Page last updated: 2024-09-27

Glycogen Storage Disease Type V

Glycogenosis due to muscle phosphorylase deficiency. Characterized by painful cramps following sustained exercise.

Synonyms(1)

Synonym
Glycogen Storage Disease Type V

Research Excerpts

Overview

ExcerptReference
"McArdle disease (Glycogen Storage Disease type V) is caused by an absence of muscle phosphorylase leading to exercise intolerance, myoglobinuria rhabdomyolysis and acute renal failure."( Martinuzzi, A; Quinlivan, R; Schoser, B, 2010)
"McArdle disease (glycogen storage disease type V) is caused by inherited deficiency of a key enzyme in muscle metabolism, the skeletal muscle-specific isoform of glycogen phosphorylase, "myophosphorylase," which is encoded by the PYGM gene."( Arenas, J; Coll-Cantí, J; Godfrey, R; Lucia, A; Martín, MA; Nogales-Gadea, G; Pinós, T; Pintos-Morell, G; Santalla, A, 2016)
"McArdle disease (glycogen storage disease type V) is an inborn error of skeletal muscle metabolism, which affects glycogen phosphorylase (myophosphorylase) activity leading to an inability to break down glycogen."( Brull, A; Krag, TO; Nielsen, TL; Pinós, T; Vissing, J, 2018)

Research

Studies (244)

TimeframeStudies, This Condition (%)All Conditions %
pre-199075 (30.74)23.3326
1990's58 (23.77)12.5806
2000's60 (24.59)18.1394
2010's36 (14.75)28.8240
2020's15 (6.15)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetylcarnitine0low10
adenine0low10
ammonium hydroxide0medium202
carnitine0low60
creatine0medium142
lactic acid0medium405
ethanolamine0low10
glycine0low10
hydrogen0low10
niacin0medium11
pyridoxal phosphate0low20
pyridoxine0low50
pyruvic acid0low30
uric acid0low110
urea0low10
2,4-dinitrophenol0low10
acetaminophen0low10
azathioprine0low10
verapamil0medium22
dantrolene0medium22
valproic acid0low20
furosemide0low10
gentamicin0low10
isoproterenol0low10
nitroglycerin0low10
succinylcholine0low10
prednisone0low20
alanine0low20
serine0low10
sucrose0medium103
adenosine diphosphate0low40
tyrosine0low10
adenosine monophosphate0low20
leucine0low10
asparagine0low10
valine0low10
tryptophan0low10
arginine0low10
pantothenic acid0low10
methysergide0low10
fluorobenzenes0low10
technetium0low40
sodium sulfate0low10
trolamine salicylate0low10
glutamic acid0low10
bezafibrate0low10
vecuronium bromide0low10
atracurium0low10
fomesafen0low20
simvastatin0low20
adenosine0low10
venlafaxine hydrochloride0low10
fluorodeoxyglucose f180low10
glucose-1,6-bisphosphate0low20
vitamin b 60low20
fructose 2,6-diphosphate0low20
ezetimibe0low10
glycogen0medium741
ouabain0low10
buprenorphine0low10
pyrophosphate0low10
D-fructopyranose0low20
coenzyme q100low10
4-hydroxy-2-nonenal0low10
hydromorphone0low10
naloxone0low10
ramipril0medium21
fumarates0low10
phosphorus0low110
phosphocreatine0medium141
technetium tc 99m diphosphonate0low10
ribose0medium31
nad0low30
glucagon0medium61
ubiquinone0low10
technetium tc 99m medronate0low20
hypoxanthine0low60
inosine0low40
allopurinol0low10
phosphorus radioisotopes0low20

