cimetidine has been researched along with Cystitis, Interstitial in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Cystitis, Interstitial: A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 7.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 3.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| "Interstitial cystitis (IC) and bladder pain syndrome (BPS) are chronic conditions that can be debilitating for patients." | 2.58 | An evaluation of the pharmacotherapy for interstitial cystitis. ( Giusto, LL; Shoskes, DA; Zahner, PM, 2018) |
| "The typical patient with interstitial cystitis (IC) is symptomatic for many years and consults multiple physicians before IC is diagnosed." | 2.44 | [Interstitial cystitis in 2008]. ( Mouracade, P; Saussine, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giusto, LL | 1 |
| Zahner, PM | 1 |
| Shoskes, DA | 1 |
| Dancel, R | 1 |
| Mounsey, A | 1 |
| Handler, L | 1 |
| Mouracade, P | 1 |
| Saussine, C | 1 |
| Sea, J | 1 |
| Teichman, JM | 1 |
| Tincello, DG | 1 |
| Walker, AC | 1 |
| Lewi, H | 1 |
| Dasgupta, P | 1 |
| Sharma, SD | 1 |
| Womack, C | 1 |
| Blackford, HN | 1 |
| Dennis, P | 1 |
3 reviews available for cimetidine and Cystitis, Interstitial
| Article | Year |
|---|---|
An evaluation of the pharmacotherapy for interstitial cystitis.
Topics: Amitriptyline; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Cimetidine; Cystitis, Inter | 2018 |
[Interstitial cystitis in 2008].
Topics: Adolescent; Adult; Algorithms; Anti-Ulcer Agents; Biopsy; Cimetidine; Cyclosporins; Cystectomy; Cyst | 2008 |
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.
Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy | 2009 |
4 other studies available for cimetidine and Cystitis, Interstitial
| Article | Year |
|---|---|
Medications for treatment of interstitial cystitis.
Topics: Adult; Amitriptyline; Cimetidine; Cystitis, Interstitial; Evidence-Based Medicine; Female; Humans; H | 2015 |
Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group.
Topics: Anticonvulsants; Cimetidine; Cystitis, Interstitial; Depression; Dimethyl Sulfoxide; Female; Histami | 2005 |
Medical therapy in interstitial cystitis: the essex experience.
Topics: Administration, Oral; Cimetidine; Cystitis, Interstitial; Drug Therapy, Combination; Histamine H2 An | 2001 |
Cimetidine in painful bladder syndrome: a histopathological study.
Topics: Cimetidine; Cystitis, Interstitial; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Mal | 2001 |