organic anion transporter family member 1B2	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	3	0	4
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Muscarinic acetylcholine receptor M2	0	7	0	7
Muscarinic acetylcholine receptor M4	0	7	0	7
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	3	0	3
Replicase polyprotein 1a	0	2	1	3
Replicase polyprotein 1ab	0	0	1	1
Muscarinic acetylcholine receptor M1	0	6	2	9
Alpha-2B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
Muscarinic acetylcholine receptor M3	0	5	0	5
Alpha-1D adrenergic receptor	0	4	0	4
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	1	3
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
Chain A, Hypoxanthine Phosphoribosyltransferase	0	1	0	1
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE	0	1	0	1
Chain A, hypoxanthine phosphoribosyltransferase	0	0	1	1
Chain A, hypoxanthine phosphoribosyltransferase	0	0	1	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	2
Inosine-5'-monophosphate dehydrogenase	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	3	0	4
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	4
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	1	4
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Dual specificity protein phosphatase 3	0	1	0	1
Fatty acid-binding protein 5	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Free fatty acid receptor 4	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
Large neutral amino acids transporter small subunit 1	0	1	0	1
Acetylcholinesterase	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Cholinesterase	0	2	0	2
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	2	0	0	2
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
DNA polymerase eta isoform 1	6	0	0	6
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	6	0	7
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	4	2	6
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	5	0	6
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	3
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	2	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Translocator protein	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	2	0	4
UDP-glucuronosyltransferase 2B10	0	2	0	2
Albumin	0	1	2	3
Stromelysin-1	0	2	1	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
WRN	2	0	0	2
DNA polymerase III, partial	1	0	0	1
LANA	0	0	0	1
Parkin	2	0	0	2
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
phospholipase A2, group III	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
interferon gamma precursor	0	0	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
protein AF-9 isoform a	0	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	1	2
5-hydroxytryptamine receptor 4	0	6	0	6
Glycoprotein hormones alpha chain	2	0	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Proto-oncogene tyrosine-protein kinase ROS	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Angiotensin-converting enzyme	0	3	0	3
Casein kinase II subunit alpha'	0	1	0	1
5-hydroxytryptamine receptor 2C	0	8	0	8
Histamine H2 receptor	6	0	0	6
Guanine nucleotide-binding protein G	3	0	0	3
Casein kinase II subunit beta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	1	2
Tyrosine-protein kinase BTK	0	1	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	1	2
Nuclear receptor subfamily 3 group C member 3	0	3	0	3
Multidrug and toxin extrusion protein 2	0	1	0	1
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Lysine-specific demethylase 4C	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Polyphenol oxidase 2	0	2	0	3
Cholesteryl ester transfer protein	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
Hydroxycarboxylic acid receptor 2	0	1	1	2
Sodium/iodide cotransporter	0	1	0	1
5-hydroxytryptamine receptor 3E	0	3	0	3
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
5-hydroxytryptamine receptor 3B	0	3	0	3
5-hydroxytryptamine receptor 1A	0	5	2	7
D(3) dopamine receptor	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	5	0	5
D(4) dopamine receptor	0	1	0	1
Histamine H1 receptor	0	2	1	3
5-hydroxytryptamine receptor 7	0	2	0	2
Alpha-1A adrenergic receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
5-hydroxytryptamine receptor 3D	0	3	0	3
5-hydroxytryptamine receptor 3C	0	3	0	3
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
serine/threonine-protein kinase PLK1	5	0	0	5
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	2	0	2
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Transmembrane prolyl 4-hydroxylase	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
cytochrome P450 2C9 precursor	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 1D	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Kallikrein-1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Chymotrypsin-like elastase family member 2A	0	1	0	1
Myeloblastin	0	1	0	1
Trypsin-3	0	1	0	1
Neutrophil elastase	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
streptokinase A precursor	0	0	2	2
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	2	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	2	2
Protein kinase C eta type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protease	0	2	1	3
Carboxypeptidase M	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
BRCA1	1	0	0	1
RAD51	0	1	0	1
Cocaine esterase	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Polycomb protein EED	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Polycomb protein SUZ12	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Protease	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	2
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Chain A, Neuraminidase	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Chain A, NEURAMINIDASE	0	1	0	1
Chain A, Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Sialidase-1	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	1	1	2
Acyl-CoA desaturase 1	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase A	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	2	0	2
Sialidase-1	0	1	0	1
Sialidase-3	0	2	0	2
Sialidase-2	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(11)

Research Excerpts

Overview

Context

Treatment

Research

Studies (592)

Protein Targets (1,415)

Devic Disease

Synonyms(11)

Research Excerpts

Overview

Context

Treatment

Research

Studies (592)

Drugs Studied (204)

Protein Targets (1,415)