Progeria

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

Synonym
Progeria

Excerpt	Reference
"Hutchinson-Gilford progeria is a unique, rare disease with markedly accelerated aging."	( Davidson, JM; Giro, MG; Sephel, GC; Sturrock, A, 1988)
"Progeria is an autosomal recessive disorder showing precocious senility."	( Danes, BS, 1971)
"Progerias are rare genetic diseases characterized by premature aging."	( Coffinier, C; Fong, LG; Frost, D; Meta, M; Qiao, X; Yang, SH; Young, SG, 2006)
"Progeria is characterized by clinical features that mimic premature ageing."	( Ghosh, S; Raghunath, M; Sinha, JK, 2014)
"Progeria is a rare genetic disorder characterized by premature aging that eventually leads to death and is noticed globally."	( Baek, A; Cho, Y; Choi, Y; Kim, D; Kumar, R; Lee, G; Lee, KW; Park, C; Park, SJ; Park, Y; Rampogu, S; Son, M; Zeb, A, 2017)
"Hutchinson-Gilford progeria is a premature aging syndrome caused by a truncated form of lamin A called progerin."	( Chojnowski, A; Dreesen, O; Foo, MXR; Hor, LP; Liebl, D; Ong, PF; Stewart, CL, 2020)
"In particular, progeria is caused by a point mutation in the gene that codifies for the lamin A gene."	( Macicior, J; Marcos-Ramiro, B; Ortega-Gutiérrez, S, 2021)

Excerpt	Reference
"Rapamycin treatment of progeria cells lowers progerin, as well as wild-type prelamin A levels, and rescues the chromatin phenotype of cultured fibroblasts, including histone methylation status and BAF and LAP2alpha distribution patterns."	( Capanni, C; Cenni, V; Columbaro, M; D'Apice, MR; Fini, M; Lattanzi, G; Maraldi, NM; Marmiroli, S; Novelli, G; Ortolani, M; Prencipe, S; Scarano, E; Squarzoni, S, 2011)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	98 (29.17)	23.3326
1990's	22 (6.55)	12.5806
2000's	39 (11.61)	18.1394
2010's	138 (41.07)	28.8240
2020's	39 (11.61)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	2	0
quinacrine	low	1	0
choline	low	1	0
chlorine	low	1	0
salicylic acid	low	1	0
hydrogen sulfide	low	2	0
cytosine	low	1	0
lactic acid	low	1	0
glycine	low	1	0
glycerol	low	2	0
pyruvaldehyde	low	1	0
melatonin	low	1	0
nitrites	low	1	0
phosphorylcholine	low	1	0
diphosphoric acid	low	3	0
pyruvic acid	low	1	0
spermidine	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
aminopropionitrile	low	1	0
acetaminophen	low	1	0
berberine	low	1	0
chloroquine	low	1	0
dipyridamole	low	1	0
fluorouracil	low	1	0
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	low	1	0
fasudil	low	1	0
iofetamine	low	1	0
2-propanol	low	1	0
khellin	low	4	0
losartan	low	1	0
mechlorethamine	low	1	0
metformin	low	3	0
nocodazole	low	1	0
metyrapone	low	2	0
activins	low	1	0
piracetam	medium	1	1
potassium chloride	low	1	0
propofol	low	1	0
propranolol	low	1	0
sulforaphane	low	1	0
tolbutamide	low	2	0
mitomycin	low	2	0
prednisolone	low	1	0
thymidine	low	12	0
thyroxine	low	1	0
penicillin g	low	1	0
triiodothyronine	low	1	0
alanine	low	1	0
serine	low	2	0
chloramphenicol	low	1	0
aspartic acid	low	1	0
lysine	low	5	0
cyanides	low	1	0
methyltestosterone	low	3	0
adenosine diphosphate	low	1	0
uridine	low	1	0
bromodeoxyuridine	low	1	0
galactose	low	1	0
carbostyril	low	2	0
tyrosine	low	1	0
methylene blue	low	2	0
leucine	low	2	0
ethyl methanesulfonate	low	1	0
methionine	low	7	0
phenylalanine	low	2	0
asparagine	low	2	0
histidine	low	2	0
threonine	low	2	0
arginine	low	4	0
2-aminopyrimidine	low	1	0
quinazolines	low	1	0
thiazoles	low	2	0
malondialdehyde	low	2	0
acetylcysteine	low	2	0
d-alpha tocopherol	low	3	0
cadmium	low	1	0
isopentenyladenosine	low	1	0
trolamine salicylate	low	1	0
levamisole	low	1	0
tetradecanoylphorbol acetate	low	1	0
fluorides	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
transferrin	low	1	0
glutamic acid	low	1	0
paclitaxel	low	1	0
etoposide	low	2	0
propiconazole	low	1	0
fomesafen	low	1	0
lovastatin	low	3	0
adenosine	low	1	0
glutathione disulfide	low	1	0
homocysteine	low	1	0
lopinavir	low	1	0
n-methyladenosine	low	1	0
deoxyglucose	low	2	0
peroxynitrous acid	low	1	0
imatinib mesylate	low	2	0
xylose	low	1	0
proline	low	1	0
atazanavir sulfate	low	1	0
tipifarnib	low	3	0
tevenel	low	1	0
paromomycin	low	1	0
3-(2-carboxyindol-3-yl)propionic acid	low	1	0
angiotensin ii	low	2	0
sb 203580	low	1	0
demecolcine	low	1	0
taurochenodeoxycholic acid	low	1	0
bortezomib	low	1	0
leupeptins	low	2	0
fibrin	low	1	0
elastin	low	11	0
mevalonic acid	low	1	0
inositol 3-phosphate	low	1	0
acetyl coenzyme a	low	1	0
trichostatin a	low	1	0
tretinoin	low	2	0
resveratrol	low	5	0
oleic acid	low	1	0
tacrolimus	low	1	0
y 27632	low	2	0
bms 214662	low	1	0
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	2	0
isomethyleugenol	low	11	0
stilbenes	low	5	0
pyrophosphate	low	4	0
curcumin	low	1	0
dermatan sulfate	low	1	0
dasatinib	low	1	0
17-ketosteroids	low	3	0
osteoprotegerin	low	1	0
quercetin	low	1	0
calcitriol	low	2	0
alprostadil	low	1	0
vitamin d 2	low	1	0
cholecalciferol	low	1	0
isotretinoin	low	1	0
phenylephrine hydrochloride	low	3	0
sirolimus	low	13	0
casein kinase ii	low	1	0
arsenic	low	1	0
plastoquinone	low	1	0
cysteine	low	3	0
phosphorus	low	1	0
monoaminocarboxydihydroborane	low	1	0
dolichols	low	1	0
bafilomycin a1	low	1	0
emerin	low	9	0
l 744832	low	1	0
abt-100	low	3	0
ursodoxicoltaurine	low	1	0
arl-67156	low	1	0
abt-737	low	1	0
rm-493	low	1	0
dihydrotachysterol	low	19	0
acid phosphatase	low	2	0
nad	low	4	0
cytochrome c-t	low	1	0
glucagon	low	2	0
neuropeptide y	low	1	0
oligonucleotides	low	1	0
phosphatidylcholines	low	1	0
sodium nitrite	low	1	0
sodium ethylxanthate	low	1	0
s-adenosylmethionine	low	1	0
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene	low	2	0
baricitinib	low	4	0
piperidines	medium	27	3
interleukin-8	low	1	0
bix 01294	low	1	0
2-oxohistidine	low	1	0
chondroitin	low	3	0
ascorbic acid	low	1	0
warfarin	low	1	0
epidermal growth factor	low	3	0
transforming growth factor beta	low	7	0
fti 277	low	3	0
ap20187	low	1	0
nitrophenols	low	1	0
apyrase	low	1	0
thromboplastin	low	2	0
chondroitin sulfates	low	3	0
folic acid	low	1	0
allopurinol	low	1	0
eye	low	6	0
phosphorus radioisotopes	low	1	0
leptin	low	3	0

Protein Targets (2,266)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	28	0	0	28
thioredoxin reductase	31	0	0	31
ATAD5 protein, partial	25	0	0	25
GLS protein	16	0	0	16
TDP1 protein	55	0	0	55
regulator of G-protein signaling 4	17	0	0	17
67.9K protein	17	0	0	17
Parkin	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
IDH1	20	0	0	20
euchromatic histone-lysine N-methyltransferase 2	43	0	0	43
