mitomycin has been researched along with Progeria in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Progeria: An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, K | 1 |
| Wada, K | 1 |
| Matsumoto, K | 1 |
| Moriya, M | 1 |
| Stefanini, M | 1 |
| Orecchia, G | 1 |
| Rabbiosi, G | 1 |
| Nuzzo, F | 1 |
2 other studies available for mitomycin and Progeria
| Article | Year |
|---|---|
Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations.
Topics: Amino Acid Sequence; Animals; Chromosome Aberrations; Cockayne Syndrome; DNA Repair; DNA-Binding Pro | 2015 |
Altered cellular response to UV irradiation in a patient affected by premature ageing.
Topics: Adult; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Fibroblasts; Humans; In Vitro Techniques | 1986 |