Protein Targets (787)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, JmjC domain-containing histone demethylation protein 3A3003
acetylcholinesterase5005
pregnane X receptor3003
RAR-related orphan receptor gamma150015
TDP1 protein110011
GLI family zinc finger 3120012
AR protein220022
aldehyde dehydrogenase 1 family, member A1110011
thyroid stimulating hormone receptor6006
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3120012
glucocorticoid receptor [Homo sapiens]130013
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha100010
estrogen-related nuclear receptor alpha190019
estrogen nuclear receptor alpha260026
67.9K protein1001
peroxisome proliferator-activated receptor delta7007
peroxisome proliferator activated receptor gamma130013
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
aryl hydrocarbon receptor7007
cellular tumor antigen p53 isoform a3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 26006
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
thyroid hormone receptor beta isoform 2120012
histone deacetylase 9 isoform 31001
mitogen-activated protein kinase 12002
nuclear factor erythroid 2-related factor 2 isoform 1160016
nuclear receptor ROR-gamma isoform 14004
geminin9009
survival motor neuron protein isoform d7007
histone acetyltransferase KAT2A isoform 13003
Voltage-dependent calcium channel gamma-2 subunit9009
Cellular tumor antigen p538008
Integrin beta-32013
Integrin alpha-IIb2013
Glutamate receptor 292112
Nuclear receptor ROR-gamma5005
TAR DNA-binding protein 434004
ATPase family AAA domain-containing protein 56006
Ataxin-27007
Microtubule-associated protein tau5005
vitamin D3 receptor isoform VDRA5005
Transient receptor potential cation channel subfamily A member 10011
ATAD5 protein, partial3003
GLS protein6006
Smad33003
progesterone receptor9009
EWS/FLI fusion protein7007
chromobox protein homolog 16006
peripheral myelin protein 227007
cytochrome P450 3A4 isoform 12002
Gamma-aminobutyric acid receptor subunit pi2002
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010010
Solute carrier family 22 member 60202
Carbonic anhydrase 120205
UDP-glucuronosyltransferase 1A90002
Bile salt export pump0808
Bile salt export pump018018
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 104010
Carbonic anhydrase 205112
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20001
Prostaglandin G/H synthase 10101
Carbonic anhydrase 30204
Cytochrome P450 3A40203
Cytochrome P450 2D60202
Cytochrome P450 2C9 0617
Polyunsaturated fatty acid lipoxygenase ALOX150202
Gamma-aminobutyric acid receptor subunit beta-12002
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
UDP-glucuronosyltransferase 1-60002
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0002
Carbonic anhydrase 40306
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60205
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Carbonic anhydrase 5A, mitochondrial0306
Prostaglandin G/H synthase 20102
Carbonic anhydrase 70205
Cytochrome P450 2J20404
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
Carbonic anhydrase 90317
GABA theta subunit2002
Canalicular multispecific organic anion transporter 1010010
Carbonic anhydrase 150103
Carbonic anhydrase 130204
Gamma-aminobutyric acid receptor subunit epsilon2002
Carbonic anhydrase 140205
Carbonic anhydrase 5B, mitochondrial0205
toxin B0001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
cytochrome P450 family 3 subfamily A polypeptide 4100010
pregnane X nuclear receptor140014
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
heat shock protein beta-14004
importin subunit beta-1 isoform 11001
snurportin-11001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
lamin isoform A-delta108008
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0214
Xanthine dehydrogenase/oxidase0404
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 48008
NPYLR7B0033
arylsulfatase A4004
IDH16006
Histone H2A.x8008
glycogen synthase kinase-3 beta isoform 10022
flap endonuclease 15005
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70033
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 32002
Purine nucleoside phosphorylase0102
Epidermal growth factor receptor0101
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0225
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30225
Heat shock 70 kDa protein 1A 0213
Heat shock cognate 71 kDa protein0022
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20203
Endoplasmin0113
Inosine-5'-monophosphate dehydrogenase 1 0203
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0103
Adenosine receptor A10113
Adenosine receptor A30101
Adenosine receptor A2a0135
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0203
Adenosine receptor A10337
Adenosine receptor A2a0113
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0405
Adenosine receptor A10112
Adenosine kinase0001
Adenosine deaminase 0102
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0405
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0405
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0405
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
ATP-dependent molecular chaperone HSP820001
2-dehydropantoate 2-reductase0224
Endoplasmic reticulum chaperone BiP0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor0337
Delta-type opioid receptor0326
Kappa-type opioid receptor0449
Endoplasmin0112
P2Y purinoceptor 20022
P2X purinoceptor 10022
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10112
P2X purinoceptor 40022
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 11001
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
