Page last updated: 2024-08-05 12:30:00

vitamin E

Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.

ChEBI ID: 33234

Members (7)

MemberDefinitionRole
beta-tocopherolA tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts.beta-tocopherol
delta-tocopherolA tocopherol in which the chroman-6-ol core is substituted by a methyl group at position 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.delta-tocopherol
gamma-tocopherolA tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.gamma-tocopherol
gamma-tocotrienolA tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. A vitamin E family member that has potent anti-cancer properties against a wide-range of cancers.gamma-tocotrienol
tocotrienol, alphaA tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a farnesyl chain at position 2. It has been found in palm oil derived from Elaeis guineensis.alpha-tocotrienol
tocotrienol, betaA tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat.beta-tocotrienol
tocotrienol, deltaA tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2.delta-tocotrienol

Research

Studies (850)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199018 (2.12)18.7374
1990's23 (2.71)18.2507
2000's335 (39.41)29.6817
2010's379 (44.59)24.3611
2020's95 (11.18)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials94 (9.40%)5.53%
Reviews38 (3.80%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other868 (86.80%)84.16%