Page last updated: 2024-09-27

Hyperlipoproteinemia Type IV

A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits.

Synonyms(1)

Synonym
Hyperlipoproteinemia Type IV

Research

Studies (434)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990341 (78.57)23.3326
1990's56 (12.90)12.5806
2000's27 (6.22)18.1394
2010's8 (1.84)28.8240
2020's2 (0.46)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetic acid0low10
carnitine0medium51
glycine0low10
glycerol0low60
hydrogen carbonate0low10
inositol0low20
niacin0medium71
palmitic acid0low10
uric acid0medium102
1-anilino-8-naphthalenesulfonate0medium102
theophylline0low10
atenolol0low10
benzamidine0medium11
buformin0low10
cimetidine0low10
ciprofibrate0low10
clofibrate0medium529
clofibric acid0medium255
fenofibrate0medium236
gemfibrozil0medium2611
inositol niacinate0low10
metformin0low20
niceritrol0low10
prazosin0low10
probucol0medium92
propranolol0low10
sulfinpyrazone0low10
ticlopidine0low10
sorbitol0low10
thyroxine0low10
oxandrolone0low10
triiodothyronine0low50
biguanides0low10
serine0low10
aspartic acid0low10
sucrose0low30
ethinyl estradiol0low10
adenosine diphosphate0low30
edetic acid0low10
cysteamine0low10
leucine0low20
asparagine0low10
nicotinyl alcohol0low10
phenformin0low10
framycetin0low30
dextrothyroxine0low20
quinazolines0low10
pyrazines0medium64
nitroblue tetrazolium0low10
xanthinol niacinate0low20
fluorobenzenes0low10
chenodeoxycholic acid0medium81
d-alpha tocopherol0low50
tocopherols0low20
tiadenol0medium21
cupric chloride0low10
tricalcium phosphate0low10
trolamine salicylate0low30
phenyl acetate0low40
ursodeoxycholic acid0low10
glutamic acid0low10
bezafibrate0medium3310
etofylline clofibrate0medium42
beclobrate0medium11
lovastatin0medium52
simvastatin0medium11
adenosine0low10
colestipol0medium51
glucose, (beta-d)-isomer0low10
mevastatin0low10
fenofibric acid0medium62
etofibrate0medium41
sultosilic acid0low10
plafibride0medium42
pirinixil0medium11
tyloxapol0low10
coenzyme a0medium11
fibrinogen0medium62
homocysteine0low20
cobalt0low10
vitamin b 60low20
valerates0medium85
thromboxanes0low10
ci 9240medium11
dansyl phosphatidylethanolamine0low10
cholic acid0low50
deoxycholic acid0low10
cortisone0low10
elastin0low10
pantetheine0low20
arachidonic acid0low10
retinol0low40
oleic acid0low10
eicosapentaenoic acid0medium104
prostaglandin d20low10
afimoxifene0low10
pantethine0low20
gamma-sitosterol0low10
squalene0low10
arginine vasopressin0low10
D-fructopyranose0low30
thioacetamide0medium11
tamoxifen0low20
cobaltous chloride0low10
glucitol hexanicotinate0low10
cytellin0low10
24,25-epoxycholesterol0low10
bilirubin0low10
linoleic acid0low10
retinol palmitate0low20
gamma-linolenic acid0low10
cynarine0low10
thromboxane b20low30
acipimox0medium54
deamino arginine vasopressin0low10
lysophosphatidylcholines0low10
triolein0low10
glucuronyl glucosamine glycan sulfate0medium52
omacor0low20
empagliflozin0low10
sepharose0low10
glucagon0low90
c-peptide0low10
cellulose0low10
phosphatidylcholines0medium101
jsh 230low10
s-adenosylmethionine0low10
glycolipids0low20
ascorbic acid0low30
oxytetracycline, anhydrous0low10
vitamin b 120low20
norgestrel0low10
promega0medium32
cyclic gmp0low10
sapropterin0low10
folic acid0low20
allopurinol0low10
cholestyramine resin0low60
concanavalin a0low10

Protein Targets (1,023)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A9009
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase2002
thioredoxin reductase150015
USP1 protein, partial280028
TDP1 protein340034
vitamin D3 receptor isoform VDRA140014
importin subunit beta-1 isoform 14004
flap endonuclease 17007
serine/threonine-protein kinase PLK16006
snurportin-14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase eta isoform 14004
DNA polymerase iota isoform a (long)8008
urokinase-type plasminogen activator precursor6006
plasminogen precursor6006
urokinase plasminogen activator surface receptor precursor6006
geminin310031
DNA polymerase kappa isoform 1130013
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0101
Transthyretin0226
Fatty acid-binding protein, intestinal0628
Fatty acid-binding protein, adipocyte08311
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20112
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G6006
Fatty acid-binding protein 50527
Fatty acid-binding protein 50022
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
Oxysterols receptor LXR-beta0011
Oxysterols receptor LXR-alpha0011
estrogen nuclear receptor alpha440044
