thalidomide has been researched along with Pleural Effusion, Malignant in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Pleural Effusion, Malignant: Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 74-year-old man with multiple myeloma was refractory to melphalan/prednisolone (MP), high-dose dexamethasone and VAD chemotherapy." | 5.35 | Refractory plasmablastic type myeloma with multiple extramedullary plasmacytomas and massive myelomatous effusion: remarkable response with a combination of thalidomide and dexamethasone. ( Kakimoto, T; Mihara, A; Nakazato, T; Sanada, Y; Suzuki, K, 2009) |
| "A 74-year-old man with multiple myeloma was refractory to melphalan/prednisolone (MP), high-dose dexamethasone and VAD chemotherapy." | 1.35 | Refractory plasmablastic type myeloma with multiple extramedullary plasmacytomas and massive myelomatous effusion: remarkable response with a combination of thalidomide and dexamethasone. ( Kakimoto, T; Mihara, A; Nakazato, T; Sanada, Y; Suzuki, K, 2009) |
| "Serous effusions in multiple myeloma are uncommon but a myelomatous pleural effusion occurring in these patients is extremely rare." | 1.33 | Myelomatous pleural effusion. ( Advani, SH; Ghosh, S; Gopal, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Comba, IY | 1 |
| Chahin, A | 1 |
| Taj, H | 1 |
| Carilli, A | 1 |
| Lázaro Sierra, J | 1 |
| Carrasco, V | 1 |
| Cases, E | 1 |
| Gómez Gonzalez, C | 1 |
| Velasco-Álvarez, D | 1 |
| Gorospe-Sarasúa, L | 1 |
| Fra-Fernández, S | 1 |
| Blanchard, MJ | 1 |
| Nakazato, T | 1 |
| Suzuki, K | 1 |
| Mihara, A | 1 |
| Sanada, Y | 1 |
| Kakimoto, T | 1 |
| Hada, M | 1 |
| Pauzner, R | 1 |
| Mayan, H | 1 |
| Waizman, A | 1 |
| Rozenman, J | 1 |
| Farfel, Z | 1 |
| Ghosh, S | 1 |
| Gopal, R | 1 |
| Advani, SH | 1 |
1 review available for thalidomide and Pleural Effusion, Malignant
| Article | Year |
|---|---|
Two cases of permanent indwelling catheter for long-term administration of intrapleural chemotherapy.
Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bortezom | 2017 |
6 other studies available for thalidomide and Pleural Effusion, Malignant
| Article | Year |
|---|---|
Pomalidomide and dexamethasone in myelomatous pleural effusion.
Topics: Dexamethasone; Drainage; Dyspnea; Humans; Male; Middle Aged; Multiple Myeloma; Plasma Cells; Pleural | 2020 |
Extramedullary Multiple Myeloma With Pleural Involvement: A Rare Clinical Entity.
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 2019 |
Refractory plasmablastic type myeloma with multiple extramedullary plasmacytomas and massive myelomatous effusion: remarkable response with a combination of thalidomide and dexamethasone.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Humans; Male; Multiple Myeloma; | 2009 |
[Report of two cases with pleural effusion and ascites that responded dramatically to the combination of thalidomide, celecoxib, irinotecan, and CDDP infused in thoracic and abdominal cavities].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Camptothecin; | 2004 |
Successful thalidomide treatment of persistent chylous pleural effusion in disseminated lymphangiomatosis [corrected].
Topics: Angiogenesis Inhibitors; Bone Neoplasms; Chylothorax; Female; Humans; Lymphangiomyoma; Middle Aged; | 2007 |
Myelomatous pleural effusion.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Doxorub | 2006 |