Page last updated: 2024-10-19

melatonin and Progeria

melatonin has been researched along with Progeria in 1 studies

Progeria: An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

Research Excerpts

ExcerptRelevanceReference
"Melatonin was shown to decrease the level of mRNA for AhR-dependent genes of CYP1A2 and CYP1B1 cytochromes in the retina, but had no effect on the content of mRNA for Nrf2-dependent genes in OXYS rats."1.40Expression of genes for AhR and Nrf2 signal pathways in the retina of OXYS rats during the development of retinopathy and melatonin-induced changes in this process. ( Grishanova, AY; Perepechaeva, ML; Stefanova, NA, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perepechaeva, ML1
Stefanova, NA1
Grishanova, AY1

Other Studies

1 other study available for melatonin and Progeria

ArticleYear
Expression of genes for AhR and Nrf2 signal pathways in the retina of OXYS rats during the development of retinopathy and melatonin-induced changes in this process.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:4

    Topics: Aging; Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Cytochrome P-450 CYP1A2;

2014