P2Y purinoceptor 110022
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
P2X purinoceptor 20022
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0202
Chain A, Ribonuclease pancreatic0202
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
euchromatic histone-lysine N-methyltransferase 2120012
v-jun sarcoma virus 17 oncogene homolog (avian)100010
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0203
Fructose-1,6-bisphosphatase 10101
Inosine-5'-monophosphate dehydrogenase0102
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
Choline O-acetyltransferase0101
GTP:AMP phosphotransferase AK3, mitochondrial0001
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0112
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase5005
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 05310
Proton-coupled amino acid transporter 10506
Adenosine deaminase0001
Carbonic anhydrase 40001
interleukin 82002
Bloom syndrome protein isoform 13003
transcriptional regulator ERG isoform 31001
ras-related protein Rab-9A2002
Polyphenol oxidase 20203
Hypoxanthine-guanine phosphoribosyltransferase0103
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
Shiga toxin subunit A0101
Histamine H3 receptor0101
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase100010
phosphopantetheinyl transferase8008
NFKB1 protein, partial1001
alpha-galactosidase2002
cytochrome P450 2C19 precursor1001
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)3003
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Neutral amino acid transporter A0202
Neutral amino acid transporter B(0)0202
Carbonic anhydrase-like protein, putative0004
Amino acid transporter0202
Amine oxidase [flavin-containing] A 0011
Small conductance calcium-activated potassium channel protein 30112
Chain A, Ferritin light chain3003
SMAD family member 23003
Fumarate hydratase1001
SMAD family member 33003
thioredoxin glutathione reductase3003
farnesoid X nuclear receptor7007
G6006
polyprotein1001
P531001
thyroid stimulating hormone receptor7007
activating transcription factor 67007
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 12002
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 6006
Inositol hexakisphosphate kinase 16006
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial6006
Luciferase3003
D(1A) dopamine receptor3003
Glutamate receptor ionotropic, NMDA 2D0112
Glutamate receptor ionotropic, NMDA 3B0112
5-hydroxytryptamine receptor 40415
Fatty acid-binding protein, liver0101
Muscarinic acetylcholine receptor M10213
Muscarinic acetylcholine receptor M30112
Muscarinic acetylcholine receptor M40112
Muscarinic acetylcholine receptor M50112
Muscarinic acetylcholine receptor M20112
Fatty acid-binding protein, intestinal0101
Peroxisome proliferator-activated receptor alpha0011
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor gamma0011
Peroxisome proliferator-activated receptor gamma0011
Peroxisome proliferator-activated receptor delta0011
Glutamate receptor ionotropic, NMDA 10112
Peroxisome proliferator-activated receptor alpha0011
Glutamate receptor ionotropic, NMDA 2A0112
Glutamate receptor ionotropic, NMDA 2B0112
Glutamate receptor ionotropic, NMDA 2C0112
Glutamate receptor ionotropic, NMDA 3A0112
Kappa-type opioid receptor0415
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Sodium- and chloride-dependent creatine transporter 10101
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
Glutaminyl-peptide cyclotransferase0101
cytochrome P450 2D67007
potassium voltage-gated channel subfamily H member 2 isoform d3003
neuropeptide S receptor isoform A1001
UDP-glucuronosyltransferase 2B70103
UDP-glucuronosyltransferase 1A30001
Spike glycoprotein5005
Sodium/bile acid cotransporter0202
NPC1-like intracellular cholesterol transporter 10101
NPC1-like intracellular cholesterol transporter 10101
hypoxia-inducible factor 1 alpha subunit3003
thyrotropin-releasing hormone receptor2002
Albumin0112
Glucose-6-phosphate 1-dehydrogenase0101
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Multidrug and toxin extrusion protein 10303
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20213
Chain A, Phosphomannomutase/phosphoglucomutase0011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
glp-1 receptor, partial4004
beta-2 adrenergic receptor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, NMDA 2A 0439
Glutamate receptor ionotropic, NMDA 2B0439
Glutamate receptor ionotropic, NMDA 2C0439
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, NMDA 2D0439
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0202
Glutamate receptor ionotropic, NMDA 3B0439
Alpha-ketoglutarate-dependent dioxygenase FTO0202
Glutamate receptor ionotropic, NMDA 3A0439
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10505
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Solute carrier family 22 member 1 0304
Solute carrier family 22 member 30001
Chain A, Purine-nucleoside Phosphorylase0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain C, Xanthine dehydrogenase/oxidase0011
Purine nucleoside phosphorylase 0012
Chain A, ADENOSINE DEAMINASE0101
Chain A, ADENOSINE DEAMINASE0101
bromodomain adjacent to zinc finger domain 2B4004
Chain A, Hypoxanthine Phosphoribosyltransferase0101
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE0101
Chain A, hypoxanthine phosphoribosyltransferase0011
Chain A, hypoxanthine phosphoribosyltransferase0011
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, Hypoxanthine-guanine phosphoribosyltransferase0101
Beta-1 adrenergic receptor 0012
hexokinase-4 isoform 12002
