mitoxantrone has been researched along with Pleural Effusion, Malignant in 16 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Pleural Effusion, Malignant: Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone hydrochloride is an anthracenodione that has been reported to be useful when used intracavitary for malignant effusion due to gynaecological malignancies." | 5.29 | Mitoxantrone for malignant pleural effusion due to metastatic sarcoma. ( Holmes, EC; Kelly, J; Rosen, G, 1993) |
| "Mitoxantrone could cause an intrapleural inflammatory reaction." | 5.29 | [Therapy of pronounced pleural and pericardial effusion in metastatic breast cancer with local mitoxantrone and radiation therapy. Presentation of the intrapleural cytologic findings during this therapy]. ( Blohmer, JU; Kohls, A; Lau, HU, 1993) |
| "Thirty cases (breast cancer-20 cases, malignant lymphoma-4 cases, different malignancies-6 cases) of histologically/cytologically verified malignant pleural effusion (MPE) in 29 patients were treated with intrapleurally instilled mitoxantrone (30 mg)." | 5.08 | Intrapleurally instilled mitoxantrone in metastatic pleural effusions: a phase II study. ( Aasebø, U; Norum, J; Sager, G; Slørdal, L, 1997) |
| "Mitoxantrone has been tested recently in the treatment of effusions, and preliminary results suggest high efficacy of this drug in the treatment of peritoneal, pericardial, and pleural effusions." | 2.67 | Bleomycin and mitoxantrone in the treatment of malignant pleural effusions. A comparative study. ( Kontkanen, T; Maiche, AG; Möykkynen, K; Porkka, K; Virkkunen, P, 1993) |
| "Mitoxantrone hydrochloride is an anthracenodione that has been reported to be useful when used intracavitary for malignant effusion due to gynaecological malignancies." | 1.29 | Mitoxantrone for malignant pleural effusion due to metastatic sarcoma. ( Holmes, EC; Kelly, J; Rosen, G, 1993) |
| "Mitoxantrone could cause an intrapleural inflammatory reaction." | 1.29 | [Therapy of pronounced pleural and pericardial effusion in metastatic breast cancer with local mitoxantrone and radiation therapy. Presentation of the intrapleural cytologic findings during this therapy]. ( Blohmer, JU; Kohls, A; Lau, HU, 1993) |
| "Twelve patients received intrapleural instilments of the cytostatic agent mitoxantrone in a total dosage of 30 mg for locoregional palliative therapy of malignant pleural effusion." | 1.28 | Local therapy of malignant pleural effusion with mitoxantrone. ( Opri, F; Torsten, U; Weitzel, H, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (87.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaw, PH | 1 |
| Agarwal, R | 2 |
| Shaw, P | 1 |
| Morales, M | 1 |
| Expósito, MC | 1 |
| Maiche, AG | 1 |
| Virkkunen, P | 1 |
| Kontkanen, T | 1 |
| Möykkynen, K | 1 |
| Porkka, K | 1 |
| Ozyilkan, O | 1 |
| Kars, A | 1 |
| Güler, N | 1 |
| Tekuzman, G | 1 |
| Baltali, E | 1 |
| Firat, D | 1 |
| Kelly, J | 1 |
| Holmes, EC | 1 |
| Rosen, G | 1 |
| Blohmer, JU | 1 |
| Kohls, A | 1 |
| Lau, HU | 1 |
| Bjermer, L | 1 |
| Gruber, A | 1 |
| Sue-Chu, M | 1 |
| Sandström, T | 1 |
| Eksborg, S | 1 |
| Henriksson, R | 1 |
| Aasebø, U | 1 |
| Norum, J | 1 |
| Sager, G | 1 |
| Slørdal, L | 1 |
| Schmidt, M | 1 |
| Schaarschmidt, G | 1 |
| Chemaissani, A | 1 |
| Kahles, H | 1 |
| Bastian, HJ | 1 |
| Schiffmann, O | 1 |
| Geck, M | 1 |
| Helmke, FR | 1 |
| Golz, N | 1 |
| van Belle, AF | 1 |
| ten Velde, GP | 1 |
| Wouters, EF | 1 |
| Krismann, M | 1 |
| Pieper, K | 1 |
| Müller, KM | 1 |
| Tejler, G | 1 |
| Torsten, U | 1 |
| Opri, F | 1 |
| Weitzel, H | 1 |
| Seitzer, D | 1 |
| Musch, E | 1 |
| Kuhn, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Management Of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis[NCT03781908] | Phase 1/Phase 2 | 50 participants (Anticipated) | Interventional | 2019-01-01 | Not yet recruiting | ||
| A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions[NCT00758316] | Phase 3 | 120 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitoxantrone and Pleural Effusion, Malignant
| Article | Year |
|---|---|
WITHDRAWN: Pleurodesis for malignant pleural effusions.