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	16
huntingtin isoform 2	7	0	0	7
ras-related protein Rab-9A	7	0	0	7
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
survival motor neuron protein isoform d	22	0	0	22
D(1A) dopamine receptor	5	0	0	5
Ataxin-2	30	0	0	30
ATP-dependent phosphofructokinase	17	0	0	17
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	4	0	0	4
USP1 protein, partial	31	0	0	31
vitamin D3 receptor isoform VDRA	17	0	0	17
importin subunit beta-1 isoform 1	7	0	0	7
flap endonuclease 1	14	0	0	14
serine/threonine-protein kinase PLK1	6	0	0	6
snurportin-1	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
GTP-binding nuclear protein Ran isoform 1	6	0	0	6
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	20	0	0	20
geminin	46	0	0	46
DNA polymerase kappa isoform 1	17	0	0	17
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	3	3	6
Beta-lactamase	0	3	0	3
Transthyretin	0	1	3	6
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	3	1	4
Cyclin-A2	0	2	0	2
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	4	7	11
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	3	3	6
Guanine nucleotide-binding protein G	7	0	0	7
Fatty acid-binding protein 5	0	1	1	2
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	3	7	10
Mitogen-activated protein kinase 14	0	6	8	14
Heat shock protein HSP 90-alpha	0	3	4	8
Botulinum neurotoxin type A	0	2	0	2
Neutrophil cytosol factor 1	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	18	0	0	18
RAR-related orphan receptor gamma	40	0	0	40
GLI family zinc finger 3	39	0	0	39
AR protein	55	0	0	55
aldehyde dehydrogenase 1 family, member A1	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	43	0	0	43
retinoid X nuclear receptor alpha	37	0	0	37
estrogen nuclear receptor alpha	63	0	0	63
peroxisome proliferator-activated receptor delta	28	0	0	28
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	34	0	0	34
activating transcription factor 6	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
Histone H2A.x	18	0	0	18
thyroid hormone receptor beta isoform a	17	0	0	17
heat shock protein beta-1	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 1	37	0	0	37
lamin isoform A-delta10	29	0	0	29
Voltage-dependent calcium channel gamma-2 subunit	28	0	0	28
Glutamate receptor 2	28	2	1	31
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
Glutamate receptor ionotropic, NMDA 1	0	8	3	15
Glutamate receptor ionotropic, NMDA 2A	0	6	3	13
Glutamate receptor ionotropic, NMDA 2B	0	6	3	13
Glutamate receptor ionotropic, NMDA 2C	0	6	3	13
Uracil nucleotide/cysteinyl leukotriene receptor	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	6	3	13
Glutamate receptor ionotropic, NMDA 3B	0	6	3	13
Glutamate receptor ionotropic, NMDA 3A	0	6	3	13
Ephrin type-A receptor 1	0	0	7	7
Histamine H1 receptor	0	1	0	1
Beta-adrenergic receptor kinase 2	0	0	1	1
Cyclin-dependent kinase 7	0	0	7	7
Calcium/calmodulin-dependent protein kinase type 1B	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	5	5
Aurora kinase B	0	2	7	9
Homeodomain-interacting protein kinase 2	0	0	3	3
Chain A, Apoptosis regulator Bcl-X	0	1	0	1
PPM1D protein	19	0	0	19
EWS/FLI fusion protein	29	0	0	30
Bcl-2-like protein 11	0	1	0	1
Interferon beta	38	0	0	38
Beta-casein	0	1	0	1
Apoptosis regulator Bcl-2	0	3	2	5
Alpha-1B adrenergic receptor	0	12	1	13
Alpha-2B adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	2	1	3
Alpha-2A adrenergic receptor	0	2	1	3
Adenosine receptor A2a	0	7	1	11
BH3-interacting domain death agonist	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog	0	0	1	1
Apoptosis regulator BAX	0	1	0	1
Bcl-2-like protein 1	0	4	2	6
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Bcl-2-related protein A1	0	1	1	2
Bcl-2 homologous antagonist/killer	0	2	1	3
Bcl-2-like protein 2	0	2	0	2
Bcl2-associated agonist of cell death	0	1	0	1
Bcl-2-binding component 3, isoforms 1/2	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Microtubule-associated protein tau	25	0	0	25
Smad3	14	0	0	14
thyroid stimulating hormone receptor	18	0	0	18
nuclear receptor subfamily 1, group I, member 3	32	0	0	32
progesterone receptor	30	0	0	30
estrogen-related nuclear receptor alpha	44	0	0	44
peroxisome proliferator activated receptor gamma	40	0	0	40
aryl hydrocarbon receptor	22	0	0	22
chromobox protein homolog 1	25	0	0	25
thyroid hormone receptor beta isoform 2	41	0	0	41
peripheral myelin protein 22	28	0	0	28
cytochrome P450 3A4 isoform 1	20	0	0	20
Gamma-aminobutyric acid receptor subunit pi	20	2	3	25
ATP-binding cassette sub-family C member 3	0	31	0	31
Multidrug resistance-associated protein 4	0	32	0	34
Solute carrier family 22 member 6	0	6	0	6
Carbonic anhydrase 12	0	8	0	11
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	5	0	7
Bile salt export pump	0	45	0	47
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	19	0	27
Carbonic anhydrase 2	0	19	0	27
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	6	2	9
Cytochrome P450 1A2	0	11	1	15
Prostaglandin G/H synthase 1	0	3	1	4
Carbonic anhydrase 3	0	7	0	10
Cytochrome P450 3A4	0	20	1	25
Cytochrome P450 2D6	0	10	1	12
Cytochrome P450 2C9	0	20	1	22
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	20	2	3	25
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	20	2	3	25
Gamma-aminobutyric acid receptor subunit gamma-2	20	2	3	25
UDP-glucuronosyltransferase 1-6	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	20	2	3	25
Gamma-aminobutyric acid receptor subunit alpha-3	20	2	3	25
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	5
Carbonic anhydrase 4	0	14	0	17
Prostaglandin G/H synthase 1	0	5	0	5
Carbonic anhydrase 6	0	8	0	11
Gamma-aminobutyric acid receptor subunit gamma-1	20	2	3	25
Gamma-aminobutyric acid receptor subunit alpha-2	20	2	3	25
Gamma-aminobutyric acid receptor subunit alpha-4	20	2	3	25
Gamma-aminobutyric acid receptor subunit gamma-3	20	2	3	25
Gamma-aminobutyric acid receptor subunit alpha-6	20	2	3	25
Carbonic anhydrase 5A, mitochondrial	0	10	0	13
Prostaglandin G/H synthase 2	0	7	2	10
Carbonic anhydrase 7	0	8	0	11
Nuclear receptor ROR-gamma	12	1	1	14
Cytochrome P450 2J2	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	20	2	3	25
Gamma-aminobutyric acid receptor subunit beta-3	20	2	3	25
Gamma-aminobutyric acid receptor subunit beta-2	20	2	3	25
Carbonic anhydrase 9	0	10	0	13
GABA theta subunit	20	2	3	25
Canalicular multispecific organic anion transporter 1	0	31	0	32
Carbonic anhydrase 15	0	9	0	12
Carbonic anhydrase 13	0	5	0	7
Gamma-aminobutyric acid receptor subunit epsilon	20	2	3	25
