| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Kynureninase | 0 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| GLS protein | 2 | 0 | 0 | 2 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 4 | 0 | 0 | 4 |
| AR protein | 5 | 0 | 0 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| glucocerebrosidase | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 4 | 0 | 0 | 4 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| mitogen-activated protein kinase 1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| transient receptor potential cation channel subfamily V member 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 5 | 0 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Transient receptor potential cation channel subfamily V member 1 | 0 | 2 | 1 | 3 |
| Lysine-specific histone demethylase 1A | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| NADH-ubiquinone oxidoreductase chain 1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Cannabinoid receptor 1 | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Cannabinoid receptor 2 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| D(2) dopamine receptor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 1 | 0 | 1 | 0 | 1 |
| Corticotropin-releasing factor receptor 2 | 0 | 1 | 0 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | 0 | 2 | 1 | 4 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Transient receptor potential cation channel subfamily V member 4 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| Transient receptor potential cation channel subfamily V member 2 | 0 | 0 | 1 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| IDH1 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| geminin | 5 | 0 | 0 | 5 |
| Vpr | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Albumin | 0 | 0 | 1 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 3 |
| Cytochrome P450 2B6 | 0 | 0 | 1 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Sodium channel protein type 9 subunit alpha | 0 | 2 | 0 | 2 |
| Frizzled-8 | 0 | 0 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| P2X purinoceptor 4 | 0 | 1 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
| DNA polymerase beta | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Translocator protein | 0 | 1 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Glutamate receptor 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor 4 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, kainate 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, kainate 4 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, kainate 5 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 2 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 2 | 1 | 4 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Receptor-type tyrosine-protein phosphatase beta | 0 | 0 | 0 | 1 |
| Low molecular weight phosphotyrosine protein phosphatase | 0 | 1 | 0 | 1 |
| P2X purinoceptor 1 | 0 | 0 | 1 | 1 |
| P2X purinoceptor 1 | 0 | 1 | 0 | 1 |
| P2X purinoceptor 4 | 0 | 0 | 1 | 1 |
| Trans-sialidase | 0 | 1 | 0 | 1 |
| Trans-sialidase | 0 | 1 | 0 | 1 |
| P2X purinoceptor 2 | 0 | 0 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| Cocaine esterase | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
| Tissue factor | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1-6 | 0 | 0 | 0 | 1 |
| Liver carboxylesterase 1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 4 | 0 | 2 | 0 | 2 |
| Histone deacetylase 1 | 0 | 2 | 0 | 2 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B7 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 7 | 0 | 2 | 0 | 2 |
| Histone deacetylase 2 | 0 | 2 | 0 | 2 |
| Polyamine deacetylase HDAC10 | 0 | 2 | 0 | 2 |
| Histone deacetylase 11 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Histone deacetylase 8 | 0 | 2 | 0 | 2 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
| Histone deacetylase 6 | 0 | 2 | 0 | 2 |
| Histone deacetylase 9 | 0 | 2 | 0 | 2 |
| Histone deacetylase 5 | 0 | 2 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | 0 | 1 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 1 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| glycogen synthase kinase-3 alpha | 0 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Estrogen receptor beta | 0 | 0 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |