Venous Insufficiency

Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.

Synonym
Venous Insufficiency

Excerpt	Reference
"Chronic venous insufficiency is frequent and burdened with potentially serious consequences."	( Ernst, E; Saradeth, T, 1992)
"Venous insufficiency is a widespread condition, the prevalence of venous ulceration being 0."	( Browse, NL; Rutt, DL; Wilson, NM, 1991)
"Chronic venous insufficiency is characterized by decreased efficiency of the veno-muscular pump function."	( von Uslar, D, 1988)
"The incidence of venous insufficiency is increasing, approximately 800,000 new cases are reported yearly in the United States."	( Mentzer, R; Rigan, D; Shores, RM; Taheri, SA; Wels, P, 1988)
"Superficial venous insufficiency is benefited by surgical treatment, whereas deep venous insufficiency is controlled by means of elastic compression, elevation of the legs, and exercising of the leg muscles."	( Lofgren, EP, 1983)
"Venous insufficiency is necessary but not sufficient to cause ulceration, and a deficiency of the calf muscle pump is significant to the severity of venous ulceration."	( Araki, CT; Back, TL; Duran, WN; Hobson, RW; Jamil, Z; Lee, BC; Padberg, FT; Thompson, PN, 1994)
"Chronic venous insufficiency is usually quantified by venous pressure measurement, which is an invasive method."	( Baudot, N; Gaitz, JP; Gouny, P; Maurel, A; Nussaume, O; Vayssairat, M, 1994)
"Chronic edema in venous insufficiency is associated with leg ulceration, whereas in lymphedema skin ulceration is less frequent and edema from cardiac failure does not cause major skin changes."	( Gniadecka, M, 1996)
"Chronic venous insufficiency is a common primary care problem associated with significant morbidity and health care costs."	( Alguire, PC; Mathes, BM, 1997)
"Chronic venous insufficiency is a recalcitrant, recurrent medical problem."	( Alguire, PC; Mathes, BM, 1997)
"Severe chronic venous insufficiency is found in limbs with high reflux velocity (greater than 30 cm/second) and the duration of reflux does not correlate with severe chronic insufficiency."	( Nozaki, M; Sasaki, K; Yamaki, T, 2000)
"Chronic venous insufficiency is a widespread disease that can often lead to venous leg ulcers."	( Bayer, PM; Bednar, R; Fink, AM; Kottas-Heldenberg, A; Steiner, A, 2003)
"Chronic venous insufficiency is basically established by medical history and clinical findings."	( Do, DD; Husmann, M, 2007)
"Superficial venous insufficiency is a common problem associated with varicose veins."	( Akhan, O; Aktas, AR; Cetin, M; Eris, HN; Gürses, C; Kayan, M; Köroglu, M; Parlak, C; Yeşildağ, A, 2011)
"Venous insufficiency is a common medical condition affecting up to 50."	( Greenway, H; Housman, L; Moul, DK; Romine, S, 2014)
"Superficial venous insufficiency is a common cause of lower-extremity symptoms of pain and swelling."	( Khilnani, NM; Winokur, RS, 2014)
"Venous insufficiency is still a serious clinical problem."	( Karuga-Kuźniewska, E; Pohl, P; Radwan-Oczko, M; Rusak, A; Rybak, Z; Stolarski, M; Szymonowicz, M; Wiatrak, B; Wiglusz, RJ, 2018)
"Venous insufficiency is thought to be one of the most common vein diseases."	( Karuga-Kuźniewska, E; Pohl, P; Radwan-Oczko, M; Rusak, A; Rybak, Z; Stolarski, M; Szymonowicz, M; Wiatrak, B; Wiglusz, RJ, 2018)
"Chronic venous insufficiency is a highly prevalent disease in the western population."	( Slíva, J, 2019)
"Chronic venous insufficiency is an important health problem; small saphenous vein (SSV) insufficiency is one of the leading causes and may affect up to 20% of adults."	( Demirtaş, MM; Güler, E; Günay, R; Karakaya, C; Kehlibar, T; Ketenci, B; Memetoğlu, ME; Özhan, A; Yılmaz, M, 2020)
"Venous insufficiency is a common medical condition that affects many individuals, especially those with advanced age."	( Chaudhry, S; Lee, K, 2024)

Excerpt	Reference
"The anatomy of venous insufficiency has been clarified with duplex ultrasound, thus allowing appropriately directed therapy."	( Bilof, ML; Luka, NL; Petrillo, KA; Sales, CM, 1996)
"Chronic venous insufficiency has a high impact on the healthcare system due to its high incidence worldwide."	( Baldini, LO; Fanelli, C; Iannitti, T; Morales-Medina, JC; Palmieri, B; Urso, SU; Vadalà, M, 2022)

Excerpt	Reference
"Patients undergoing treatment for venous insufficiency should have all venous abnormalities investigated, defined and corrected where possible."	( Browse, NL; Rutt, DL; Wilson, NM, 1991)
"Medical treatment of venous insufficiency syndrome has been associated with a high incidence of failure."	( Mentzer, R; Rigan, D; Shores, RM; Taheri, SA; Wels, P, 1988)
"Annular constriction is effective in treating severe venous insufficiency of legs."	( Ma, J; Wang, W; Xing, Z; Zhang, J; Zhang, L, 2000)
"After being treated for venous insufficiency and malleolus ulceration, this patient woke up covered in itchy, painful plaques."	( Bucher, J; Osswald, S; Rahnama-Moghadam, S, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	617 (32.92)	23.3326
1990's	445 (23.75)	12.5806
2000's	383 (20.44)	18.1394
2010's	327 (17.45)	28.8240
2020's	102 (5.44)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	2	0
bromide	medium	1	1
carbamates	low	1	0
coumarin	medium	7	2
salicylic acid	low	2	0
lactic acid	medium	4	1
dimethyl sulfoxide	medium	2	1
glycine	low	1	0
glycerol	low	4	0
dalteparin	medium	4	1
histamine	low	1	0
hydroquinone	low	1	0
iodine	medium	4	2
thioctic acid	low	1	0
inositol	low	2	0
nickel	low	1	0
niacinamide	medium	1	1
4-aminobenzoic acid	low	4	0
thiamine	medium	5	3
uric acid	low	2	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
phenytoin	low	1	0
alprazolam	low	1	0
aspirin	medium	11	2
azathioprine	low	1	0
benzbromarone	medium	3	2
bupivacaine	low	1	0
busulfan	medium	1	1
caffeine	low	1	0
verapamil	low	1	0
cefuroxime	low	1	0
cetylpyridinium	low	1	0
chloroquine	low	1	0
cimetidine	low	1	0
ciprofloxacin	medium	1	1
diclofenac	low	1	0
dipyridamole	low	2	0
erythrosine	low	3	0
etilefrine	low	1	0
flufenamic acid	low	1	0
fluorouracil	low	1	0
furosemide	low	2	0
gabapentin	low	1	0
gentamicin	low	1	0
glutaral	low	1	0
guaifenesin	low	1	0
heptaminol	medium	7	3
hydrochlorothiazide	low	1	0
hydroxyurea	low	2	0
ibuprofen	medium	2	1
lidocaine	medium	8	1
iohexol	low	3	0
iomeprol	low	1	0
iotrolan	low	2	0
ioxaglate	low	2	0
isoxsuprine	low	1	0
ketoconazole	low	1	0
nafronyl	low	2	0
nifedipine	low	1	0
nitroglycerin	medium	4	1
ofloxacin	low	3	0
papaverine	low	18	0
pd 98059	low	1	0
pentobarbital	low	1	0
pentoxifylline	medium	12	2
phenylbutazone	medium	1	1
potassium chloride	low	1	0
potassium iodide	low	1	0
4-aminobenzoic acid	medium	5	1
procaine	low	2	0
propidium	low	1	0
propranolol	low	1	0
ropinirole	low	1	0
secobarbital	medium	1	1
vorinostat	low	1	0
theobromine	low	3	0
ticlopidine	low	1	0
triamterene	medium	8	4
prednisolone	medium	2	1
phentolamine	low	7	0
aldosterone	low	2	0
prednisone	low	2	0
oxandrolone	low	1	0
pilocarpine	low	1	0
ethinyl estradiol	low	1	0
adenosine diphosphate	low	1	0
phenylephrine	low	1	0
levodopa	low	2	0
tyrosine	low	2	0
methylene blue	low	1	0
androstenedione	low	2	0
ethylene	low	1	0
isoprene	low	1	0
methylprednisolone	low	1	0
isosorbide dinitrate	medium	1	1
benzoyl peroxide	low	1	0
ergotamine	low	2	0
framycetin	low	3	0
sulfan blue	low	1	0
diatrizoate meglumine	low	2	0
iodohippuric acid	low	3	0
yohimbine	low	1	0
catechin	medium	1	1
pyrazines	low	1	0
nitroblue tetrazolium	low	1	0
nandrolone	low	1	0
fusarium	low	1	0
dihydroergotamine	medium	17	3
hesperidin	medium	50	23
malondialdehyde	low	4	0
3-hydroxyflavone	low	1	0
c.i. 42510	low	1	0
zinc oxide	low	6	0
d-alpha tocopherol	medium	2	1
fluorescein	low	1	0
sulfur hexafluoride	low	1	0
fructosamine	low	1	0
floxacillin	low	1	0
enbucrilate	medium	18	3
mercury	low	2	0
platinum	medium	2	1
silver	medium	1	1
technetium	low	13	0
titanium	low	1	0
gadolinium	low	2	0
xenon	low	3	0
yttrium	low	1	0
ferrous sulfate	low	1	0
barium sulfate	low	1	0
zinc sulfate	low	1	0
ozone	low	1	0
trolamine salicylate	low	9	0
stanozolol	medium	2	1
calcium dobesilate	medium	25	12
triamcinolone	low	1	0
sulfolane	low	1	0
chloroprene	low	1	0
timolol	low	2	0
paclitaxel	medium	4	1
dobutamine	low	1	0
desogestrel	medium	1	1
propiconazole	low	2	0
pergolide	low	1	0
octenidine	low	1	0
fomesafen	low	3	0
cabergoline	low	1	0
itraconazole	medium	2	1
clopidogrel	low	1	0
atorvastatin	low	1	0
tirofiban	low	1	0
adenosine	low	3	0
hydrochlorothiazide-triamterene	low	1	0
chloroquine diphosphate	low	1	0
iopamidol	low	1	0
cephalosporin c	low	1	0
xenon radioisotopes	low	6	0
naftazone	medium	1	1
iotasul	low	1	0
aminaftone	medium	5	1
fibrinogen	medium	21	4
homocysteine	low	3	0
procyanidin	medium	2	1
asiaticoside	medium	1	1
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
pramipexole	low	1	0
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
risarestat	medium	1	1
docetaxel anhydrous	low	1	0
naproxen	low	1	0
chromocarb diethylamine	medium	1	1
angiotensin ii	low	1	0
tribenoside	medium	4	1
cortisone	low	1	0
3-nitrotyrosine	low	1	0
benzofurans	medium	1	1
benzarone	medium	3	2
trimethoprim, sulfamethoxazole drug combination	low	1	0
povidone-iodine	low	1	0
carboplatin	low	1	0
fibrin	low	16	0
bradykinin	low	1	0
elastin	low	4	0
taxifolin	low	1	0
inositol 3-phosphate	low	1	0
quinidine	low	1	0
digitoxin	low	1	0
betadex	low	1	0
tacrolimus	low	2	0
cocaine	low	1	0
dactinomycin	low	1	0
melphalan	medium	1	1
riboflavin	low	1	0
potassium permanganate	low	2	0
bromochloroacetic acid	low	2	0
glycosides	medium	8	2
chalcone	medium	3	2
polidocanol	medium	55	23
iothalamate meglumine	low	2	0
flunarizine	medium	1	1
curcumin	low	1	0
cinnarizine	medium	2	2
nadp	low	1	0
fusidic acid	low	1	0
thiopental	low	1	0
lithium	low	1	0
nitinol	low	3	0
hidrosmin	medium	4	1
alpha-chymotrypsin	medium	2	1
naphthoquinones	medium	1	1
quercetin	medium	9	3
vitamin k semiquinone radical	low	1	0
alprostadil	low	10	0
cholecalciferol	low	1	0
rutin	medium	77	45
6-ketoprostaglandin f1 alpha	low	2	0
esculin	low	2	0
fondaparinux	medium	3	1
phenylephrine hydrochloride	low	1	0
rutin sulfate	low	1	0
acitretin	low	1	0
oxymorphone	low	1	0
morphine	low	1	0
clobetasol	low	1	0
desoximetasone	low	1	0
iloprost	low	2	0
lysophosphatidylcholines	low	1	0
antimony	low	1	0
aluminum	low	1	0
indium	low	1	0
sulfur	medium	2	1
phosphorus	low	1	0
heroin	low	2	0
troxerutin	medium	29	19
venalot	medium	2	2
dihydroergotoxine	low	2	0
hesperidin methylchalcone	medium	4	2
glucuronyl glucosamine glycan sulfate	medium	12	3
beta-escin	medium	26	13
beta-escin	medium	15	7
gadolinium dtpa	low	2	0
ergoline	low	1	0
etonogestrel	medium	1	1
phosphocreatine	low	1	0
chlorhexidine	low	1	0
mocetinostat	low	5	0
rivaroxaban	low	4	0
s 5682	medium	19	7
apixaban	low	2	0
indocyanine green	low	2	0
phytosterols	medium	1	1
atrial natriuretic factor	medium	3	1
s6c sarafotoxin	low	1	0
cellulose	low	1	0
endothelin-1	low	2	0
phosphatidylcholines	medium	6	4
nsc 23766	low	1	0
sapogenins	low	1	0
sodium tetradecyl sulfate	medium	15	5
sodium pertechnetate tc 99m	low	2	0
gadofosveset trisodium	low	1	0
cardiovascular agents	medium	40	10
interleukin-8	low	1	0
natriuretic peptide, brain	medium	4	1
heme	low	2	0
heparitin sulfate	medium	1	1
ascorbic acid	medium	10	3
acenocoumarol	low	2	0
warfarin	medium	29	5
phenprocoumon	low	1	0
transforming growth factor beta	low	6	0
acp-196	low	1	0
nattokinase	medium	1	1
teca	medium	10	9
hyaluronoglucosaminidase	low	1	0
dihydroergotoxine mesylate, esculoside, rutoside drug combination	low	1	0
flavin mononucleotide	medium	1	1
lactoferrin	low	1	0
orabase	low	1	0
technetium tc 99m medronate	low	3	0
thromboplastin	low	1	0
muramidase	low	1	0
inosine diphosphate	medium	1	1
allopurinol	low	1	0
phosphocreatinine	low	1	0
defibrotide	medium	2	1
eye	low	4	0

Protein Targets (1,752)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	19	0	0	19
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	5	0	0	5
thioredoxin reductase	44	0	0	44
USP1 protein, partial	38	0	0	38
TDP1 protein	77	0	0	77
vitamin D3 receptor isoform VDRA	24	0	0	24
importin subunit beta-1 isoform 1	15	0	0	15
flap endonuclease 1	25	0	0	25
serine/threonine-protein kinase PLK1	7	0	0	7
snurportin-1	15	0	0	15
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	17	0	0	17
GTP-binding nuclear protein Ran isoform 1	8	0	0	8
DNA polymerase eta isoform 1	11	0	0	11
DNA polymerase iota isoform a (long)	31	0	0	31
urokinase-type plasminogen activator precursor	17	0	0	17
plasminogen precursor	17	0	0	17
urokinase plasminogen activator surface receptor precursor	17	0	0	17
geminin	76	0	0	76
DNA polymerase kappa isoform 1	24	0	0	24
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	3	0	3
Transthyretin	0	1	3	6
Fatty acid-binding protein, intestinal	0	4	1	5
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	2	1	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	11	0	0	11
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	4	0	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	44	0	0	44
Chain A, Cruzipain	13	0	0	13
regulator of G-protein signaling 4	27	0	0	27
Platelet-activating factor receptor	0	2	0	3
Inositol monophosphatase 1	15	0	0	15
Chain A, 2-oxoglutarate Oxygenase	25	0	0	25
glp-1 receptor, partial	19	0	0	19
Smad3	18	0	0	18
apical membrane antigen 1, AMA1	7	0	0	7
cellular tumor antigen p53 isoform a	12	0	0	12
mitogen-activated protein kinase 1	21	0	0	21
nuclear receptor ROR-gamma isoform 1	32	0	0	32
cytochrome P450 3A4 isoform 1	34	0	0	34
lamin isoform A-delta10	60	0	0	60
Gamma-aminobutyric acid receptor subunit pi	34	8	2	44
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	2	0	12
Carbonic anhydrase 12	0	9	0	15
Carbonic anhydrase 1	0	20	0	27
Carbonic anhydrase 2	0	22	0	31
Integrin beta-3	10	3	1	15
ATP-dependent translocase ABCB1	0	19	3	33
Integrin alpha-IIb	10	2	1	14
Calmodulin-1	0	3	0	3
Androgen receptor	0	6	1	7
Pyruvate kinase PKM	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	34	8	2	44
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	3
Polyunsaturated fatty acid lipoxygenase ALOX12	0	2	0	3
Gamma-aminobutyric acid receptor subunit delta	34	8	2	44
Gamma-aminobutyric acid receptor subunit gamma-2	34	8	3	45
Gamma-aminobutyric acid receptor subunit alpha-5	34	8	2	44
Gamma-aminobutyric acid receptor subunit alpha-3	34	8	2	44
Gamma-aminobutyric acid receptor subunit gamma-1	34	8	2	44
Gamma-aminobutyric acid receptor subunit alpha-2	34	8	2	44
Gamma-aminobutyric acid receptor subunit alpha-4	34	8	2	44
Gamma-aminobutyric acid receptor subunit gamma-3	34	8	2	44
Gamma-aminobutyric acid receptor subunit alpha-6	34	8	2	44
Histamine H2 receptor	22	3	2	27
Xanthine dehydrogenase/oxidase	0	7	0	7
Fatty acid synthase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	34	9	3	46
Gamma-aminobutyric acid receptor subunit beta-3	34	8	2	44
Gamma-aminobutyric acid receptor subunit beta-2	34	8	3	45
Cytochrome P450 1B1	0	5	1	6
Carbonic anhydrase 9	0	12	0	19
GABA theta subunit	34	8	2	44
Aurora kinase B	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	34	8	2	44
Dipeptidyl peptidase 3	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	15	0	0	15
phosphopantetheinyl transferase	27	0	0	27
bromodomain adjacent to zinc finger domain 2B	17	0	0	17
euchromatic histone-lysine N-methyltransferase 2	71	0	0	71
pyruvate kinase PKM isoform a	3	0	0	3
Glycoprotein hormones alpha chain	3	0	0	3
Tubulin--tyrosine ligase	0	2	0	2
Genome polyprotein	0	1	1	2
AR protein	95	0	0	95
thyroid stimulating hormone receptor	31	0	0	31
glucocorticoid receptor [Homo sapiens]	75	0	0	75
retinoic acid nuclear receptor alpha variant 1	58	0	0	58
estrogen nuclear receptor alpha	104	0	0	104
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	44	0	0	44
Histone H2A.x	32	0	0	32
chromobox protein homolog 1	44	0	0	44
transcriptional regulator ERG isoform 3	7	0	0	7
Polyphenol oxidase 2	0	9	0	14
Cellular tumor antigen p53	63	0	0	63
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Dihydropteroate synthase	0	0	1	1
Chain A, Toluene-4-monooxygenase system protein A	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Luciferase	34	0	0	34
RAR-related orphan receptor gamma	59	0	0	59
retinoid X nuclear receptor alpha	57	0	0	57
G	27	0	0	27
peroxisome proliferator activated receptor gamma	55	0	0	55
thyroid stimulating hormone receptor	29	0	0	29
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	12	0	0	12
muscleblind-like protein 1 isoform 1	18	0	0	18
Interferon beta	38	0	0	38
HLA class I histocompatibility antigen, B alpha chain	27	0	0	27
Inositol hexakisphosphate kinase 1	27	0	0	27
cytochrome P450 2C9, partial	27	0	0	27
Microtubule-associated protein tau	32	0	0	32
aldehyde dehydrogenase 1 family, member A1	46	0	0	46
thyroid hormone receptor beta isoform 2	65	0	0	65
eyes absent homolog 2 isoform a	4	0	0	4
peripheral myelin protein 22	31	0	0	31
survival motor neuron protein isoform d	29	0	0	29
histone acetyltransferase KAT2A isoform 1	22	0	0	22
ATP-binding cassette sub-family C member 3	0	48	0	48
Multidrug resistance-associated protein 4	0	48	0	49
