| Assay ID | Title | Year | Journal | Article |
|---|
| AID1312218 | Inhibition of Plasmodium falciparum full length recombinant His-fused Eta-carbonic anhydrase domain preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18
| Anion inhibition profiles of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum. |
| AID598728 | Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 | 2011 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 21, Issue:12
| Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. |
| AID1070021 | Inhibition of Legionella pneumophila carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2014 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 24, Issue:4
| Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID1237475 | Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow method | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. |
| AID1374897 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 10 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM additi | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1461938 | Inhibition of recombinant His6-tagged Francisella tularensis beta-CA (227 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins by stopped-flow CO2 hydration assay | | | |
| AID763569 | Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2013 | Bioorganic & medicinal chemistry, Aug-01, Volume: 21, Issue:15
| Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID1461935 | Inhibition of Burkholderia pseudomallei beta-CA incubated for 15 mins by stopped-flow CO2 hydration assay | | | |
| AID216730 | Cytotoxicity activity against V79 cells | 2003 | Journal of medicinal chemistry, Jul-17, Volume: 46, Issue:15
| Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells. |
| AID763567 | Inhibition of Brucella suis beta carbonic anhydrase-1 at 20 degC by stopped-flow CO2 hydrase assay | 2013 | Bioorganic & medicinal chemistry, Aug-01, Volume: 21, Issue:15
| Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID1235244 | Inhibition of Nostoc commune CA after 15 mins by stopped-flow/Co2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID647373 | Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins measured for 10 to 100 secs by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana. |
| AID758950 | Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules. |
| AID1336558 | Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID763566 | Inhibition of Brucella suis beta carbonic anhydrase-2 at 20 degC by stopped-flow CO2 hydrase assay | 2013 | Bioorganic & medicinal chemistry, Aug-01, Volume: 21, Issue:15
| Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID323921 | Enhancement of HCV RNA replication in OR6 cells after 72 hrs by luciferase reporter assay | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6
| Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture. |
| AID1058395 | Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens. |
| AID763565 | Inhibition of recombinant Trypanosoma cruzi CL Brener alpha carbonic anhydrase expressed in baculovirus infected SF9 cells at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2013 | Bioorganic & medicinal chemistry, Aug-01, Volume: 21, Issue:15
| Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease. |
| AID416958 | Inhibition of human recombinant carbonic anhydrase 1-catalyzed CO2 hydration by stopped flow assay | 2009 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 19, Issue:7
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
| AID730752 | Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID714401 | Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23
| Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense. |
| AID416960 | Inhibition of human recombinant carbonic anhydrase 4-catalyzed CO2 hydration by stopped flow assay | 2009 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 19, Issue:7
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
| AID1336560 | Inhibition of Nostoc commune recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID1235242 | Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID1161930 | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases. |
| AID416962 | Inhibition of mouse recombinant carbonic anhydrase 13-catalyzed CO2 hydration by stopped flow assay | 2009 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 19, Issue:7
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
| AID714400 | Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23
| Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense. |
| AID1070020 | Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | 2014 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 24, Issue:4
| Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID75283 | Glutathione peroxidase activity in V79 cells at 100 uM expressed as fold induction of GPx activity to control value | 2003 | Journal of medicinal chemistry, Jul-17, Volume: 46, Issue:15
| Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells. |
| AID1430528 | Inhibition of Burkholderia pseudomallei recombinant His-tagged carbonic anhydrase beta (256 residues) expressed in Escherichia coli BL21 (DE3) incubated for 15 mins prior to testing by stopped flow CO2 hydration method | | | |
| AID1161951 | Inhibition of Porphyromonas gingivalis gamma-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis. |
| AID758948 | Inhibition of Porphyromonas gingivalis recombinant CA by CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules. |
| AID416959 | Inhibition of human recombinant carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow assay | 2009 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 19, Issue:7
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
| AID1430526 | Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow CO2 hydration method | | | |
| AID552785 | Inhibition of Streptococcus pneumoniae beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives? |
| AID1430527 | Inhibition of Burkholderia pseudomallei recombinant carbonic anhydrase gamma incubated for 15 mins prior to testing by stopped flow CO2 hydration method | | | |
| AID416961 | Inhibition of human recombinant carbonic anhydrase 7-catalyzed CO2 hydration by stopped flow assay | 2009 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 19, Issue:7
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
| AID1235245 | Inhibition of Pseudoalteromonas haloplanktis gamma-CA after 15 mins by stopped-flow/Co2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID677270 | Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1. |
| AID465236 | Inhibition of human recombinant CA14 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate. |
| AID1237477 | Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for 15 mins at pH 8.3 and 293K by CO2 hydration reaction based colorimetric stopped-flow method | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. |
| AID730753 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID677271 | Inhibition of Helicobacter pylori alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1. |
| AID1235243 | Inhibition of Porphyromonas gingivalis CA after 15 mins by stopped-flow/Co2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID730754 | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID730372 | Inhibition of Flaveria bidentis beta-carbonic anhydrase-1 preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis. |
| AID1461934 | Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assay | | | |
| AID598731 | Inhibition of Salmonella Typhimurium carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 | 2011 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 21, Issue:12
| Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. |
| AID465234 | Inhibition of human recombinant CA9 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate. |
| AID758952 | Inhibition of human recombinant CA2 by CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules. |
| AID1374901 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS assessed as zinc ions ejection from Cys4-Zn finger at 100 uM by FluoZin-3 based fluorescence assay | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID598726 | Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 | 2011 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 21, Issue:12
| Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. |
| AID1058389 | Inhibition of Clostridium perfringens carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens. |
| AID1269931 | Inhibition of Colwellia psychrerythraea gamma carbonic anhydrase expressed in Escherichia coli incubated for 15 mins prior to testing by stopped flow CO2 hydration method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
| AID1161950 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis. |
| AID598732 | Inhibition of Salmonella Typhimurium carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 | 2011 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 21, Issue:12
| Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. |
| AID1374899 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measur | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374895 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 10 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM additi | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374900 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measur | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1235241 | Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assay | 2015 | Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
| Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
| AID730751 | Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
| AID1161932 | Inhibition of recombinant Plasmodium falciparum eta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases. |
| AID714403 | Inhibition of Sulfurihydrogenibium azorense alpha-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23
| Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense. |
| AID1161931 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases. |
| AID1336561 | Inhibition of Pseudoalteromonas haloplanktis recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID730373 | Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis. |
| AID647372 | Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana. |
| AID730368 | Inhibition of Helicobacter pylori beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis. |
| AID1161952 | Inhibition of Porphyromonas gingivalis beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
| Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis. |
| AID552781 | Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives? |
| AID1070022 | Inhibition of Legionella pneumophila carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay | 2014 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 24, Issue:4
| Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
| AID1336557 | Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID552782 | Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives? |
| AID1374902 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS assessed as zinc ions ejection from Cys4-Zn finger at 100 uM by FluoZin-3 based fluorescence assay | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID465235 | Inhibition of human recombinant CA12 by stopped flow CO2 hydration assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate. |
| AID1336562 | Inhibition of Burkholderia pseudomallei recombinant His-tagged carbonic anhydrase gamma expressed in Escherichia coli BL21 (DE3) assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID1374896 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 100 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addit | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374898 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 100 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addit | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID647371 | Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana. |
| AID1336559 | Inhibition of Porphyromonas gingivalis recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method | | | |
| AID229399 | Relative affinity for mu and kappa opioid receptors | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID259396 | Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID235163 | Selectivity ratio expressed as Ki of delta opioid receptor to that of kappa opioid receptor. | 2004 | Journal of medicinal chemistry, Jan-01, Volume: 47, Issue:1
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. |
| AID596551 | Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. |
