Placental Insufficiency

Failure of the PLACENTA to deliver an adequate supply of nutrients and OXYGEN to the FETUS.

Synonym
Placental Insufficiency

Excerpt	Reference
"Placental insufficiency is a major cause of fetal growth restriction (FGR) and accumulating evidence indicates several aspects of placental morphology are altered in this condition."	( Baker, PN; Crocker, IP; Gowland, PA; Morris, DM; Parker, GJ; Sibley, CP; Wright, C, 2011)
"While utero-placental insufficiency is associated with adverse outcomes for both mother and fetus, many of the maternal-fetal adaptations during pregnancy in models of fetal compromise remain unclear."	( Banek, CT; Bauer, AJ; Chasson, S; Gilbert, JS; Gingery, A, 2012)
"Placental insufficiency is associated with fetal hypoglycemia, hypoxemia, and elevated plasma norepinephrine (NE) that become increasingly pronounced throughout the third trimester and contribute to intrauterine growth restriction (IUGR)."	( Anderson, MJ; Davis, MA; Limesand, SW; Macko, AR; Steyn, LV, 2015)
"Placental insufficiency is often associated with IUGR; however, the molecular mechanisms involved in the pathogenesis of placental insufficiency and IUGR are largely unknown."	( Arck, PC; Barikbin, R; Berger, RG; DeMayo, FJ; Hecher, K; Ho, H; Horst, AK; Jago, C; Karimi, K; Kowal, MK; Lydon, JP; Modest, K; O'Rourke, GE; Parker, VJ; Plösch, T; Remus, CC; Sass, G; Solano, ME, 2015)
"If placental insufficiency is present, the physician must trade off the risk of prolonged fetal exposure to placental insufficiency against the risks of preterm delivery."	( Abaci Turk, E; Adalsteinsson, E; Barnewolt, C; Barth, WH; Bibbo, C; Estroff, J; Gagoski, B; Golland, P; Grant, PE; Luo, J; Malpica, N; Palanisamy, A; Roberts, DJ; Robinson, JN; Tempany-Afdhal, CM; Vangel, M; Zera, C, 2017)

Excerpt	Reference
"Uteroplacental insufficiency has been shown to impair insulin action and glucose homeostasis in adult offspring and may act in part via altered mitochondrial biogenesis and lipid balance in skeletal muscle."	( Cooney, GJ; McConell, GK; Owens, JA; Siebel, AL; Wadley, GD; Wlodek, ME, 2008)

Excerpt	Reference
"Placental insufficiency affects about 10% of pregnancies and can lead to pre-eclampsia, fetal growth restriction, and preterm birth."	( Bussolaro, S; Fantasia, I; Rolnik, DL; Stampalija, T, 2022)

Excerpt	Reference
"Results of treatment of placental insufficiency by transcutaneous electric nerve stimulation (TNS) in 101 patients are demonstrated and compared with a treatment of a special infusion therapy."	( Ketscher, KD; Kindt, J; Retzke, U, 1987)
"Sildenafil is a potential new treatment for placental insufficiency in human pregnancies as it reduces the breakdown of vasodilator nitric oxide."	( Acharya, G; Alanne, L; Bhide, A; Erkinaro, T; Haapsamo, M; Huhta, H; Junno, J; Kokki, M; Ohtonen, P; Rasanen, J, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	225 (46.30)	23.3326
1990's	50 (10.29)	12.5806
2000's	106 (21.81)	18.1394
2010's	87 (17.90)	28.8240
2020's	18 (3.70)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	4	0
ammonium hydroxide	low	2	0
beta-alanine	low	1	0
carnitine	low	3	0
choline	low	1	0
chlorine	low	1	0
salicylic acid	low	1	0
3-hydroxybutyric acid	low	2	0
methylmalonic acid	low	1	0
n(g),n(g')-dimethyl-l-arginine	low	1	0
lactic acid	low	9	0
glycine	low	2	0
dalteparin	medium	1	1
melatonin	low	3	0
nitrates	low	1	0
nitrites	low	2	0
pyridoxine	low	1	0
quinolinic acid	low	2	0
sulfites	low	1	0
taurine	low	2	0
uric acid	low	7	0
urea	low	3	0
vanilmandelic acid	low	1	0
4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridin-3-ol	low	1	0
acebutolol	low	1	0
theophylline	medium	2	1
azathioprine	low	1	0
caffeine	low	1	0
verapamil	low	2	0
chlordiazepoxide	low	1	0
clenbuterol	low	1	0
dipyridamole	medium	3	1
enflurane	low	1	0
berotek	low	5	0
fluphenazine	low	1	0
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	low	1	0
fasudil	low	1	0
hydroxyurea	low	1	0
indomethacin	low	1	0
isoflurane	low	1	0
kynurenic acid	low	2	0
metaproterenol	low	1	0
methadone	low	1	0
metoprolol	low	1	0
apnea	low	1	0
nitroglycerin	medium	4	1
pentoxifylline	low	2	0
pioglitazone	low	1	0
practolol	low	1	0
propranolol	low	1	0
succinylcholine	low	1	0
terbutaline	low	1	0
theobromine	low	2	0
trapidil	low	1	0
corticosterone	low	3	0
prednisolone	low	1	0
estriol	medium	66	2
phentolamine	low	2	0
hydroxyproline	low	1	0
thyroxine	low	3	0
prednisone	low	1	0
estrone	low	5	0
dehydroepiandrosterone	low	14	0
triiodothyronine	low	2	0
alanine	low	2	0
serine	low	3	0
aspartic acid	low	1	0
glutamine	low	2	0
lysine	low	1	0
bromodeoxyuridine	low	2	0
galactose	medium	1	1
phenylephrine	low	5	0
tyrosine	low	1	0
leucine	low	4	0
2-aminoisobutyric acid	low	1	0
androstenedione	low	3	0
methionine	low	2	0
norethindrone	low	1	0
valine	low	2	0
tryptophan	medium	4	1
arginine	low	5	0
pentaerythritol tetranitrate	medium	1	1
4-(dimethylamino)benzaldehyde	low	1	0
isoxazoles	low	1	0
ephedrine	low	1	0
chlormadinone acetate	low	2	0
perfluorotributylamine	low	1	0
aminophylline	low	3	0
betamethasone	low	5	0
xanthinol niacinate	medium	3	1
dihydroergotamine	low	1	0
malondialdehyde	low	4	0
dehydroepiandrosterone sulfate	low	6	0
cytidine diphosphate choline	low	1	0
d-alpha tocopherol	medium	3	1
metanephrine	low	1	0
technetium	low	2	0
magnesium sulfate	medium	1	1
zinc sulfate	medium	1	1
chloramine	low	1	0
estetrol	low	1	0
pregnanolone	low	1	0
du-21220	low	1	0
transferrin	medium	8	1
glutamic acid	low	2	0
glucaric acid	medium	1	1
s-adenosylmethionine	low	2	0
zidovudine	low	1	0
substance p	low	1	0
vecuronium bromide	low	1	0
chlorodiphenyl (54% chlorine)	low	1	0
enkephalin, methionine	low	1	0
captopril	low	3	0
pipecuronium	low	1	0
fomesafen	low	2	0
pravastatin	low	1	0
betamethasone sodium phosphate	low	1	0
nicotine	low	1	0
fibrinogen	low	4	0
homocysteine	low	2	0
5-alpha-dihydroprogesterone	low	1	0
2,2-dimethyl-beta-alanine	low	1	0
vitamin b 6	low	1	0
deoxyglucose	low	1	0
n,n-dimethylarginine	low	1	0
3-(2,2,2-trimethylhydrazine)propionate	low	1	0
proline	low	1	0
indium trichloride	medium	3	1
angiotensin ii	low	6	0
atropine	low	2	0
alanyl-glutamyl-aspartyl-glycine	low	1	0
3-nitrotyrosine	low	1	0
s-adenosylhomocysteine	low	1	0
glycogen	low	5	0
fibrin	low	8	0
elastin	low	4	0
mevalonic acid	low	1	0
oxytocin	low	31	0
nitroarginine	low	1	0
cortodoxone	low	1	0
sodium arsenite	low	1	0
arachidonic acid	low	1	0
resveratrol	low	1	0
retinol	low	1	0
isomethyleugenol	low	1	0
squalene	low	1	0
malonyl coenzyme a	low	1	0
arginine vasopressin	low	2	0
D-fructopyranose	low	1	0
thiopental	low	1	0
cystine	low	1	0
myelin basic protein	low	2	0
bilirubin	low	1	0
dinoprostone	low	2	0
thromboxane a2	low	4	0
cholecalciferol	low	1	0
6-ketoprostaglandin f1 alpha	low	1	0
diosmin	medium	1	1
naloxone	low	1	0
morphine	low	3	0
12-hydroxy-5,8,10,14-eicosatetraenoic acid	low	1	0
15-hydroxy-5,8,11,13-eicosatetraenoic acid	low	1	0
indium	medium	13	1
enalapril	low	2	0
cysteine	low	1	0
selenium	low	2	0
pregnanediol	low	10	0
ferrous fumarate	medium	2	1
formazans	low	1	0
cystathionine	low	1	0
losartan potassium	medium	4	1
acid phosphatase	low	1	0
atrial natriuretic factor	low	2	0
glucagon	low	4	0
beta-endorphin	low	2	0
neuropeptide y	low	1	0
angiotensinogen	low	2	0
ferrous gluconate	medium	1	1
endothelin-1	low	1	0
phosphatidylcholines	low	7	0
sodium pertechnetate tc 99m	low	1	0
fibrinopeptide a	low	1	0
glycolipids	low	8	0
interleukin-8	low	1	0
exenatide	low	1	0
natriuretic peptide, brain	low	2	0
heme	low	1	0
ascorbic acid	medium	3	2
transforming growth factor beta	medium	1	1
glutaminase	low	2	0
caseins	low	1	0
lewis x antigen	low	2	0
angiotensin i	low	1	0
ferric oxide, saccharated	medium	1	1
adrenomedullin	low	1	0
vitamin b 12	medium	3	1
apyrase	low	1	0
cyclic gmp	low	1	0
folic acid	medium	3	1
allopurinol	low	1	0
sildenafil citrate	medium	2	1
leptin	medium	16	1

Protein Targets (1,624)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
thioredoxin reductase	36	0	0	36
ATAD5 protein, partial	18	0	0	18
GLS protein	21	0	0	21
TDP1 protein	41	0	0	41
regulator of G-protein signaling 4	22	0	0	22
67.9K protein	6	0	0	6
Parkin	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	14	0	0	14
IDH1	15	0	0	15
euchromatic histone-lysine N-methyltransferase 2	52	0	0	52
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	13
huntingtin isoform 2	4	0	0	4
ras-related protein Rab-9A	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
survival motor neuron protein isoform d	16	0	0	16
D(1A) dopamine receptor	3	0	0	3
Ataxin-2	14	0	0	14
ATP-dependent phosphofructokinase	19	0	0	19
Proton-coupled amino acid transporter 1	0	10	0	11
Gamma-butyrobetaine dioxygenase	0	2	0	2
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
phosphopantetheinyl transferase	19	0	0	19
pyruvate kinase PKM isoform a	2	0	0	2
geminin	36	0	0	36
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Tubulin--tyrosine ligase	0	2	0	2
Chain A, REPLICASE POLYPROTEIN 1AB	0	1	0	1
AR protein	55	0	0	55
nuclear receptor subfamily 1, group I, member 3	27	0	0	27
retinoic acid nuclear receptor alpha variant 1	36	0	0	36
estrogen nuclear receptor alpha	62	0	0	62
