Page last updated: 2024-10-30

khellin and Progeria

khellin has been researched along with Progeria in 4 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Progeria: An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

Research Excerpts

ExcerptRelevanceReference
" Other elastin deficiencies may be due to excess elastolysis or gene dosage effects."2.39Regulation of elastin synthesis in pathological states. ( Davidson, JM; Giro, MG; Zang, MC; Zoia, O, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zufferey, F1
Hadj-Rabia, S1
De Sandre-Giovannoli, A1
Dufier, JL1
Leheup, B1
Schweitze, C1
Bodemer, C1
Cormier-Daire, V1
Le Merrer, M1
Davidson, JM1
Zang, MC1
Zoia, O1
Giro, MG1
Jimbow, K1
Kobayashi, H1
Ishii, M1
Oyanagi, A1
Ooshima, A1
Lapiere, CH1

Reviews

2 reviews available for khellin and Progeria

ArticleYear
Regulation of elastin synthesis in pathological states.
    Ciba Foundation symposium, 1995, Volume: 192

    Topics: Animals; Cutis Laxa; Elastin; Fibrosis; Humans; Keloid; Progeria

1995
The molecular basis of connective tissue pathology.
    The British journal of dermatology, 1973, Volume: 89, Issue:1

    Topics: Animals; Basement Membrane; Cattle; Collagen; Connective Tissue; Ehlers-Danlos Syndrome; Elastin; Ep

1973

Other Studies

2 other studies available for khellin and Progeria

ArticleYear
Acro-osteolysis, keloid like-lesions, distinctive facial features, and overgrowth: two newly recognized patients with premature aging syndrome, Penttinen type.
    American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:7

    Topics: Acro-Osteolysis; Adolescent; Child; Collagen Type III; Face; Humans; Keloid; Lamin Type A; Limb Defo

2013
Scar and keloidlike lesions in progeria. An electron-microscopic and immunohistochemical study.
    Archives of dermatology, 1988, Volume: 124, Issue:8

    Topics: Biopsy; Child, Preschool; Cicatrix; Female; Humans; Immunohistochemistry; Keloid; Microscopy, Electr

1988