Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)

Synonym
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Excerpt	Reference
"Chronic inflammatory demyelinating polyradiculoneuropathy is an autoimmune peripheral neuropathy and would be expected to benefit from corticosteroids."	( Hughes, RA; Mehndiratta, MM, 2001)
"Chronic inflammatory demyelinating polyradiculoneuropathy is a peripheral neuropathy caused by peripheral nerve inflammation probably due to autoimmunity and would be expected to benefit from corticosteroids."	( Hughes, RA; Mehndiratta, MM, 2002)
"Chronic inflammatory demyelinating polyradiculoneuropathy is a disease causing progressive or relapsing and remitting weakness and numbness."	( Hughes, RA; Swan, AV; van Doorn, PA, 2003)
"Chronic inflammatory demyelinating polyradiculoneuropathy is an inflammatory disorder of nerve that usually presents with slowly progressive weakness and sensory loss and areflexia."	( Kissel, JT, 2003)
"Chronic inflammatory demyelinating polyradiculoneuropathy is a disease causing progressive or relapsing and remitting weakness and numbness."	( Hughes, RA; Swan, AV; van Doorn, PA, 2004)
"Chronic inflammatory demyelinating polyradiculoneuropathy is a disease causing progressive or relapsing and remitting weakness and numbness."	( Hughes, RA; Mahdi-Rogers, M; Swan, AV; van Doorn, PA, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	3 (1.10)	12.5806
2000's	110 (40.44)	18.1394
2010's	120 (44.12)	28.8240
2020's	39 (14.34)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
citric acid, anhydrous	low	1	0
lactic acid	low	1	0
glycine	low	1	0
palmitic acid	low	1	0
thiamine	medium	1	1
4-aminopyridine	low	1	0
aspirin	low	1	0
azathioprine	medium	29	1
dapsone	low	1	0
gabapentin	low	1	0
mexiletine	low	1	0
thalidomide	low	1	0
prednisolone	medium	43	9
penicillin g	low	1	0
alanine	low	1	0
lysine	low	1	0
levodopa	low	2	0
berlition	low	1	0
methionine	low	2	0
valine	low	1	0
tryptophan	medium	3	1
arginine	low	1	0
methylprednisolone	medium	42	4
2-methylpentane	low	1	0
n-hexane	low	1	0
calcium gluconate	medium	1	1
azacitidine	low	1	0
chenodeoxycholic acid	low	1	0
digoxigenin	low	1	0
methylprednisolone hemisuccinate	low	1	0
chloric acid	medium	1	1
vidarabine	low	2	0
gadolinium	low	7	0
zalcitabine	low	1	0
triamcinolone	low	1	0
zidovudine	low	1	0
ribavirin	low	1	0
propiconazole	low	1	0
fomesafen	low	6	0
simvastatin	low	1	0
oseltamivir	low	1	0
delphinidin	low	1	0
zoledronic acid	low	2	0
bendamustine hydrochloride	low	2	0
fibrinogen	low	2	0
chlorates	medium	1	1
carbidopa, levodopa drug combination	low	2	0
vitamin b 6	low	1	0
fingolimod hydrochloride	medium	6	1
caprylates	medium	4	3
n(6)-carboxymethyllysine	low	1	0
6-chloropenicillanic acid s-sulfoxide	low	1	0
methotrexate	medium	13	1
biotin	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
bortezomib	low	2	0
n-acetylneuraminic acid	medium	1	1
tacrolimus	low	1	0
mycophenolic acid	medium	10	1
y 27632	low	1	0
tenofovir	low	1	0
fludarabine	low	2	0
ovalbumin	low	1	0
myelin basic protein	low	2	0
dinoprostone	low	1	0
dinoprost	low	1	0
amsonic acid	low	1	0
cholestanol	low	1	0
ganglioside, gd1b	low	1	0
i(3)so3-galactosylceramide	medium	3	1
gadolinium dtpa	low	2	0
g(m1) ganglioside	low	11	0
cs1 peptide	low	1	0
endothelin-1	low	1	0
glycolipids	low	7	0
interleukin-8	low	3	0
siponimod	low	1	0
sofosbuvir	low	1	0
spliceosomal peptide p140	low	1	0
ledipasvir	low	1	0
hyaluronoglucosaminidase	medium	1	1
vitamin b 12	medium	1	1
cyclosporine	medium	12	1
amyloid beta-peptides	medium	1	1
exudates	low	1	0
folic acid	medium	2	1
carbidopa	low	2	0
gq1b ganglioside	low	5	0