Carbonic anhydrase 14	0	8	0	11
Carbonic anhydrase 5B, mitochondrial	0	8	0	11
toxin B	0	0	0	1
N-alpha-acetyltransferase 50	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	13	0	0	13
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	9	0	0	9
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	19	0	0	19
NFKB1 protein, partial	7	0	0	7
Thrombopoietin	7	0	0	7
glucocorticoid receptor [Homo sapiens]	45	0	0	45
farnesoid X nuclear receptor	28	0	0	28
vitamin D (1,25- dihydroxyvitamin D3) receptor	28	0	0	28
arylsulfatase A	16	0	0	16
Bloom syndrome protein isoform 1	19	0	0	19
D(1A) dopamine receptor	8	0	0	8
muscarinic acetylcholine receptor M1	12	0	0	12
Histone deacetylase 3	0	5	0	7
Histone deacetylase 4	0	4	1	8
Histone deacetylase 1	0	7	2	11
Histone deacetylase 7	0	4	0	6
Histone deacetylase 2	0	7	1	10
Polyamine deacetylase HDAC10	0	4	0	6
Histone deacetylase 11	0	4	0	6
Histone deacetylase 8	0	6	0	8
Histone deacetylase 6	0	6	1	9
Histone deacetylase 9	0	4	0	6
Histone deacetylase 5	0	4	0	6
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	30	0	0	30
pregnane X nuclear receptor	39	0	0	39
tumor susceptibility gene 101 protein	4	0	0	4
Cyclin-dependent kinase 1	0	2	5	7
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	5	0	5
TAR DNA-binding protein 43	8	0	0	8
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	2	4
ATPase family AAA domain-containing protein 5	23	0	0	23
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
NPYLR7B	0	0	3	3
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	12	0	0	12
nuclear receptor ROR-gamma isoform 1	22	0	0	22
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	4	0	4
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
Sodium/nucleoside cotransporter 2	0	4	0	4
Rap guanine nucleotide exchange factor 3	7	0	0	7
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	8	6	14
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	4	2	6
Insulin receptor	0	1	6	8
Phosphoglycerate kinase 2	0	1	0	1
Platelet-derived growth factor receptor beta	0	2	6	9
Adenosine receptor A3	0	14	3	18
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	2	6	9
Inosine-5'-monophosphate dehydrogenase 2	0	1	5	6
Endoplasmin	0	2	2	5
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	2	3
Fibroblast growth factor receptor 4	0	0	2	3
Fibroblast growth factor receptor 3	0	0	2	3
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	2	1	6
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	7	4	13
Adenosine receptor A2b	0	0	1	3
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	13	2	17
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	5	6
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	4	0	4
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	6	0	6
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	4	0	4
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	2	7
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	4	0	4
Mu-type opioid receptor	0	1	2	3
Delta-type opioid receptor	0	4	2	6
Kappa-type opioid receptor	0	1	2	3
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	1	1	2
Inositol monophosphatase 1	10	0	0	10
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	17	0	0	17
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	3
Proton-coupled amino acid transporter 1	0	5	0	6
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	3
interleukin 8	9	0	0	9
estrogen receptor 2 (ER beta)	25	0	0	25
transcriptional regulator ERG isoform 3	4	0	0	4
Polyphenol oxidase 2	0	5	0	8
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	43	0	0	43
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	5	1	8
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Thromboxane-A synthase	0	3	0	3
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	3	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Chain A, Ferritin light chain	19	0	0	19
G	21	0	0	21
cytochrome P450 2D6	17	0	0	17
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Potassium channel subfamily K member 2	0	1	3	4
HLA class I histocompatibility antigen, B alpha chain	21	0	0	21
ATP-dependent translocase ABCB1	0	16	2	23
Alpha-2A adrenergic receptor	0	6	2	9
Alpha-2C adrenergic receptor	0	6	2	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Alpha-1D adrenergic receptor	0	3	1	5
Alpha-1A adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	1	1	3
5-hydroxytryptamine receptor 6	0	4	1	5
Spike glycoprotein	17	1	4	22
Sodium-dependent dopamine transporter	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	8
Potassium channel subfamily K member 2	0	2	0	2
Inositol hexakisphosphate kinase 1	21	0	0	21
cytochrome P450 2C9, partial	21	0	0	21
glucocerebrosidase	8	0	0	8
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	2	6
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	5	4	11
Type-2 angiotensin II receptor	0	4	0	4
Type-2 angiotensin II receptor	0	3	0	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
alpha-galactosidase	2	0	0	2
cytochrome P450 2C19 precursor	7	0	0	7
lethal factor (plasmid)	12	0	0	12
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Monoglyceride lipase	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	4
Alpha-2B adrenergic receptor	0	5	2	8
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	3	0	3
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	6
Amino acid transporter	0	3	0	3
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
V-type proton ATPase subunit S1	0	1	0	1
Vacuolar proton pump subunit B	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	6	6
Membrane-associated progesterone receptor component 1	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	6	6
ATP-dependent RNA helicase DDX3X	0	0	5	5
Pyridoxal kinase	0	0	5	5
Citron Rho-interacting kinase	0	1	6	7
Serine/threonine-protein kinase Chk1	0	0	6	6
Aurora kinase A	0	1	6	7
Cyclin-G-associated kinase	0	2	6	8
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 2	0	3	6	9
Dynamin-like 120 kDa protein, mitochondrial	0	0	5	5
Tyrosine-protein kinase JAK2	0	1	3	5
Eukaryotic translation initiation factor 5B	0	0	5	5
Rho-associated protein kinase 2	0	4	6	10
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	2	6	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	5	5
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	1	7	8
Structural maintenance of chromosomes protein 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	0	6	6
Tyrosine-protein kinase ABL1	0	7	8	17
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	5	5
Protein kinase C beta type	0	2	6	8