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Tyrosine-protein kinase Lck0112
Tyrosine-protein kinase Fyn0112
Fibrinogen C domain-containing protein 10101
Fumarate hydratase5005
AR protein370037
EWS/FLI fusion protein140014
polyprotein5005
histone acetyltransferase KAT2A isoform 1140014
ATP-binding cassette sub-family C member 3020020
Multidrug resistance-associated protein 4020022
Bile salt export pump032032
Cellular tumor antigen p53260026
Hydroxycarboxylic acid receptor 20224
Canalicular multispecific organic anion transporter 1017017
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 4130013
glucocorticoid receptor [Homo sapiens]210021
retinoid X nuclear receptor alpha190019
NPYLR7B0011
arylsulfatase A9009
IDH1100010
Histone H2A.x9009
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 16006
nuclear receptor ROR-gamma isoform 1140014
peripheral myelin protein 22150015
survival motor neuron protein isoform d9009
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70022
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit9009
Rap guanine nucleotide exchange factor 36006
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0303
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20202
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0225
Platelet-derived growth factor receptor beta0001
Adenosine receptor A3010314
Heat shock 70 kDa protein 1A 0213
Heat shock cognate 71 kDa protein0022
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0113
Glutamate receptor 292112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10416
Adenosine receptor A30202
Adenosine receptor A2a08616
Adenosine receptor A2b0114
Adenosine receptor A2b0214
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A1010316
Adenosine receptor A2a0215
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0405
Adenosine receptor A10112
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0405
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0405
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0405
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Endoplasmic reticulum chaperone BiP0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor0527
Delta-type opioid receptor0325
Kappa-type opioid receptor0527
Endoplasmin0112
P2Y purinoceptor 20011
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 14004
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
P2Y purinoceptor 110011
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
P2X purinoceptor 20011
Chain A, Beta-lactamase140014
Chain A, 2-oxoglutarate Oxygenase9009
Chain A, Ferritin light chain110011
acetylcholinesterase100010
glp-1 receptor, partial7007
pregnane X receptor5005
phosphopantetheinyl transferase170017
hypoxia-inducible factor 1 alpha subunit9009
RAR-related orphan receptor gamma230023
SMAD family member 28008
SMAD family member 38008
GLI family zinc finger 3190019
Microtubule-associated protein tau160016
Smad36006
apical membrane antigen 1, AMA15005
caspase 7, apoptosis-related cysteine protease6006
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3140014
progesterone receptor120012
nonstructural protein 12002
retinoic acid nuclear receptor alpha variant 1240024
estrogen-related nuclear receptor alpha250025
farnesoid X nuclear receptor150015
pregnane X nuclear receptor190019
67.9K protein5005
glucocerebrosidase5005
bromodomain adjacent to zinc finger domain 2B7007
peroxisome proliferator-activated receptor delta180018
peroxisome proliferator activated receptor gamma170017
vitamin D (1,25- dihydroxyvitamin D3) receptor220022
caspase-36006
euchromatic histone-lysine N-methyltransferase 2270027
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
thyroid stimulating hormone receptor9009
activating transcription factor 69009
thyrotropin-releasing hormone receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a150015
v-jun sarcoma virus 17 oncogene homolog (avian)150015
Caspase-73003
thyroid hormone receptor beta isoform a100010
caspase-33003
thyroid hormone receptor beta isoform 2220022
heat shock protein beta-1130013
ubiquitin-conjugating enzyme E2 N0202
nuclear factor NF-kappa-B p105 subunit isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 1270027
lamin isoform A-delta10280028
neuropeptide S receptor isoform A4004
Phospholipase D20101
Estrogen receptor0529
Aromatase0505
Estrogen-related receptor gamma0213
Phospholipase D10202
Estrogen receptor beta0426
ATPase family AAA domain-containing protein 55005
