pentoxifylline has been researched along with Venous Insufficiency in 12 studies
Venous Insufficiency: Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind, placebo-controlled study was carried out in 12 patients suffering from chronic venous insufficiency and persistent leg ulcers to assess the efficacy of pentoxifylline treatment as an adjunct to compression bandaging in the conservative management of venous leg ulcers." | 9.07 | Pentoxifylline in the treatment of venous leg ulcers. ( Barbarino, C, 1992) |
| " If confirmed, it wound offer another effective and safe therapeutic option for treatment of VLUs." | 7.30 | Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study). ( Chen, L; Dai, Y; Gao, Y; Han, C; Li, B; Li, J; Li, P; Li, Q; Li, Y; Liu, M; Ran, X; Xu, J; Zhao, Y, 2023) |
| "A double-blind, placebo-controlled study was carried out in 12 patients suffering from chronic venous insufficiency and persistent leg ulcers to assess the efficacy of pentoxifylline treatment as an adjunct to compression bandaging in the conservative management of venous leg ulcers." | 5.07 | Pentoxifylline in the treatment of venous leg ulcers. ( Barbarino, C, 1992) |
| " If confirmed, it wound offer another effective and safe therapeutic option for treatment of VLUs." | 3.30 | Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study). ( Chen, L; Dai, Y; Gao, Y; Han, C; Li, B; Li, J; Li, P; Li, Q; Li, Y; Liu, M; Ran, X; Xu, J; Zhao, Y, 2023) |
| "Chronic venous insufficiency is frequent and burdened with potentially serious consequences." | 2.38 | [Conservative therapy of chronic venous insufficiency]. ( Ernst, E; Saradeth, T, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Gao, Y | 1 |
| Liu, M | 1 |
| Li, Q | 1 |
| Han, C | 1 |
| Zhao, Y | 1 |
| Li, B | 1 |
| Xu, J | 1 |
| Dai, Y | 1 |
| Li, P | 1 |
| Li, J | 1 |
| Li, Y | 1 |
| Ran, X | 1 |
| Raju, S | 1 |
| Neglén, P | 1 |
| Gohel, MS | 1 |
| Davies, AH | 1 |
| Word, R | 1 |
| Coleridge Smith, PD | 1 |
| Marston, W | 1 |
| Goodfield, M | 1 |
| Müller, R | 1 |
| Ernst, E | 1 |
| Saradeth, T | 1 |
| Barbarino, C | 1 |
| Angelides, NS | 1 |
| Weil von der Ahe, CA | 1 |
| Brenner, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Single-arm, Multi-center, Pilot Study of IVUS Imaging Used as an Adjunct to Multiplanar Venography During Iliac-common Femoral Vein Assessment for Possible Endovascular Intervention[NCT02142062] | 100 participants (Actual) | Observational | 2014-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for pentoxifylline and Venous Insufficiency
| Article | Year |
|---|---|
Clinical practice. Chronic venous insufficiency and varicose veins.
Topics: Combined Modality Therapy; Female; Humans; Laser Therapy; Middle Aged; Pentoxifylline; Platelet Aggr | 2009 |
Pharmacological treatment in patients with C4, C5 and C6 venous disease.
Topics: Calcium Dobesilate; Cardiology; Chronic Disease; Compression Bandages; Drug Therapy; Flavonoids; Hum | 2010 |
Medical and surgical therapy for advanced chronic venous insufficiency.
Topics: Bandages; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Leg | 2010 |
Deleterious effects of white cells in the course of skin damage in CVI.
Topics: Alprostadil; Cell Adhesion Molecules; Chronic Disease; Humans; Iloprost; Leg Ulcer; Leukocytes; Neut | 2002 |
Evaluation and treatment of leg ulcers associated with chronic venous insufficiency.
Topics: Chronic Disease; Humans; Laser Therapy; Leg Ulcer; Pentoxifylline; Stockings, Compression; Vasodilat | 2007 |
Optimal management of chronic leg ulcers in the elderly.
Topics: Administration, Oral; Aged; Aging; Arterial Occlusive Diseases; Aspirin; Bandages; Combined Modality | 1997 |
Pentoxifylline -- a biomedical profile.
Topics: Arterial Occlusive Diseases; Blood Viscosity; Brain Ischemia; Cerebrovascular Circulation; Erythrocy | 1979 |
[Conservative therapy of chronic venous insufficiency].
Topics: Bandages; Chronic Disease; Combined Modality Therapy; Fibrinolytic Agents; Humans; Life Style; Pento | 1992 |
2 trials available for pentoxifylline and Venous Insufficiency
| Article | Year |
|---|---|
Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study).
Topics: Humans; Leg Ulcer; Multicenter Studies as Topic; Pentoxifylline; Quality of Life; Randomized Control | 2023 |
Pentoxifylline in the treatment of venous leg ulcers.
Topics: Aged; Bandages; Chemotherapy, Adjuvant; Chronic Disease; Double-Blind Method; Female; Humans; Leg Ul | 1992 |
2 other studies available for pentoxifylline and Venous Insufficiency
| Article | Year |
|---|---|
Effect of oral pentoxifylline therapy on venous lower extremity ulcers due to deep venous incompetence.
Topics: Administration, Oral; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Pentoxifylline | 1989 |
Nonhealing venous stasis ulcers. Pentoxifylline as adjunctive therapy.
Topics: Aged; Humans; Leg Ulcer; Male; Pentoxifylline; Theobromine; Venous Insufficiency | 1987 |