Tyrosine-protein kinase Lck	0	6	6	12
Tyrosine-protein kinase Fyn	0	3	6	9
Glycogen phosphorylase, liver form	0	1	5	6
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Adenine phosphoribosyltransferase	0	0	5	5
Tyrosine-protein kinase Yes	0	2	6	8
Tyrosine-protein kinase Lyn	0	1	6	7
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	6	8
Insulin-like growth factor 1 receptor	0	2	6	8
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	5	5
Hepatocyte growth factor receptor	0	1	6	7
Tyrosine-protein kinase HCK	0	2	6	8
Serine/threonine-protein kinase A-Raf	0	0	5	5
Glycogen phosphorylase, brain form	0	0	5	5
Breakpoint cluster region protein	0	3	7	12
Serine/threonine-protein kinase pim-1	0	1	7	8
DNA topoisomerase 2-alpha	0	2	5	12
Cyclin-dependent kinase 4	0	1	6	7
ADP/ATP translocase 3	0	0	5	5
Proto-oncogene tyrosine-protein kinase Src	0	6	6	12
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	5	5
Serine/threonine-protein kinase B-raf	0	2	6	8
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	6	7	13
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	3	7	11
cAMP-dependent protein kinase catalytic subunit alpha	0	4	6	10
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	5	5
Casein kinase II subunit alpha'	0	4	6	10
Ras-related protein Rab-6A	0	0	5	5
Multifunctional protein ADE2	0	0	5	5
cAMP-dependent protein kinase catalytic subunit gamma	0	4	4	8
cAMP-dependent protein kinase catalytic subunit beta	0	4	6	10
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	6	6
Tyrosine-protein kinase JAK1	0	1	6	8
Beta-adrenergic receptor kinase 1	0	0	5	5
Probable ATP-dependent RNA helicase DDX6	0	0	5	5
Mitogen-activated protein kinase 3	0	0	6	6
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Deoxycytidine kinase	0	0	5	5
Mitogen-activated protein kinase 1	0	2	6	8
Ephrin type-A receptor 2	0	1	6	7
Ephrin type-B receptor 2	0	2	6	8
Non-receptor tyrosine-protein kinase TYK2	0	1	6	8
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	5	5
S-adenosylmethionine synthase isoform type-2	0	0	5	5
DnaJ homolog subfamily A member 1	0	0	5	5
RAC-alpha serine/threonine-protein kinase	0	2	6	8
RAC-beta serine/threonine-protein kinase	0	1	6	7
DNA replication licensing factor MCM4	0	0	5	5
Myosin-10	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 2	0	2	6	8
Receptor-type tyrosine-protein kinase FLT3	0	2	6	8
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	1	6	7
Serine/threonine-protein kinase receptor R3	0	0	4	4
TGF-beta receptor type-2	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	5	5
Tyrosine-protein kinase CSK	0	1	6	7
Glycine--tRNA ligase	0	0	5	5
Protein kinase C iota type	0	1	7	8
Exosome RNA helicase MTR4	0	0	5	5
Tyrosine-protein kinase Tec	0	1	6	7
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase SYK	0	2	7	9
26S proteasome regulatory subunit 6B	0	1	5	6
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	1	6	7
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Casein kinase I isoform alpha	0	1	6	7
Casein kinase I isoform delta	0	1	6	7
MAP kinase-activated protein kinase 2	0	1	6	7
Elongation factor Tu, mitochondrial	0	0	5	5
Cysteine--tRNA ligase, cytoplasmic	0	0	5	5
Casein kinase I isoform epsilon	0	1	6	7
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	5	5
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	6	6
Dual specificity protein kinase CLK3	0	0	6	6
Glycogen synthase kinase-3 alpha	0	1	6	7
Glycogen synthase kinase-3 beta	0	2	6	8
Cyclin-dependent kinase 9	0	0	6	6
Ras-related protein Rab-27A	0	0	5	5
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Ribosomal protein S6 kinase alpha-3	0	1	6	7
Serine/threonine-protein kinase Nek2	0	1	6	7
Serine/threonine-protein kinase Nek3	0	0	6	6
Tyrosine-protein kinase JAK3	0	1	2	4
Dual specificity mitogen-activated protein kinase kinase 6	0	0	6	6
LIM domain kinase 1	0	1	6	7
LIM domain kinase 2	0	1	6	7
Mitogen-activated protein kinase 10	0	3	6	9
Tyrosine--tRNA ligase, cytoplasmic	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-1	0	0	5	6
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	1	6	7
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	5	5
Ras-related protein Rab-10	0	0	5	5
Actin-related protein 3	0	0	5	5
Actin-related protein 2	0	0	5	5
GTP-binding nuclear protein Ran	0	0	5	5
Casein kinase I isoform gamma-2	0	0	6	6
Cyclin-dependent kinase 3	0	0	5	5
Cyclin-dependent kinase 6	0	1	5	6
Cyclin-dependent-like kinase 5	0	1	6	7
Cyclin-dependent kinase 16	0	0	6	6
Cyclin-dependent kinase 17	0	0	6	6
ATP-dependent 6-phosphofructokinase, platelet type	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 1	0	4	6	10
DNA topoisomerase 2-beta	0	1	6	13
Protein kinase C theta type	0	1	7	8
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	0	6	6
Focal adhesion kinase 1	0	2	6	8
Protein kinase C delta type	0	3	7	10
Tyrosine-protein kinase BTK	0	2	6	8
Activated CDC42 kinase 1	0	1	6	7
Epithelial discoidin domain-containing receptor 1	0	3	6	9
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
Integrin-linked protein kinase	0	0	5	5
Rho-associated protein kinase 1	0	4	6	10
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Serine/threonine-protein kinase ATR	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	6	7
Activin receptor type-2B	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	1	6	7
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	0	6	6
Structural maintenance of chromosomes protein 1A	0	0	5	5
Chromodomain-helicase-DNA-binding protein 4	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 1	0	0	5	5
Ephrin type-A receptor 7	0	0	5	5
Delta(24)-sterol reductase	0	0	5	5
Ribosomal protein S6 kinase alpha-1	0	2	6	8
Dual specificity testis-specific protein kinase 1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	3	6	9
Serine/threonine-protein kinase STK11	0	0	6	6
Serine/threonine-protein kinase N1	0	2	6	8
Serine/threonine-protein kinase N2	0	2	6	8
Calcium/calmodulin-dependent protein kinase type IV	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	2	6	8
AP2-associated protein kinase 1	0	1	6	7
Myosin light chain kinase 3	0	0	6	6
Uncharacterized aarF domain-containing protein kinase 5	0	0	4	4
Putative heat shock protein HSP 90-beta 2	0	0	5	5
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	5	5
Serine/threonine-protein kinase ULK3	0	0	6	6
Uncharacterized protein FLJ45252	0	0	5	5
Acyl-CoA dehydrogenase family member 11	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	5	5
Serine/threonine-protein kinase MARK2	0	0	6	6