| AID362196 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membrane | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID1054056 | Reduction of reward potentiation effect of cocaine in ip dosed Sprague-Dawley rat assessed as blockade of cocaine-madiated reduction of intracranial self-stimulation threshold administered for 15 mins prior to cocaine challenge measured 15 mins post dose | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID259402 | Activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID440062 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID670117 | Selectivity index, ratio of inhibition of human mu opioid receptor to inhibition of human kappa opioid receptor | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID148034 | Binding affinity towards Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from guinea pig brain membrane | 2000 | Journal of medicinal chemistry, Jan-13, Volume: 43, Issue:1
| Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. |
| AID229388 | Relative affinity for delta and kappa opioid receptors | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID286312 | Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID1054067 | Displacement of [3H]-U69593 from human kappa opioid receptor transfected in CHO cells after 60 mins | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID1054066 | Displacement of [3H]-naltrindole from human delta opioid receptor transfected in CHO cells after 3 hrs | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID445097 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
| Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. |
| AID296060 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding relative to basal level after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID362201 | Selectivity ratio of Ki for human mu opioid receptor to Ki for human kappa opioid receptor | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID592435 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2011 | Journal of medicinal chemistry, Mar-24, Volume: 54, Issue:6
| Aminothiazolomorphinans with mixed κ and μ opioid activity. |
| AID149977 | Binding ability against kappa opioid receptor by stimulating the [35S]GTP-gamma-S, radioligand in Chinese hamster ovary membranes | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID290265 | Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as DAMGO-stimulated [35S]GTP-gamma-S binding | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID286305 | Ratio of Ki for human opioid kappa receptor to Ki for human opioid gamma receptor | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID286306 | Ratio of Ki for human opioid kappa receptor to Ki for human opioid delta receptor | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID149121 | Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes. | 2004 | Journal of medicinal chemistry, Jan-01, Volume: 47, Issue:1
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. |
| AID286307 | Agonist activity at human opioid kappa receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID670120 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [33S]GTPgammaS binding after 60 mins by scintillation counting relative to control | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID286311 | Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID296061 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID148369 | Inhibitory activity against Opioid receptor delta 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]naltrindole radioligand | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID445098 | Selectivity ratio of Ki for human kappa opioid receptor to Ki for human mu opioid receptor | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
| Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. |
| AID362200 | Selectivity ratio of Ki for human mu opioid receptor to Ki for human delta opioid receptor | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID259395 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID235164 | Selectivity ratio expressed as Ki of delta opioid receptor to that of mu opioid receptor. | 2004 | Journal of medicinal chemistry, Jan-01, Volume: 47, Issue:1
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. |
| AID670113 | Displacement of [3H]-naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID286304 | Displacement of [3H]naltrindole from human opioid delta receptor expressed in CHO cells | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID1274731 | Binding affinity at delta opioid receptor (unknown origin) | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Multitarget opioid ligands in pain relief: New players in an old game. |
| AID290264 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S binding | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID259401 | Functional activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID362199 | Selectivity ratio of Ki for human kappa opioid receptor to Ki for human delta opioid receptor | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID290260 | Selectivity for kappa opioid receptor over delta opioid receptor | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID149270 | Binding affinity towards Opioid receptor kappa 1 by displacing the radioligand [3H]U-69593 from guinea pig brain membrane | 2000 | Journal of medicinal chemistry, Jan-13, Volume: 43, Issue:1
| Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. |
| AID440061 | Selectivity ratio of Ki for human delta opioid receptor to Ki for human kappa opioid receptor | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID286302 | Displacement of [3H]DAMGO from human opioid gamma receptor expressed in CHO cells | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID235329 | Selectivity ratio of kappa opioid receptor to that of delta opioid receptor in guinea pig brain membranes | 2001 | Bioorganic & medicinal chemistry letters, Oct-22, Volume: 11, Issue:20
| Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. |
| AID670110 | Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID670118 | Selectivity index, ratio of inhibition of human delta opioid receptor to inhibition of human kappa opioid receptor | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID465988 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membranes after 3 hrs by scintillation counting | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. |
| AID440064 | Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID149904 | Binding affinity towards Opioid receptor delta 1 in guinea pig brain membranes using [3H]naltrindole as radioligand | 2001 | Bioorganic & medicinal chemistry letters, Oct-22, Volume: 11, Issue:20
| Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. |
| AID296058 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID290256 | Displacement of [3H]DAMGO from human mu opioid receptors expressed in CHO cell membrane | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID223604 | Selectivity kappa/mu | 2000 | Journal of medicinal chemistry, Jan-13, Volume: 43, Issue:1
| Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. |
| AID286314 | Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as inhibition of DAGO-stimulated [35S]GTPgammaS binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID596650 | Selectivity ratio of Ki for human kappa opioid receptor over Ki for human delta opioid receptor | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. |
| AID148327 | Binding ability against Opioid receptor mu 1 by stimulating the [35S]GTP-gamma-S radioligand in Chinese hamster ovary membranes | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID290263 | Antagonist activity against [35S]GTP-gamma-S binding from human kappa opioid receptors expressed in CHO cell membrane | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID445095 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
| Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. |
| AID440068 | Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of U50488-stimulated [35S]GTPgammaS binding | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID596649 | Selectivity ratio of Ki for human kappa opioid receptor over Ki for human mu opioid receptor | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. |
| AID445099 | Selectivity ratio of Ki for human delta opioid receptor to Ki for human mu opioid receptor | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
| Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. |
| AID233831 | Selective inhibitory activity was determined against kappa & mu opioid receptor in chinese Hamster Ovary (CHO) cell membranes | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID149902 | Binding affinity towards Opioid receptor delta 1 by displacing the radioligand [3H]naltrindole from guinea pig brain membrane | 2000 | Journal of medicinal chemistry, Jan-13, Volume: 43, Issue:1
| Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. |
| AID147903 | Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes. | 2004 | Journal of medicinal chemistry, Jan-01, Volume: 47, Issue:1
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. |
| AID286303 | Displacement of [3H]U-69593 from human opioid kappa receptor expressed in CHO cells | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID259398 | Selectivity for human kappa opioid receptor over delta opioid receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID149272 | Binding affinity towards Opioid receptor kappa 1 in guinea pig brain membranes using [3H]U-69593 as radioligand | 2001 | Bioorganic & medicinal chemistry letters, Oct-22, Volume: 11, Issue:20
| Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. |
| AID440060 | Selectivity ratio of Ki for human mu opioid receptor to Ki for human kappa opioid receptor | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID286308 | Agonist activity at human opioid kappa receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID465990 | Selectivity ratio of Ki for human delta opioid receptor to Ki for human kappa opioid receptor | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. |
| AID290258 | Displacement of [3H]naltrindole from human delta opioid receptors expressed in CHO cell membrane | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID148326 | Agonistic activity against Opioid receptor mu 1 in Chinese hamster ovary membranes | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID149976 | Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranes | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID235330 | Selectivity ratio of kappa opioid receptor to that of mu opioid receptor in guinea pig brain membranes | 2001 | Bioorganic & medicinal chemistry letters, Oct-22, Volume: 11, Issue:20
| Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. |
| AID440063 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTPgammaS binding relatiev to DAMGO | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID148158 | Maximal percent inhibitory activity in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes; Not Tested | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID1054059 | Toxicity in Sprague-Dawley rat assessed as suppression of intracranial self-stimulation reward function at 0.25 to 2 mg/kg, ip measured for 1 hr | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID670123 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [33S]GTPgammaS binding after 60 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID296053 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membrane | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID290262 | Agonist activity at huma kappa opioid receptor expressed in CHO cells assessed as U50488-stimulated of [35S]GTP-gamma-S binding | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID296062 | Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID1054064 | Selectivity ratio of Ki for human delta opioid receptor to Ki for human kappa opioid receptor | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID296057 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding relative to basal level after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID259397 | Selectivity for human kappa opioid receptor over mu opioid receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID362197 | Displacement of [3H]Naltindole from human delta opioid receptor expressed in CHO cell membrane | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID296055 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membrane | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID465989 | Selectivity ratio of Ki for human mu opioid receptor to Ki for human kappa opioid receptor | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. |
| AID139099 | Analgesic Potency was tested against mice | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| A Free-Wilson/Fujita-Ban analysis and prediction of the analgesic potency of some 3-hydroxy- and 3-methoxy-N-alkylmorphinan-6-one opioids. |