Bile salt export pump	0	13	0	13
Bile salt export pump	0	72	0	72
Rap guanine nucleotide exchange factor 3	11	0	0	11
Rap guanine nucleotide exchange factor 4	5	0	0	5
Epidermal growth factor receptor	0	10	2	12
Receptor tyrosine-protein kinase erbB-2	0	3	1	4
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase Blk	0	1	1	2
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
Tyrosine-protein kinase JAK3	0	1	1	2
Synaptic vesicular amine transporter	0	1	0	1
Tyrosine-protein kinase BTK	0	1	2	3
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Platelet glycoprotein VI	0	1	1	2
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
NPYLR7B	0	0	3	3
arylsulfatase A	27	0	0	27
IDH1	24	0	0	24
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	35	0	0	35
Purine nucleoside phosphorylase	0	1	0	1
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	3	2	6
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	15	3	19
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	1	0	2
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	3
Glutamate receptor 2	36	0	0	36
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	9	1	14
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	7	5	14
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	4	1	6
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	5	3	11
Adenosine receptor A2a	0	10	2	17
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	10	4	17
Delta-type opioid receptor	0	10	3	16
Kappa-type opioid receptor	0	6	3	12
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
thyroid hormone receptor beta isoform a	29	0	0	29
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	18
Sex hormone-binding globulin	0	0	7	7
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	3	3	6
Androgen receptor	0	13	0	13
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
interleukin 8	16	0	0	16
estrogen receptor 2 (ER beta)	40	0	0	40
progesterone receptor	45	0	0	45
estrogen-related nuclear receptor alpha	71	0	0	71
Bloom syndrome protein isoform 1	25	0	0	25
ras-related protein Rab-9A	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	67	0	0	67
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	5	1	8
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	21	0	0	21
Canalicular multispecific organic anion transporter 1	0	47	0	47
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	3
pregnane X nuclear receptor	62	0	0	62
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	20	0	0	20
Bromodomain-containing protein 4	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	2	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	2	7
Cholecystokinin receptor type A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	3	8
Gamma-aminobutyric acid receptor subunit beta-2	0	5	2	7
Cholecystokinin receptor type A	0	1	0	1
ATPase family AAA domain-containing protein 5	32	0	0	32
Ataxin-2	39	0	0	39
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	3	2	5
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	15	0	0	15
Chain A, Ferritin light chain	18	0	0	18
Chain A, Apolipoprotein	0	0	1	1
15-lipoxygenase, partial	15	0	0	15
ATAD5 protein, partial	27	0	0	27
cytochrome P450 family 3 subfamily A polypeptide 4	43	0	0	43
EWS/FLI fusion protein	29	0	0	30
nonstructural protein 1	18	0	0	18
D(1A) dopamine receptor	13	0	0	13
Plasminogen	0	2	1	3
Proton-coupled amino acid transporter 1	0	3	0	3
Chain A, HADH2 protein	24	0	0	24
Chain B, HADH2 protein	24	0	0	24
acetylcholinesterase	33	0	0	33
SMAD family member 2	26	0	0	26
SMAD family member 3	26	0	0	26
GLI family zinc finger 3	62	0	0	62
farnesoid X nuclear receptor	41	0	0	41
peroxisome proliferator-activated receptor delta	40	0	0	40
vitamin D (1,25- dihydroxyvitamin D3) receptor	44	0	0	44
Caspase-7	10	0	0	10
peripheral myelin protein 22 isoform 1	18	0	0	18
potassium voltage-gated channel subfamily H member 2 isoform d	27	0	0	27
caspase-3	10	0	0	10
nuclear factor NF-kappa-B p105 subunit isoform 1	6	0	0	6
neuropeptide S receptor isoform A	9	0	0	9
Beta-glucuronidase	0	1	0	1
Cholinesterase	0	11	0	11
Aromatase	0	6	0	8
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Alpha-synuclein	9	4	1	14
Nuclear receptor ROR-gamma	17	0	0	17
glucocerebrosidase	11	0	0	11
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
Coagulation factor X	0	1	0	1
Prothrombin	0	4	2	6
Coagulation factor X	0	5	0	5
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Trypsin-3	0	2	0	2
Spike glycoprotein	39	1	2	42
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	17	0	0	17
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
lethal factor (plasmid)	13	0	0	13
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	3	0	4
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	5	0	5
Alpha-2B adrenergic receptor	0	23	3	28
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	23	0	0	23
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
GLS protein	31	0	0	31
hypothetical protein, conserved	6	0	0	6
cytochrome P450 2D6	32	0	0	32
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	22	0	0	22
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	9	0	9
Prostaglandin G/H synthase 1	0	6	0	6
Prostaglandin G/H synthase 2	0	3	0	3
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	8	1	9
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	9
Substance-P receptor	0	5	0	7
Prostaglandin G/H synthase 2	0	14	0	14
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	6	0	6
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	5	0	5
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	17	1	18
Sigma non-opioid intracellular receptor 1	0	0	1	1
caspase 7, apoptosis-related cysteine protease	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	45	0	0	45