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
histone deacetylase 9 isoform 3	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	37	0	0	37
Cellular tumor antigen p53	29	0	0	29
Cytochrome P450 2A6	0	4	2	6
Cytochrome P450 2A13	0	2	2	4
Gamma-aminobutyric acid receptor subunit pi	16	7	4	27
Gamma-aminobutyric acid receptor subunit beta-1	16	7	4	27
Gamma-aminobutyric acid receptor subunit delta	16	7	4	27
Gamma-aminobutyric acid receptor subunit gamma-2	16	7	5	28
Gamma-aminobutyric acid receptor subunit alpha-5	16	7	4	27
Gamma-aminobutyric acid receptor subunit alpha-3	16	7	4	27
Gamma-aminobutyric acid receptor subunit gamma-1	16	7	4	27
Gamma-aminobutyric acid receptor subunit alpha-2	16	7	4	27
Sodium- and chloride-dependent GABA transporter 1	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-4	16	7	4	27
Gamma-aminobutyric acid receptor subunit gamma-3	16	7	4	27
Gamma-aminobutyric acid receptor subunit alpha-6	16	7	4	27
Sodium- and chloride-dependent GABA transporter 2	0	5	0	5
Sodium- and chloride-dependent GABA transporter 3	0	5	0	5
Sodium- and chloride-dependent betaine transporter	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	16	8	5	29
Gamma-aminobutyric acid receptor subunit beta-3	16	7	4	27
Gamma-aminobutyric acid receptor subunit beta-2	16	7	5	28
GABA theta subunit	16	7	4	27
Gamma-aminobutyric acid receptor subunit epsilon	16	7	4	27
G-protein coupled bile acid receptor 1	0	0	3	3
Solute carrier organic anion transporter family member 2A1	0	0	0	3
vitamin D3 receptor isoform VDRA	14	0	0	14
lamin isoform A-delta10	38	0	0	38
Replicase polyprotein 1ab	0	6	1	7
Replicase polyprotein 1ab	0	6	2	8
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	2	0	2
Solute carrier organic anion transporter family member 1B3	0	10	0	13
Solute carrier organic anion transporter family member 1B1	0	12	0	17
Solute carrier family 22 member 1	0	12	0	15
Beta-2 adrenergic receptor	0	9	12	21
Beta-1 adrenergic receptor	0	8	8	16
Beta-3 adrenergic receptor	0	4	7	11
5-hydroxytryptamine receptor 1A	0	13	3	18
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Carbonic anhydrase 1	0	10	0	17
Carbonic anhydrase 2	0	12	0	20
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	11	2	16
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
glp-1 receptor, partial	12	0	0	12
estrogen-related nuclear receptor alpha	49	0	0	49
NPYLR7B	0	0	2	2
arylsulfatase A	24	0	0	24
thyroid stimulating hormone receptor	19	0	0	19
flap endonuclease 1	10	0	0	10
peripheral myelin protein 22	20	0	0	20
ATP-binding cassette sub-family C member 3	0	30	0	30
Multidrug resistance-associated protein 4	0	31	0	35
Bile salt export pump	0	46	0	46
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	4	0	4
Delta-type opioid receptor	0	7	5	13
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	4	0	4
Beta-2 adrenergic receptor	0	0	5	11
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Beta-2 adrenergic receptor	0	5	7	13
Canalicular multispecific organic anion transporter 1	0	28	0	28
RGS12	2	0	0	2
GLI family zinc finger 3	36	0	0	36
estrogen receptor 2 (ER beta)	18	0	0	18
cytochrome P450 family 3 subfamily A polypeptide 4	25	0	0	25
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	23	0	0	23
thyroid hormone receptor beta isoform 2	37	0	0	37
Alpha-synuclein	4	4	0	8
interleukin 8	10	0	0	10
thyroid stimulating hormone receptor	16	0	0	16
progesterone receptor	27	0	0	27
glucocorticoid receptor [Homo sapiens]	42	0	0	42
Bloom syndrome protein isoform 1	22	0	0	22
transcriptional regulator ERG isoform 3	4	0	0	4
Polyphenol oxidase 2	0	5	0	7
Voltage-dependent calcium channel gamma-2 subunit	16	0	0	16
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Glutamate receptor 2	16	4	1	22
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	7	5	14
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	11	0	0	11
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
pregnane X nuclear receptor	37	0	0	37
USP1 protein, partial	20	0	0	20
Microtubule-associated protein tau	19	0	0	19
Chain A, HADH2 protein	17	0	0	17
Chain B, HADH2 protein	17	0	0	17
acetylcholinesterase	15	0	0	15
RAR-related orphan receptor gamma	31	0	0	31
SMAD family member 2	15	0	0	15
SMAD family member 3	15	0	0	15
Smad3	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
nonstructural protein 1	5	0	0	5
retinoid X nuclear receptor alpha	27	0	0	27
farnesoid X nuclear receptor	19	0	0	19
peroxisome proliferator-activated receptor delta	17	0	0	17
peroxisome proliferator activated receptor gamma	24	0	0	24
Histone H2A.x	15	0	0	15
Caspase-7	5	0	0	5
peripheral myelin protein 22 isoform 1	15	0	0	15
