thymidine has been researched along with Progeria in 12 studies
Progeria: An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves for SM-C stimulation of thymidine incorporation were not significantly altered in aged or progeric cells." | 1.27 | Somatomedin C-binding and action in fibroblasts from aged and progeric subjects. ( Conover, CA; Dollar, LA; Hintz, RL; Rosenfeld, RG, 1985) |
| "Progeria is an autosomal recessive disorder showing precocious senility." | 1.25 | Progeria: a cell culture study on aging. ( Danes, BS, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Chen, S | 1 |
| Shan, H | 1 |
| Jia, Y | 1 |
| Chen, M | 1 |
| Song, Y | 1 |
| Lai, L | 1 |
| Li, Z | 1 |
| Sikora, E | 1 |
| Radziszewska, E | 1 |
| Kmieć, T | 1 |
| Maślińska, D | 1 |
| Vincent, RA | 1 |
| Huang, PC | 1 |
| Conover, CA | 1 |
| Dollar, LA | 1 |
| Rosenfeld, RG | 1 |
| Hintz, RL | 1 |
| Stachniak, JB | 1 |
| Sharp, ZD | 1 |
| Pool, TB | 1 |
| Cameron, IL | 1 |
| Albini, A | 1 |
| Pontz, B | 1 |
| Pulz, M | 1 |
| Allavena, G | 1 |
| Mensing, H | 1 |
| Müller, PK | 1 |
| Regan, JD | 1 |
| Setlow, RB | 1 |
| Epstein, J | 2 |
| Williams, JR | 2 |
| Little, JB | 2 |
| Danes, BS | 2 |
| Hopsu-Havu, VK | 1 |
| Tuohimaa, P | 1 |
12 other studies available for thymidine and Progeria
| Article | Year |
|---|---|
Efficient base editing with high precision in rabbits using YFE-BE4max.
Topics: Albinism; Animals; Base Sequence; Cytidine Deaminase; Cytosine; Disease Models, Animal; Embryo, Mamm | 2020 |
The impaired transcription factor AP-1 DNA binding activity in lymphocytes derived from subjects with some symptoms of premature aging.
Topics: Adolescent; Adult; Child; DNA; Down Syndrome; Electrophoresis; Humans; Lymphocyte Activation; Lympho | 1993 |
The proportion of cells labeled with tritiated thymidine as a function of population doubling level in cultures of fetal, adult, mutant, and tumor origin.
Topics: Cell Division; Cell Line; Cell Nucleus; Cells, Cultured; Fanconi Anemia; HeLa Cells; Mutation; Proge | 1976 |
Somatomedin C-binding and action in fibroblasts from aged and progeric subjects.
Topics: Adolescent; Adult; Aged; Aging; Carrier Proteins; Cell Division; Cells, Cultured; Child; DNA; Fibrob | 1985 |
Impaired proliferation response after PDGF induction in fibroblasts from Hutchinson-Guilford Progeria syndrome.
Topics: Autoradiography; Blood Platelets; Cell Division; Cell Line; Child; Epidermal Growth Factor; Female; | 1988 |
Decline of fibroblast chemotaxis with age of donor and cell passage number.
Topics: Aged; Aging; Cell Division; Cell Survival; Cells, Cultured; Chemotaxis; Child, Preschool; Collagen; | 1988 |
DNA repair in human progeroid cells.
Topics: Cell Line; Cell Survival; Centrifugation, Density Gradient; Cobalt Radioisotopes; DNA; DNA Repair; F | 1974 |
Rate of DNA repair in progeric and normal human fibroblasts.
Topics: Adult; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; Child; Cobalt Radioisotope | 1974 |
Deficient DNA repair in human progeroid cells.
Topics: Centrifugation, Density Gradient; DNA; DNA Repair; Fetus; Fibroblasts; Humans; Kinetics; Progeria; R | 1973 |
Progeria: reduced growth of human progeric-mouse hybrids.
Topics: Adult; Animals; Carcinoma, Ehrlich Tumor; Cell Fusion; Cell Line; Child; Clone Cells; Cytogenetics; | 1974 |
Erythrokeratodermia congenitalis progressiva symmetrica (Gottron). II. An analysis of kinetics of epidermal cell proliferation.
Topics: Adult; Autoradiography; Cell Differentiation; Cell Division; Female; Humans; Keratosis; Mitosis; Pro | 1971 |
Progeria: a cell culture study on aging.
Topics: Aging; Clone Cells; Culture Techniques; Cytogenetics; DNA; Female; Fibroblasts; Genes, Recessive; He | 1971 |