Protein Targets (925)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
retinoic acid nuclear receptor alpha variant 1	18	0	0	18
retinoid X nuclear receptor alpha	18	0	0	18
estrogen-related nuclear receptor alpha	26	0	0	26
pregnane X nuclear receptor	15	0	0	15
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	15	0	0	15
Chain A, Cruzipain	2	0	0	2
thioredoxin reductase	12	0	0	12
RAR-related orphan receptor gamma	18	0	0	18
USP1 protein, partial	6	0	0	6
Microtubule-associated protein tau	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	12	0	0	12
thyroid stimulating hormone receptor	11	0	0	11
estrogen receptor 2 (ER beta)	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
glucocorticoid receptor [Homo sapiens]	22	0	0	22
cytochrome P450 2D6	6	0	0	6
glucocerebrosidase	3	0	0	3
IDH1	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	17	0	0	17
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
cytochrome P450 2D6 isoform 1	1	0	0	1
chromobox protein homolog 1	13	0	0	13
transcriptional regulator ERG isoform 3	3	0	0	3
thyroid hormone receptor beta isoform 2	17	0	0	17
mitogen-activated protein kinase 1	3	0	0	3
geminin	22	0	0	22
peripheral myelin protein 22	12	0	0	12
survival motor neuron protein isoform d	6	0	0	6
lethal factor (plasmid)	4	0	0	4
lamin isoform A-delta10	17	0	0	17
Potassium channel subfamily K member 2	0	1	1	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
Cellular tumor antigen p53	18	0	0	18
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
ATP-dependent phosphofructokinase	14	0	0	14
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Carbonic anhydrase 1	0	6	0	9
Carbonic anhydrase 2	0	6	1	10
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	6
Proton-coupled amino acid transporter 1	0	3	0	3
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Luciferase	5	0	0	5
GLS protein	5	0	0	5
hypothetical protein, conserved	2	0	0	2
DNA polymerase kappa isoform 1	6	0	0	6
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	7	0	0	7
NFKB1 protein, partial	4	0	0	4
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	1	0	0	1
flap endonuclease 1	4	0	0	4
DNA polymerase iota isoform a (long)	8	0	0	8
muscarinic acetylcholine receptor M1	7	0	0	7
Cytochrome P450 3A4	0	4	1	6
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	5	0	0	5
AR protein	27	0	0	27
EWS/FLI fusion protein	16	0	0	16
estrogen nuclear receptor alpha	30	0	0	30
peroxisome proliferator-activated receptor delta	12	0	0	12
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Bloom syndrome protein isoform 1	13	0	0	13
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	19
Solute carrier family 22 member 6	0	2	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Bile salt export pump	0	23	0	23
Epidermal growth factor receptor	0	3	0	3
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	3	1	0	4
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	3	1	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	7	0	0	7
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	5	3	1	9
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Canalicular multispecific organic anion transporter 1	0	16	0	16
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, Beta-lactamase	5	0	0	5
glp-1 receptor, partial	6	0	0	6
pregnane X receptor	3	0	0	3
ATAD5 protein, partial	7	0	0	7
Fumarate hydratase	5	0	0	5
PPM1D protein	3	0	0	3
TDP1 protein	21	0	0	21
GLI family zinc finger 3	15	0	0	15
Thrombopoietin	2	0	0	2
Smad3	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
progesterone receptor	11	0	0	11
farnesoid X nuclear receptor	14	0	0	14
polyprotein	5	0	0	5
67.9K protein	7	0	0	7
Parkin	2	0	0	2
peroxisome proliferator activated receptor gamma	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
arylsulfatase A	8	0	0	8
aryl hydrocarbon receptor	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
thyroid stimulating hormone receptor	6	0	0	6
activating transcription factor 6	5	0	0	5
peripheral myelin protein 22 isoform 1	6	0	0	6
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	4	0	0	4
huntingtin isoform 2	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
Interferon beta	8	0	0	8
Adenosine receptor A3	0	2	0	2
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
Spike glycoprotein	7	0	1	8
Multidrug and toxin extrusion protein 1	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