caspase-3	16	0	0	16
Solute carrier organic anion transporter family member 2B1	0	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Insulin receptor	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Histone deacetylase 1	0	9	2	14
Histone deacetylase 2	0	9	2	14
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Histone deacetylase 6	0	7	2	12
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	2	13
Solute carrier organic anion transporter family member 1B1	0	6	0	7
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Fumarate hydratase	18	0	0	18
polyprotein	18	0	0	18
P53	1	0	0	1
aryl hydrocarbon receptor	31	0	0	31
activating transcription factor 6	30	0	0	30
v-jun sarcoma virus 17 oncogene homolog (avian)	37	0	0	37
hemoglobin subunit beta	4	0	0	4
heat shock protein beta-1	27	0	0	27
M-phase phosphoprotein 8	10	0	0	10
Protein-arginine deiminase type-4	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	6
Eyes absent homolog 3	0	2	0	2
Solute carrier family 22 member 12	0	2	0	2
Eyes absent homolog 3	0	2	0	2
Chain A, Beta-lactamase	22	0	0	22
calpain II, partial	0	1	0	1
Skn7p	0	0	0	2
hypoxia-inducible factor 1 alpha subunit	29	0	0	29
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	22	0	0	22
envelope glycoprotein	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	26	0	0	26
cytochrome P450 2C19 precursor	14	0	0	14
cytochrome P450 2C9 precursor	17	0	0	17
perilipin-5	0	5	0	5
nuclear receptor corepressor 2 isoform 2	0	1	0	1
perilipin-1	0	5	0	5
DNA polymerase beta	11	0	0	11
ubiquitin carboxyl-terminal hydrolase 2 isoform a	11	0	0	11
peroxisome proliferator-activated receptor gamma isoform 2	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	5	0	5
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
streptokinase A precursor	0	0	4	4
Eyes absent homolog 2	0	1	0	1
Polymerase acidic protein	0	0	2	2
Estrogen receptor	0	0	2	2
60 kDa chaperonin	0	6	0	6
60 kDa heat shock protein, mitochondrial	0	6	0	6
Cytochrome P450 2C9	0	26	0	27
Alpha-1B adrenergic receptor	0	20	6	26
Mitogen-activated protein kinase 1	0	2	0	2
Cytochrome P450 2C19	0	10	0	10
Multidrug resistance-associated protein 1	0	5	1	7
5-hydroxytryptamine receptor 2B	0	21	2	23
Alpha-1A adrenergic receptor	0	19	6	25
Cytochrome P450 2J2	0	16	0	16
Monocarboxylate transporter 1	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	6	0	6
Disintegrin and metalloproteinase domain-containing protein 17	8	0	0	8
Aldo-keto reductase family 1 member C1	0	3	0	3
Thiosulfate sulfurtransferase	0	6	0	6
Solute carrier family 22 member 6	0	6	0	7
60 kDa chaperonin	0	6	0	6
Estrogen receptor beta	0	0	2	2
Monocarboxylate transporter 2	0	2	0	2
10 kDa chaperonin	0	6	0	6
Bile acid receptor	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
M17 leucyl aminopeptidase	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Dihydroorotate dehydrogenase	0	4	0	4
Protease	0	1	0	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	3	3
Carbonic anhydrase 4	0	14	0	20
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase 15	0	7	0	10
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	5	6
Potassium channel subfamily K member 9	0	1	0	1
Matrix metalloproteinase-9	0	5	0	5
nuclear receptor subfamily 1, group I, member 2	11	0	0	11
Histamine H3 receptor	0	2	2	4
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	6	3	9
Replicase polyprotein 1ab	0	8	3	11
Amine oxidase [flavin-containing] A	0	7	0	7
Acetylcholinesterase	0	13	0	13
Amine oxidase [flavin-containing] B	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	3	0	3
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	3	1	4
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	3	1	4
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	2	0	2
Guanine deaminase	0	2	0	2
ATP-dependent phosphofructokinase	28	0	0	28
histone-lysine N-methyltransferase 2A isoform 2 precursor	9	0	0	9
cytochrome P450 2D6 isoform 1	13	0	0	13
5-hydroxytryptamine receptor 1D	0	2	0	4
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	2	0	2
Solute carrier family 15 member 2	0	2	0	2
Carbonic anhydrase 4	0	1	0	3
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	3	0	3
Aldo-keto reductase family 1 member B1	0	13	0	13
Carbonic anhydrase 6	0	9	0	14
Sucrase-isomaltase, intestinal	0	1	0	1
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	2	0	2
Beta-secretase 1	0	6	0	6
Carbonic anhydrase 3	0	2	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	2	0	4
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	5	0	7
Solute carrier family 15 member 1	0	4	0	4
Beta-lactamase TEM	0	0	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	2
67.9K protein	15	0	0	15
interferon gamma precursor	0	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	13	0	0	13
thyrotropin-releasing hormone receptor	9	0	0	9
Caspase-2	0	0	1	1
pyruvate kinase	4	0	0	4
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	6	0	0	6
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Pancreatic alpha-amylase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Tubulin beta-4A chain	0	2	1	4
Tubulin beta chain	0	2	1	4
Tubulin alpha-3C chain	0	2	1	4
Tumor necrosis factor receptor superfamily member 1A	0	1	0	1
Endothelin receptor type B	1	0	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Endothelin-1 receptor	1	0	0	1
Quinone oxidoreductase	0	0	0	2
Stromal cell-derived factor 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Tubulin alpha-1B chain	0	2	1	4
Tubulin alpha-4A chain	0	2	1	4
Tubulin beta-4B chain	0	2	1	4
Prostaglandin G/H synthase 2	0	3	0	3
Tubulin beta-3 chain	0	3	1	5
Tubulin beta-2A chain	0	2	1	4
Tubulin beta-8 chain	0	2	1	4
Tubulin alpha-3E chain	0	2	1	4