potassium voltage-gated channel subfamily H member 2 isoform d	11	0	0	11
caspase-3	5	0	0	5
importin subunit beta-1 isoform 1	6	0	0	6
mitogen-activated protein kinase 1	9	0	0	9
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	1	3
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	18	0	0	18
nuclear receptor ROR-gamma isoform 1	11	0	0	11
muscleblind-like protein 1 isoform 1	5	0	0	5
neuropeptide S receptor isoform A	9	0	0	9
Sex hormone-binding globulin	0	0	9	9
Beta-glucuronidase	0	2	0	2
Cholinesterase	0	5	0	5
Corticosteroid-binding globulin	0	8	0	8
Aromatase	0	7	0	9
Androgen receptor	0	19	0	19
Gastrin/cholecystokinin type B receptor	0	1	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Nuclear receptor ROR-gamma	14	0	0	14
glucocerebrosidase	9	0	0	9
DNA polymerase kappa isoform 1	16	0	0	16
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	4	0	4
Type-2 angiotensin II receptor	0	2	0	2
D(1A) dopamine receptor	10	0	0	10
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Cruzipain	10	0	0	10
15-lipoxygenase, partial	7	0	0	7
thioredoxin glutathione reductase	9	0	0	9
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
cellular tumor antigen p53 isoform a	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	12	0	0	12
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
cytochrome P450 3A4 isoform 1	16	0	0	16
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
caspase-1 isoform alpha precursor	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Prostaglandin G/H synthase 1	0	2	0	4
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Prostaglandin G/H synthase 2	0	10	2	13
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Histamine H2 receptor	5	0	0	6
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Prostaglandin G/H synthase 2	0	4	0	5
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Lanosterol 14-alpha demethylase	0	1	0	1
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	9	0	0	9
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	6	0	0	6
chromobox protein homolog 1	27	0	0	27
muscarinic acetylcholine receptor M1	14	0	0	14
lethal factor (plasmid)	16	0	0	16
Cytochrome P450 3A4	0	9	2	13
Nitric oxide synthase, endothelial	0	2	0	4
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, inducible	0	4	0	5
Nitric oxide synthase, inducible	0	2	1	5
Cationic amino acid transporter 3	0	2	0	2
Translocator protein	0	2	2	4
Vasopressin V2 receptor	0	3	2	6
Oxytocin receptor	0	3	3	6
Vasopressin V1a receptor	0	1	2	3
Vasopressin V1a receptor	0	4	3	7
Vasopressin V1b receptor	0	2	2	4
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	2	1	4
Translocator protein	0	1	0	2
Oxytocin receptor	0	2	0	2
Vasopressin V2 receptor	0	2	1	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	7	3	13
Spike glycoprotein	16	1	1	18
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Ferritin light chain	9	0	0	9
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	8	2	13
Glutamate receptor ionotropic, NMDA 2B	0	8	2	13
Glutamate receptor ionotropic, NMDA 2C	0	8	2	13
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	8	2	13
Glutamate receptor ionotropic, NMDA 3B	0	8	2	13
Glutamate receptor ionotropic, NMDA 3A	0	8	2	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
EWS/FLI fusion protein	18	0	0	18
cytochrome P450 2D6	12	0	0	12
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Solute carrier family 22 member 6	0	4	0	5
Prostaglandin G/H synthase 2	0	2	0	3
Epidermal growth factor receptor	0	4	1	5
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	3	1	1	5
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	4	1	6
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	3	1	1	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Adenosine receptor A1	1	7	0	11
Adenosine receptor A2a	0	6	1	12
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	3	0	3
Nicotinate phosphoribosyltransferase	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	2	1	3
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	6	0	0	6
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	14	0	14
Muscarinic acetylcholine receptor M2	0	5	2	10
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M1	0	6	2	10
Muscarinic acetylcholine receptor M3	0	6	2	10
Muscarinic acetylcholine receptor M4	0	7	2	11
Muscarinic acetylcholine receptor M5	0	6	2	10
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M2	0	6	2	11
Muscarinic acetylcholine receptor M1	0	5	2	10
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	5	2	9
Alpha-1D adrenergic receptor	0	8	3	13
5-hydroxytryptamine receptor 2C	0	14	1	15