ATP-dependent RNA helicase DHX30	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	5	5
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	5	5
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
MAP kinase-activated protein kinase 5	0	0	5	5
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	4	4
Misshapen-like kinase 1	0	0	4	4
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
ATP-dependent RNA helicase DDX1	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Serine/threonine-protein kinase Nek1	0	0	6	6
PAS domain-containing serine/threonine-protein kinase	0	0	5	5
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	5	5
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	6	8
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Nucleolar GTP-binding protein 1	0	0	5	5
Serine/threonine-protein kinase D2	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	5	5
RNA cytidine acetyltransferase	0	0	5	5
Serine/threonine-protein kinase SIK2	0	1	6	7
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
dCTP pyrophosphatase 1	0	0	5	5
Dual specificity protein kinase CLK4	0	0	6	6
Casein kinase I isoform gamma-1	0	0	6	6
Serine/threonine-protein kinase PAK 6	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	5	5
Isoleucine--tRNA ligase, mitochondrial	0	0	3	3
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	5	5
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Mitogen-activated protein kinase kinase kinase 20	0	0	6	6
Cyclin-dependent kinase 12	0	0	5	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase 26	0	0	6	6
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	1	6	7
5'-AMP-activated protein kinase subunit gamma-2	0	0	5	6
Serine/threonine-protein kinase TBK1	0	0	6	6
Septin-9	0	0	5	5
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	1	6	7
Serine/threonine-protein kinase TAO2	0	0	6	6
Long-chain-fatty-acid--CoA ligase 5	0	0	4	4
Serine/threonine-protein kinase ICK	0	0	4	4
RAC-gamma serine/threonine-protein kinase	0	1	6	7
Serine/threonine-protein kinase 38-like	0	0	3	3
Serine/threonine-protein kinase SIK3	0	1	6	7
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	0	5	5
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Serine/threonine-protein kinase 24	0	0	4	4
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
Proteasome subunit beta type-11	0	2	0	2
Fumarate hydratase	19	0	0	19
polyprotein	19	0	0	19
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	2	0	2
Cathepsin B	0	2	0	2
Replicase polyprotein 1ab	0	6	5	11
Replicase polyprotein 1ab	0	8	5	13
Aromatase	0	8	0	8
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit beta type-1	0	3	0	4
Proteasome subunit alpha type-1	0	2	0	2
Proteasome subunit alpha type-2	0	2	0	2
Proteasome subunit alpha type-3	0	2	0	2
Proteasome subunit alpha type-4	0	2	0	2
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	2	0	2
Proteasome subunit beta type-9	0	2	0	2
Proteasome subunit alpha type-5	0	2	0	2
Proteasome subunit beta type-4	0	2	0	2
Proteasome subunit beta type-6	0	2	0	2
Proteasome subunit beta type-5	0	6	0	7
Proteasome subunit beta type-10	0	2	0	2
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	2	0	2
Proteasome subunit beta type-2	0	3	0	4
Proteasome subunit alpha type-6	0	2	0	2
Proteasome subunit alpha-type 8	0	2	0	2
Proteasome subunit beta type-7	0	2	0	2
Gamma-secretase subunit PEN-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
cytochrome P450 2D6 isoform 1	8	0	0	8
Telomerase reverse transcriptase	0	1	0	1
Acetylcholinesterase	0	4	0	4
Lysine-specific histone demethylase 1A	0	4	0	4
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Cholinesterase	0	4	0	4
Tyrosine-protein phosphatase non-receptor type 1	0	5	0	7
Acetylcholinesterase	0	8	0	8
Aldo-keto reductase family 1 member C3	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Aldo-keto reductase family 1 member C2	0	1	0	1
Cholinesterase	0	5	0	5
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
Cytochrome P450 1B1	0	8	1	9
GTPase HRas	0	2	0	3
GTPase KRas	0	1	0	2
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	4	0	4
Protein farnesyltransferase subunit beta	0	4	0	4
Geranylgeranyl transferase type-1 subunit beta	0	4	0	4
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
caspase 7, apoptosis-related cysteine protease	13	0	0	13
caspase-3	13	0	0	13
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	2	3	6
Chymotrypsinogen A	0	3	0	3
Neutrophil elastase	0	5	0	5
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Chymase	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	2	0	2
Transcription factor p65	0	2	0	2
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	3	0	5
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
cellular tumor antigen p53 isoform a	7	0	0	7
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	3	0	5
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	12	0	0	12
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	4	0	4
Vitamin D3 receptor	0	3	3	10
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	5	7
Cytochrome P450 2C19	0	10	1	11
Kappa-type opioid receptor	0	1	1	3
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Chain A, serum paraoxonase	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
endonuclease IV	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
peripheral myelin protein 22 isoform 1	10	0	0	10
Serine/threonine-protein kinase Sgk1	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit beta	0	4	0	4
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	4	2	6
Cyclin-A1	0	1	0	1
Casein kinase II subunit alpha 3	0	4	0	4
Single-stranded DNA cytosine deaminase	2	0	0	2
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9	0	0	9
thyrotropin-releasing hormone receptor	5	0	0	5
Caspase-2	0	0	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	3	0	4
30S ribosomal protein S7	0	3	0	4
50S ribosomal protein L15	0	3	0	4
50S ribosomal protein L10	0	3	0	4
50S ribosomal protein L11	0	3	0	4
50S ribosomal protein L7/L12	0	3	0	4
50S ribosomal protein L19	0	3	0	4
50S ribosomal protein L1	0	3	0	4
50S ribosomal protein L20	0	3	0	4
50S ribosomal protein L27	0	3	0	4
50S ribosomal protein L28	0	3	0	4
50S ribosomal protein L29	0	3	0	4
50S ribosomal protein L31	0	3	0	4
50S ribosomal protein L31 type B	0	3	0	4
50S ribosomal protein L32	0	3	0	4
50S ribosomal protein L33	0	3	0	4
50S ribosomal protein L34	0	3	0	4
50S ribosomal protein L35	0	3	0	4
50S ribosomal protein L36	0	3	0	4
30S ribosomal protein S10	0	3	0	4
30S ribosomal protein S11	0	3	0	4
30S ribosomal protein S12	0	3	0	4
