indomethacin has been researched along with Meningitis, Pneumococcal in 3 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Meningitis, Pneumococcal: An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of indomethacin on central nervous system abnormalities in rabbits with experimental pneumococcal meningitis were studied." | 3.68 | Effect of indomethacin on the pathophysiology of experimental meningitis in rabbits. ( Sande, MA; Täuber, MG; Tureen, JH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tureen, JH | 1 |
| Täuber, MG | 1 |
| Sande, MA | 1 |
| Kadurugamuwa, JL | 1 |
| Hengstler, B | 2 |
| Zak, O | 2 |
| Tuomanen, E | 1 |
| Rich, R | 1 |
| Bray, MA | 1 |
| Tomasz, A | 1 |
3 other studies available for indomethacin and Meningitis, Pneumococcal
| Article | Year |
|---|---|
Effect of indomethacin on the pathophysiology of experimental meningitis in rabbits.
Topics: Animals; Brain Edema; Dinoprostone; Disease Models, Animal; Indomethacin; Meningitis, Pneumococcal; | 1991 |
Cerebrospinal fluid protein profile in experimental pneumococcal meningitis and its alteration by ampicillin and anti-inflammatory agents.
Topics: Ampicillin; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cerebrospina | 1989 |
Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis.
Topics: Ampicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteriolysis; Cell Wall; Cerebrospina | 1987 |