Ataxin-26006
interleukin 86006
thyroid stimulating hormone receptor130013
Bloom syndrome protein isoform 16006
transcriptional regulator ERG isoform 34004
ras-related protein Rab-9A3003
Polyphenol oxidase 20303
Hypoxanthine-guanine phosphoribosyltransferase0001
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Xanthine dehydrogenase/oxidase0303
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 43120012
Shiga toxin subunit A0101
Histamine H3 receptor0101
ATAD5 protein, partial6006
chromobox protein homolog 1190019
nuclear factor erythroid 2-related factor 2 isoform 27007
Cytochrome P450 2C9 0617
Cytochrome P450 2J20505
Nicotinate phosphoribosyltransferase0202
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0022
Chain A, SERUM ALBUMIN0022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE120012
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Cruzipain5005
15-lipoxygenase, partial4004
thioredoxin glutathione reductase8008
aldehyde dehydrogenase 1 family, member A1180018
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
cellular tumor antigen p53 isoform a3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
lethal(3)malignant brain tumor-like protein 1 isoform I3003
cytochrome P450 3A4 isoform 1150015
DNA dC->dU-editing enzyme APOBEC-3G isoform 13003
caspase-1 isoform alpha precursor2002
Fatty-acid amide hydrolase 10202
Gamma-aminobutyric acid receptor subunit pi151319
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Prostaglandin G/H synthase 1 0405
Trypsin0505
Coagulation factor VII0606
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Tissue factor0606
Gamma-aminobutyric acid receptor subunit beta-1151319
Gamma-aminobutyric acid receptor subunit delta151319
Gamma-aminobutyric acid receptor subunit gamma-2151319
Gamma-aminobutyric acid receptor subunit alpha-5151319
Gamma-aminobutyric acid receptor subunit alpha-3151319
Gamma-aminobutyric acid receptor subunit gamma-1151319
Gamma-aminobutyric acid receptor subunit alpha-2151319
Gamma-aminobutyric acid receptor subunit alpha-4151319
Gamma-aminobutyric acid receptor subunit gamma-3151319
Gamma-aminobutyric acid receptor subunit alpha-6151319
Prostaglandin G/H synthase 20315
Nuclear receptor subfamily 4 group A member 20044
Histamine H2 receptor82111
10 kDa heat shock protein, mitochondrial0101
Calmodulin 0001
Gamma-aminobutyric acid receptor subunit alpha-1151319
Gamma-aminobutyric acid receptor subunit beta-3151319
Gamma-aminobutyric acid receptor subunit beta-2151319
Disintegrin and metalloproteinase domain-containing protein 174004
Prostaglandin G/H synthase 20405
Solute carrier organic anion transporter family member 2A10103
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0303
60 kDa chaperonin 0101
10 kDa chaperonin 0101
GABA theta subunit151319
Gamma-aminobutyric acid receptor subunit epsilon151319
Solute carrier organic anion transporter family member 1B30507
Cytosolic phospholipase A2 gamma0101
Transient receptor potential cation channel subfamily V member 20303
Solute carrier organic anion transporter family member 1B107010
Translocator protein0011
Vasopressin V2 receptor0326
Oxytocin receptor0123
Vasopressin V1a receptor0022
Vasopressin V1a receptor0336
Vasopressin V1b receptor0224
Vasopressin V2 receptor0011
Vasopressin V1b receptor0113
Translocator protein0203
Oxytocin receptor0101
Vasopressin V2 receptor 0224
Chain A, Hyaluronidase, phage associated0101
cytochrome P450 family 3 subfamily A polypeptide 4200020
lethal factor (plasmid)7007
Pancreatic alpha-amylase0202
Albumin0101
Urease0202
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor06412
Spike glycoprotein90110
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Carbonic anhydrase 10205
Carbonic anhydrase 20317
Neutral amino acid transporter A0202
Neutral amino acid transporter B(0)0202
Carbonic anhydrase-like protein, putative0003
Amino acid transporter0202
cytochrome P450 2C19 precursor5005
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0102
Glutamate receptor ionotropic, NMDA 1 0538
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 0538
Glutamate receptor ionotropic, NMDA 2B0538
Glutamate receptor ionotropic, NMDA 2C0538
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Glutamate receptor ionotropic, NMDA 2D0538
Glutamate receptor ionotropic, NMDA 3B0538
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0538
Beta-1 adrenergic receptor 0124
D(1A) dopamine receptor5005
Fatty acid-binding protein, liver07310