Topics: Humans; Mitoxantrone; Pleural Effusion, Malignant; Pleurodesis; Propionibacterium acnes; Quinacrine; | 2013 |
Pleurodesis for malignant pleural effusions.
Topics: Humans; Mitoxantrone; Pleural Effusion, Malignant; Pleurodesis; Propionibacterium acnes; Quinacrine; | 2004 |
5 trials available for mitoxantrone and Pleural Effusion, Malignant
| Article | Year |
|---|---|
Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Instillation, Drug; Male; Middle Aged; Mitoxantrone; | 1995 |
Bleomycin and mitoxantrone in the treatment of malignant pleural effusions. A comparative study.
Topics: Aged; Bleomycin; Humans; Middle Aged; Mitoxantrone; Pleural Effusion, Malignant | 1993 |
Effects of intrapleural mitoxantrone and mepacrine on malignant pleural effusion--a randomised study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fever; Humans; Male; Middle Aged; Mit | 1995 |
Intrapleurally instilled mitoxantrone in metastatic pleural effusions: a phase II study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, A | 1997 |
[Pleurodesis in malignant pleural effusion: bleomycin vs. mitoxantrone].
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Female; Humans; Male; Middle Ag | 1997 |
9 other studies available for mitoxantrone and Pleural Effusion, Malignant
| Article | Year |
|---|---|
Intrapleural and intraperitoneal palliative treatment of malignant effusions with mitoxantrone.
Topics: Adult; Aged; Female; Humans; Injections, Intraperitoneal; Male; Middle Aged; Mitoxantrone; Palliativ | 1993 |
Mitoxantrone for malignant pleural effusion due to metastatic sarcoma.
Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged | 1993 |
[Therapy of pronounced pleural and pericardial effusion in metastatic breast cancer with local mitoxantrone and radiation therapy. Presentation of the intrapleural cytologic findings during this therapy].
Topics: Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Female; Humans | 1993 |
[Mitoxantrone-induced acute left heart failure after intrapleural administration].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Dose-R | 1997 |
Chemical pleurodesis with mitoxantrone in the management of malignant effusions.
Topics: Antineoplastic Agents; Humans; Mitoxantrone; Pleural Effusion, Malignant; Pleurodesis | 1998 |
[Pleural reaction pattern after talc pleurodesis].
Topics: Follow-Up Studies; Foreign-Body Reaction; Humans; Microscopy, Electron, Scanning; Mitoxantrone; Pleu | 1998 |
[Is intrapleural mitoxantrone treatment of pleural effusion effective in pleural metastasis from breast cancer?].
Topics: Aged; Breast Neoplasms; Drainage; Female; Humans; Mitoxantrone; Palliative Care; Pleural Effusion, M | 1992 |
Local therapy of malignant pleural effusion with mitoxantrone.
Topics: Drainage; Female; Follow-Up Studies; Humans; Mitoxantrone; Pleural Effusion, Malignant | 1992 |
[Local treatment of malignant pleural effusion in gynecologic tumors].
Topics: Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mitoxantrone; Ovaria | 1990 |