30S ribosomal protein S13	0	3	0	4
30S ribosomal protein S16	0	3	0	4
30S ribosomal protein S18	0	3	0	4
30S ribosomal protein S19	0	3	0	4
30S ribosomal protein S20	0	3	0	4
30S ribosomal protein S2	0	3	0	4
30S ribosomal protein S3	0	3	0	4
30S ribosomal protein S4	0	3	0	4
30S ribosomal protein S5	0	3	0	4
30S ribosomal protein S8	0	3	0	4
30S ribosomal protein S9	0	3	0	4
50S ribosomal protein L13	0	3	0	4
50S ribosomal protein L14	0	3	0	4
50S ribosomal protein L16	0	3	0	4
50S ribosomal protein L23	0	3	0	4
30S ribosomal protein S15	0	3	0	4
50S ribosomal protein L17	0	3	0	4
50S ribosomal protein L21	0	3	0	4
50S ribosomal protein L30	0	3	0	4
50S ribosomal protein L6	0	3	0	4
30S ribosomal protein S14	0	3	0	4
30S ribosomal protein S17	0	3	0	4
30S ribosomal protein S1	0	3	0	4
50S ribosomal protein L18	0	3	0	4
50S ribosomal protein L2	0	3	0	4
50S ribosomal protein L3	0	3	0	4
50S ribosomal protein L24	0	3	0	4
50S ribosomal protein L4	0	3	0	4
50S ribosomal protein L22	0	3	0	4
50S ribosomal protein L5	0	3	0	4
30S ribosomal protein S21	0	3	0	4
50S ribosomal protein L25	0	3	0	4
50S ribosomal protein L36 2	0	3	0	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase	0	7	0	10
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	4	5
Replicase polyprotein 1ab	0	1	4	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	4	5
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	2	2
Amyloid-beta precursor protein	1	7	1	10
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	1	4	5
Muscarinic acetylcholine receptor M2	0	4	1	6
Muscarinic acetylcholine receptor M4	0	3	0	4
Muscarinic acetylcholine receptor M5	0	3	0	4
Replicase polyprotein 1a	0	1	4	5
Replicase polyprotein 1ab	0	1	4	5
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	6	1	8
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	4	1	6
Serine/threonine-protein kinase mTOR	0	5	4	9
Beta-secretase 1	0	4	0	4
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	2	0	2
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Angiotensin-converting enzyme 2	0	1	4	5
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, Cruzipain	9	0	0	9
Luciferase	17	0	0	17
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	12	0	0	12
60 kDa chaperonin	0	5	0	5
60 kDa heat shock protein, mitochondrial	0	5	0	5
Glycine receptor subunit alpha-1	0	0	2	2
10 kDa heat shock protein, mitochondrial	0	5	0	5
Thiosulfate sulfurtransferase	0	5	0	5
60 kDa chaperonin	0	5	0	5
10 kDa chaperonin	0	5	0	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	3	0	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	3	0	5
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	1	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	2	0	0	2
alkaline phosphatase, intestinal	0	1	0	1
apical membrane antigen 1, AMA1	3	0	0	3
PINK1	2	0	0	2
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
thyroid stimulating hormone receptor	15	0	0	15
lysosomal alpha-glucosidase preproprotein	5	0	0	5
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
perilipin-5	0	2	0	2
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
pyruvate kinase PKM isoform a	2	0	0	2
DNA polymerase beta	5	0	0	5
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	1	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
muscleblind-like protein 1 isoform 1	9	0	0	9
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
neuropeptide S receptor isoform A	7	0	0	7
Prostaglandin E synthase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	1	0	10
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	1	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Integrin beta-3	5	2	1	8
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	2
Heme oxygenase 1	0	1	0	1
Integrin alpha-IIb	5	1	1	7
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Microtubule-associated protein tau	0	2	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	3	0	3
Aminopeptidase N	0	2	0	2
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Amine oxidase [flavin-containing] A	0	6	0	6
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	5	1	6
Amine oxidase [flavin-containing] B	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Alpha-synuclein	4	4	1	9
Alpha-1A adrenergic receptor	0	11	1	12
Histamine H2 receptor	10	1	0	11
Caspase-7	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	2	2	4
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	1	4	8
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	1	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	1	12
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Leukotriene C4 synthase	0	0	2	2
GALC protein	4	0	0	4
tyrosine-protein kinase Yes	3	0	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	2	3
Serine/threonine-protein kinase 25	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	2	4
Peripheral plasma membrane protein CASK	0	0	2	2
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	2	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
NUAK family SNF1-like kinase 1	0	1	2	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	2	2
Cyclin-dependent kinase 14	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	2	2
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
RAF proto-oncogene serine/threonine-protein kinase	0	2	2	4
High affinity nerve growth factor receptor	0	0	5	5
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Macrophage colony-stimulating factor 1 receptor	0	2	2	4
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	5	5
Quinolone resistance protein NorA	0	2	0	2
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Mast/stem cell growth factor receptor Kit	0	2	3	5
Cytochrome P450 2A6	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	2	2
Angiotensin-converting enzyme	0	3	0	3
Insulin receptor-related protein	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Platelet-derived growth factor receptor alpha	0	3	3	6
Tyrosine-protein kinase Blk	0	1	0	1
Vascular endothelial growth factor receptor 1	0	0	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	2	2
Cytochrome P450 2B6	0	1	0	1
Cyclin-dependent kinase 11B	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	0	2	2
Protein kinase C eta type	0	1	3	4
Activin receptor type-2A	0	0	2	2
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Leukocyte tyrosine kinase receptor	0	0	2	2
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	5	5
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	0	2	2
