metformin has been researched along with Meningitis, Pneumococcal in 1 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Meningitis, Pneumococcal: An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss." | 5.51 | Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. ( Grandgirard, D; Le, ND; Leib, SL; Muri, L; Zemp, J, 2019) |
| "Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss." | 1.51 | Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. ( Grandgirard, D; Le, ND; Leib, SL; Muri, L; Zemp, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muri, L | 1 |
| Le, ND | 1 |
| Zemp, J | 1 |
| Grandgirard, D | 1 |
| Leib, SL | 1 |
1 other study available for metformin and Meningitis, Pneumococcal
| Article | Year |
|---|---|
Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Ceftriaxone; Cytokines; Disease Models, Animal; Drug Ther | 2019 |