chloroquine has been researched along with Progeria in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Progeria: An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qian, M | 1 |
| Liu, Z | 1 |
| Peng, L | 1 |
| Tang, X | 1 |
| Meng, F | 1 |
| Ao, Y | 1 |
| Zhou, M | 1 |
| Wang, M | 1 |
| Cao, X | 1 |
| Qin, B | 1 |
| Wang, Z | 1 |
| Zhou, Z | 1 |
| Wang, G | 1 |
| Gao, Z | 1 |
| Xu, J | 1 |
| Liu, B | 1 |
1 other study available for chloroquine and Progeria
| Article | Year |
|---|---|
Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Caenorhabditis elegans; Chloroquine; DNA Repair; Lo | 2018 |