Vascular endothelial growth factor receptor 2	0	2	2	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	2	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase ZAP-70	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	2	4
Cyclin-dependent kinase 8	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	4	4
Tyrosine-protein kinase Blk	0	1	2	3
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	2	2
Serine/threonine-protein kinase PLK1	0	1	5	6
Death-associated protein kinase 1	0	1	2	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	3
Ephrin type-B receptor 1	0	0	2	2
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	2	2	4
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Cell division control protein 2 homolog	0	0	2	2
Calcium-dependent protein kinase 1	0	0	2	2
Tubulin alpha-1A chain	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Protein kinase C epsilon type	0	3	3	6
Angiopoietin-1 receptor	0	1	2	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Protein kinase C zeta type	0	2	4	6
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Myotonin-protein kinase	0	2	2	4
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	1	3	4
cGMP-dependent protein kinase 2	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	4	0	4
Serine/threonine-protein kinase D1	0	1	3	4
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	0	2	2
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	4	4
Breakpoint cluster region protein	0	1	0	1
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Cyclin-dependent kinase 15	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	4	4
SRSF protein kinase 1	0	0	2	2
Protein cereblon	0	2	1	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	1	2	3
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	1	2	3
Serine/threonine-protein kinase 32B	0	0	2	2
Serine/threonine-protein kinase PLK2	0	0	2	2
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
ALK tyrosine kinase receptor	0	1	2	3
SRSF protein kinase 3	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	3	3
NF-kappa-B essential modulator	0	1	0	1
PAX8	0	0	0	1
nuclear receptor subfamily 0 group B member 1	0	2	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
steroidogenic factor 1	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Tubulin beta-2B chain	0	4	1	8
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Ornithine transcarbamylase, mitochondrial	0	1	0	1
Farnesyl pyrophosphate synthase	0	4	1	5
Nociceptin receptor	0	2	0	2
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	3	0	0	3
nonstructural protein 1	7	0	0	7
LANA	0	0	0	1
serine-protein kinase ATM isoform a	3	0	0	3
cytochrome P450 2C9 precursor	6	0	0	6
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
eyes absent homolog 2 isoform a	3	0	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	6	0	0	6
Multidrug and toxin extrusion protein 1	0	3	0	3
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
glp-1 receptor, partial	12	0	0	12
LMP1 [Human herpesvirus 4]	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	2	0	2
DNA topoisomerase 1	0	2	0	3
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Integrase	0	2	0	2
Similar to alpha-tubulin isoform 1	0	3	1	7
Similar to alpha-tubulin isoform 1	0	3	0	6
Solute carrier organic anion transporter family member 1B3	0	8	0	9
Cell division cycle 7-related protein kinase	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Regulatory-associated protein of mTOR	0	2	0	2
Target of rapamycin complex subunit LST8	0	2	0	2
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	2	0	2
Chain B, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	0	0	0	1
serine/threonine-protein kinase 33 isoform a	0	0	1	2
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
C-C motif chemokine 2	0	2	0	2
C-C chemokine receptor type 2	0	3	0	3
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Rho-associated protein kinase 2	0	2	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	3	0	0	3
Solute carrier family 22 member 8	0	1	0	3
Thymidylate synthase	0	2	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	3	0	4
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	3	0	3
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	3	0	3
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	2	3
Protein farnesyltransferase subunit beta	0	1	2	3
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	9	0	10
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Glutathione reductase	0	1	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	6	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	1	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	1	0	4
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase	0	0	0	3
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 3A5	0	1	0	2
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
5-hydroxytryptamine receptor 2B	0	10	1	11
Cellular retinoic acid-binding protein 1	0	0	2	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
Chain A, Protein farnesyltransferase alpha subunit	0	1	0	1
Chain B, Protein farnesyltransferase beta subunit	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	2	0	2
Protein farnesyltransferase alpha subunit	0	2	0	2
CAAX farnesyltransferase subunit beta	0	2	0	2
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Albumin	0	2	3	7
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	3	1	4
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	1	0	1
Protease	0	2	2	4
Neprilysin	0	1	0	1
5-hydroxytryptamine receptor 1A	0	6	1	9
Thromboxane A2 receptor	0	1	0	2
Type-1 angiotensin II receptor	0	1	1	2
Squalene synthase	0	2	0	2
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	9	0	12
Chain A, Antigen Cd11a (p180)	0	1	0	1
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	9	0	9
Insulin receptor	0	2	0	2
Androgen receptor	0	5	0	5
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	8	2	10
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Lanosterol 14-alpha demethylase	0	2	0	2
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
ClpP	2	0	0	2
M-phase phosphoprotein 8	9	0	0	9
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	3	0	3
Cytochrome P450 2C11	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	3	0	3
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	2	0	0	2
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	5	0	0	5
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	2	2
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Cruzipain	0	1	0	1
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	2	2
phosphoglycerate kinase	2	0	0	2
Glucocorticoid receptor	0	4	1	10