Beta-2 adrenergic receptor0426
Beta-1 adrenergic receptor0628
Beta-3 adrenergic receptor0628
5-hydroxytryptamine receptor 1A0629
Alpha-1D adrenergic receptor05210
Alpha-1A adrenergic receptor04312
Alpha-1B adrenergic receptor0328
Beta-2 adrenergic receptor0124
ATP-dependent phosphofructokinase100010
Chain A, TRYPSIN0101
Chain H, Thrombin heavy chain0101
Chain H, Thrombin heavy chain0101
Chain A, PROTEIN (TRYPSIN)0101
Chain A, PROTEIN (TRYPSIN)0101
Chain A, PROTEIN (TRYPSIN)0101
Chain A, PROTEIN (TRYPSIN)0101
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)0101
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)0101
Chain B, PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)0101
Chain A, PROTEIN (TRYPSIN)0101
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, TRYPSIN IVA0101
Chain A, trypsin II, anionic0101
Chain A, Trypsin II, anionic0101
Chain A, Trypsin II, anionic0101
Chain T, Trypsin II, anionic0101
Chain A, trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain T, Trypsin0101
Chain A, PROTEIN (TRYPSIN)0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
pyruvate kinase PKM isoform b1001
Prothrombin0134
Prothrombin 0101
Coagulation factor X0101
Coagulation factor X0101
Urokinase-type plasminogen activator0101
Tissue-type plasminogen activator0101
Cationic trypsin0101
Acrosin0101
Ornithine decarboxylase1001
Aldehyde oxidase0204
Suppressor of tumorigenicity 14 protein0101
Luciferase9009
G140014
Glutamate receptor ionotropic, NMDA 2D0134
Glutamate receptor ionotropic, NMDA 3B0134
Bile salt export pump0404
5-hydroxytryptamine receptor 40639
Interferon beta160016
HLA class I histocompatibility antigen, B alpha chain 140014
Muscarinic acetylcholine receptor M10033
Muscarinic acetylcholine receptor M30033
Muscarinic acetylcholine receptor M40033
Muscarinic acetylcholine receptor M50033
Muscarinic acetylcholine receptor M20033
Peroxisome proliferator-activated receptor alpha0055
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor gamma021113
Peroxisome proliferator-activated receptor gamma0055
Peroxisome proliferator-activated receptor delta0034
Glutamate receptor ionotropic, NMDA 10134
Peroxisome proliferator-activated receptor alpha53917
Glutamate receptor ionotropic, NMDA 2A0134
Glutamate receptor ionotropic, NMDA 2B0134
Glutamate receptor ionotropic, NMDA 2C0134
Glutamate receptor ionotropic, NMDA 3A0134
Inositol hexakisphosphate kinase 1140014
cytochrome P450 2C9, partial140014
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Caspase-71001
cytochrome P450 2D68008
Solute carrier family 22 member 10205
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Alpha-2A adrenergic receptor07413
Vitamin D3 receptor0448
Alpha-2C adrenergic receptor05411
Retinoic acid receptor RXR-alpha0011
Ileal sodium/bile acid cotransporter0303
Bile acid receptor0011
G-protein coupled bile acid receptor 10145
Bile acid receptor0145
Ubiquitin carboxyl-terminal hydrolase 20202
Phospholipase A20011
G-protein coupled bile acid receptor 10101
alpha-galactosidase4004
M-phase phosphoprotein 86006
muscarinic acetylcholine receptor M15005
Solute carrier family 22 member 10101
Solute carrier family 22 member 20607
Solute carrier family 22 member 1 0606
Solute carrier family 22 member 60202
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10719
Cytochrome P450 3A40404
Cytochrome P450 2D60404
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10101
Histamine H2 receptor0404
Histamine H1 receptor0011
Potassium-transporting ATPase subunit beta0101
Solute carrier family 22 member 60102
Multidrug and toxin extrusion protein 20303
Solute carrier family 22 member 80304
Multidrug and toxin extrusion protein 10606
Histamine H4 receptor0101
Solute carrier family 22 member 110101
Solute carrier family 22 member 20202
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
aryl hydrocarbon receptor7007
Peroxisome proliferator-activated receptor alpha0033
GALC protein1001
peripheral myelin protein 22 isoform 13003
potassium voltage-gated channel subfamily H member 2 isoform d6006
cytochrome P450 2D6 isoform 14004
Neuronal acetylcholine receptor subunit alpha-70011
Histone acetyltransferase p3000101
Histone acetyltransferase KAT2B0101
Histone acetyltransferase KAT50101
N-alpha-acetyltransferase 500011
endonuclease IV2002
dopamine D1 receptor1001
GLS protein6006
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor0415
Sex hormone-binding globulin0022