Tubulin alpha-1A chain	0	2	1	4
Sortase A	0	2	0	2
Tubulin alpha-1C chain	0	2	1	4
Tubulin beta-6 chain	0	2	1	4
Tubulin beta-2B chain	0	2	1	4
Tubulin beta-1 chain	0	2	1	4
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
PAX8	0	0	0	2
pregnane X receptor	11	0	0	11
PINK1	3	0	0	3
Parkin	8	0	0	8
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
huntingtin isoform 2	9	0	0	9
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	3
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	2
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	6	0	8
Solute carrier family 22 member 1	0	15	0	18
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	2	0	3
Glutathione reductase, mitochondrial	0	7	0	9
72 kDa type IV collagenase	0	4	0	4
Trypanothione reductase	0	1	0	1
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	5	0	5
Multidrug and toxin extrusion protein 1	0	11	0	11
Spermine oxidase	0	1	0	1
PPM1D protein	10	0	0	10
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	1	9	0	11
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	1	2	3
Muscarinic acetylcholine receptor M2	0	6	2	9
Muscarinic acetylcholine receptor M4	0	5	0	6
Cytochrome P450 3A4	0	21	1	24
Muscarinic acetylcholine receptor M5	0	6	0	7
Alpha-2A adrenergic receptor	0	25	6	33
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Spike glycoprotein	0	2	0	2
Muscarinic acetylcholine receptor M1	0	8	3	12
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	21	4	27
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	7	1	9
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	24	0	25
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
endonuclease IV	9	0	0	9
GALC protein	8	0	0	8
Nrf2	6	0	0	6
LAP4	0	0	2	2
RPL19A	0	0	1	1
Vpr	6	0	0	6
Botulinum neurotoxin type A	0	4	0	4
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
alpha-galactosidase	2	0	0	2
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	4	0	4
ATP-dependent translocase ABCB1	0	10	0	10
Cytochrome P450 2D6	0	17	0	17
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	11	1	13
Histamine H2 receptor	0	8	4	12
Histamine H1 receptor	0	1	4	5
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	2	0	2
Solute carrier family 22 member 1	0	6	0	9
Solute carrier family 22 member 8	0	6	0	7
Histamine H4 receptor	0	3	3	6
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 2	0	6	0	8
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	4	0	0	4
Estrogen receptor 1	0	2	0	2
lysosomal alpha-glucosidase preproprotein	9	0	0	9
estrogen receptor beta isoform 1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	5	0	0	5
Neuronal acetylcholine receptor subunit beta-2	5	0	0	5
D(2) dopamine receptor	0	16	5	21
5-hydroxytryptamine receptor 1A	0	22	2	25
Sodium-dependent noradrenaline transporter	0	12	2	14
Alpha-1D adrenergic receptor	0	16	3	20
Cruzipain	0	2	0	2
5-hydroxytryptamine receptor 2A	0	16	4	20
5-hydroxytryptamine receptor 1B	0	19	0	19
Sodium-dependent serotonin transporter	0	18	0	18
Histamine H1 receptor	0	7	3	10
D(3) dopamine receptor	0	16	3	20
Sodium-dependent dopamine transporter	0	12	0	12
Cytochrome P450 1A2	0	4	0	4
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	5
DNA gyrase subunit B	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	3	0	3
MEP2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	3	0	5
Histone deacetylase 3	0	7	1	11
Carbonic anhydrase 3	0	7	0	11
Catechol O-methyltransferase	0	2	0	2
Alpha-1D adrenergic receptor	0	9	6	16
Carbonic anhydrase 5A, mitochondrial	0	10	0	15
Carbonic anhydrase 7	0	8	0	13
Histone deacetylase 4	0	6	1	10
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	6	2	11
Polyamine deacetylase HDAC10	0	5	1	9
Histone deacetylase 11	0	6	1	10
Histone deacetylase 8	0	7	3	13
Carbonic anhydrase 13	0	6	0	10
Histone deacetylase 9	0	5	1	9
Carbonic anhydrase 14	0	7	0	12
Histone deacetylase 5	0	6	1	10
heat shock protein 90, putative	0	0	0	2
Cytochrome P450 2C8	0	7	0	7
Cytochrome P450 2B6	0	4	0	4
Liver carboxylesterase 1	0	0	0	3
P2Y purinoceptor 12	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Muscarinic acetylcholine receptor M1	0	4	0	5
5-hydroxytryptamine receptor 2C	0	3	0	3
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
D	0	4	0	4
Alpha-2B adrenergic receptor	0	8	5	13
Alpha-2C adrenergic receptor	0	8	5	13
Alpha-2A adrenergic receptor	0	8	5	13
Sodium-dependent dopamine transporter	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	5	1	6
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
Sodium-dependent serotonin transporter	0	4	0	5
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	3	1	7
5-hydroxytryptamine receptor 3A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
D(2) dopamine receptor	0	8	2	10
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	3	1	7
Glutamate receptor ionotropic, NMDA 2B	0	4	1	8
Glutamate receptor ionotropic, NMDA 2C	0	3	1	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	1	7
5-hydroxytryptamine receptor 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	3	1	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
5-hydroxytryptamine receptor 3B	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	1	7
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Transporter	0	2	0	2
dopamine D1 receptor	7	0	0	7
Glucocorticoid receptor	0	14	2	21
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Exportin-1	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	2	0	4
Cytochrome P450 2A6	0	1	1	3
Aldo-keto reductase family 1 member B1	0	6	0	6
UDP-glucuronosyltransferase 2B7	0	4	0	7
UDP-glucuronosyltransferase 1-6	0	5	0	5
Amine oxidase [flavin-containing] B	0	2	0	2
Cytochrome P450 2A5	0	0	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	7	0	8