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
Equilibrative nucleoside transporter 1	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
tumor necrosis factor	1	0	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
Phospholipase A2, membrane associated	0	1	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
5-hydroxytryptamine receptor 2C	0	6	1	7
Indoleamine 2,3-dioxygenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Leukotriene B4 receptor 1	0	0	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	4
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	2	1	3
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
Chain A, Glutathione-requiring prostaglandin D synthase	0	1	0	1
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Tubulin beta-3 chain	0	3	2	6
Tubulin beta-2A chain	0	2	2	5
Tubulin beta-8 chain	0	2	2	5
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Fatty-acid amide hydrolase 1	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Trypsin	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Fatty acid-binding protein, liver	0	0	1	1
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Coagulation factor VII	0	2	0	2
Sterol O-acyltransferase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Genome polyprotein	0	1	0	1
Integrin alpha-V	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	3
Cholecystokinin receptor type A	0	3	1	4
Melanocortin receptor 5	0	3	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
Beta-tubulin	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	3	0	3
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	2	0	4
Beta-lactamase VIM-1	0	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Hsf1 protein	0	0	2	3
Synaptic vesicle glycoprotein 2A	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
Solute carrier organic anion transporter family member 1A4	0	1	0	6
Solute carrier organic anion transporter family member 2B1	0	2	0	3
Solute carrier organic anion transporter family member 1A1	0	0	0	3
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	3	0	3
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	1	2
Beta-2 adrenergic receptor	0	2	0	3
Beta-3 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	1	2
Beta-1 adrenergic receptor	0	3	1	5
D(3) dopamine receptor	0	1	0	1
D(1A) dopamine receptor	0	1	1	2
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 1B	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Sodium-dependent serotonin transporter	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Puromycin-sensitive aminopeptidase	0	1	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	1	0	2
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Interstitial collagenase	0	1	1	2
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	1	1	2
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	2	0	2
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Vasopressin V2 receptor	0	1	0	1
Substance-P receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Collagenase 3	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Urease subunit beta	0	2	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Substance-K receptor	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Sialidase-2	0	1	0	1
N	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
Major prion protein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Histamine H2 receptor	0	2	0	2
Trypanothione reductase	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
P53	1	0	0	1
pyruvate kinase	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	2
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Myc proto-oncogene protein	0	1	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	1	2
DNA polymerase alpha catalytic subunit	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Tyrosinase	0	4	0	4
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	2
Endothelin receptor type B	1	0	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Endothelin-1 receptor	1	0	0	1
Cannabinoid receptor 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	4
Lysosomal alpha-glucosidase	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
large T antigen	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Melanocortin receptor 4	0	1	1	2
Melanocortin receptor 3	0	1	1	2
Melanocyte-stimulating hormone receptor	0	1	1	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Erk2	0	1	0	1
Mitogen-activated protein kinase 2	0	1	0	1
Protein kinase C gamma type	0	2	1	3
Cholesteryl ester transfer protein	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mitogen-activated protein kinase 14	0	1	1	2
Mitogen-activated protein kinase 1	0	1	0	1
P2X purinoceptor 7	0	1	0	1
P2X purinoceptor 7	0	1	0	1
Pyruvate kinase PKM	0	1	1	2
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Sulfate anion transporter 1	0	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Transcription regulator protein BACH1	0	1	0	1
Transcription factor MafK	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
NAD	0	0	0	1
Delta-type opioid receptor	0	0	0	1
Quinone oxidoreductase	0	0	0	3
Kelch-like ECH-associated protein 1	0	1	2	3
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Kelch-like ECH-associated protein 1	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	2	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Sodium/bile acid cotransporter	0	0	0	2
Ileal sodium/bile acid cotransporter	0	2	0	2
G-protein coupled bile acid receptor 1	0	0	2	2
Bile salt export pump	0	0	0	1
Ras guanyl-releasing protein 3	0	0	1	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain B, Protein farnesyltransferase beta subunit	0	1	0	1
Albumin	0	0	2	2
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
unnamed protein product	0	0	0	1
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Histone deacetylase 3	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase 2	0	1	0	1
Histone deacetylase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	0	2
Histone deacetylase 7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	1	2
Histone deacetylase 8	0	1	0	1
Histone deacetylase 11	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Histone deacetylase	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Chain A, Cytidine Deaminase	0	1	0	1
Cytidine deaminase	0	1	0	1
Uridine-cytidine kinase 1	0	0	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (336)

Protein Targets (2,266)

Progeria

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (336)

Drugs Studied (224)

Protein Targets (2,266)