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Potassium voltage-gated channel subfamily A member 10011
Phosphodiesterase 0303
Multidrug resistance-associated protein 50102
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
Integrase 0101
Histone-lysine N-methyltransferase EHMT20101
Glutaminyl-peptide cyclotransferase0101
Histone-lysine N-methyltransferase EHMT10101
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
cytochrome P450 2C9 precursor5005
Thyroid hormone receptor beta0303
Solute carrier organic anion transporter family member 1C10202
Eyes absent homolog 20101
Amyloid-beta precursor protein0404
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
Cytochrome P450 1A20202
Retinoic acid receptor RXR-alpha0123
Oxoeicosanoid receptor 10101
Sodium/glucose cotransporter 10011
Sodium/glucose cotransporter 20112
PPM1D protein2002
lysosomal alpha-glucosidase preproprotein5005
Vpr1001
Cytochrome P450 2B10101
Aldo-keto reductase family 1 member B10808
Neuronal acetylcholine receptor subunit alpha-43003
Neuronal acetylcholine receptor subunit beta-23003
Polyunsaturated fatty acid lipoxygenase ALOX150101
Androgen receptor0606
Alpha-1B adrenergic receptor09211
Cytochrome P450 2B60404
UDP-glucuronosyltransferase 1A1 0203
Sodium-dependent noradrenaline transporter 0808
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sodium-dependent serotonin transporter0606
Alpha-1A adrenergic receptor09211
Sulfotransferase 1A10214
Nuclear receptor ROR-gamma5005
Sodium-dependent dopamine transporter 0808
Nuclear receptor subfamily 1 group I member 3 0101
Sodium-dependent serotonin transporter0011
serine-protein kinase ATM isoform a2002
serine/threonine-protein kinase mTOR isoform 14004
Fatty acid-binding protein, liver0213
Acetylcholinesterase0101
Cruzipain0101
5-hydroxytryptamine receptor 2A0617
5-hydroxytryptamine receptor 2C0617
D(3) dopamine receptor0505
Sigma non-opioid intracellular receptor 10022
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Prostaglandin G/H synthase 10404
Chloride channel isoform 1 0011
Chain A, Dihydrofolate reductase0011
DNA polymerase beta2002
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Alpha-synuclein3104
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30103
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Menin0011
Lecithin retinol acyltransferase0101
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Lethal factor0101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
WRN2002
Caspase 6, apoptosis-related cysteine peptidase0001
isocitrate dehydrogenase 1, partial3003
Free fatty acid receptor 10022
histone deacetylase 9 isoform 32002
muscleblind-like protein 1 isoform 13003
Cytochrome P450 2C80303
Cannabinoid receptor 20011
Guanylate cyclase soluble subunit alpha-10011
Guanylate cyclase soluble subunit beta-10011
CDGSH iron-sulfur domain-containing protein 10404
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Integrin beta-32013
Integrin alpha-IIb2013
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10202
Proton-coupled amino acid transporter 10304
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Carbonic anhydrase 40101
Carbonic anhydrase0101
Carbonic anhydrase 150101
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Sodium/myo-inositol cotransporter 20101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0303
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Sterol O-acyltransferase 10202
Fatty acid-binding protein, heart0202
Seed linoleate 13S-lipoxygenase-10202
Tyrosine-protein phosphatase non-receptor type 70101
Sterol O-acyltransferase 10202
Aldo-keto reductase family 1 member C30101
Dual specificity protein phosphatase 30101
Free fatty acid receptor 40011
Chain A, Antigen Cd11a (p180)0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
PINK13003
Parkin3003
nuclear receptor subfamily 1, group I, member 24004
bcl-2-related protein A10101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0404
Integrin beta-20101
Intercellular adhesion molecule 10101
Neutrophil elastase0101
Insulin receptor 0303
Integrin alpha-L0112
Substance-K receptor0404
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0404
Histone deacetylase 10101
Rap guanine nucleotide exchange factor 42002
Histone deacetylase 20101
Acyl-CoA:cholesterol acyltransferase 0101
Histone deacetylase 60101
Dihydrofolate reductase0202
Dipeptidyl peptidase 40101
huntingtin isoform 21001
D(1A) dopamine receptor3003
Potassium channel subfamily K member 90101