glucokinase regulatory protein2002
serine/threonine-protein kinase mTOR isoform 11001
Beta-2 adrenergic receptor0225
Beta-1 adrenergic receptor0213
Beta-2 adrenergic receptor0213
Beta-3 adrenergic receptor0112
D(2) dopamine receptor0303
Alpha-1B adrenergic receptor0202
Beta-1 adrenergic receptor0214
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0202
D(1A) dopamine receptor0303
D(4) dopamine receptor0101
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0202
Beta-adrenergic receptor kinase 10011
Alpha-1D adrenergic receptor0011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0011
Alpha-1B adrenergic receptor0011
D(3) dopamine receptor0505
Alpha-1A adrenergic receptor0202
Histamine H2 receptor0011
D(1A) dopamine receptor1001
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0123
Taste receptor type 2 member 160011
Taste receptor type 2 member 140012
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
endonuclease IV1001
dopamine D1 receptor1001
USP1 protein, partial1001
DNA polymerase III, partial1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Alpha-2A adrenergic receptor0404
Alpha-2B adrenergic receptor0202
5-hydroxytryptamine receptor 1A0404
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0404
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60202
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Histidine decarboxylase0011
D(3) dopamine receptor0101
Delta-type opioid receptor0315
Delta-type opioid receptor0224
Kappa-type opioid receptor0102
Mu-type opioid receptor0426
Kappa-type opioid receptor0123
Mu-type opioid receptor0102
Mu-type opioid receptor0213
Sigma non-opioid intracellular receptor 10303
Sigma non-opioid intracellular receptor 10101
UDP-glucuronosyltransferase 1A80001
Sigma non-opioid intracellular receptor 10101
lysosomal alpha-glucosidase preproprotein2002
Amyloid-beta precursor protein0101
Neuronal acetylcholine receptor subunit alpha-41001
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-21001
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)0101
Chain L, Igg2b-kappa 40-50 Fab (light Chain)0101
Chain A, Beta-lactamase2002
Chain A, Na, K-ATPase alpha subunit0011
PPM1D protein1001
STAT3, partial0101
Kruppel-like factor 50101
NPC intracellular cholesterol transporter 1 precursor1001
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Sodium/potassium-transporting ATPase subunit alpha-1 0203
Sodium/potassium-transporting ATPase subunit beta-10203
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Replicase polyprotein 1ab0101
Sodium/potassium-transporting ATPase subunit alpha-30102
Sodium/potassium-transporting ATPase subunit beta-20102
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1A20001
Sodium/potassium-transporting ATPase subunit alpha-20203
Sodium/potassium-transporting ATPase subunit beta-30102
Sodium/potassium-transporting ATPase subunit gamma0102
Potassium voltage-gated channel subfamily H member 20202
Sodium/potassium-transporting ATPase subunit alpha-40102
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Type II pantothenate kinase0001
Type III pantothenate kinase0001
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
Glucocorticoid receptor0213
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Receptor-type tyrosine-protein phosphatase beta0001
Low molecular weight phosphotyrosine protein phosphatase0101
Trans-sialidase0101
Trans-sialidase0101
Chain A, 2-oxoglutarate Oxygenase3003
Pyridoxal kinase0001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Carbonic anhydrase0204
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Solute carrier organic anion transporter family member 2A10101
Angiotensin-converting enzyme 0101
Angiotensin-converting enzyme0101
DNA polymerase kappa isoform 11001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Cholinesterase0101
PINK11001
Parkin1001
photoreceptor-specific nuclear receptor0101
nuclear receptor subfamily 1, group I, member 21001
serine/threonine-protein kinase PLK11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
ATP-dependent translocase ABCB103111
Insulin receptor 0101
Nuclear receptor subfamily 4 group A member 20011
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Solute carrier organic anion transporter family member 1B10303
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Plasma kallikrein0002
Myeloperoxidase0101
Stromelysin-10101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0002
SLC16A10 protein0002
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0002
Tryprostatin B synthase0001
Carbonic anhydrase0002
Carbonic anhydrase0002
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 22 member 60001
Solute carrier family 22 member 80101
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Chain A, Arginase 10101
Cocaine esterase0101
Histone deacetylase 30202
Aldo-keto reductase family 1 member B10101
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
Solute carrier family 22 member 20101
Multidrug and toxin extrusion protein 20101
Sodium-dependent noradrenaline transporter 0101
Sodium-dependent serotonin transporter0303
Sodium-dependent dopamine transporter 0101
glucocerebrosidase1001
huntingtin isoform 21001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
ATP-dependent translocase ABCB10101
Cytochrome P450 2C80101
ATP-dependent translocase ABCB10102
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Histamine H2 receptor0202
Multidrug resistance-associated protein 1 0214
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Chloroquine resistance transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]