UDP-glucuronosyltransferase 1A4	0	4	0	5
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	4	0	4
Sorbitol dehydrogenase	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Zn finger protein	0	1	0	1
Carbonic anhydrase 13	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	7	0	11
Chain A, Breast cancer type 1 susceptibility protein	3	0	0	3
alkaline phosphatase, intestinal	0	1	0	1
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
tumor susceptibility gene 101 protein	2	0	0	2
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
caspase-1 isoform alpha precursor	6	0	0	6
hypothetical protein SA1422	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	6	0	6
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Microtubule-associated protein tau	0	2	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	2	0	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Heme oxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Proteasome subunit beta type-5	0	3	0	3
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Caspase-7	6	0	0	6
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	3	1	4
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
CREB-binding protein	1	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	2	0	2
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Hsf1 protein	0	0	5	5
Aldo-keto reductase family 1 member B10	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Cytochrome c oxidase subunit 2	0	2	0	2
Albumin	0	7	8	15
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
C-X-C chemokine receptor type 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Prostaglandin G/H synthase 2	0	5	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	3
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Prostaglandin G/H synthase 1	0	5	0	7
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
STAT3, partial	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
5-hydroxytryptamine receptor 4	0	16	0	16
D(1A) dopamine receptor	0	10	3	13
5-hydroxytryptamine receptor 2C	0	16	2	18
Alpha-1A adrenergic receptor	0	6	5	12
Alpha-1B adrenergic receptor	0	4	4	9
5-hydroxytryptamine receptor 6	0	11	1	12
serine-protein kinase ATM isoform a	3	0	0	3
mu-type opioid receptor isoform MOR-1	0	0	4	4
fatty acid synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	0	4	4
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	0	2
RGS12	1	0	0	1
NFKB1 protein, partial	12	0	0	12
Thrombopoietin	6	0	0	6
DNA polymerase III, partial	3	0	0	3
isocitrate dehydrogenase 1, partial	3	0	0	3
LANA	0	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	3	0	3
3',5'-cyclic-AMP phosphodiesterase	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
Exopolyphosphatase PRUNE1	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	3
Tyrosine-protein kinase Lck	0	4	0	4
Tyrosine-protein kinase Fyn	0	4	0	4
Beta-2 adrenergic receptor	0	9	2	11
Beta-1 adrenergic receptor	0	8	2	10
POU domain, class 2, transcription factor 1	0	0	0	2
Serum paraoxonase/arylesterase 1	0	3	0	3
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
Endothelin-1 receptor	0	2	1	3
Adenylate cyclase	0	1	0	1
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 5A	0	2	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Lanosterol 14-alpha demethylase	0	3	1	4
50S ribosomal protein L36 2	0	2	1	3
Genome polyprotein	0	2	1	3
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	4	0	4
Macrophage migration inhibitory factor	0	4	0	4
Taste receptor type 2 member 16	0	0	0	1
Cytochrome P450 2B1	0	1	0	1
Estrogen receptor	0	6	1	7
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Estrogen receptor beta	0	3	1	4
galanin receptor type 3	0	1	0	1
D(3) dopamine receptor isoform e	1	0	0	1
Chain A, PROTEIN (TRANSTHYRETIN)	0	0	1	1
Chain B, PROTEIN (TRANSTHYRETIN)	0	0	1	1
histone deacetylase 9 isoform 3	8	0	0	8
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Aldo-keto reductase family 1 member C4	0	2	0	2
Aldo-keto reductase family 1 member C3	0	4	0	4
Transcription factor SOX-18	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Transcriptional enhancer factor TEF-3	0	1	1	2
Potassium channel subfamily K member 18	0	1	1	2
Acid-sensing ion channel 5	0	0	1	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	2	0	2
Angiotensin-converting enzyme	0	4	0	4
Cannabinoid receptor 1	0	2	0	2
Delta-type opioid receptor	0	5	0	6
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Potassium channel subfamily K member 2	0	2	0	2
Voltage-dependent T-type calcium channel subunit alpha-1I	0	0	1	1
Prostaglandin D2 receptor 2	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Solute carrier family 22 member 8	0	1	0	2
Thymidylate synthase	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
G-protein coupled receptor 35	0	2	2	4
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	9
Neuraminidase	0	5	0	5
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Nischarin	0	1	0	1
Substance-K receptor	0	3	0	3
Heparanase	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase	0	0	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta-type opioid receptor	0	4	2	7
Mu-type opioid receptor	0	5	2	10
Mu-type opioid receptor	0	5	0	5
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Tyrosinase	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Carbonic anhydrase	0	2	0	2
Stromelysin-1	0	2	2	4
Urease subunit alpha	0	4	0	4
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	4	0	4
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Albumin	0	0	2	2
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	7
Caspase-1	0	3	0	3
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	0	1	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	0	1	1