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 7	0	6	0	6
Reverse transcriptase/RNaseH	0	1	2	7
Muscarinic acetylcholine receptor	0	1	1	3
Fumarate hydratase	5	0	0	5
G	14	0	0	14
polyprotein	5	0	0	5
P53	2	0	0	2
aryl hydrocarbon receptor	15	0	0	15
activating transcription factor 6	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
hemoglobin subunit beta	1	0	0	1
heat shock protein beta-1	8	0	0	8
M-phase phosphoprotein 8	8	0	0	8
Bile salt export pump	0	7	0	7
Interferon beta	18	0	0	18
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Inositol hexakisphosphate kinase 1	14	0	0	14
ATPase family AAA domain-containing protein 5	9	0	0	9
Protein-arginine deiminase type-4	0	1	0	1
cytochrome P450 2C9, partial	14	0	0	14
beta-2 adrenergic receptor	4	0	0	4
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
pregnane X receptor	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
thyroid hormone receptor beta isoform a	13	0	0	13
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	16	2	23
Glycine receptor subunit alpha-1	0	16	0	16
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
ORF73	0	0	1	1
Caspase-7	3	0	0	3
Inositol monophosphatase 1	10	0	0	10
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	3	0	4
Thymidine phosphorylase	0	0	1	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	4	5
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	7	1	8
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	7	0	7
Amine oxidase [flavin-containing] B	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A2b	0	4	0	6
Adenosine receptor A1	0	6	2	12
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	3	5
Endochitinase B1	0	4	1	5
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Guanine deaminase	0	2	0	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Thrombopoietin	4	0	0	4
Metallo-beta-lactamase type 2	0	1	1	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Prothrombin	0	1	2	3
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	4	1	5
Angiotensin-converting enzyme	0	7	0	8
Leukotriene A-4 hydrolase	0	1	0	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	7	3	10
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	3	1	4
Beta-lactamase class B VIM-2	0	1	1	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	5	1	6
Cholecystokinin receptor type A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	1	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	1	6
Histamine H1 receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	1	6
Carbonic anhydrase 4	0	7	0	10
Carbonic anhydrase	0	4	0	6
Carbonic anhydrase 15	0	6	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
Cytochrome P450 2C19	0	5	0	5
Luciferase	10	0	0	10
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	4	0	6
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	1	6	3	11
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	1	6	3	11
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Solute carrier family 22 member 1	0	4	0	5
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Solute carrier family 22 member 2	0	4	0	5
5-hydroxytryptamine receptor 1B	0	10	0	10
GALC protein	5	0	0	5
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Mineralocorticoid receptor	0	2	2	4
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	6
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
endonuclease IV	4	0	0	4
Cytochrome P450 1A2	0	6	0	7
Cytochrome P450 2A5	0	2	0	2
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	1	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	5	0	5
Rap guanine nucleotide exchange factor 3	7	0	0	7
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	1	0	5
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Steryl-sulfatase	0	2	0	3
Multidrug resistance-associated protein 1	0	3	1	6
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Solute carrier organic anion transporter family member 1A3	0	2	0	6
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	1	0	4
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
dopamine D1 receptor	3	0	0	3
caspase 7, apoptosis-related cysteine protease	6	0	0	6
caspase-3	6	0	0	6
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	14	1	25
Alpha-2A adrenergic receptor	0	12	5	20
D(2) dopamine receptor	0	7	1	8
Alpha-1B adrenergic receptor	0	8	4	12
Alpha-2C adrenergic receptor	0	10	4	17
Alpha-2B adrenergic receptor	0	3	4	7
ATP-dependent translocase ABCB1	0	3	0	4
D(1A) dopamine receptor	0	5	1	6
Alpha-2C adrenergic receptor	0	3	4	7
Alpha-2A adrenergic receptor	0	3	4	7
Alpha-1D adrenergic receptor	0	4	4	9
5-hydroxytryptamine receptor 2A	0	10	1	11
Alpha-1A adrenergic receptor	0	4	5	11
Alpha-1B adrenergic receptor	0	3	4	9
D(3) dopamine receptor	0	8	0	8
5-hydroxytryptamine receptor 2B	0	14	1	15
Alpha-1A adrenergic receptor	0	9	4	13
5-hydroxytryptamine receptor 6	0	6	1	7
Multidrug and toxin extrusion protein 2	0	3	0	3
Multidrug and toxin extrusion protein 1	0	5	0	5
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier family 22 member 6	0	3	0	6
Solute carrier family 22 member 7	0	1	0	5
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	4	0	6
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 7	0	1	0	3
PPM1D protein	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
DNA polymerase eta isoform 1	3	0	0	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	0	2
Lysine-specific histone demethylase 1A	0	2	0	2
Aurora kinase B	0	1	1	2
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
acid sphingomyelinase	2	0	0	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
LANA	0	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
serine-protein kinase ATM isoform a	1	0	0	1
cytochrome P450 2D6 isoform 1	6	0	0	6
lysosomal alpha-glucosidase preproprotein	5	0	0	5
cytochrome P450 2C9 precursor	2	0	0	2
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
tumor susceptibility gene 101 protein	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Exopolyphosphatase PRUNE1	0	1	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
Equilibrative nucleoside transporter 1	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Beta-2 adrenergic receptor	0	3	0	5
Beta-3 adrenergic receptor	0	2	1	3
Solute carrier family 15 member 1	0	1	0	1
Endothelin-1 receptor	0	2	1	3
Estrogen receptor	0	9	1	11
UDP-glucuronosyltransferase 2B7	0	0	0	2
Sodium-dependent serotonin transporter	0	14	0	14
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	3	3
UDP-glucuronosyltransferase 1A10	0	0	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	9	5	17
Cytochrome P450 1B1	0	4	0	4
Estrogen receptor beta	0	3	1	5
Ghrelin O-acyltransferase	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	1	0	1
Chain B, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	0	0	0	1
serine/threonine-protein kinase 33 isoform a	0	0	1	2
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	2
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	2	1	3
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	1	1	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	3
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	1	2
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	2	1	3
Cyclin-dependent kinase 1	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Cytochrome P450 2D6	0	5	0	6
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	1	1	3
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
C-C motif chemokine 2	0	1	0	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	4	2	6
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	2	1	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	2	1	3
cAMP-dependent protein kinase catalytic subunit beta	0	2	1	3
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	1	1	2
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	1	1	2
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	2	0	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Myotonin-protein kinase	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	2	1	3
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	2	1	3
Mitogen-activated protein kinase 11	0	1	1	2
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	1	1	2
Serine/threonine-protein kinase N2	0	1	1	2
Mitogen-activated protein kinase 14	0	2	1	3
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
D(4) dopamine receptor	0	4	0	4
Delta-type opioid receptor	0	7	1	10
Kappa-type opioid receptor	0	4	3	8
Mu-type opioid receptor	0	11	4	17
Delta-type opioid receptor	0	10	3	15
Kappa-type opioid receptor	0	7	1	8
Kappa-type opioid receptor	0	10	4	16
Mu-type opioid receptor	0	4	1	8
Sigma non-opioid intracellular receptor 1	0	4	1	5
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Transmembrane protease serine 2	0	1	1	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Procathepsin L	0	2	1	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Replicase polyprotein 1a	0	2	1	3
Replicase polyprotein 1ab	0	1	1	2
Substance-K receptor	0	6	0	6
D(1B) dopamine receptor	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	2	6
Histamine H2 receptor	0	4	0	4
Trypanothione reductase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Histamine H3 receptor	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Gamma-aminobutyric acid	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	3	4
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	2	2
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	2	2
Gamma-aminobutyric acid receptor subunit delta	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	0	0	2	2
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	0	2	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	2	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	2	2
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	4	1	6
Glutamate receptor 3	0	4	1	6
Glutamate receptor 4	0	4	1	6
Glutamate receptor ionotropic, kainate 1	0	3	1	5
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	3	1	5
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	3	0	4
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	3	0	4
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	4	0	4
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	4	0	4
Amino acid transporter	0	4	0	4
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	6	0	6
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
calpain II, partial	0	1	0	1
PAX8	0	0	0	1
SUMO-1	0	1	0	1
Mcl-1	0	1	0	1
Valosin-containing protein	0	1	0	1
TSHR protein	1	0	0	1
Estrogen receptor 1	0	1	0	1
PINK1	2	0	0	2
envelope glycoprotein	0	1	0	1
heat shock protein 90	0	0	1	1
heat shock 70kDa protein 1A	0	1	0	1
galactokinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
neuropeptide Y receptor type 1	0	0	1	1
neuropeptide Y receptor type 2	0	0	1	1
small ubiquitin-related modifier 2 isoform b precursor	0	1	0	1
estrogen receptor beta isoform 1	0	2	0	2
enteropeptidase precursor	1	0	0	1
fatty acid synthase	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vpr	1	0	0	1
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
streptokinase A precursor	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
POsterior Segregation	0	0	2	2
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Estrogen receptor	0	0	2	2
Urokinase-type plasminogen activator	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Macrophage migration inhibitory factor	0	2	0	2
Thromboxane-A synthase	0	2	0	2
Estrogen receptor beta	0	0	2	2
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
phosphoglycerate kinase	1	0	0	1
heat shock protein 90, putative	0	0	0	1
M1-family alanyl aminopeptidase	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
BZLF2	0	1	0	1
large T antigen	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	3	0	4
Stromelysin-1	0	1	2	3
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	3	0	6
Urease subunit beta	0	2	0	2
Carbonic anhydrase 9	0	3	0	7
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	5
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Albumin	0	2	4	6
Interleukin-8	0	1	0	1
Androgen receptor	0	3	1	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	7	10
Aldo-keto reductase family 1 member C3	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	6
Mitogen-activated protein kinase 13	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Mitogen-activated protein kinase 12	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
Vesicular glutamate transporter 3	0	1	0	1
G-protein coupled receptor 35	0	2	1	3
Histamine H3 receptor	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
ClpP	3	0	0	3
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	1	3
Carboxylic ester hydrolase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Mas-related G-protein coupled receptor member X2	0	0	3	3
Aldehyde oxidase 1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	2	0	2
Serine racemase	0	1	0	1
Beta-1 adrenergic receptor	0	1	3	5
Cytochrome P450 2C9	0	6	0	6
Beta-1 adrenergic receptor	0	4	3	9
Beta-1 adrenergic receptor	0	2	0	2
Cytochrome P450 2J2	0	5	0	5
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	3	0	3
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	2	2
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	1	0	1
Kappa-type opioid receptor	0	3	1	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
D(3) dopamine receptor	0	3	0	3
UDP-glucuronosyltransferase 1A8	0	0	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
Sodium/iodide cotransporter	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Nitric oxide synthase, inducible	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Progesterone receptor	0	4	2	7
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Oxytocin receptor	0	0	1	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	2	0	2
Nischarin	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Synaptic vesicle glycoprotein 2A	0	1	0	1
Renin	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier family 22 member 8	0	1	0	2
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Glutamate 5-kinase	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Cytochrome P450 2C8	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Advanced glycosylation end product-specific receptor	0	0	1	1
Beta-lactamase	0	1	0	1
Advanced glycosylation end product-specific receptor	0	0	1	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
pyruvate kinase	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	2
Carbonic anhydrase 12	0	2	0	5
Myc proto-oncogene protein	0	1	0	2
Transthyretin	0	1	1	4
Amyloid-beta precursor protein	0	2	1	3
Cathepsin D	0	1	0	1
Carbonic anhydrase 3	0	2	0	5
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Tyrosinase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	2
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Endothelin receptor type B	1	0	0	1
Carbonic anhydrase 6	0	2	0	5
Sucrase-isomaltase, intestinal	0	1	0	1
Endothelin-1 receptor	1	0	0	1
Dipeptidyl peptidase 4	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Carbonic anhydrase 7	0	2	0	5
Cannabinoid receptor 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Cholinesterase	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Squalene synthase	0	1	0	1
Transcription factor p65	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Tubulin beta-2B chain	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
Carbonic anhydrase 13	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Carbonic anhydrase 14	0	2	0	5
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Adenine-n6-dna-methyltransferase Taqi	0	0	1	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Ermc' Methyltransferase	0	1	0	1
Chain A, Ermc' Rrna Methyltransferase	0	1	0	1
Chain A, Uroporphyrin-III C-methyltransferase	0	1	0	1
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
tRNA (cytosine(38)-C(5))-methyltransferase	0	1	1	2
Protein arginine N-methyltransferase 5	0	1	1	2
Histone-lysine N-methyltransferase SUV39H1	0	2	0	2
Adenosylhomocysteinase	0	0	0	1
Protein arginine N-methyltransferase 3	0	1	0	1
Indolethylamine N-methyltransferase	0	1	0	1
Histone-lysine N-methyltransferase NSD2	0	1	0	1
Adenosylhomocysteinase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
Phenylethanolamine N-methyltransferase	0	1	1	3
rRNA adenine N-6-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Histone-lysine N-methyltransferase SETDB1	0	1	0	1
Retinoblastoma-binding protein 5	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N6-adenosine-methyltransferase catalytic subunit	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Histone-lysine N-methyltransferase KMT5C	0	1	0	1
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	2	1	3
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Histone-lysine N-methyltransferase EZH1	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
Protein arginine N-methyltransferase 1	0	3	0	3
Methylosome protein 50	0	1	1	2
Protein dpy-30 homolog	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Histone-lysine N-methyltransferase SUV39H2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N-lysine methyltransferase SMYD2	0	1	0	1
Protein arginine N-methyltransferase 7	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Set1/Ash2 histone methyltransferase complex subunit ASH2	0	1	0	1
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Non-structural protein 1	0	1	0	1
Met repressor	0	0	2	2
Histone H3K27 methylase	0	0	0	1
S-adenosylmethionine decarboxylase proenzyme	0	1	0	2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	3
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Squalene monooxygenase	0	0	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
D(2) dopamine receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	2	0	2
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
apical membrane antigen 1, AMA1	2	0	0	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Plasma kallikrein	0	0	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	2
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	0	0	2
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Taste receptor type 2 member 14	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidine kinase	0	1	0	2
Protease	0	1	1	2
Thymidine kinase	0	1	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (486)

Protein Targets (1,624)

Placental Insufficiency

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (486)

Drugs Studied (238)

Protein Targets (1,624)