ATPase family AAA domain-containing protein 5	11	0	0	11
Ataxin-2	12	0	0	12
Chain A, Ferritin light chain	7	0	0	7
acetylcholinesterase	6	0	0	6
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
thioredoxin glutathione reductase	5	0	0	5
G	4	0	0	4
P53	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Histone H2A.x	7	0	0	7
heat shock protein beta-1	4	0	0	4
cytochrome P450 3A4 isoform 1	5	0	0	5
M-phase phosphoprotein 8	5	0	0	5
muscleblind-like protein 1 isoform 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	5	2	0	7
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-1	5	2	0	7
Gamma-aminobutyric acid receptor subunit delta	5	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	5	2	1	8
Glutamate receptor 2	9	1	0	10
Gamma-aminobutyric acid receptor subunit alpha-5	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	5	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-1	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	5	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	5	2	0	7
Gamma-aminobutyric acid receptor subunit beta-3	5	2	0	7
Gamma-aminobutyric acid receptor subunit beta-2	5	2	1	8
GABA theta subunit	5	2	0	7
Inositol hexakisphosphate kinase 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	5	2	0	7
Protein-arginine deiminase type-4	0	2	0	2
cytochrome P450 2C9, partial	4	0	0	4
endonuclease IV	1	0	0	1
thyroid hormone receptor beta isoform a	7	0	0	7
DNA polymerase eta isoform 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Cholinesterase	0	2	0	2
Acetylcholinesterase	0	2	0	2
TAR DNA-binding protein 43	7	1	0	8
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
apical membrane antigen 1, AMA1	2	0	0	2
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
vitamin D3 receptor isoform VDRA	6	0	0	6
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	2	0	2
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	2	0	4
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	1	0	3
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	2	0	4
Carbonic anhydrase 6	0	2	0	4
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	2	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	1	0	3
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	2	0	2
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	3	0	5
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	2	0	2
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	3
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Carbonic anhydrase 14	0	2	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	3
Chain A, Beta-lactoglobulin	0	0	1	1
Chain A, Beta-lactoglobulin	0	0	1	1
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	0	1	1
Retinoic acid receptor RXR-alpha	0	0	1	1
Guanine nucleotide-binding protein G	3	0	0	3
Ileal sodium/bile acid cotransporter	0	1	0	1
Bile acid receptor	0	0	1	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile acid receptor	0	0	1	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
cytochrome P450 2C9 precursor	1	0	0	1
Dihydrofolate reductase	0	3	0	3
Histamine H2 receptor	2	0	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	2	1	0	3
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
PAX8	0	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	12
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Solute carrier family 22 member 2	0	0	0	2
Solute carrier family 22 member 1	0	1	0	4
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	3	1	4
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 6	0	0	0	5
Solute carrier family 22 member 7	0	0	0	4
Solute carrier family 22 member 8	0	1	0	6
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	4
Solute carrier family 22 member 7	0	0	0	3
regulator of G-protein signaling 4	5	0	0	5
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Endothelin-1 receptor	0	1	0	1
Sphingosine 1-phosphate receptor 1	0	0	2	2
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
5'-nucleotidase	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine deaminase	0	0	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
acid sphingomyelinase	2	0	0	2
lysosomal alpha-glucosidase preproprotein	1	0	0	1
DNA polymerase beta	3	0	0	3
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
D(1A) dopamine receptor	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	5
Glutamate receptor ionotropic, NMDA 2B	0	2	1	5
Glutamate receptor ionotropic, NMDA 2C	0	2	1	5
Large neutral amino acids transporter small subunit 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2D	0	2	1	5
Glutamate receptor ionotropic, NMDA 3B	0	2	1	5
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Glutamate receptor ionotropic, NMDA 3A	0	2	1	5
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Nonstructural protein 5A	0	1	1	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
dopamine D1 receptor	3	0	0	3
15-lipoxygenase, partial	2	0	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
glucokinase regulatory protein	1	0	0	1
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Polyphenol oxidase 2	0	0	0	1
Plasma kallikrein	0	0	0	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Tyrosinase	0	1	0	1
Carbonic anhydrase	0	0	0	2
Solute carrier family 15 member 1	0	2	0	2
Carbonic anhydrase	0	0	0	2
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
phosphoglycerate kinase	1	0	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
caspase-1 isoform alpha precursor	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
nonstructural protein 1	2	0	0	2
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Potassium channel subfamily K member 3	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	4	1	5
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Cytochrome P450 2J2	0	3	0	3
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Glutamate receptor 1	1	1	0	2
Glutamate receptor 3	1	1	0	2
Glutamate receptor 4	1	1	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Sialidase-4	0	2	0	2
Sialidase-1	0	2	0	2
Sialidase-3	0	2	0	2
Sialidase-2	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
ATP-dependent translocase ABCB1	0	2	0	3
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Chain A, Fatty acid-binding protein, adipocyte	0	1	0	1
Acetylcholinesterase	0	1	0	1
Toll-like receptor 2	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Fatty acid-binding protein, adipocyte	0	2	1	3
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Fatty acid-binding protein 5	0	2	1	3
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase VIM-1	0	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
nuclear receptor ROR-gamma isoform 1	4	0	0	4
Sodium-dependent noradrenaline transporter	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
heat shock protein 90, putative	0	0	0	1
NS5	0	0	2	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Sphingosine 1-phosphate receptor 4	0	0	1	1
Sphingosine 1-phosphate receptor 3	0	0	1	1
Sphingosine 1-phosphate receptor 5	0	0	1	1
Cereblon isoform 4	0	3	0	3
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
RNA-directed RNA polymerase	0	1	2	4
Protein cereblon	0	3	1	5
UDP-glucuronosyltransferase 2B7	0	0	0	2
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Adenylate kinase isoenzyme 1	0	0	0	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Capsid protein	0	0	1	1
Reverse transcriptase/RNaseH	0	3	4	13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	4
Dipeptidyl peptidase 4	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	1	0	1
Chain B, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Rho-associated protein kinase 2	0	2	0	2
Ribosomal protein S6 kinase alpha-5	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
C-C motif chemokine 2	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	0	1
Rho-associated protein kinase 1	0	2	0	2
Serine/threonine-protein kinase N2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
GALC protein	1	0	0	1
Albumin	0	0	2	2
Deoxycytidine kinase	0	1	0	1
C-X-C chemokine receptor type 4	0	0	1	1
pyruvate kinase PKM isoform a	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
Protein kinase C beta type	0	1	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Thymidine kinase	0	1	0	2
Protease	0	1	1	2
Thymidine kinase	0	1	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
72 kDa type IV collagenase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Synonyms(1)

Research Excerpts

Overview

Research

Studies (272)

Protein Targets (925)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Synonyms(1)

Research Excerpts

Overview

Research

Studies (272)

Drugs Studied (107)

Protein Targets (925)