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase	0	0	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Estrogen receptor beta	0	2	0	3
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	1	2
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	2	0	3
Substance-K receptor	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
phosphoglycerate kinase	4	0	0	4
Potassium voltage-gated channel subfamily A member 5	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	3	0	4
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	3	0	3
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
POsterior Segregation	0	0	2	2
Glutathione reductase	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	2	2
Nuclear receptor corepressor 1	0	3	0	3
Integrin beta-1	0	2	0	2
Leukotriene A-4 hydrolase	0	2	0	2
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	3	0	3
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	4
Muscarinic acetylcholine receptor M4	0	3	0	4
Muscarinic acetylcholine receptor M5	0	3	0	4
Muscarinic acetylcholine receptor M2	0	3	0	4
Histidine decarboxylase	0	0	2	2
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	3	2	6
Mu-type opioid receptor	0	3	1	6
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	2	6
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
tumor necrosis factor	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
Phospholipase A2, membrane associated	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Myosin light chain kinase, smooth muscle	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
STE24	0	0	0	1
Trypsin	0	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
caspase recruitment domain family, member 15	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	2	0	3
Catechol O-methyltransferase	0	2	0	2
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Tyrosine-protein kinase ABL1	0	2	0	2
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Integrin alpha-V	0	2	0	2
Apoptosis regulator Bcl-2	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	2
Cholecystokinin receptor type A	0	3	1	4
Melanocortin receptor 5	0	2	0	2
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	0	1
Beta-tubulin	0	1	0	1
Tubulin beta-2B chain	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	3	0	3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
pyruvate kinase PKM isoform b	2	0	0	2
RAF proto-oncogene serine/threonine-protein kinase	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
Ornithine decarboxylase	2	0	0	2
Mitogen-activated protein kinase 3	0	0	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	2	0	2
Beta-lactamase OXA-7	0	0	0	1
vasopressin V1b receptor	1	0	0	1
Tumor necrosis factor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	4	1	5
D(3) dopamine receptor	0	5	1	6
D(2) dopamine receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
D	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	3	0	3
ClpP	2	0	0	2
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	3	1	4
Alpha-1B adrenergic receptor	0	2	0	2
Nischarin	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	5	2	7
Beta-1 adrenergic receptor	0	4	1	6
Alpha-2B adrenergic receptor	0	1	0	2
Alpha-2C adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
D(4) dopamine receptor	0	2	2	4
D(1B) dopamine receptor	0	1	1	2
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Acetylcholinesterase	0	1	0	1
Beta-1 adrenergic receptor	0	1	2	4
Beta-2 adrenergic receptor	0	2	0	3
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
hexokinase	0	2	0	2
galactokinase	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Cytochrome P450 1A1	0	2	1	3
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
Hepatocyte growth factor receptor	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	2	0	2
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	2	0	2
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
G1/S-specific cyclin-D1	0	2	0	2
Dipeptidyl peptidase 4	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	2	0	2
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Receptor-type tyrosine-protein kinase FLT3	0	3	0	3
Macrophage metalloelastase	0	2	0	2
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Glycogen synthase kinase-3 alpha	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Mitogen-activated protein kinase 10	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Coagulation factor XII	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Neuraminidase	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
nonstructural protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Integrin subunit alpha 2b	0	1	0	1
Integrin alpha-5	0	1	0	1
Integrin beta-3	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, PAPAIN	1	0	0	1
putative alpha-glucosidase	1	0	0	1
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
Cathepsin G	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Pteridine reductase 1	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Glycoprotein	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Histone deacetylase 8	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
steroidogenic factor 1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Histone deacetylase 1	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Protein Tat	0	0	1	1
Leukotriene A-4 hydrolase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	1	3
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
DNA topoisomerase 1	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,874)

Protein Targets (1,752)

Venous Insufficiency

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,874)

Drugs Studied (327)

Protein Targets (1,752)