| AID440059 | Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID148036 | Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligand | 2001 | Bioorganic & medicinal chemistry letters, Oct-22, Volume: 11, Issue:20
| Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. |
| AID259400 | Activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID149994 | Inhibitory activity in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes was determined | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID670122 | Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [33S]GTPgammaS binding after 60 mins by scintillation counting relative to control | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID149978 | Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of Chinese hamster ovary membrane | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID465987 | Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. |
| AID596552 | Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. |
| AID670111 | Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID286313 | Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as maximal inhibition of DAGO-stimulated [35S]GTP-gamma-S binding | 2007 | Journal of medicinal chemistry, May-03, Volume: 50, Issue:9
| Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors. |
| AID465986 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors. |
| AID670124 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [33S]GTPgammaS binding after 60 mins by scintillation counting relative to control | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID440058 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID445096 | Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
| Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors. |
| AID1274735 | Binding affinity at mu opioid receptor (unknown origin) | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Multitarget opioid ligands in pain relief: New players in an old game. |
| AID290261 | Agonist activity at human opioid kappa receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S binding relative to control | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID440066 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID1054065 | Selectivity ratio of Ki for human mu opioid receptor to Ki for human kappa opioid receptor | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID296059 | Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced stimulation of [35S]GTP-gamma-S binding after 60 mins | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID296054 | Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO membrane | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. |
| AID1054068 | Displacement of [3H]-DAMGO from human mu opioid receptor transfected in CHO cells after 60 mins | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID147852 | Percent maximal stimulation in [35S]-GTP-gamma S binding assay mediated by the Opioid receptor kappa 1 in chinese Hamster Ovary (CHO)membranes | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID149778 | Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes. | 2004 | Journal of medicinal chemistry, Jan-01, Volume: 47, Issue:1
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. |
| AID670121 | Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [33S]GTPgammaS binding after 60 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID148149 | Inhibitory activity against Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]U-69593 radioligand | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID147944 | Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membrane | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID223602 | Selectivity kappa/delta | 2000 | Journal of medicinal chemistry, Jan-13, Volume: 43, Issue:1
| Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. |
| AID1274742 | Binding affinity to kappa opioid receptor (unknown origin) | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Multitarget opioid ligands in pain relief: New players in an old game. |
| AID592432 | Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting | 2011 | Journal of medicinal chemistry, Mar-24, Volume: 54, Issue:6
| Aminothiazolomorphinans with mixed κ and μ opioid activity. |
| AID290257 | Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membrane | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| AID148328 | Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membrane | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
| 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. |
| AID440057 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID1054057 | Toxicity in Sprague-Dawley rat assessed as suppression of intracranial self-stimulation reward function at 4 mg/kg, ip measured over 15 to 60 mins | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. |
| AID440067 | Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTPgammaS binding relatiev to U50488 | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. |
| AID233830 | Selective inhibitory activity was determined against kappa & delta opioid receptor in chinese Hamster Ovary (CHO) cell membranes | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID596638 | Displacement of [3H]naltrindole from human delta-opioid receptor expressed in CHO cells after 3 hrs by scintillation counting | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. |
| AID259394 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID670119 | Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [33S]GTPgammaS binding after 60 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8
| Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. |
| AID259399 | Functional activity at human kappa opioid receptor expressed CHO cells by [35S]GTPgammaS binding assay | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors. |
| AID362198 | Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membrane | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors. |
| AID151001 | Inhibitory activity against Opioid receptor mu 1 in chinese Hamster Ovary (CHO) cells membranes was determined using [3H]-DAMGO radioligand | 2003 | Journal of medicinal chemistry, Nov-20, Volume: 46, Issue:24
| Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors. |
| AID290259 | Selectivity for kappa opioid receptor over mu opioid receptor expressed in CHO cells | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6
| High-affinity carbamate analogues of morphinan at opioid receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |