histamine has been researched along with Cystitis, Interstitial in 6 studies
Cystitis, Interstitial: A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by overexpression of monocyte chemoattractant protein-1 (MCP-1) in bladder tissues and induction of mast cell (MC) degranulation." | 5.38 | MCP-1-induced histamine release from mast cells is associated with development of interstitial cystitis/bladder pain syndrome in rat models. ( Bo, J; Huang, Y; Leng, J; Liu, D; Lv, J; Yang, G; Zhang, Y; Zhu, S, 2012) |
| "The topic of interstitial cystitis (IC), also known as painful bladder syndrome (PBS), and folate/one carbon metabolism has previously been unaddressed in research." | 2.61 | The potential role of folate metabolism in interstitial cystitis. ( Keagy, CD, 2019) |
| "Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by overexpression of monocyte chemoattractant protein-1 (MCP-1) in bladder tissues and induction of mast cell (MC) degranulation." | 1.38 | MCP-1-induced histamine release from mast cells is associated with development of interstitial cystitis/bladder pain syndrome in rat models. ( Bo, J; Huang, Y; Leng, J; Liu, D; Lv, J; Yang, G; Zhang, Y; Zhu, S, 2012) |
| "A total of 40 women with interstitial cystitis and 29 healthy controls collected 24-hour urine samples." | 1.33 | Interleukin-6, histamine, and methylhistamine as diagnostic markers for interstitial cystitis. ( Kreder, KJ; Lamale, LM; Lutgendorf, SK; Zimmerman, MB, 2006) |
| "Many patients with interstitial cystitis (IC) also have irritable bowel syndrome (IBS), both of which occur overwhelmingly in women, are characterized by pain, and worsen under stress." | 1.29 | Mast cell and substance P-positive nerve involvement in a patient with both irritable bowel syndrome and interstitial cystitis. ( Boucher, W; Pang, X; Sant, GR; Theoharides, TC; Triadafilopoulos, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Grundy, L | 1 |
| Caldwell, A | 1 |
| Garcia Caraballo, S | 1 |
| Erickson, A | 1 |
| Schober, G | 1 |
| Castro, J | 1 |
| Harrington, AM | 1 |
| Brierley, SM | 1 |
| Keagy, CD | 1 |
| Lv, J | 1 |
| Huang, Y | 1 |
| Zhu, S | 1 |
| Yang, G | 1 |
| Zhang, Y | 1 |
| Leng, J | 1 |
| Bo, J | 1 |
| Liu, D | 1 |
| Lamale, LM | 1 |
| Lutgendorf, SK | 1 |
| Zimmerman, MB | 1 |
| Kreder, KJ | 1 |
| Pang, X | 1 |
| Boucher, W | 1 |
| Triadafilopoulos, G | 1 |
| Sant, GR | 1 |
| Theoharides, TC | 1 |
| Bouchelouche, K | 1 |
| Horn, T | 1 |
| Nordling, J | 1 |
| Larsen, S | 1 |
| Hald, T | 1 |
| Bouchelouche, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acupuncture for Female Interstitial Cystitis/Painful Bladder Syndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial[NCT02232282] | 22 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Mediators of Neurogenic Inflammation in the Urinary Tract as Key Factors in the Painful Bladder Syndrome / Interstitial Cystitis and Bladder Dysfunction[NCT00775281] | 45 participants (Anticipated) | Observational | 2006-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in worst pain as measured by the Brief Pain Inventory-Short Form. Scores range from 0 to 10 and higher scores indicate more pain. Change is calculated as the 6 weeks score minus the baseline score. (NCT02232282)
Timeframe: 0 weeks, 6 weeks
| Intervention | score on a scale (Least Squares Mean) |
|---|---|
| Minimal Acupuncture | -2.08 |
| Standard Acupuncture Treatment | -2.91 |
The total number of adverse events experienced by women receiving acupuncture (NCT02232282)
Timeframe: 0 weeks, 12 weeks
| Intervention | total number of adverse events (Number) |
|---|---|
| Minimal Acupuncture | 0 |
| Standard Acupuncture Treatment | 0 |
The total number of acupuncture sessions stopped due to poor tolerability of acupuncture (NCT02232282)
Timeframe: 0 weeks, 6 weeks
| Intervention | total number of sessions (Number) |
|---|---|
| Minimal Acupuncture | 0 |
| Standard Acupuncture Treatment | 0 |
1 review available for histamine and Cystitis, Interstitial
| Article | Year |
|---|---|
The potential role of folate metabolism in interstitial cystitis.
Topics: Cystitis, Interstitial; Endothelium; Female; Folic Acid; Histamine; Humans; Hypersensitivity; Mast C | 2019 |
5 other studies available for histamine and Cystitis, Interstitial
| Article | Year |
|---|---|
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H
Topics: Administration, Intravesical; Animals; Calcium Signaling; Cells, Cultured; Cystitis, Interstitial; F | 2020 |
MCP-1-induced histamine release from mast cells is associated with development of interstitial cystitis/bladder pain syndrome in rat models.
Topics: Animals; Cell Line; Chemokine CCL2; Cystitis, Interstitial; Female; Flow Cytometry; Histamine; Hista | 2012 |
Interleukin-6, histamine, and methylhistamine as diagnostic markers for interstitial cystitis.
Topics: Adult; Aged; Biomarkers; Cystitis, Interstitial; Female; Histamine; Humans; Interleukin-6; Methylhis | 2006 |
Mast cell and substance P-positive nerve involvement in a patient with both irritable bowel syndrome and interstitial cystitis.
Topics: Chymases; Colon; Colonic Diseases, Functional; Cystitis, Interstitial; Female; Histamine; Humans; Ma | 1996 |
Calcium signaling in cultured human detrusor smooth muscle cells from patients with interstitial cystitis.
Topics: Calcium; Cell Division; Cystitis, Interstitial; Female; Histamine; Humans; Leukotriene D4; Muscle, S | 2001 |