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, BCL-2-RELATED PROTEIN A10011
putative potassium channel subunit0011
bcl-2-like protein 11 isoform 10011
DNA topoisomerase 10101
Protein kinase C alpha type0102
Tyrosine-protein phosphatase non-receptor type 10202
Androgen receptor0303
Valosin-containing protein0101
microphthalmia-associated transcription factor isoform 90101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
Chain A, Fatty acid-binding protein, adipocyte0101
Acetylcholinesterase0202
Toll-like receptor 20101
Carbonic anhydrase 120101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Carbonic anhydrase 90213
Cytochrome P450 2D40101
NPC intracellular cholesterol transporter 1 precursor2002
interferon gamma precursor0002
Alpha-1A adrenergic receptor0112
Solute carrier family 22 member 30101
Beta-casein0101
Interstitial collagenase0101
5-hydroxytryptamine receptor 1A0303
5-hydroxytryptamine receptor 2C0202
Angiotensin-converting enzyme0404
Matrix metalloproteinase-90101
5-hydroxytryptamine receptor 2A0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Alpha-2A adrenergic receptor0101
D0101
Alpha-2B adrenergic receptor0123
Alpha-mannosidase 2C10011
D(4) dopamine receptor0303
Alpha-2C adrenergic receptor0123
Alpha-2A adrenergic receptor0123
Alpha-1D adrenergic receptor0325
Bromodomain-containing protein 20202
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 1B0505
5-hydroxytryptamine receptor 1D0101
Alpha-2B adrenergic receptor0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Delta-type opioid receptor0101
Type-1 angiotensin II receptor0101
5-hydroxytryptamine receptor 2B0617
5-hydroxytryptamine receptor 70202
D(2) dopamine receptor0202
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Potassium voltage-gated channel subfamily H member 20505
Alpha-2A adrenergic receptor0101
Nuclear receptor subfamily 3 group C member 3 0404
Polyunsaturated fatty acid lipoxygenase ALOX150101
Vascular cell adhesion protein 10101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Albumin0011
Muscarinic acetylcholine receptor M20314
Beta-2 adrenergic receptor0203
Muscarinic acetylcholine receptor M10314
D(2) dopamine receptor0314
Beta-1 adrenergic receptor0214
D(3) dopamine receptor0202
Muscarinic acetylcholine receptor M30314
D(1A) dopamine receptor0314
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Cytochrome P450 2C190303
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
5-hydroxytryptamine receptor 60415
Beta-2 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Sodium/bile acid cotransporter0202
Sigma non-opioid intracellular receptor 10606
Nuclear receptor subfamily 2 group E member 10022
Solute carrier organic anion transporter family member 2A10103
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10001
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Nitric oxide synthase, brain0011
Pyruvate kinase PKM0011
Cholinesterase0101
photoreceptor-specific nuclear receptor0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Sigma non-opioid intracellular receptor 10213
Bifunctional epoxide hydrolase 20101
Squalene monooxygenase 0001
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
polyunsaturated fatty acid lipoxygenase ALOX121001
fMet-Leu-Phe receptor0101
fMet-Leu-Phe receptor0101
Solute carrier family 22 member 120101
Chain A, CES1 protein0101
DNA polymerase III, partial1001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
streptokinase A precursor0011
Transmembrane protease serine 20011
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Progesterone receptor0101
Procathepsin L0011
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
UDP-glucuronosyltransferase 1A40001
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Protein kinase C iota type0101
Melanocortin receptor 30202
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Potassium channel subfamily K member 20011
Renin0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A10202
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Adenylate cyclase type 10001
Chitotriosidase-10101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Endochitinase B10101
Taste receptor type 2 member 380001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50002
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Solute carrier organic anion transporter family member 4C10001
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
M1-family alanyl aminopeptidase0101
Carbonic anhydrase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]